Search clinical trials for: Placebo oral tablet

Total 63637 results

Ultragenyx Pharmaceutical Inc

Terminated

Safety, Tolerability, and Pharmacokinetics of UX053 in Patients With Glycogen Storage Disease Type III (GSD III)

Glycogen Storage Disease Type III

United States, Spain, Italy
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder

Binge-Eating Disorder

United States
Axsome Therapeutics, Inc.

Enrolling by invitation

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

Alzheimer Disease | Agitation in Patients With Dementia of the Alzheimer's Type | Agitation, Psychomotor

United States, Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Phase Chronic Myelogenous Leukemia... and other conditions

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Breast Cancer

Japan, Poland, United States, Australia, Belgium, Brazil, Canada, China, Colombia, Costa Rica, France, Germany, Hungary, Ireland, Israel, Korea, Republic of, New Zealand, Portugal, Puerto Rico, Russian Federation, Spain, Taiwan, Ukr... and more
University of Pennsylvania

Completed

Stress and Inflammation in Late-Life Depression (S&I)

Depression | Inflammation

United States
Zealand University Hospital

Completed

Combined Intravenous Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Orthopaedic Surgery of the Foot and Ankle (ADJUNCT2)

Anesthesia, Local

Denmark
H. Lundbeck A/S
Takeda

Completed

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD)

Depressive Disorder, Major

Korea, Republic of, United States, Hungary, Poland, Spain, Serbia, Estonia, Bulgaria, Mexico, Russian Federation, Ukraine, Canada, Colombia, France, Germany, Israel, Italy, Latvia, South Africa
University of Washington
Bill and Melinda Gates Foundation

Terminated

Treatment for COVID-19 in High-Risk Adult Outpatients

COVID-19 | SARS-CoV-2

United States
YingHsuanTai

Withdrawn

Multi-Strategy Intervention for Anesthesia Care of Obese Patients A Factorial Randomized Controlled Trial

Obesity | Bariatric Surgery Candidate | Tracheal Intubation Morbidity | Nausea and Vomiting, Postoperative | Gastric Reflux | Hyperglycemia Drug Induced

Taiwan
Lebanese American University Medical Center

Active, not recruiting

Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC (MEDIC-LAUMC)

Covid19

Lebanon
Avanir Pharmaceuticals

Completed

Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease

Alzheimer's Disease | Agitation

United States
GlaxoSmithKline

Terminated

Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Australia, Argentina, France, Germany, Poland, Romania, Russian Federation, Spain, United States, Netherlands, Sweden, Korea, Republic of, Canada, United Kingdom, Italy, Mexico
Universitaire Ziekenhuizen KU Leuven
AstraZeneca

Active, not recruiting

Circulating Tumor DNA Guiding (Olaparib) Lynparza® Treatment in Ovarian Cancer (CLIO)

Ovarian Epithelial Cancer

Belgium
AstraZeneca

Completed

Two-part Pharmacokinetic and Pharmacodynamic Study of LAS190792 in Patients With Asthma and COPD

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
St. Petersburg State Pavlov Medical University

Terminated

Nivolumab With Chemotherapy in Refractory MDS

Myelodysplastic Syndromes

Russian Federation
Andrew Moshfeghi, MD, MBA
Case Western Reserve University

Withdrawn

Evaluation of Bromocriptine, Metoprolol and Tamsulosin in Eyes With Non-Central DME

Diabetic Macular Edema
Merck Sharp & Dohme LLC

Terminated

Efficacy and Safety Study of Fosaprepitant (MK-0517) Plus Ondansetron Versus Ondansetron Alone for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Participants (MK-0517-044)

Chemotherapy-induced Nausea and Vomiting
University Hospital, Basel, Switzerland

Completed

Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)

Substance-Related Disorders | Amphetamine-Related Disorders | Mood Disorder

Switzerland
Cady, Roger, M.D.
Avanir Pharmaceuticals

Completed

Nuedexta for the Prevention and Modification of Disease Progression in Episodic Migraine

Episodic Migraine

United States
Masonic Cancer Center, University of Minnesota

Terminated

Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Secondary Myelofibrosis

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
University of Turku
Yale University; University of Michigan; University of California, Irvine; University...

