Search clinical trials for: Protease Inhibitors

Total 64611 results

Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
China National Center for Cardiovascular Diseases

Not yet recruiting

Low-dose Versus Standard-dose Rivaroxaban in Elderly Patients With Atrial Fibrillation

Stroke | Atrial Fibrillation | Major Adverse Cardiac Events | Anticoagulant Adverse Reaction
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); Amgen

Not yet recruiting

Mechanistic Clinical Trial of PCSK9 Inhibition for AAA

Abdominal Aortic Aneurysm
Kevin H.M. Kuo, MD, MSc, FRCPC

Recruiting

THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS) (THIS)

Sickle Cell Disease | Venous Thromboembolism | Central Venous Catheter Thrombosis

Canada
University of Texas at Austin
University of Kansas

Not yet recruiting

Restart TICrH Alpha Pilot Protocol, Restarting DOACs After Traumatic Intracranial Hemorrhage

Anticoagulants; Increased
McMaster University

Recruiting

Postoperative Extended Venous Thromboprophylaxis in Inflammatory Bowel Disease (EXPAND)

Crohn Disease | Ulcerative Colitis | Venous Thromboembolism | Colorectal Disorders | Pulmonary Embolism | IBD

Canada
Brigham and Women's Hospital

Active, not recruiting

Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism (HI-PRO)

Deep Vein Thrombosis | Venous Thromboembolism | Pulmonary Embolism

United States
Montreal Heart Institute
Servier

Active, not recruiting

Canadian EdoxAban(Lixiana®) Registry in Patients With ATrial Fibrillation/Flutter With Confirmed ValvUlar HeaRt DiseasE (CAPTURE)

Valvular Heart Disease | Atrial Fibrillation and Flutter

Canada
Inova Health Care Services

Terminated

Antiplatelet Effects of Evolocumab in Patients With Peripheral Arterial Disease

Peripheral Arterial Disease

United States
Bristol-Myers Squibb

Completed

Real-World Comparative Observational Study in Non-Valvular Atrial Fibrillation Patients Using Oral Anticoagulants

Atrial Fibrillation
Grifols Therapeutics LLC
Grifols Japan K.K.

Completed

Safety and Pharmacokinetics of Alpha-1 MP (Alpha1-proteinase Inhibitor (Human), Modified Process) in Participants With Alpha1-Antitrypsin Deficiency

Alpha1-Antitrypsin Deficiency

Japan
AIO-Studien-gGmbH
Bayer; Charite University, Berlin, Germany

Terminated

Rivaroxaban in the Treatment of Venous Thromboembolism (VTE) in Cancer Patients

Cancer | Venous Thromboembolism

Germany
Perosphere Pharmaceuticals Inc, a wholly owned...

Completed

Phase 2 Study of Apixaban Reversal by Ciraparantag as Measured by WBCT

Healthy

United States
Bayer

Terminated

Effect of Aprotinin on Transfusion Requirements in Patients Undergoing Elective Spinal Fusion Surgery

Blood Loss, Surgical | Postoperative Hemorrhage

Spain, Germany, Canada
Bristol-Myers Squibb
Pfizer

Completed

Phase 1 Oral Solution and Crushed Tablet Relative Bioavailability Study of Apixaban When Administered Through a Nasogastric Tube in Healthy Subjects

Healthy Subjects

United States
Abramson Cancer Center of the University of Pennsylvania

Terminated

Proton Beam Radiation With Concurrent Chemotherapy and Nelfinavir for Inoperable Stage III Non Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

United States
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Completed

Optimization of Darunavir Therapy and Dosage Recommendations

Human Immunodeficiency Virus I Infection

Belgium
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C202: A Study of Safety, Efficacy, and Tolerability of TMC114 and Low Dose Ritonavir in HIV-1 Infected Patients

HIV Infections

United States, Argentina
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors

Nasopharyngeal Cancer | Gastric Cancer | Hodgkin Lymphoma | Castleman Disease | Non-Hodgkin Lymphoma | Kaposi Sarcoma | EBV

United States
Brigham and Women's Hospital
National Institutes of Health (NIH)

Completed

A Pilot Study of Moderate Hyperbilirubinemia in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Tibotec Pharmaceuticals, Ireland

Completed

An Open Label Trial of TMC114/RTV in HIV-1 Infected, Treatment-experienced Subjects.

HIV Infection

United States, Australia, France, United Kingdom, Germany, Spain, Belgium, Portugal, Canada, Argentina, Brazil, Austria, Hungary
Fundacion SEIMC-GESIDA
ViiV Healthcare

Completed

HCV Evolution in HIV/HCV (Genotype 1) Coinfected Patients Treated With Fosamprenavir (FOSTER-C)

HCV Coinfection | Chronic HIV Infection

Spain
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-TiDP3-C181: Study to Assess the Pharmacokinetics of Darunavir (DRV) With Different Doses of Ritonavir in Healthy Volunteers.

