Search clinical trials for: Placebo (single dose)

Total 60595 results

Hoffmann-La Roche

Completed

A Study With RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
TRB Chemedica International SA

Not yet recruiting

Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease (BUSTON-01)

Dry Eye Disease
TRB Chemedica International SA

Not yet recruiting

Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease (BUSTON-02)

Dry Eye Disease
Israel Institute for Biological Research (IIBR)

Completed

Evaluate the Safety, Immunogenicity and Potential Efficacy of an rVSV-SARS-CoV-2-S Vaccine

Covid19

Israel
Human Genome Sciences Inc.
GlaxoSmithKline

Completed

Study of Belimumab Administered Subcutaneously to Healthy Subjects

Healthy

United States
Acerus Pharmaceuticals Corporation

Completed

PK Study of Testosterone Nasal Gel (TBS-2) in Healthy Premenopausal Women

Female Sexual Dysfunction

United States
University Health Network, Toronto
Centre for Addiction and Mental Health

Recruiting

Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin (PSI-1V2)

Depression | Mood Disorders | Major Depressive Disorder | Treatment-Resistant Depression

Canada
Enterprise Therapeutics Ltd

Completed

A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects

Healthy

United Kingdom
Pfizer

Completed

A Study to Investigate the Effect of Tablet Formulation and Food on PF-07104091 in Healthy Participants

Healthy

United States
Bayer

Completed

A Study to Learn How the Study Treatment BAY3283142 Taken as Single Dose by Mouth Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Reduced Kidney Function Compared to Participants With Normal Kidney Function of Similar Age, Gender, and Weight

Renal Impairment | Chronic Kidney Disease | Healthy Volunteers

Germany
Institute of Medical Biology, Chinese Academy of...
Guangxi Center for Disease Control and Prevention

Completed

Clinic Trial to Evaluate the Safety and Immunogenicity by Different Sequential Schedules of bOPV and IPV

Poliomyelitis

China
Cloudbreak Therapeutics, LLC

Completed

Safety and Efficacy of CBT-001 Ophthalmic Solution in Patients With Pterygium (Pterygium)

Pterygium

United States
Frequency Therapeutics

Completed

FX-322 in Adults With Stable Sensorineural Hearing Loss

Sensorineural Hearing Loss | Noise Induced Hearing Loss | Sudden Sensorineural Hearing Loss

United States
University of Oxford

Unknown

A Study of a Candidate COVID-19 Vaccine (COV003)

Coronavirus

Brazil
Radboud University Medical Center

Completed

the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia (RISPENDO)

Autoimmune Diseases | Infection

Netherlands
The Cleveland Clinic

Completed

Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection

Overactive Bladder | Urge Incontinence | Urinary Incontinence, Urge | Overactive Bladder Syndrome

United States
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of Increasing Doses of BIBN 4096 BS in Healthy Male and Female Volunteers

Healthy
Centre Francois Baclesse
Association de Neuro-Oncologues d'Expression Francaise

Active, not recruiting

Stereotactic Radiotherapy in Oligometastatic Brain Disease: a Randomised Phase III Study Comparing Hypofractionated Stereotactic Radiation Therapy (3*10 Gy) to the Historical Single-dose Radiosurgery (1*20 to 25 Gy) With Medico-economic Evaluation. (OligoBM-01)

Brain Metastasis | Oligoprogression

France
Contrad Swiss SA

Completed

Evaluation of the Effect of the "CR500 SINGLE-DOSE GEL" Medical Device in Patients With Knee Osteoarthritis (KOA)

Knee Osteoarthritis

Italy
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Non-fasting Conditions

Healthy

United States
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of APL-1501 Extended Release (ER) Capsules Compared to APL-1202 Immediate Release (IR) Tablets in Healthy Volunteers

Bladder Cancer

Australia
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
Indiana University
The National Center for Complementary and Integrative Health

Recruiting

Drug-gene-nutraceutical Interactions of Cannabidiol and Tacrolimus

Kidney Disease, Chronic | CBD | Transplant Complication

United States
Contrad Swiss SA

Completed

Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function

Knee Osteoarthritis | Knee Injuries | Pain, Acute | Knee Arthritis | Pain, Chronic | Knee Pain Swelling

Italy
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Safety and Efficacy Study of SHR4640 and Febuxostat in Subjects With Hyperuricemia

Hyperuricemia
Air Force Military Medical University, China

Completed

Effect of Single Dose of 2L PEG on Bowel Preparation in Average-risk Patients Undergoing Colonoscopy

Health Behavior

China
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
University of the West of England
University of Hawaii; Indonesia University; Unilever R&D; UNICEF

Completed

Evaluating Dove Confident Me Single Session in Indonesia

Body Image

United Kingdom
Meissa Vaccines, Inc.

