Search clinical trials for: Placebo Comparator: Placebo

Total 54728 results

Tris Pharma, Inc.

Completed

Cebranopadol Effects on Ventilatory Drive, Central Nervous System (CNS) and Pain.

Pain

Netherlands
Merck Sharp & Dohme LLC

Completed

Prevention of Human Papillomavirus (HPV) in 20 to 45 Year Old Chinese Women (V501-041)

HPV Infections
The University of Texas Medical Branch, Galveston

Terminated

Hormonal Status on Blood Flow and Tissue in Pelvic Organ Prolapse

Pelvic Floor Disorders

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Greater Washington Community Foundation

Terminated

Muscadine Plus (MPX) In Men With Prostate Cancer

Adenocarcinoma of the Prostate

United States
Novartis Pharmaceuticals

Completed

A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ORION-5)

Homozygous Familial Hypercholesterolemia

Hong Kong, Israel, Russian Federation, Serbia, South Africa, Taiwan, Turkey, Ukraine
RenJi Hospital
Shanghai Jiao Tong University School of Medicine

Recruiting

Effect on Early Cognition Under Sedation by Rimazole Toluenesulfonate in Old Patient Undergoing Colonoscopy

Cognition

China
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Withdrawn

Anti-IL-1 Treatment in Children Diabetic Keto-Acidosis (DKA) at Diagnosis of Type 1 Diabetes

Type I Diabetes

United States
NovaCardia, Inc.
Merck Sharp & Dohme LLC

Completed

Placebo-Controlled Randomized Study of KW-3902 for Subjects Hospitalized With Worsening Renal Function and Heart Failure Requiring IV Therapy (REACH UP)

Heart Failure, Congestive
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS) (ARCH-MS)

Hypertension | Overweight | Dyslipidemias | Prediabetic State | Metabolic Syndrome X

United States
Aswan University Hospital

Completed

Tranexamic Acid for the Control of Blood Loss at Elective Cesarean Section

Cesarean Section Complications

Egypt
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA); GlaxoSmithKline; Mclean Hospital

Completed

Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking

Nicotine Dependence

United States
National University of Natural Medicine

Recruiting

Zypan Functional Dyspepsia

Dyspepsia

United States
Centre Hospitalier Intercommunal Creteil

Recruiting

Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults (SOPAZITHRO)

Sinusitis, Chronic | Sinus Infection Chronic

France
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Study to Evaluate the Safety and Immunogenicity of an Oral HIV Vaccine in Healthy, HIV-uninfected Adults

Healthy Volunteer | HIV Vaccine

United States
Carmot Therapeutics, Inc.

Completed

A Study to Assess CT-868 and the Relationship Between Insulin Secretory Response and Ambient Blood Glucose.

Diabetes

United States
Merck Sharp & Dohme LLC

Completed

An Investigational Study of Gardasil™ (qHPV Vaccine) in Reducing the Incidence of Anogenital Warts in Young Men (V501-020)

Condylomata Acuminata
Merck Sharp & Dohme LLC

Completed

V501 Immunogenicity Study in Females Age 9 to 17 Years (V501-028)

HPV Infections
B. Braun Medical Inc.

Withdrawn

Prontosan Versus Saline in the Cleansing of Chronic Leg Ulcers in Diabetic Patients

Diabetic Complications

United States
Xigo Health LLC

Completed

Safety and Efficacy Study of Oral XIGO Tablets to Treat The Common Cold

Common Cold

United States
Aswan University Hospital

Completed

Reducing Blood Loss During Cesarean Section by Topical Versus IV Tranexamic Acid

Cesarean Section Complications

Egypt
Merck Sharp & Dohme LLC

Completed

A Study of MK0657 in Parkinson's Disease Patients (0657-006)

Parkinson's Disease
Aswan University Hospital

Unknown

Sublingual Misoprostol With or Without Intravenous Tranexamic Acid During Hemorrhagic Cesarean Section

Cesarean Section Complications

Egypt
Organon and Co

Completed

Obese Hypertension Study (0954-315)

Hypertension
Texas Tech University Health Sciences Center

Terminated

Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion

Low Back Pain

United States
GUSTAVO SALGUERO
Hospital Infantil Universitario de San Jose

Not yet recruiting

Cartilage Recovery in Adults With Knee Osteorthritis by Mesenchymal Cell Therapy: Randomized Trial of Radiologic and Clinical Outcomes (INMUNOCEM-OA)

Knee Osteoarthritis
National Institute of Allergy and Infectious Diseases...
Gilead Sciences

Completed

GS-5734 to Assess the Antiviral Activity, Longer-Term Clearance of Ebola Virus, and Safety in Male Ebola Survivors With Evidence of Ebola Virus Persistence in Semen

