Search clinical trials for: Placebo multiple twice daily doses

Total 2551 results

Poznan University of Medical Sciences

Completed

Effect of Systematic Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery

Cerebral Palsy | Foot Diseases | Foot Deformities | Ankle Disease

Poland
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Active, not recruiting

A Phase III Clinical Study of the Efficacy and Safety of Two Low-concentration Atropine Sulfate Eye Drops (Mini-CHAMP)

Myopia

China
Janssen Research & Development, LLC

Completed

A Thorough QT Study of Aticaprant (JNJ-67953964) in Healthy Adult Participants

Healthy

Belgium
University of Minnesota

Completed

Characterizing and Predicting Drug Effects on Cognition

Cognitive Deficits

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants

Healthy

Belgium
GlaxoSmithKline

Completed

A Comparison Study Between the Fixed Dose Triple Combination of Fluticasone Furoate/ Umeclidinium/ Vilanterol Trifenatate (FF/UMEC/VI) With Budesonide/Formoterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Poland, Romania, Russian Federation, Ukraine, Bulgaria, Estonia, Mexico, Korea, Republic of, Slovakia, Greece, China, Italy, Hungary, Czechia
AB Science

Terminated

A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Patients With Relapse or Refractory Multiple Myeloma

Multiple Myeloma

United States, France
Eisai Inc.

Completed

Chronic Hepatitis C Virus Related Thrombocytopenia to Evaluate the Effects of E5501

Thrombocytopenia

United States
University of Washington
National Institute on Drug Abuse (NIDA); Kaiser Permanente

Completed

Strategies to Improve Pain and Enjoy Life (STRIPE)

Chronic Pain

United States
Alexza Pharmaceuticals, Inc.

Completed

Staccato Alprazolam Abuse Liability

Abuse Liability of Staccato Alprazolam

United States
University of Monastir

Completed

Low Versus High Dose Magnesium Sulfate in the Early Management of Rapid Atrial Fibrillation

Atrial Fibrillation

Tunisia
PETHEMA Foundation

Not yet recruiting

Treatment Protocol for Newky Diagnosed Adult Ph Positive ALL (LALPh2022)

Lymphoblastic Leukemia | Adult ALL | Philadelphia-Positive ALL
Allodynic Therapeutics, LLC

Completed

Low-Dose Naltrexone and Acetaminophen Combination in the Treatment of Chronic Low Back Pain (ANODYNE-4)

Chronic Low Back Pain | Lumbar Radiculopathy

United States
Texas Tech University
Texas Tech University Health Sciences Center

Completed

Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

United States
Chiesi Farmaceutici S.p.A.

Completed

A 24-wk Dose Ranging Study to Evaluate the Efficacy and Safety of 4 Doses of a New PDE4 Inhibitor in Patients With COPD (PIONEER)

Chronic Obstructive Pulmonary Disease
GlaxoSmithKline

Completed

A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis

Rhinitis, Allergic, Perennial

United States
Boryung Pharmaceutical Co., Ltd
Samsung Medical Center; Asan Medical Center; Chonnam National University Hospital and other collaborators

Completed

A Randomized, Double-Blind, Placebo-Controlled, 3x3 Factorial Design, Phase II Study to Evaluate the Antihypertensive Efficacy and Safety of Combination of Fimasartan and Amlodipine in Patients With Essential Hypertension

Hypertension

Korea, Republic of
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 1356 BS in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2
Praxis Precision Medicines

Completed

A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor (Essential1)

Essential Tremor

United States, Canada
Northwestern University
National Cancer Institute (NCI); Pfizer; University of California, San Francisco and other collaborators

Recruiting

The PROMISE Study: Duavee in Women With DCIS

Postmenopausal | Ductal Breast Carcinoma In Situ

United States
National Cancer Institute (NCI)

Terminated

Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

Lymphoma | Leukemia | Myeloproliferative Disorders | Myelodysplastic Syndrome | Multiple Myleoma

United States
KunWha Pharmaceutical Co., Ltd.

Unknown

Efficacy and Safety of KW21052 Compared to Lyrica in the Diabetic Patients With Neuropathic Pain

Diabetic Neuropathy

Korea, Republic of
Boehringer Ingelheim

Completed

Comparison of Safety and Efficacy of Berodual® Administered Via the Respimat® Device With That Administered Via the Metered Dose Inhaler (MDI) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
Boehringer Ingelheim
Pfizer

Completed

Evaluation of Tiotropium 2.5 and 5 mcg Once Daily Delivered Via the Respimat® Inhaler Compared to Placebo and Salmeterol HydroFluoroAlkane (HFA) Metered Dose Inhaler (MDI) (50 mcg Twice Daily) in Patient With Moderate Persistent Asthma II

Asthma

United States, Brazil, China, Colombia, Germany, India, Japan, Mexico, Peru, Poland, Romania
Sun Yat-sen University

Recruiting

Standard Chemotherapy Plus Moxifloxacin as First-line Treatment for Metastatic Triple-negative Breast Cancer

Triple Negative Breast Cancer

China
GlaxoSmithKline

Completed

Dose Ranging Study Evaluating the Efficacy and Safety of GSK2190915 Administered Once Daily

