Search clinical trials for: Proton Pump Inhibitor

Total 68328 results

Janssen-Cilag Pty Ltd

Completed

A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg or Esomeprazole 40mg

Gastro-oesophageal Reflux

Australia
Eisai Co., Ltd.

Completed

A Study of E3810 for Japanese Subjects With Functional Dyspepsia (SAMURAI Study: Suppression of Acid Milieu With Rabeprazole Improving Functional Dyspepsia ) (Study E3810-J081-204)

Functional Dyspepsia

Japan
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Eisai Inc.
Eisai Limited

Completed

A Study of E3810 With Pre- and Post-Treatment pH Monitoring in Patients With Non-Erosive Gastroesophageal Reflux Disease

Non-erosive Gastroesophageal Reflux Disease

Japan
AstraZeneca

Completed

An Open-label, Exploratory Trial to Assess Gastric Acid Control in Critically Ill Subjects Receiving Nexium

Gastric Ulcer

United States
Johnson & Johnson Pharmaceutical Research & Development...
Eisai Inc.

Completed

A Pharmacokinetic and Safety Study of Single and Multiple Doses of Rabreprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Years Old, Inclusive

GERD
Janssen Cilag Pharmaceutica S.A.C.I., Greece

Completed

Study of the Safety and Effectiveness of Rabeprazole in Treatment of Helicobacter Pylori Infection in Adults.

Bacterial Infections | Helicobacter Infections
Janssen Cilag Pharmaceutica S.A.C.I., Greece

Completed

A Study of the Safety of Rabeprazole Administered to Adults With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux | Heartburn
AstraZeneca

Completed

The Effect of Lifestyle-Adjustments Prior to Medical Treatment on the Effect of Medical Treatment in Reflux Patients

Quality of Life | GERD

Netherlands
Università degli Studi di Ferrara

Unknown

Effect of Proton Pump Inhibitor on Residual Platelet Reactivity After Clopidogrel in Homogenous Genetic Strata (GENIOUS)

Coronary Stenting

Italy
Teva Pharmaceuticals USA

Completed

Pantoprazole Sodium 40 mg DR Tablets Under Non-Fasting Conditions

Healthy

United States
Shanghai Jiao Tong University School of Medicine

Completed

High Dose Amoxicillin Versus Tetracycline as Second-line Treatment of Resistant Helicobacter Pylori Infection

Helicobacter Pylori Treatment Failure

China
Norfolk and Norwich University Hospitals NHS Foundation...
Norwich Clinical Trials Unit

Recruiting

Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole (TIPAL)

Idiopathic Pulmonary Fibrosis

United Kingdom
Universitaire Ziekenhuizen KU Leuven

Recruiting

Neuro-immune Interactions and PPI

Functional Dyspepsia

Belgium
University of Colorado, Denver
Children's Hospital Colorado

Recruiting

Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE)

Eosinophilic Esophagitis

United States
Northwestern University
Washington University School of Medicine; Vanderbilt University

Completed

Effectiveness of Physiologic Testing in PPI Non-Responders

Gastro Esophageal Reflux

United States
Jiangsu HengRui Medicine Co., Ltd.
The Third Xiangya Hospital of Central South University

Completed

Effect of Omeprazole on PK of Fluzoparib in Healthy Male Subjects

Advanced Solid Tumor

China
Columbia University

Completed

Effect of Proton Pump Inhibitors on CF Pulmonary Exacerbations

Cystic Fibrosis

United States
McMaster University
Canadian Institutes of Health Research (CIHR)

Completed

Pediatric Intensive Care Ulcer Prophylaxis Pilot Trial (PIC-UP)

Gastrointestinal Hemorrhage

Canada
First Affiliated Hospital of Zhejiang University
Beijing Xuze Medical Technology Co., LTD.

Completed

Pharmacokinetic Study of Lansoprazole Capsules in Healthy Chinese Volunteer

Safety Issues | Effect of Drugs

China
Emilio Vargas Castrillón
Fundación Mutua Madrileña

Completed

Study to Compare the Bioavailability of Omeprazole 20 mg Before and After Undergoing Surgery for Morbid Obesity (OBS-2011/001)

Bariatric Surgery Candidate

Spain
Ascension Genesys Hospital

Terminated

Anti-reflux Control to Decrease Post Tonsillectomy Pain

Laryngopharyngeal Reflux | Throat Pain

United States
Damascus Hospital

Completed

Efficacy of Low Dose of Proton Pump Inhibitor in Treatment Bleeding Ulcers

Peptic Ulcer Hemorrhage | Marginal Ulcer | Gastroduodenal Ulcer

Syrian Arab Republic
Elpen Pharmaceutical Co. Inc.

Completed

10-day Versus 14-day Concomitant PAMC as First-line Treatment Strategy for the Eradication of H. Pylori Infection

Helicobacter Pylori Infection

Greece
Genentech, Inc.

