Search clinical trials for: Placebo to Methotrexate

Total 61857 results

Clinica Santa Maria

Unknown

Atropine in Laparoscopic Gynaecological Surgery (ALGOS)

Laparoscopic Surgery | Gynecology

Chile
Centre for Addiction and Mental Health
Canadian Institutes of Health Research (CIHR)

Completed

D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement (HFDEX)

Pathological Gambling

Canada
Otsuka Pharmaceutical Development & Commercialization...

Completed

Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

Major Depressive Disorder

United States
National Cancer Institute (NCI)

Completed

SGN-30 and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Recurrent Adult Hodgkin Lymphoma | Adult Lymphocyte Depletion Hodgkin Lymphoma | Adult Lymphocyte Predominant Hodgkin Lymphoma | Adult Mixed Cellularity Hodgkin Lymphoma | Adult Nodular Sclerosis Hodgkin Lymphoma

United States
Zalicus

Terminated

CRx-102 Osteoarthritis Multicenter Evaluation Trial (COMET-1)

Knee Osteoarthritis

United States, Canada
GlaxoSmithKline
Bill and Melinda Gates Foundation; Wellcome Trust; Biomedical Advanced Research... and other collaborators

Recruiting

A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever

Salmonella Infections

Belgium, Malawi
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

Recurrent Breast Carcinoma | Metastatic Triple-Negative Breast Carcinoma | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7 | Metastatic Breast Carcinoma | Metastatic BRCA Hereditary Breast Carcinoma

United States, Puerto Rico
MGC Pharmaceuticals d.o.o

Active, not recruiting

Clinical Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19 (CimetrA)

Covid19 | Corona Virus Infection | SARS-CoV Infection

Israel
Neopharma Japan Co., Ltd.
Parexel

Withdrawn

A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria

Malaria
ViiV Healthcare
GlaxoSmithKline

Completed

Dose Ranging Study of GSK1265744 Plus Nucleoside Reverse Transcriptase Inhibitors for Induction of Human Immunodeficiency Virus-1 (HIV-1) Virologic Suppression Followed by Virologic Suppression Maintenance by GSK1265744 Plus Rilpivirine

HIV Infections | Infection, Human Immunodeficiency Virus

United States, Canada
Emory University
American Diabetes Association

Completed

Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2) (FFAADA)

Hypertension | Diabetes

United States
Masonic Cancer Center, University of Minnesota

Completed

Allogeneic Natural Killer (NK) Cells for Ovarian, Fallopian Tube, Peritoneal and Metastatic Breast Cancer

Breast Cancer | Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
Oriel Therapeutics

Completed

Clinical Efficacy Study of Salmeterol Xinafoate/Fluticasone Propionate in Asthma

Asthma

United States
Merck Sharp & Dohme LLC

Completed

Aprepitant for the Prevention of Chemotherapy Induced Nausea and Vomiting (CINV)(0869-130)(COMPLETED)

Chemotherapy-Induced Nausea and Vomiting
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies

Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma and other conditions

United States
Joseph Hazelton

Completed

A Double-Blind, Randomized, Active- and Placebo-Controlled, Multiple-Dose Multi-Center Phase 3 Study of the Safety and Efficacy of CL-108 in the Treatment of Moderate to Severe Acute Pain and Opioid-Induced Nausea and Vomiting (OINV)

Pain | Nausea | Vomiting

United States
Hackensack Meridian Health
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer

Breast Cancer

United States
Sunovion

Completed

A Randomized, Placebo-Controlled, Two-Period, Crossover Study to Evaluate the Effect of Lurasidone HCl on Oral Contraceptive Pharmacokinetics in Healthy Female Subjects (OC-DDI)

Pharmacokinetics

United States
Ullevaal University Hospital
University of Oslo

Completed

Analgesic Effect of Ibuprofen, Paracetamol (Acetaminophen), and Paracetamol (Acetaminophen) Plus Codeine on Acute Pain

Surgery

Norway
ALK-Abelló A/S

Completed

Efficacy of SLITone in House Dust Mite Allergic Patients

Allergy

Spain
Arab Contractors Medical Centre

Not yet recruiting

Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced Cardiomyopathy (BASiC-CIC)

Chemotherapy Induced Systolic Dysfunction

Egypt
University of Rochester NCORP Research Base
National Cancer Institute (NCI)

Recruiting

High-Dose Vitamin D Supplementation for ADT-Induced Bone Loss in Older Prostate Cancer Patients

Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8

United States
National Cancer Institute (NCI)

Recruiting

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Pancreatic Acinar Cell Carcinoma | Pancreatic Adenosquamous Carcinoma | Pancreatic Squamous Cell Carcinoma | Resectable Pancreatic Acinar Cell Carcinoma | Resectable Pancreatic Adenocarcinoma | Resectable Pancreatic Adenosquamous Carcinoma | Resectable Pancreatic Carcinoma

United States
MEDA Pharma GmbH & Co. KG

Completed

Azelastine Allergen Chamber - Onset of Action Study

Seasonal Allergic Rhinitis

Canada
Orient Pharma Co., Ltd.

