Search clinical trials for: Placebo vehicle solution

Total 69865 results

Merck Sharp & Dohme LLC

Terminated

A Double-masked, Randomized, Placebo-controlled,Pilot Study of Diquafosol Tetrasodium in Subjects Following Photorefractive Keratectomy (PRK)

Photorefractive Keratectomy
Université de Sherbrooke
Canadian Institutes of Health Research (CIHR); Centre de recherche du Centre... and other collaborators

Not yet recruiting

Effect of CANnabidiol on Anxiety and GABAergic Function in Individuals With Fragile-X Syndrome (CANAX)

Fragile X Syndrome
GlycaNova AS
OPIS USA

Recruiting

The Effect of LentinexHP® on Quality of Life in Stage IV Colorectal Cancer

Change in Mood | Change in Personality

Bulgaria
Organ, Tissue, Regeneration, Repair and Replacement

Recruiting

Post-surgical Scars After the Use of CACIPLIQ20 (MATRISCAR)

Scars

France
Centre Hospitalier Universitaire Vaudois

Recruiting

Exploring the Effect of Lactate Administration After Ischemic Stroke on Brain Metabolism (LacAVC)

Stroke, Acute

Switzerland
Novartis Pharmaceuticals

Active, not recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia (ORION-13)

Familial Hypercholesterolemia - Homozygous

Greece, Lebanon, Turkey, France, Canada, Malaysia, Netherlands, United States
The Medicines Company

Completed

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol (ORION-10)

Elevated Cholesterol | ASCVD

United States
DUSA Pharmaceuticals, Inc.

Completed

Twelve Month Follow-Up of CP0108

Actinic Keratosis

United States
Novan, Inc.

Completed

P2 Multi-center Study of SB204 Gel in the Treatment of Acne Vulgaris

Acne Vulgaris

United States
Richard W Yee, MD
Novartis Pharmaceuticals

Recruiting

The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Disease

Graft-versus-host-disease | Ocular Graft-versus-host Disease

United States
Ocuphire Pharma, Inc.

Completed

Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia

Presbyopia

United States
Sun Pharmaceutical Industries Limited

Completed

Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca

Keratoconjunctivitis Sicca | Dry Eye Disease

United States
Aerie Pharmaceuticals

Completed

A Study of AR-12286 in Patient With Elevated Intraocular Pressure (IOP)

Elevated Intraocular Pressure

United States
Aldeyra Therapeutics, Inc.

Completed

A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Aldeyra Therapeutics, Inc.

Completed

A Safety and Activity Study of NS2 in Subjects With Allergic Conjunctivitis

Allergic Conjunctivitis | Seasonal Allergies

Canada
Artery Therapeutics, Inc.
National Institute on Aging (NIA)

Recruiting

Safety and Pharmacokinetics of Single Ascending Doses and Multiple Ascending Doses of CS6253 in Healthy Volunteers

Alzheimer's Disease

Spain
Novartis Pharmaceuticals

Active, not recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia (ORION-16)

Familial Hypercholesterolemia - Heterozygous

United States, Germany, South Africa, Greece, Italy, Czechia, Taiwan, Slovakia, Turkey, France, Russian Federation, Canada, Spain, Jordan, Switzerland, Hungary, Poland, Netherlands, Norway, United Kingdom, Lebanon, Argentina, Brazil, ... and more
Vicore Pharma AB

Completed

First-in-human Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of C106 in Healthy Subjects

Idiopathic Pulmonary Fibrosis | Pulmonary Hypertension | Tolerance | Safety Issues

Sweden
Jazz Pharmaceuticals

Completed

A Multicenter Study of the Efficacy and Safety of JZP-258 in the Treatment of Idiopathic Hypersomnia (IH) With an Open-label Safety Extension

Idiopathic Hypersomnia

France, Spain, United States, Belgium, United Kingdom, Poland, Czechia, Finland
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories...
Attikon Hospital

Terminated

Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection (Thy-Support)

Covid-19 | Pulmonary Infection

Greece
Spyryx Biosciences, Inc.