Asthma

United States, Japan, Romania, Ukraine, Bulgaria, Poland
Merck KGaA, Darmstadt, Germany

Terminated

Cancer Vaccine Study for Stage III, Unresectable, Non-small Cell Lung Cancer (NSCLC) in the Asian Population (INSPIRE)

Non-Small Cell Lung Cancer

Korea, Republic of, Taiwan, Singapore, China, Hong Kong
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., Japan

Completed

Study of Tecemotide (L-BLP25) in Participants With Stage III Unresectable Non-small Cell Lung Cancer (NSCLC) Following Primary Chemoradiotherapy

Non-small Cell Lung Cancer

Germany
Johnson & Johnson Consumer and Personal Products...
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

An Effectiveness and Safety Study of Acetaminophen 1000 mg and Ibuprofen 400 mg in Postoperative Dental Pain.

Pain
Ankara Diskapi Training and Research Hospital

Completed

Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia

Postoperative Pain After Knee Arthroscopy

Turkey
Cedars-Sinai Medical Center

Completed

A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques

Postoperative Pain | Crohn's Disease | Inflammatory Bowel Disease
Eli Lilly and Company
Algorithme Pharma Inc; CoLucid Pharmaceuticals; Cognitive Research Corporation

Completed

The Effects of Lasmiditan on Simulated Driving Performance - Healthy Participants

Migraine

Canada
Merck Sharp & Dohme LLC

Completed

Phase IIB 2-Period Crossover Polysomnography Study in Participants With Primary Insomnia (MK-4305-006)

Primary Insomnia
Merck Sharp & Dohme LLC

Completed

A Long Term Safety Study of Suvorexant in Participants With Primary Insomnia (MK-4305-009 AM3)

Insomnia
AEterna Zentaris
Dana-Farber Cancer Institute

Terminated

Assessment of Efficacy and Safety of Perifosine, Bortezomib and Dexamethasone in Multiple Myeloma Patients

Multiple Myeloma

Israel, Spain, Korea, Republic of, United States, Russian Federation, Canada, Ireland, Czechia, Slovakia
Medical University of Vienna

Completed

Effects of Vitamin C on Hyperoxia-Induced Reduction of Retinal Blood Flow

Ocular Physiology | Regional Blood Flow

Austria
US Department of Veterans Affairs

Completed

Role of Pain Modulation in GERD Patients Who Failed Standard Dose PPI

Gastroesophageal Reflux Disease

United States
Viatris Specialty LLC

Completed

Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users

Abuse Potential

United States
University of Georgia
The Hershey Company

Completed

Effect of Phytochemicals From Theobroma Cacao on Mental Energy

Mental Fatigue

United States
Pfizer

Completed

Study Conducted in Subjects With Rheumatoid Arthritis Who Have Moderate to Severe Disease Activity Despite Methotrexate Therapy With or Without Other Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)for at Least 12 Weeks Prior to Screening

Rheumatoid Arthritis

Hungary, Qatar, Romania, Ukraine, China, Czech Republic, Malaysia, Thailand, Lebanon, South Africa, Philippines, Brazil, Colombia, Egypt, Jordan, Mexico, Russian Federation, Taiwan, United Arab Emirates
Shanghai Celgen Bio-Pharmaceutical Co.,Ltd

Unknown

Safety and Efficacy Study of Etanercept (Qiangke®) to Treat Moderate to Severe Plaque Psoriasis

Psoriasis | Plaque Psoriasis

China
Radboud University Medical Center

Completed

Ticagrelor and Adenosine

Healthy

Netherlands
University of South Florida

Recruiting

Randomized Placebo-controlled Analysis of Superior Laryngeal Nerve Block for Neurogenic Cough

Cough | Nerve Block

United States
Otsuka Pharmaceutical Development & Commercialization...
Otsuka America Pharmaceutical

Completed

Schizophrenia Trial of Aripiprazole

Schizophrenia

Austria, United Kingdom, France, Spain, Sweden, Czech Republic, Denmark, Finland, Germany
GlaxoSmithKline

Completed

Pharmacokinetic and Pharmacodynamic (PK and PD) Study of Fluticasone Propionate and Salmeterol Combination Product Delivered in a Capsule-based Inhaler and in a Multi-dose Dry Powder Inhaler in Moderate Asthma Patients and Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Patients.

Asthma

Australia, New Zealand
Orion Corporation, Orion Pharma

Completed

To Confirm Equivalent Bronchodilator Efficacy of the Test Product Compared to the Reference Product (BUFODIL)

Asthma

Bulgaria
Nobelpharma

Completed

Efficacy and Safety, Long-Term Study of NPC-16 to Treat Dysmenorrhea

Dysmenorrhea
Lehigh Center for Clinical Research
Sunovion

Completed

Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder

Insomnia

United States
University of Maryland, Baltimore

Completed

Salmonella Conjugates CVD 1000: Study of Responses to Vaccination With Trivalent Invasive Salmonella Disease Vaccine

Risk Reduction

United States
Centro Universitario La Salle
Hospital de Clinicas de Porto Alegre

Completed

LDN and tDCS in Fibromyalgia

Fibromyalgia

Brazil

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