HIV | AIDS
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C201: A Study to Determine the Antiviral Activity of TMC114 in Patients With Multiple Protease Inhibitor (PI) Resistant Human Immunodeficiency Virus (HIV) Strains

HIV Infections
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Mycobacterium Avium Complex Disease (MAC)

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Agouron Pharmaceuticals

Completed

A Study of Viracept in HIV-Positive Women

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3

HIV Infections | Sarcoma, Kaposi

United States
Agouron Pharmaceuticals

Completed

Phase I Study of Safety, Tolerability, and Pharmacokinetics of Viracept in HIV-1 Infected Children and Exposed Infants

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Viracept Expanded Access Program

HIV Infections

United States
Mayo Clinic

Terminated

Treating Acute Pancreatitis With Dabigatran, a Pilot Study

Acute Pancreatitis

United States
Hamad Medical Corporation

Unknown

Anticoagulation in Patients Suffering From COVID-19 Disease The ANTI-CO Trial

Anticoagulation in COVID-19 ARDS

Qatar
Assiut University

Unknown

Postoperative Acute Kidney Injury in Patients Undergoing Prolonged Neurosurgical Operations

Postoperative Acute Kidney Injury
University of British Columbia
Smith & Nephew, Inc.

Completed

A Trial Comparing Circumferential Casting Versus Splinting in Displaced Colles' Fractures

Colles' Fracture

Canada
Hoffmann-La Roche

Completed

A Study of Ritonavir-Boosted Invirase (Saquinavir) in Treatment-Naïve HIV-1 Infected Patients

HIV Infections

United Kingdom
Northwestern University

Suspended

Study To antagOnize Plasminogen Activator Inhibitor-1 in Severe COVID-19

Covid19

United States
Assiut University

Not yet recruiting

TF, TFPI and Plasmin as Novel Bio-markers in Early Diagnosis of Lupus Nephritis

Lupus Nephritis
University of British Columbia
Queensland Children's Hospital, South Brisbane

Recruiting

Management of Type 1 Supracondylar Humeral Fractures

Trauma | Elbow Fracture

Canada, Australia
Far Eastern Memorial Hospital

Completed

Biobased Polyester Versus Synthetic Fiberglass Casts for Treating Stable Upper Limb Fractures in Children

Upper Limb Fracture

Taiwan
Georg Nickenig
Boehringer Ingelheim

Completed

Prevention of Silent Cerebral Thromboembolism by Oral Anticoagulation With Dabigatran After Pulmonary Vein Isolation for Atrial Fibrillation (ODIn-AF)

Atrial Fibrillation | Oral Anticoagulation | Cardioembolic Events

Germany
Assiut University

Unknown

Cystatin c and Beta 2 Microglobulin in Thalassemic Children.

Blood Disease
La Jolla Pharmaceutical Company

Completed

A Study of LJPC-501 in Pediatric Patients With Hypotension

Sepsis | Catecholamine-resistant Hypotension (CRH) | Distributive Shock | High Output Shock

United States
Yokohama City University Medical Center

Completed

Effect of Neutrophil Elastase Inhibitor on Lung Injury After Esophagectomy (NEIE)

Esophageal Cancer

Japan
Nanjing First Hospital, Nanjing Medical University
National Natural Science Foundation of China; Nanjing Medical University

Recruiting

PCSK 9 Inhibitor Added to High-Intensity Statin Therapy to Prevent Cardiovascular Events in Patients With ACS After PCI (SHAWN)

Hyperlipidemias | Acute Coronary Syndrome | Percutaneous Coronary Intervention | Cardiovascular Events

China
Medical College of Wisconsin

Not yet recruiting

Lexiva for the Treatment of LPR

Laryngopharyngeal Reflux

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

A Trial of the Protease Inhibitor Nelfinavir and Concurrent Radiation and Temozolomide in Patients With WHO Grade IV Glioma

Glioma

United States
University of Colorado, Denver
Omni Bio Pharmaceutical, Inc.

Completed

The Effects of Alpha-1 Antitrypsin (AAT) on the Progression of Type 1 Diabetes

Diabetes | Type 1 Diabetes

United States
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Venous Thromboembolism... and other collaborators

Not yet recruiting

VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy (PREVENT-GU)

Venous Thromboembolism | Urologic Cancer
Brigham and Women's Hospital

Recruiting

The Impact of Pcsk-9 Inhibition on PET CFR in Patients at High CV Risk (EMPOWER)

Stable Coronary Disease

United States
University of Nebraska
Amgen

Completed

Impact of Evolocumab in Cardiac Transplant Patients With CAV

Heart Transplant

United States
Mitsubishi Tanabe Pharma GmbH

Completed

Safety of Argatroban Infusion in Conduction Disturbances (SAICoDis)

Stable Coronary Artery Disease (CAD) | Unstable Angina (Troponin Negative)

Germany

Search clinical trials for: Protease Inhibitors

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