Completed

An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis ((HOPE-1))

Cystic Fibrosis

United Kingdom, Canada, France, Italy, Portugal
Centers for Disease Control and Prevention, China
Beijing Ditan Hospital; National Institutes for Food and Drug Control, China

Unknown

Clinical Trial of Recombinant Adenovirus Type 5 AIDS Vaccine

Acquired Immunodeficiency Syndrome

China
Bausch & Lomb Incorporated

Completed

Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage

Diabetic Retinopathy | Vitreous Hemorrhage

Spain, Australia, United Kingdom, Brazil, Hungary, Italy, Netherlands, Poland, South Africa
Maastricht University Medical Center

Completed

Microvascular Dilatation After Endogenous Induced Hyperinsulinemia

Hypertension | Obesity

Netherlands
LianBio LLC

Completed

Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA Study

Blepharitis

China
Oculis
ORA, Inc.

Active, not recruiting

Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease (RELIEF)

Dry Eye Disease

United States
Maruho North America Inc.

Completed

Skin Safety Study to Evaluate the Irritation Potential in Healthy Volunteers

Healthy Volunteers

United States
C.T. Development America, Inc.

Completed

Evaluation of the Onset and Duration of Action of RX-10045 in Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Faes Farma, S.A.
ORA, Inc.

Completed

A Study Evaluating Bilastine Ophthalmic Solution 0.6% in the Conjunctival Allergen Challenge (Ora-CAC®) Model.

Allergic Conjunctivitis

United States
Aires Pharmaceuticals, Inc.

Completed

Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers (AIR001-CS02)

Pulmonary Arterial Hypertension

United States
United Therapeutics

Terminated

A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD) (PERFECT)

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

United States, Israel, Argentina, Puerto Rico
GlaxoSmithKline
Clinical Unit at Cambridge (Addenbrooks)

Completed

A Safety and Tolerability Study of GSK2982772, in Single (in Both Fed and Fasted States) and Repeat Oral Doses in Healthy Male Subjects

Inflammatory Bowel Diseases

United Kingdom
Ocular Therapeutix, Inc.

Completed

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Ocular Hypertension | Open Angle Glaucoma

United States
Tamir Biotechnology, Inc.

Completed

Safety and Efficacy Study of Topical Ranpirnase to Treat Genital Warts (HPV)

Sexually Transmitted Diseases | Papillomavirus Infections | Condylomata Acuminata

Bolivia
Sun Pharma Advanced Research Company Limited

Completed

Effect of Different Concentrations of SPARC1102 on Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Allergan

Completed

Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia

Presbyopia

United States
Topivert Pharma Ltd

Completed

Study of TOP1630 for Dry Eye Syndrome (THEIA-1)

Dry Eye Syndrome

United States
Alcon Research

Completed

AL-54478 Proof of Concept Study

Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)
Allergan

Terminated

A Study of the Safety and Efficacy of Bimatoprost Ophthalmic Solution in Paediatric Patients With Glaucoma

Glaucoma

United Kingdom, Taiwan, Korea, Republic of, United States, Italy, Philippines, France
Novan, Inc.
Premier Research Group plc

Completed

A Study to Evaluate the Safety and Efficacy of SB206 in Subjects With Molluscum Contagiosum

Molluscum Contagiosum

United States
Novan, Inc.
PPD

Completed

Topical NVN1000 for the Treatment of External Genital and Perianal Warts

Genital Warts | Perianal Warts

United States
AJU Pharm Co., Ltd.
GL Pharm Tech Corporation

Recruiting

Efficacy and Safety of AJU-S56 5% in Dry Eye Syndrome Patients

Dry Eye Syndromes

Korea, Republic of
Dr. Bradley Welling
United States Department of Defense

Completed

Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations

Tympanic Membrane Perforation

United States
ASIT Biotech S.A.

Unknown

Clinical Efficacy and Safety of Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis

Hay Fever
Octapharma

Terminated

Safety and Efficacy Study of Three Different Dosages of NewGam in Patients With CIDP (POINT)

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Unilever R&D

Completed

The Effect of a Natural Extract on Glucose Fluxes After Consumption of a Wheat Product

Healthy

Netherlands
NYU Langone Health
Naurex, Inc, an affiliate of Allergan plc

Withdrawn

NRX-1074 in Early Course Schizophrenia

Schizophrenia

United States
St. Justine's Hospital
Canadian Association of Emergency Physicians

Completed

Effect on Pain of Oral Sucrose Versus Placebo in Children 1 to 3 Months Old Needing Venipuncture

Pain

Canada
St. Justine's Hospital

Completed

Trial of an Oral Sucrose Solution Versus Placebo in Children 1 to 3 Months Old Needing Bladder Catheterization

Pain

Canada
Ospedale Misericordia e Dolce

Completed

Hydration and Contrast-Induced Nephropathy in Primary Angioplasty

Contrast Induced Nephropathy

Italy

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