Recruiting

Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults

Covid19

United States
Urovant Sciences GmbH
Dasman Diabetes Institute; Ion Channel Innovations

Completed

Phase 2A Clinical Trial Evaluating the Potential Activity and Safety of hMaxi-K Gene for ED

Erectile Dysfunction

Kuwait
Stoke Therapeutics, Inc

Completed

An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome

Dravet Syndrome

United States
J L Marsh
United States Department of Defense

Completed

Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA

Osteoarthritis | Post-traumatic Osteoarthritis

United States
Laboratorios Silanes S.A. de C.V.

Completed

Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers (NTC00940472)

Healthy

Spain
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Non-fasting Conditions

Healthy

United States
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Massachusetts General Hospital; Stanford University

Completed

Randomized Study Comparing Local Tumor Control After Post-Operative Single-Fraction or Hypofractionated Stereotactic Radiosurgery in the Treatment of Spinal Metastases

Spinal Metastases

United States
Prana Biotechnology Limited

Completed

Absorption, Metabolism and Excretion Study of [14C]PBT2 and Absolute Bioavailability of PBT2

Healthy Volunteers

United Kingdom
Fundacao Champalimaud

Unknown

Single Dose Radiotherapy (SDRT) With or Without Adjuvant Systemic Therapy for Oligometastatic Prostate Cancer

Metastatic Prostate Cancer | Prostate Adenocarcinoma

Portugal
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions

Healthy

United States
NP Therapeutics

Completed

Study to Assess Safety, Tolerability and Pharmacokinetics of XC7 (Which is Planned Use in the Treatment of COVID-19) in Healthy Volunteers

Covid19 | Healthy Volunteers

Russian Federation
Shanghai BDgene Co., Ltd.
Eye & ENT Hospital of Fudan University

Completed

Safety and Efficacy of CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy to Treat Refractory Viral Keratitis

Cornea | Herpes Simplex Virus Infection | Viral Keratitis | Blindness Eye

China
AstraZeneca

Completed

A Study to Assess the Relative Bioavailability of Process Variants of Selumetinib in Healthy Male Volunteers

Healthy Volunteers Bioequivalence or Bioavailability Study

United Kingdom
Megalabs

Not yet recruiting

Biosimilarity Study of Subcutaneous Recombinant Human Erythropoietin in Healthy Volunteers

Healthy
Tiedra Farmacéutica SL
Hospital Universitario Principe de Asturias

Unknown

Efficacy and Tolerance of Hypertonic Sodium Chloride (NaCl 5%) Eye Drops Without Preservatives in Corneal Edema

Corneal Edema

Spain
Actavis Inc.

Completed

A Relative Bioavailability Study of Griseofulvin 125 mg/5 mL Suspension Under Fasting Conditions

Healthy

Canada
Sinovac Biotech Co., Ltd

Completed

Studies of the Safety and Immunogenicity of a Sabin Inactivated Poliovirus Vaccine

Poliomyelitis

China
MicuRx
Worldwide Clinical Trials

Completed

Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4

Safety
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Griseofulvin 125 mg/5 mL Suspension Under Non-fasting Conditions

Healthy

Canada
Melinta Therapeutics, Inc.

Completed

Drug-Drug Interaction Potential of Orbactiv (Oritavancin) Co-Administered With Warfarin in Healthy Subjects

Healthy

United States
Société des Produits Nestlé (SPN)

Completed

Oral CDX-7108 in Healthy Adults and EPI Subjects

Exocrine Pancreatic Insufficiency

Australia, New Zealand

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