Ebola

Guinea, Liberia
Spectrum Health Hospitals

Terminated

TXA Study in Major Burn Surgery

Burn | Major Surgery | Tranexamic Acid

United States
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Nitrites, Exercise, and Peripheral Arterial Disease (NO-PAD)

Peripheral Arterial Disease

United States
Mlinotest Zivilska Industrija d.d.
University Medical Centre Ljubljana; University of Ljubljana

Completed

Impact of Consumption of Beta-glucans on the Intestinal Microbiota and Glucose and Lipid Metabolism

Hyperglycemia | Hypertension | Metabolic Syndrome | Dyslipidemia | Obesity, Abdominal

Slovenia
Institute of Vaccines and Medical Biologicals,...
Department of Health and Human Services; Institut Pasteur; PATH; World Health Organization

Completed

Influenza A/H5N1 Vaccine Clinical Trial (IVACFLU-A/H5N1) - Phase 1

Influenza A Subtype H5N1 Infection

Vietnam
Duke University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD (DM+PAD)

Peripheral Arterial Disease | Type II Diabetes Mellitus

United States
University of Missouri, Kansas City
Reliant Pharmaceuticals; Saint Luke's Health System Foundation; Truman Medical...

Withdrawn

Use of Omega-3 Fatty Acids (Fish Oil) in Patients With Chronic Hepatitis C Infection

Hepatitis C

United States
Karolinska Institutet

Completed

Insulin Sensitivity and Beta Cell Function After Carbohydrate Loading in Hip Replacement Surgery

Insulin Sensitivity

Sweden
Cedars-Sinai Medical Center
National Institute of Mental Health (NIMH); Massachusetts General Hospital

Completed

Omega-3 Fatty Acids for Treating Adults With Major Depression

Depression

United States
Contera Pharma
Bukwang Pharmaceutical

Active, not recruiting

A Study in Parkinson's Disease in Patients With Moderate to Severe Dyskinesia (ASTORIA)

Dyskinesias

France, Germany, Italy, Korea, Republic of, Spain
University of California, San Diego

Terminated

Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC (ILEUS)

Ileus

United States
Novartis

Completed

Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects With Acute Blunt Trauma Injuries

Acute Blunt Soft Tissue Injuries/Contusions

United States
Fengmei Lian
Peking Union Medical College Hospital; Huashan Hospital; Chengdu University of... and other collaborators

Unknown

Post-marketing Evaluation of Mudan Granule Intervention on Type 2 Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy Type 2

China
Organon and Co

Completed

Montelukast Compared With Placebo and Salmeterol in Exercise-Induced Bronchoconstriction (0476-316)

Asthma, Exercise-Induced
3D Medicines (Sichuan) Co., Ltd.

Recruiting

Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC

Non-small Cell Lung Cancer

China
Novartis Pharmaceuticals

Completed

Efficacy at 24 Weeks and Long Term Safety, Tolerability and Efficacy up to 2 Years of Secukinumab (AIN457) in Patients With Active Psoriatic Arthritis (PsA) (FUTURE 1)

Psoriatic Arthritis

Germany, United Kingdom, United States, Belgium, Philippines, Singapore, Thailand, Brazil, Czech Republic, Italy, Argentina, Israel, Russian Federation, Bulgaria, Romania, Australia, Canada, Poland, Slovakia
BioCryst Pharmaceuticals
Department of Health and Human Services

Terminated

A Study to Evaluate the Efficacy and Safety of Intravenous Peramivir in Subjects With Uncomplicated Influenza.

Influenza

United States
William Beaumont Hospitals

Terminated

Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis (PRONE)

Fibrosis, Liver | Cirrhosis, Liver | Steatohepatitis, Nonalcoholic | Fatty Liver Disease

United States
Vanderbilt University
Merck Sharp & Dohme LLC

Withdrawn

Vorapaxar and Lower Extremity Bypass Grafts

Peripheral Artery Disease
Merck Sharp & Dohme LLC

Completed

Biomarkers of Muscle Anabolism (MK-0000-082)

Muscle Anabolism
Merck Sharp & Dohme LLC

Completed

A Study of Safety and Efficacy of MK0859 (Anacetrapib) in Japanese Patients With Dyslipidemia (0859-029)

Dyslipidemia
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Antihypertensive Efficacy of MK0954

Hypertension
Loughborough University

Recruiting

Impact of Milk Fat Globule Membrane Supplementation on Heart and Brain Health

Cardiovascular Diseases | Overweight and Obesity | Cognition

United Kingdom
Actelion

Completed

Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation (SOPRANO)

Pulmonary Hypertension

United States
OcuCure Therapeutics, Inc.
Semler Research Center Pvt. Ltd.

Terminated

A Study Assessing Efficacy and Safety of OC-10X in the Treatment of PDR

Proliferative Diabetic Retinopathy (PDR)

Bangladesh

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