Completed

The Neural Mechanisms of Anesthesia and Human Consciousness (Part 6)

Unconsciousness | Anesthesia

Finland
Boehringer Ingelheim

Completed

Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC

Carcinoma, Non-Small-Cell Lung

Germany, Canada, United States, Hong Kong, Taiwan, Brazil, Korea, Republic of, Peru, Poland, Ukraine, Thailand, Argentina, Australia, New Zealand, Sweden, Hungary, Turkey, Serbia, Bosnia and Herzegovina, Chile, Colombia, Ecuador, Ir... and more
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Childhood Asthma Research and Education (CARE) Network Trial - Montelukast or Azithromycin for Reduction of Inhaled Corticosteroids in Childhood Asthma (MARS) (MARS)

Asthma

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Combined Effects of Alcohol and Caffeine

Alcohol or Other Drugs Effects

United States
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

Fixed or Self-Titrated Dosages of Sativex on Cannabis Users

Cannabis Dependence

Canada
Joseph Roscoe
National Cancer Institute (NCI)

Completed

Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical Trial

Nausea

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effects of Laropiprant on the Antiplatelet Effects of Clopidogrel and Aspirin in Combination (MK-0524A-114)(COMPLETED)

Primary Hypercholesterolemia | Mixed Hyperlipidemia
Nationwide Children's Hospital

Withdrawn

Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed or Refractory High-Risk NBL.

Neuroblastoma

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety and Efficacy of an Investigational Drug in HIV Infected Patients (0518-004)(COMPLETED)

HIV Infections | Acquired Immunodeficiency Syndrome
Pfizer

Completed

Assessment of the Analgesic Effects of PF-05089771 and Pregabalin in Healthy Volunteers Using Evoked Pain Endpoints

Healthy

Netherlands
Assistance Publique - Hôpitaux de Paris

Completed

Postoperative Vomiting in Children: Comparison Tri - Versus bi -Prophylaxis (VPOP2)

Postoperative Vomiting

France
Shaanxi Provincial People's Hospital
Chinese Medical Association

Unknown

The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery

Brain Injury | Cognitive Ability, General
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

ITT4 Intratesticular Hormonal Milieu in Man (ITT4) (ITT4)

Healthy Males

United States
Phillip Low
National Institute of Neurological Disorders and Stroke (NINDS); Vanderbilt... and other collaborators

Terminated

Study of Rifampicin in Multiple System Atrophy (MSA)

Multiple System Atrophy

United States
Alcon Research

Completed

Assessing the Efficacy of Maxidex® and Patanol® for the Treatment of Allergic Conjunctivitis

Allergic Conjunctivitis

United States
H. Lundbeck A/S

Completed

Randomised Placebo-controlled Duloxetine-referenced Efficacy and Safety Study of 2.5, 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder

Major Depressive Disorder
Scott and White Hospital & Clinic
Merck Sharp & Dohme LLC

Completed

Combination Antiemetic Regimen for Prevention of PONV in Breast Surgery Patients

Postoperative Nausea and Vomiting

United States
Otsuka Pharmaceutical Development & Commercialization...
Otsuka America Pharmaceutical

Completed

A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed Episode

Bipolar Disorder

United States, Puerto Rico
University of Virginia

Unknown

Study of Erythromycin in GER-Associated Apnea of the Newborn (SEGAN)

Apnea | Gastroesophageal Reflux | Bradycardia

United States
Baylor College of Medicine
National Institute on Drug Abuse (NIDA)

Completed

Modafinil - Escitalopram Study for Cocaine Dependence

Substance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine Addiction

United States
Genentech, Inc.

Completed

A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate (RUMBA)

Rheumatoid Arthritis
Pfizer

Completed

Study To Assess The Effect Of Gabapentin, Diphenhydramine And Morphine On Cold Pain In Healthy Male Volunteers

Healthy

Belgium
Centre for Addiction and Mental Health
Canadian Psychiatric Research Foundation

Completed

Antipsychotic Polypharmacy in Schizophrenia

Schizophrenia

Canada
Research Associates of New York, LLP

Completed

Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on the Healing of Stomach and Intestinal Ulcers (Lesions2)

Gastroduodenal Ulcer

United States
University of Nebraska

Recruiting

Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response

Rheumatoid Arthritis

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; University of Stellenbosch

Withdrawn

Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women

HIV Infection | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | FIGO Stage IIB Cervix Carcinoma | FIGO Stage III Cervix Carcinoma | FIGO Stage IVA Cervix Carcinoma

South Africa, Zimbabwe
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
S.LAB (SOLOWAYS)
NMSI DENTMASTER

Not yet recruiting

A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in Adults (ICLID)

Dental Pain

Russian Federation

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