Search clinical trials for: Protease Inhibitors

Total 64148 results

Bristol-Myers Squibb

Completed

Pharmacokinetics and Pharmacodynamics of Apixaban in Subjects on Hemodialysis

End Stage Renal Disease

United States
Imperial College London
British Heart Foundation

Completed

Investigation of Leukocyte Trafficking Into Skin Blisters During Cardiopulmonary Bypass

Angina Pectoris | Ischemic Heart Disease

United Kingdom
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Respiratory Distress Syndrome After Cardiac Surgery :a Single Centre Random Control Trial.

Cardiac Disease
Nanfang Hospital of Southern Medical University
Guangdong No.2 Provincial People's Hospital; Foshan Hospital of Traditional... and other collaborators

Enrolling by invitation

Effect of Early Treatment With Sivelestat Sodium in ARDS Patients (siv-ARDS)

Inflammatory Response | ARDS

China
Children's Hospital Los Angeles
Baylor College of Medicine; Children's Hospital of Philadelphia; Children's Hospital... and other collaborators

Completed

The UNBLOCK Study: Utilization of Bivalirudin On Clots in Kids (UNBLOCK)

Deep Venous Thrombosis

United States
Grifols Therapeutics LLC

Completed

Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults (ChAMP)

Alpha 1-Antitrypsin Deficiency

United States
Peking Union Medical College Hospital
Xiangya Hospital of Central South University; Ruijin Hospital; China-Japan Friendship...

Recruiting

The Study of Monitoring and Dosing Guidance of Direct Oral Anticoagulants Based on Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics

Pulmonary Embolism

China
University of Vermont Medical Center
Dartmouth-Hitchcock Medical Center; MaineHealth

Not yet recruiting

Venous Thromboembolism Prevention in Outpatients With Glioma (VTE-POG)

Glioblastoma | Astrocytoma | Venous Thromboembolism
Chinese University of Hong Kong
Prince of Wales Hospital, Shatin, Hong Kong

Recruiting

Pharmacokinetics of Apixaban in Peritoneal Dialysis

Atrial Fibrillation

Hong Kong
Seoul National University Hospital

Not yet recruiting

Camostat Mesylate for Protein-losing Enteropathy After Fontan Operation

Fontan Operation | Protein-Losing Enteropathy | Camostat Mesylate
China National Center for Cardiovascular Diseases

Recruiting

An Exploratory stuDy of effectIveneSs and Safety of rivarOxaban in Patients With Left VEntricular Thrombus (R-DISSOLVE) (R-DISSOLVE)

Ventricular Mural Thrombosis

China
General Hospital of Shenyang Military Region

Recruiting

Early Rivaroxaban for Acute Ischemic Stroke or TIA Patients With Atrial Fibrillation (ERSAF)

Cerebral Infarction | TIA

China
Stanford University

Completed

COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Master Protocol

Covid19

United States
Stanford University

Terminated

COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Camostat Sub-Protocol (COPPS)

Covid19

United States
Seoul National University Hospital

Active, not recruiting

Efficacy and Safety of Apixaban in Korean Frail Atrial Fibrillation Patient

Atrial Fibrillation

Korea, Republic of
Assistance Publique - Hôpitaux de Paris

Terminated

CAMOVID : Evaluation of Efficacy and Safety of Camostat Mesylate for the Treatment of SARS-CoV-2 Infection - COVID-19 in Ambulatory Adult Patients (CAMOVID)

Covid19

France
University Hospital Inselspital, Berne

Terminated

Comparison of Antithrombotic Treatments After Aortic Valve Replacement. Rivaroxaban: A New Antithrombotic Treatment for Patients With Mechanical Prosthetic Aortic Heart Valve. (CATHAR)

Aortic Valve Disease | Anticoagulants | Heart Valve Prosthesis Implantation

Switzerland
Bristol-Myers Squibb

Completed

Apixaban in the Prevention of Stroke and Systemic Embolism in Patients With Atrial Fibrillation in Real-Life Setting in France

Anticoagulation

France
Janssen Scientific Affairs, LLC
Bayer

Completed

Pharmacokinetics Study of Oral Rivaroxaban in Healthy Participants

Pharmacokinetics | Healthy Participants | Bioavailability

United States
Yonsei University

Completed

Effect of Ulinastatin on Postoperative Renal Function in Patients Undergoing Robot-assisted Laparoscopic Partial Nephrectomy

Renal Mass

Korea, Republic of
Pfizer

Completed

Food Effect Study For Apixaban Commercial Image Tablets

Healthy

Singapore
Texas Biotechnology Corporation

Completed

Pharmacokinetics/Pharmacodynamics of Argatroban Injection in End-Stage Renal Disease Patients Undergoing Hemodialysis

Kidney Failure, Chronic | Renal Disease, End-Stage

United States
Rabin Medical Center
Kamada, Ltd.

Completed

Long Term Treatment Effect of the Safety, Tolerability and Efficacy of AAT in Type 1 Diabetes (AAT Extension)

Type 1 Diabetes | Beta Cell Preservation

Israel
Virginia Commonwealth University

Completed

Alpha-1 Anti-Trypsin (AAT) Treatment in Acute Myocardial Infarction (VCU-Alpha1RT)

Acute Myocardial Infarction

United States
Baxalta now part of Shire
Arriva Pharmaceuticals, Inc.

