Search clinical trials for: Proteasome Inhibitors

Total 64220 results

Yale University
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

Pilot Study of a Raltegravir Based NRTI Sparing Regimen

HIV Infections | Human Immunodeficiency Virus | AIDS | Acquired Immune Deficiency Syndrome

United States
The Third Xiangya Hospital of Central South University
Xiangya Hospital of Central South University

Unknown

Testing of HIV Protease Inhibitors to Suppress Inflammation and Improve Cardio Pulmonary Hemodynamics in Subjects With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

China
Boehringer Ingelheim

Completed

Pharmacokinetic Interaction Study of Steady-state Tipranavir/Ritonavir (TPV/r) With Single-dose Valaciclovir (VAL) in Healthy Volunteers

Healthy
Hospitales Universitarios Virgen del Rocío

Completed

Darunavir Levels, Virological Efficacy, Proviral ADN and Resistances in Patients on Darunavir/Ritonavir Monotherapy (MonDar)

HIV-infection

Spain
ViiV Healthcare
GlaxoSmithKline

Completed

A Study To Assess GW433908 (Fosamprenavir) Containing Regimens In HIV-1 Infected Subjects

Infection, Human Immunodeficiency Virus

United States, Spain, France, United Kingdom, Chile, Brazil, Italy, Portugal
Kirby Institute

Completed

Raltegravir and Atazanavir Dosing Strategy Study (SPARTA)

HIV Infection

Australia
Bristol-Myers Squibb

Completed

Comparison of Two Anti-HIV Regimens That Include One of Two Forms of Didanosine (ddI)

HIV Infections

United States, Canada
Abbott

Completed

Study in Healthy Adults to Evaluate the Bioavailability of Two Test Tablet Formulations of ABT-450

Healthy

United States
Abbott

Completed

A Study of Ritonavir/Indinavir Combination in HIV-Infected Patients

HIV Infections

United States
Merck Sharp & Dohme LLC

Unknown

The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment

HIV Infections

United States
Federal University of São Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Ramipril, Endothelial Function and Endothelial Progenitor Cells in Patients With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

Brazil
Northwestern University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Juvenile...

Terminated

PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease) (PREVENTKD)

Type 1 Diabetes

United States
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19

COVID-19

United States
Ascletis Pharmaceuticals Co., Ltd.

Completed

Efficacy and Safety of Ravidasvir + Danoprevir/r 12-week Oral Therapy in Treatment-Naive Non Cirrhotic G1 CHC Taiwan

Chronic Hepatitis C
The Ninth Hospital of Nanchang
Ascletis Pharmaceuticals Co., Ltd.

Completed

Evaluation of Ganovo （Danoprevir ） Combined With Ritonavir in the Treatment of SARS-CoV-2 Infection

COVID-19

China
Tongji Hospital

Unknown

A Prospective/Retrospective,Randomized Controlled Clinical Study of Antiviral Therapy in the 2019-nCoV Pneumonia

2019-nCoV

China
Assiut University
Sohag University; South Valley University

Completed

Ombitasvir/ Paritaprevir / Ritonavir Plus Ribavirin in Management HCV and End-stage Kidney Disease

End-stage Renal Disease | HCV Coinfection

Egypt
Children's National Research Institute

Terminated

Optimizing Antiretroviral Therapy in HIV-Infected Children and Adolescents

HIV Infections

United States
AbbVie (prior sponsor, Abbott)

Completed

A Pilot Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ABT-450 With Ritonavir (ABT-450/r) Dosed in Combination With ABT-072 and Ribavirin (RBV)

Hepatitis C | Chronic Hepatitis C Infection | HCV | Hepatitis C Genotype 1

United States
Boehringer Ingelheim

Completed

Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency

Hepatic Insufficiency
Janssen R&D Ireland

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TMC647055 in Combination With Ritonavir (Part 1) and the Co-administration of TMC435, TMC647055 and Ritonavir (Part 2) in Healthy Japanese Participants

Healthy

United Kingdom
Oswaldo Cruz Foundation
Ministry of Health, Brazil

Completed

Pharmacokinetics of the Tablet Formulation of Lopinavir/r as Standard and Increased Dosage During Pregnancy

HIV Infections | Pregnancy

Brazil
Tibotec Pharmaceuticals, Ireland

Completed

A Study to Compare Effectiveness and Safety of Darunavir/Ritonavir (DRV/Rtv) 800mg/100mg Once Daily Versus DRV/Rtv 600mg/100mg Twice Daily in Early Treatment-Experienced HIV-1 Infected Patients (ODIN) (ODIN)

Human Immunodeficiency Virus - Type 1

United States, France, United Kingdom, Germany, Taiwan, Spain, Argentina, Chile, Malaysia, Panama, Romania, South Africa, Thailand, Brazil, Puerto Rico, Austria, Hungary, Australia, Guatemala
Abbott