Completed

A Relative Efficacy and Safety Study of OC Oral Solution for Sialorrhoea in Patients With Parkinson's Disease

Sialorrhoea

United States
Pakistan Institute of Medical Sciences
Riphah International University

Completed

COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA (EDCLAS)

Sciatica | Sciatica Acute

Pakistan
GlaxoSmithKline

Terminated

Evaluation of an Anti-cancer Immunotherapy Combined With Standard Neoadjuvant Treatment in Patients With WT1-positive Primary Invasive Breast Cancer (INDUCT)

Neoplasms, Breast

United States, Belgium, United Kingdom, Germany, Russian Federation, Italy, France
Ain Shams University

Completed

Prophylactic Mirtazapine or Dexamethasone for Post-spinal Anesthesia Shivering

Shivering

Egypt
University of California, Davis
Society of Family Planning

Completed

Gabapentin for Pain Control After Osmotic Dilator Insertion and Prior to D&E Procedure: a Randomized Controlled Trial (GABA)

Pain | Abortion, Induced | Cervical Preparation

United States
National University Hospital, Singapore

Completed

Outcomes Of Perioperative Pregabalin On Total Knee Arthroplasty

Pain, Postoperative
St George Hospital, Australia
St George & Sutherland Medical Research Foundation

Unknown

A Comparative Effectiveness Randomised Placebo Controlled Pilot Trial of the Management of Acute Lumbar Radicular Pain (SCIATICA)

Acute Sciatica

Australia
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Completed

Medications for Stopping Cocaine Dependence and Preventing Relapse

Cocaine-Related Disorders | Cocaine Abuse

United States
Tufts Medical Center
National Institute of Mental Health (NIMH)

Completed

Treatment for Bipolar Depression: Acute & Prophylactic Efficacy With Citalopram

Bipolar Disorder | Bipolar Depression

United States
Celgene Corporation

Completed

A Study to Compare MPR With MP in Newly Diagnosed Multiple Myeloma Subjects 65 Years Old or Older.

Newly Diagnosed Multiple Myeloma

Spain, Netherlands, Austria, Australia, Italy, Russian Federation, United Kingdom, Israel, Belgium, Greece, Germany, Poland, Turkey, France, Denmark, Czech Republic, Belarus, Georgia, Ireland, Sweden, Switzerland, Ukraine
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Research Study to Determine if an Experimental Agent, LLME Can Decrease the Incidence and Severity of Graft-Versus-Host-Disease (GVHD) Following Blood (Hematopoietic) Stem Cell Transplantation

Hematologic Malignancies

United States
Northwestern University
National Institutes of Health (NIH); National Institute of Dental and Craniofacial...

Withdrawn

Efficacy of Co-administration of an NSAID With a Dopamine Agonist In Healthy Subjects

Acute Pain
Janssen Scientific Affairs, LLC

Completed

A Study to Evaluate Dara-CyBorD in Previously Untreated and Relapsed Subjects With Multiple Myeloma

Multiple Myeloma

United States
University of California, San Francisco
Genentech, Inc.

Terminated

Chemotherapy & Erlotinib in Treating Patients w/ Esophageal or Gastroesophageal Cancer That Cannot Be Removed by Surgery

Esophageal Cancer

United States
IRCCS Burlo Garofolo

Completed

Sublingual Analgesia for Acute Abdominal Pain in Children

Abdominal Pain

Italy
AstraZeneca

Completed

ATAC - Bone Density Sub-Protocol

Bone Density
AstraZeneca

Completed

Harmonizing RCT-Duplicate Emulations In A Real World Replication Program (HARRP) (HARRP)

Type 2 Diabetes Mellitus

Sweden
AstraZeneca

Completed

ABCSG 8 - Adjuvant Treatment in Patients With Hormone Receptor-positive Breast Cancer With Good to Moderate Differentiation.

Breast Cancer

Austria
AstraZeneca

Completed

ATAC - Pharmacokinetics (PK) Sub-Protocol

Breast Cancer
National Cancer Institute (NCI)

Completed

Pomalidomide After Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Myelomonocytic Leukemia-2

United States
Purdue Pharma LP

Completed

The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) at Doses up to 80 Micrograms/Hour (mcg/hr) and Naltrexone on Electrocardiogram (ECG) Intervals in Healthy Volunteers

ECG Effects

United States
Centre Hospitalier Universitaire Vaudois

Active, not recruiting

TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in Metastatic Melanoma (mMEL)

Metastatic Melanoma

Switzerland
University of Aarhus
Lundbeck Foundation

Completed

Use of Local Infiltration Analgesia Following Total Hip Arthroplasty

Pain | Pain, Postoperative

Denmark
Millennium Pharmaceuticals, Inc.

Completed

Study of Oral Ixazomib in Combination With Melphalan and Prednisone in Participants With Newly Diagnosed Multiple Myeloma

Multiple Myeloma

United Kingdom, Spain, Canada, United States, Czechia
Pfizer

Completed

Exemestane As Treatment In Adjuvant For Post-Menopausal Patients With Non-Metastatic Breast Cancer (TEAM)

Breast Neoplasms

France
Martin Huelsmann

Recruiting

NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients

Heart Diseases | Diabetes Mellitus, Type 2

New Zealand, Austria, Netherlands, Spain, United Kingdom

Search clinical trials for: Placebo to Methotrexate

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