Completed

Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency

Alpha1-antitrypsin Deficiency

United States
Southeast University, China

Recruiting

Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis

ARDS

China
Octapharma

Recruiting

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery

Congenital Antithrombin Deficiency

Spain, Italy, United States, Serbia, France, Hungary, Austria, Germany, United Kingdom, Israel
Brigham and Women's Hospital

Completed

Replication of the RECOVER-II Anticoagulant Trial in Healthcare Claims Data

Venous Thromboembolism

United States
Ural State Medical University
Boehringer Ingelheim

Unknown

Evaluation of Abbreviated Versus Conventional Course of Dabigatran Etexilate Before Electric Cardioversion in Patients With Atrial Fibrillation (RE-SOUND Study) (RE-SOUND)

Atrial Fibrillation

Russian Federation
Boehringer Ingelheim

Completed

Safety and Tolerability of Dabigatran Etexilate in Adolescents

Venous Thromboembolism

Canada
Boehringer Ingelheim

Completed

Bioequivalence of Two Different Capsule Types of Dabigatran

Healthy

Germany
Boehringer Ingelheim

Terminated

Long-term, Open-label Follow-up Treatment of Patients With A-fib Who Have Been Previously Treated With BIBR 1048

Stroke | Atrial Fibrillation

United States, Denmark, Netherlands, Sweden
Huashan Hospital

Not yet recruiting

Clinical Efficacy of Ulinastatin for Treatment of Sepsis With Systemic Inflammatory Response Syndrome (CURE-SepSIRS)

Sepsis

China
China-Japan Friendship Hospital

Not yet recruiting

Effectiveness and Safety of Rivaroxaban Used in Extended Anticoagulation for Pulmonary Embolism Patients

Pulmonary Embolism
Erasmus Medical Center
Daiichi Sankyo, Inc.

Recruiting

Rotterdam EDOXaban Leaflet Evaluation in Patients After Transcatheter Aortic Valve Implantation (REDOX-TAVI)

Aortic Valve Stenosis

Netherlands
Pfizer

Completed

Effectiveness And Safety Of Oral Anticoagulants Among Obese Patients With Non-Valvular A-Fib In VA Patients With Medicare

Obesity | Atrial Fibrillation | Anticoagulants

United States
Portola Pharmaceuticals

Completed

The Effect o f Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Betrixiban, an Oral FXa Antagonist

Hepatic Impairment

United States
New York Medical College

Completed

Oral Anticoagulant Apixaban for Treatment of Venous Thromboembolism (VTE)

Venous Thromboembolism

United States
Assistance Publique - Hôpitaux de Paris

Completed

Xarelto Versus no Treatment for the Prevention of Recurrent Thrombosis in Patients With Chronic Portal Vein Thrombosis. (RIPORT)

Deep Vein Thrombosis | Chronic Portal Vein Thrombosis

France
Fadoi Foundation, Italy
University Of Perugia

Completed

Rivaroxaban or Placebo for Extended Antithrombotic Prophylaxis After Laparoscopic Surgery for Colorectal Cancer. (PRO-LAPSII)

Prevention of Venous Thromboembolism

Italy
Thomas Jefferson University

Completed

Pharmacokinetics of Apixaban in Patients Undergoing Pancreaticoduodenectomy (PAP-UP)

Pancreas Cancer | Pulmonary Embolism | DVT

United States
Johns Hopkins University

Completed

Apixaban Pharmacokinetics in Bariatric Patients (APB) (APB)

Obesity | Bariatric Surgery

United States
Samsung Medical Center
Bayer

Unknown

Rivaroxaban in Elderly NVAF Patients With or Without Renal Impairment (XAIENT)

Renal Insufficiency | Atrial Fibrillation | Elderly | Rivaroxaban

Korea, Republic of
University of Alberta

Completed

Eliquis Acute Stroke Safety Evaluation (EASSE)

Ischemic Stroke | Atrial Fibrillation | Transient Ischemic Attack

Canada
Daiichi Sankyo, Inc.

Completed

Edoxaban Management in Diagnostic and Therapeutic Procedures (EMIT-AF/VTE)

Atrial Fibrillation | Venous Thromboembolism
Daiichi Sankyo, Inc.

Completed

Edoxaban Treatment in Routine Clinical Practice in Patients With Venous Thromboembolism in Korea and Taiwan (ETNA-VTE-KOR-TWN)

Venous Thromboembolism

Taiwan, Korea, Republic of
Astellas Pharma Inc

Completed

A Study to Compare the Pharmacokinetics of YM150 Formulation-A and Formulation-B

Healthy Volunteer | Pharmacokinetics of YM150

Japan
Nanjing Medical University
Beijing Anzhen Hospital

Not yet recruiting

Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Sivelestat) VI

Systemic Inflammatory Response Syndrome | Aortic Dissection

China
Brigham and Women's Hospital

Completed

Replication of the RELY Anticoagulant Trial in Healthcare Claims Data

Atrial Fibrillation

United States
University of Alberta
Boehringer Ingelheim

Completed

Canadian Pradaxa Acute Stroke Safety Study (CPASS)

Stroke | Ischemic Attack, Transient

Canada

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