Search clinical trials for: Placebo to sitagliptin

Total 60683 results

Daiichi Sankyo Co., Ltd.

Completed

A Phase 2 Study of DS-8500a in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)

Type2 Diabetes Mellitus

Japan
GlaxoSmithKline

Completed

A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

Diabetes Mellitus, Type 2

United States
Merck Sharp & Dohme LLC

Completed

Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)

Type 2 Diabetes Mellitus
University of British Columbia

Terminated

Sitagliptin in Cystic Fibrosis-Related Diabetes

Cystic Fibrosis

Canada
Khoo Teck Puat Hospital

Completed

Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment

Type II Diabetes in Subjects BMI 27 to 32

Singapore
Genuine Research Center, Egypt
Eva Pharma

Completed

Bioequivalence Study of of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands)

Healthy

Egypt
Bio-innova Co., Ltd

Not yet recruiting

Sitagliptin and Metformin Hydrochloride Tablets 50 mg/1000 mg Relative to Originator

Healthy Subjects
Merck Sharp & Dohme LLC

Completed

Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189)

Diabetes Mellitus, Non-Insulin-Dependent
Hoffmann-La Roche

Completed

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

China
Universidade Federal do Ceará

Completed

Effects of Auriculotherapy on Pain and Functional Capacity of Individuals With Chikungunya Fever

Chikungunya Fever

Brazil
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of BI 113608 in Healthy Male Volunteers

Healthy

Germany
Boehringer Ingelheim

Completed

Dose Proportionality of Different Dose Strengths of Linagliptin Tablets After Oral Administration to Healthy Male and Female Volunteers

Healthy
Gilead Sciences
Galapagos NV

Completed

Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy (FINCH 3)

Rheumatoid Arthritis

United States, Italy, Poland, Ukraine, Belgium, Hong Kong, Taiwan, Spain, Bulgaria, India, Malaysia, Romania, Serbia, South Africa, Korea, Republic of, Japan, Australia, Chile, Russian Federation, Argentina, Germany, New Zealand, Th... and more
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)

Type 2 Diabetes Mellitus
Sheikh Zayed Federal Postgraduate Medical Institute

Completed

Effect of Apple Cider Vinegar in Type 2 Diabetics

Diabetes Mellitus | Randomized Controlled Trial

Pakistan
Nicolai Jacob Wewer Albrechtsen

Completed

The Effects of Neprilysin on Glucagon-like Peptide-1 (NEP)

Heart Failure | Diabetes

Denmark
Merck Sharp & Dohme LLC

Completed

MK-0431 Early Phase II Double-blind Study - Type 2 Diabetes Mellitus (0431-043)

Type 2 Diabetes Mellitus
Janssen Research & Development, LLC

Completed

The CANTATA-M (CANagliflozin Treatment and Trial Analysis - Monotherapy) Trial

Diabetes Mellitus, Type 2

United States, Colombia, Mexico, Poland, Spain, India, Malaysia, Romania, South Africa, Sweden, Korea, Republic of, Estonia, Puerto Rico, Austria, Lithuania, Philippines, Guatemala, Iceland
Pfizer

Completed

Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States, Hungary, Taiwan, Romania, India, South Africa, Philippines, Slovakia
ACELYRIN Inc.

Completed

Hidradenitis Suppurativa Phase 2b Pivotal Study of Izokibep

Hidradenitis Suppurativa

United States, Canada, Germany, Hungary, Poland, Spain
Theratocular Biotek Co.
Novotech (Australia) Pty Limited

Active, not recruiting

A Study to Investigate the Effect of IOP-lowering With TO-O-1001 Eye Drops in Healthy Subjects and in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open Angle Glaucoma

Australia
Pennington Biomedical Research Center
THE C.B. AND IRENE PENNINGTON FOUNDATION

Completed

Postpartum Weight Loss and Exercise (PRIDE) (PRIDE)

Glucose Intolerance | Gestational Diabetes

United States
SecuraBio

Completed

A Phase 2a, Efficacy and Safety Study of Duvelisib in Mild Asthmatic Subjects

Asthma

Germany, United Kingdom
AstraZeneca

Completed

Esophageal Hypersensitivity Study in Patients With Gastroesophageal Reflux Disease (GERD)

Sensitivity in Esophagus

Denmark, Sweden
Merck Sharp & Dohme LLC

Completed

Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)

Type 2 Diabetes Mellitus
Vanderbilt University

Completed

Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome

Hypertension | Metabolic Syndrome

United States
ACELYRIN Inc.

Active, not recruiting

Psoriatic Arthritis Study of Izokibep

Psoriatic Arthritis

United States, Bulgaria, Canada, Czechia, Germany, Hungary, Poland, Spain
Novartis Pharmaceuticals

Completed

To Assess Safety, Tolerability and Efficacy of LJN452 in Patients With Primary Bile Acid Diarrhea.

Primary Bile Acid Diarrhea

United States, United Kingdom
AstraZeneca

Completed

Study to Investigate Multiple Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects

Healthy

United States
AstraZeneca

Terminated

A First Time in Man Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD1979 in Healthy Males

Healthy Subjects

United States
Merck Sharp & Dohme LLC

Completed

Study to Compare Sitagliptin Versus Sulfonylurea Treatment During Ramadan Fasting in Patients With Type 2 Diabetes (MK-0431-262)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

MK-0954E Phase III Long-Term Study in Participants With Hypertension (MK-0954E-356)

Hypertension
The Affiliated Hospital of Qingdao University

Completed

Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects

Healthy Subjects

China
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Recruiting

A Study of TQH2722 Injection to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Immunogenicity in Healthy Adult Subjects

Atopic Dermatitis

China
Kessler Foundation

Recruiting

Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS (STEM)

Multiple Sclerosis

United States
Vir Biotechnology, Inc.
GlaxoSmithKline

Completed

A Study to Investigate the PK, Safety, and Tolerability of Sotrovimab vs Placebo Administered IV or IM in Japanese and Caucasian Participants

Covid19

United States
Merck Sharp & Dohme LLC

Completed

A Dose Finding Study of Preladenant (SCH 420814) for the Treatment of Parkinson's Disease (PD) in Japanese Patients (P06402)

Parkinson's Disease
AstraZeneca

Completed

A Study of AZD4901 in Females With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome (PCOS), Female Endocrine Disorder

United States, United Kingdom, Germany
IlDong Pharmaceutical Co Ltd

Recruiting

IDG-16177 for the Evaluation of Its Safety and Pharmacokinetics

Type 2 Diabetes

Germany
Aswan University Hospital

Unknown

Role of 200 mg Versus 400mg Vaginal Progesterone in Prevention of Preterm Labor in Twin Gestation

Twin; Pregnancy, Affecting Fetus or Newborn

Egypt
Organon and Co

Completed

MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)

Hypertension
Amsterdam UMC, location VUmc

Completed

Sitagliptin Prophylaxis for Glucocorticoid-Induced Impairment of Glucose Metabolism in Males With the Metabolic Syndrome (SPHINX)

Diabetes Mellitus | Steroid Diabetes | Glucocorticoid-induced Diabetes | Beta-cell Function

Netherlands
Merck Sharp & Dohme LLC

Completed

A Study of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus With Chronic Kidney Disease or Kidney Failure on Dialysis (MK-3102-019)

Type 2 Diabetes Mellitus
Southern California College of Optometry at Marshall...

Recruiting

Eyelid Androgen Treatment in Dry Eye

Aqueous Tear Deficiency | Meibomian Gland Dysfunction of Bilateral Eyes (Disorder)

United States
Columbia University
National Institute on Aging (NIA); Harvard School of Public Health (HSPH); National...

Completed

The Effect of De-Prescribing Antipsychotics on Health and Quality of Life for People With Dementia

Dementia | Alzheimer Disease | Prescribing, Off-Label

United States
Merck Sharp & Dohme LLC

Completed

Letermovir Versus Valganciclovir to Prevent Human Cytomegalovirus Disease in Kidney Transplant Recipients (MK-8228-002)

CMV Disease

United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, France, Germany, Hungary, Italy, Mexico, New Zealand, Poland, Spain, United Kingdom
Gangnam Severance Hospital

Completed

Effect of Oral Carbohydrate on Serum S-100β Protein and Development of Postoperative Delirium in Elderly Patients

Inflammation | Delirium | Insulin Resistance
Boehringer Ingelheim
Eli Lilly and Company

Completed

Linagliptin as Add on to Basal Insulin in the Elderly

Diabetes Mellitus, Type 2

United States, New Zealand, Spain, Japan, Finland, Germany, Greece, Romania, South Africa, Denmark, Colombia, Poland, United Kingdom, Mexico, Australia, Belgium, Ireland
Boehringer Ingelheim
Eli Lilly and Company

Completed

Efficacy and Safety of Linagliptin in Elderly Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Australia, Canada, Denmark, Netherlands, Sweden
AstraZeneca

Completed

Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

Diabetes Mellitus, Type 2

United States, Canada, Mexico, Puerto Rico, Taiwan, Australia

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