Completed

Drug Use Investigation of Kaletra

Human Immunodeficiency Virus

Japan
Bamrasnaradura Infectious Diseases Institute

Completed

Ritonavir-boosted Lopinavir Monotherapy

HIV

Thailand
Bristol-Myers Squibb

Completed

Safety and Effectiveness of a New Protease Inhibitor, BMS-232632, in HIV-Positive Patients Who Have Received Previous Treatment

HIV Infections

United States, France, Canada, Italy, Germany
GlaxoSmithKline

Completed

A Study of an Investigational Regimen Combining FDA Approved HIV Drugs in HIV-Infected Subjects

HIV Infection | Infection, Human Immunodeficiency Virus

United States, Puerto Rico
Gathe, Joseph, M.D.

Unknown

Ritonavir and Agenerase Treatment for Patients Who Have Failed Previous Anti-HIV Treatment

HIV Infections

United States
Glaxo Wellcome

Completed

An Open-Label Study to Evaluate the Efficacy and Safety of Amprenavir (141W94) and Abacavir Combination Therapy in Protease Inhibitor Experienced Subjects With HIV-1 Infection Who Are Failing Their Current Antiretroviral Treatment Regimen

HIV Infections

United States
GlaxoSmithKline

Unknown

Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological Failure

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study of Delavirdine Used Together With Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Stereotactic Body Radiation With Nelfinavir for Oligometastases

Oligometastases

United States
Bristol-Myers Squibb

Completed

A Phase IIIB Study Evaluating the Effect on Serum Lipids Following a Switch to Atazanavir in HIV Infected Subjects Evidencing Virologic Suppression on Their First PI-Based Antiretroviral Therapy

HIV Infections

United States
National Institute of Neurological Disorders and...

Completed

HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety and Effectiveness of Ritonavir Plus Lamivudine Plus Zidovudine in HIV-Infected Pregnant Women and Their Babies

HIV Infections | Pregnancy

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study of Ritonavir (an Anti-HIV Drug) in HIV-Positive Infants and Children

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir Soft Gelatin Capsules Plus Zidovudine Plus Lamivudine in the Treatment of HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Fortovase (Saquinavir) Given With Low-Dose Ritonavir, Zidovudine, and Lamivudine to HIV-Positive Pregnant Women During and After Pregnancy and to Their Newborns

HIV Infections | Pregnancy

United States, Puerto Rico
Radboud University Medical Center

Completed

Pharmacokinetic and Safety Study of Raltegravir and Atazanavir in a Once Daily Dose Regimen in HIV-1 Infected Patients (PRADA)

HIV Infections | HIV Infection

Germany, Netherlands
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Effectiveness of Raltegravir Plus Darunavir/Ritonavir in Treatment-Naive HIV-Infected Adults

HIV-1 Infections

United States
ViiV Healthcare
GlaxoSmithKline

Completed

GSK1349572 Drug Interaction Study With Fosamprenavir/Ritonavir

Infections, Human Immunodeficiency Virus and Herpesviridae

United States
Tibotec, Inc
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

Enfuvirtide/Current Protease Inhibitor Switch to PREZISTA (Darunavir)/Ritonavir + TMC125 in HIV Patients With Enfuvirtide Side Effects.

HIV

United States
ViiV Healthcare
Pfizer

Completed

Pharmacokinetics, Safety And Toleration Of Maraviroc Administered To Subjects With Various Degrees Of Renal Impaired And Normal Renal Function

Human Immunodeficiency Virus (HIV) Infection

Germany
French National Agency for Research on AIDS and...
Bristol-Myers Squibb; Gilead Sciences

Terminated

Efficacy and Safety of Tenofovir DF/Atazanavir Enhanced With Low Dose of Ritonavir in HIV-Infected Patients

HIV Infections

France
Medical University Innsbruck
Ludwig-Maximilians - University of Munich; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Completed

Stopping ACE-inhibitors in COVID-19 (ACEI-COVID)

COVID-19 | SARS-CoV-2

Germany, Austria
Techpool Bio-Pharma Co., Ltd.
Center for ADR Monitoring of Guangdong

Unknown

Post-market Safety Reassessment of Ulinastatin for Injection

Adverse Reaction to Drug

China
Techpool Bio-Pharma Co., Ltd.
The First Affiliated Hospital of Guangzhou Medical University

Unknown

The Safety and Dose Response Relationship of Ulinastatin for Acute Respiratory Distress Syndrome(ARDS)

Acute Respiratory Distress Syndrome

China
Boehringer Ingelheim

Completed

Investigation of Ritonavir Effects on Afatinib Exposure in Healthy Subjects

Healthy

Germany
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

To Evaluate SSD8432/Ritonavir in Adults With COVID-19

COVID-19

3

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