Completed

A Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0941 and the Effect of Food and Proton Pump Inhibition on GDC-0941 Tablet Pharmacokinetics in Healthy Volunteers

Healthy Volunteers

United States
National Cheng-Kung University Hospital

Unknown

Treatment Effect Between Dexlansoprazole and Double-dose Lansoprazole in Obesity Patients With Reflux Esophagitis

Gastroesophageal Reflux Disease
University of Utah
AstraZeneca

Terminated

Effect of Acid Reflux on Respiratory Physiology During Exercise in Athletes With GER-Response to Acid Suppression

Gastroesophageal Reflux | Exercise Triggered Asthma

United States
Janssen Korea, Ltd., Korea

Completed

Practice and Patient Compliance on the PPI (Proton Pump Inhibitors) Treatment of Gastroesophageal Reflux in South Korea

Gastroesophageal Reflux
Soroka University Medical Center

Unknown

Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC

CDA Type I
AstraZeneca

Completed

Study of 24-hour Intragastric pH Profiles of Esomeprazole 40 mg and Lansoprazole 30 mg in Healthy Volunteer Subjects

Healthy

United States
West Side ENT

Withdrawn

Tongue Exercises and Reflux Therapy for Upper Airway Resistance Syndrome

Obstructive Sleep Apnea | Gastroesophageal Reflux | Upper Airway Resistance Syndrome
City of Hope Medical Center

Completed

Plasm Gastrin Concentrations in Response to Nexium Administration in Healthy Volunteers

Healthy

United States
Assistance Publique - Hôpitaux de Paris

Completed

Optimal Dosing of Omeprazole in Neonates (OMEPRAZOLE-1)

Gastroesophageal Reflux Disease (GERD)

France
Pfizer

Terminated

Efficacy And Safety Of PF-00885706 For The Relief Of Symptoms In Subjects With Gastro-esophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

Brazil, Germany, Korea, Republic of, Belgium, Spain, Slovakia, France
National University Hospital, Singapore

Completed

Study Using Esomeprazole as a Diagnostic Test for GERD in Patients With NCCP (ECP)

Gastroesophageal Reflux Disease

Singapore
Eisai Inc.

Completed

Treatment of Gastroesophageal Reflux Disease in 12-16 Year Old Patients With Rabeprazole

Gastroesophageal Reflux Disease

United States
AstraZeneca

Completed

Pharmacokinetic Study of Esomeprazole Magnesium in Patients 1 to 11 Years-Old With Endoscopically-Proven Gastroesophageal Reflux Disease (GERD)

Reflux | Endoscopically-Proven GERD
Henan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Apatinib Treatment for Advanced Esophagus Cancer

Advanced Esophagus Cancer

China
Wuhan Union Hospital, China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Apatinib Combined With Chemotherapy Versus Chemotherapy in Second-line Gastric Cancer Receiving Prior Anti-PD-1 Therapy

Gastric Cancer | Randomized Controlled Study

China
The First Affiliated Hospital of Zhengzhou University
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study of Second-line Treatment With Apatinib for Advanced Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma

China
Fudan University

Unknown

Apatinib for Advanced Biliary Carcinoma

Biliary Tract Neoplasms

China
Cairo University

Recruiting

Baduanjin Program Effect on Geriatric Functional Dyspepsia

Functional Dyspepsia

Egypt
Aya Mohamed Sadek Elsaid

Not yet recruiting

The Possible Protective Role of Omeprazole Against Oxaliplatin Induced Neuropathy in Cancer Patients

Chemotherapy Induced Peripheral Neuropathy
Dr. Morten Hylander Møller
Rigshospitalet, Denmark; Copenhagen Trial Unit, Center for Clinical Intervention...

Completed

Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU)

Gastrointestinal Bleeding | Stress Ulcers

Denmark, Netherlands, Switzerland, Norway, Finland, United Kingdom
Boston Children's Hospital

Terminated

The Effects of Reducing Stomach Acid on Post-tonsillectomy Pain

Post-tonsillectomy Pain | Post-tonsillectomy Activity | Post-tonsillectomy Hydration

United States
Genuine Research Center, Egypt
Future Pharmaceuticals Industries, Egypt

Completed

Bioequivalence Study of Esomeprazole From Stomopral 40 mg Capsules Contain Enteric Coated Pellets (Future Pharmaceuticals Industries, Egypt) and Nexium 40 mg Delayed Release Capsules (AstraZeneca Sweden, Product of France)

Healthy

Egypt
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-214-02 and Rabeprazole

Gastroesophageal Reflux Disease

Korea, Republic of
First Affiliated Hospital of Zhejiang University
Beijing Xuze Medical Technology Co., LTD.

Completed

PK-PD Comparative Study of Lansoprazole Capsules and Lansoprazole Enteric-coated Capsules in Healthy Chinese Volunteers

Safety Issues | Effect of Drugs

China
Peking University First Hospital

Unknown

Effect of Food on Pharmacokinetics of Salvianolic Acid A in Healthy Subjects

Healthy

China
Khon Kaen University
Thai Rheumatism Association

Completed

Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis

Gastroesophageal Reflux | Systemic Sclerosis | Proton Pubm Inhibitor

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