Search clinical trials for: Placebo (semaglutide)

Total 53924 results

Novo Nordisk A/S

Completed

Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial

Diabetes Mellitus, Type 2

United States
Novo Nordisk A/S

Withdrawn

SUSTAIN SWITCH: A Research Study to Compare Two Dose Schedules of Semaglutide Taken Once Weekly in People With Type 2 Diabetes (SUSTAIN SWITCH)

Diabetes Mellitus, Type 2

United States, Sweden, Austria, Finland
Eli Lilly and Company

Completed

A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

Germany
Jens D Hove, MD,PHD

Recruiting

Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure (FIT-HF)

Obesity | Weight Loss | Chronic Heart Failure | Heart Failure With Reduced Ejection Fraction

Denmark
Massachusetts General Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH (GLUCOSE-MGH)

Metabolic Diseases | Type 2 Diabetes | Genetic Predisposition

United States
Novo Nordisk A/S

Active, not recruiting

A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE) (REALYSE)

Diabetes Mellitus, Type 2

United States
Sabyasachi Sen

Completed

Impact of Semaglutide on CD34+ EPC and Fat Derived MSC

Diabetes Mellitus, Type 2

United States
Shenzhen Institute of Advanced Technology, Chinese...

Recruiting

The Effect of Weekly Semaglutide Treatment on Energy Expenditure

Obesity; Drug

China
Eli Lilly and Company
Versanis Bio, Inc.

Active, not recruiting

Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or Obese

Obesity | Obese | Overweight or Obesity

United States, Australia, New Zealand
Novo Nordisk A/S

Completed

Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus

Obesity | Metabolism and Nutrition Disorder

United States, Israel, Russian Federation, United Kingdom, Canada, Belgium, Germany, Australia
The University of Hong Kong

Not yet recruiting

GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac Surgery (GLUMINS)

Myocardial Injury

China
University of California, Los Angeles

Recruiting

Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.

Obesity

United States
Novo Nordisk A/S

Recruiting

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels (REDEFINE 3)

Cardiovascular Disease

Netherlands, Australia, Italy, United States, Serbia, Spain, United Kingdom, Thailand, India, Malaysia, Turkey, Mexico, Canada, Argentina, Germany, France, Poland, South Africa, Brazil, Bulgaria, Colombia, Denmark, Ireland, Japan
Novo Nordisk A/S

Completed

Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus (PIONEER 4)

Diabetes Mellitus, Type 2 | Diabetes

United States, Poland, Croatia, Japan, Slovakia, Germany, Latvia, South Africa, Czechia, United Arab Emirates, Hungary, Ukraine, Puerto Rico
Novo Nordisk A/S

Completed

Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

United States, Russian Federation, United Kingdom, Canada, Austria, Serbia, Germany, South Africa, Malaysia, Czechia
Novo Nordisk A/S

Completed

A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and Liraglutide

Diabetes Mellitus, Type 2 | Diabetes

India, Italy, Spain, Austria, Finland, Hungary, Turkey, France, United Kingdom, Switzerland, Bulgaria, Germany, South Africa, Former Serbia and Montenegro
Peking University First Hospital

Recruiting

Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome

Semaglutide | PCOS (Polycystic Ovary Syndrome)

China
Canadian Medical and Surgical Knowledge Translation...
Unity Health Toronto; Western University, Canada

Recruiting

Semaglutide and Vascular Regeneration (SEMA-VR)

Cardiovascular Diseases | Obesity | Diabetes Mellitus, Type 2 | Atherosclerosis

Canada
Aga Khan University
Rehman Medical Institute - RMI

Recruiting

"Efficacy of Once Weekly GLP 1 Analogue: Semaglutide. A Multicenter Experience From Pakistan."

Diabetes Mellitus, Type 2 | Weight Change, Body

Pakistan
University of Maryland, Baltimore

Recruiting

Pharmacogenetics of Response to GLP1R Agonists (PORT)

Obesity | Diabetes Type 2

United States
LMC Diabetes & Endocrinology Ltd.

Completed

Real-world Health Outcomes in Canadian Patients Using Semaglutide

Type 2 Diabetes

Canada
Psychiatric Centre Rigshospitalet
Neurobiology Research Unit

Recruiting

Does Semaglutide Reduce Alcohol Intake in Patients With Alcohol Use Disorder and Comorbid Obesity? (SEMALCO)

Alcohol Dependence | Alcohol Use Disorder | Alcohol Abuse | Alcohol Addiction

Denmark
Shanghai Yinnuo Pharmaceutical Technology Co.,...

Active, not recruiting

A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment

Type2 Diabetes

China
Ministry of Health, Saudi Arabia

Not yet recruiting

Semaglutide GLP1 Agonists With Degludec Basal-bolus Insulin in Early Type 1 Diabetes to Basal-bolus

Type 1 Diabetes
University of Copenhagen

Unknown

Exercise and GLP-1 RA on Insulin Secretion (EXISECRET)

Type 2 Diabetes

Denmark
University of Colorado, Denver
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome (RESTORE)

Obese | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

United States
Brigham and Women's Hospital

Completed

Replication of the SEPRA Diabetes Trial in Healthcare Claims Data

Diabetes Mellitus, Type 2

United States
Novo Nordisk A/S

Completed

A Research Study to Look at How Insulin 287 and Semaglutide Work in the Body of People With Type 2 Diabetes When Taken Alone or Together

Diabetes Mellitus, Type 2

Germany
Novo Nordisk A/S

Completed

Safety and Efficacy of Oral Semaglutide Versus Dulaglutide Both in Combination With One OAD (Oral Antidiabetic Drug) in Japanese Subjects With Type 2 Diabetes (PIONEER 10)

Diabetes Mellitus, Type 2 | Diabetes

Japan
Academisch Medisch Centrum - Universiteit van Amsterdam...
Endogenex

Recruiting

A Trial to Evaluate Safety, Feasibility and Efficacy of the ReCET Procedure (EMINENT-2) (EMINENT-2)

Diabetes Mellitus, Type 2

Netherlands
University Medical Centre Ljubljana
University of Palermo

Recruiting

Semaglutide Anti-Atherosclerotic Mechanisms of Action Study in Type 2 Diabetes Patients (SAMAS)

Diabetes Mellitus, Type 2 | Atherosclerosis

Slovenia
Mayo Clinic
United States Department of Defense

Recruiting

Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction

Obesity | Cardiomyopathy | Heart Failure With Preserved Ejection Fraction (HFpEF)

United States
Michael John Robertson
Novartis

Completed

Recombinant Human IL-18 and Ofatumumab After PBSCT for Lymphoma

Non-Hodgkin's Lymphoma

United States
University of Nottingham
Medical Research Council

Recruiting

Glucagon-like Peptide-1 Agonism With Very Low Calorie Diets (SemVLCD)

Type 2 Diabetes Mellitus in Obese

United Kingdom
University College Dublin
University of Copenhagen; Rush University Medical Center

Recruiting

Semaglutide's Efficacy in Achieving Weight Loss for Those With HIV (SWIFT)

Obesity | HIV-1-infection

Ireland
Novo Nordisk A/S

Completed

Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide sc

Obesity | Diabetes Mellitus, Type 2 | Overweight | Healthy Volunteers

Netherlands
Innovative Medical

Completed

Diurnal Curves With Bimatoprost 0.03% Versus Travoprost 0.004%

Glaucoma

United States
Merck Sharp & Dohme LLC

Recruiting

A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013)

Non-alcoholic Fatty Liver Disease | NAFLD | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis | Fatty Liver, Nonalcoholic

Canada, United States, Puerto Rico, Japan, Korea, Republic of, Taiwan, Spain, Israel, Chile, France, Italy, Hungary, Switzerland, Belgium, China, Singapore, Czechia, Portugal, Austria, United Kingdom, Thailand, Hong Kong, Turkey, Colo...
Centre for Addiction and Mental Health

Recruiting

Semaglutide in Comorbid Schizophrenia Spectrum Disorder and Obesity (Sema)

Schizophrenia Spectrum Disorders

Canada
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Unknown

Effect and Safety of Benaglutide or Metformin in Patients With Simple Obesity Who Have Inadequate Weight Control

Obesity; Drug

China
Centre Hospitalier Universitaire Dijon

Active, not recruiting

Effect of Weekly GLP1 Agonist Treatment in "Double Diabetes" (TOLEDDO)

Double Diabetes

France
Srinvasan Beddhu
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Stanford...

Recruiting

Sit Less, Interact and Move More (SLIMM) 2 Study

Obesity | Chronic Kidney Diseases

United States
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Semaglutide for Alcohol Use Disorder

Alcohol Use Disorder | Cigarette Smoking

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Semaglutide Versus Dulaglutide as add-on to Metformin in Subjects With Type 2 Diabetes. (SUSTAIN 7)

Diabetes Mellitus, Type 2 | Diabetes

United States, Croatia, India, Slovakia, Spain, United Kingdom, Finland, Ireland, Germany, Greece, Puerto Rico, Romania, Bulgaria, Latvia, Hong Kong, Lithuania, Portugal
Hvidovre University Hospital

Recruiting

Semaglutide and Physical Activity for Obesity and Multimorbidity

Obesity | Multimorbidity | Obesity Morbid

Denmark
University Medical Center, Kazakhstan
Nazarbayev University; Astana Medical University; Ministry of Science and Higher... and other collaborators

Recruiting

Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome

Metabolic Syndrome

Kazakhstan
Novo Nordisk A/S

Completed

Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes (SUSTAIN™ 4)

Diabetes Mellitus, Type 2 | Diabetes

United States, Croatia, India, Slovakia, United Kingdom, France, Argentina, South Africa, Germany, Slovenia, Netherlands, Romania, North Macedonia, Mexico, Puerto Rico
Pichamol Jirapinyo, MD, MPH

Not yet recruiting

ESG vs GLP-1RA vs ESG + GLP-1RA in Patients With Obesity, NAFLD and Advanced Fibrosis: A Randomized Controlled Trial

Liver Diseases | Metabolic Diseases | Obesity | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Insulin Resistance | Weight Loss | Liver Fat | NAFLD | Insulin Sensitivity/Resistance | Insulin Sensitivity | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Non-alcoholic Steatohepatitis | Non Alcoholic Fatty... and other conditions

United States
Eli Lilly and Company

Completed

A Study Comparing the Dulaglutide Pen and the Semaglutide Pen

Diabetes Mellitus, Type 2

United States
Regeneron Pharmaceuticals

Active, not recruiting

A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss and Fat Loss (COURAGE)

Obesity

United States

Search clinical trials for: Placebo (semaglutide)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Slovenia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations