Search clinical trials for: Proton Pump Inhibitors

Total 68141 results

University of Kansas Medical Center
TAP Pharmaceutical Products Inc.

Terminated

Dietary Control Alone Versus Dietary Control Plus Use of Proton Pump Inhibitors to Treat Pediatric Hoarseness

Dysphonia

United States
The University of Hong Kong

Completed

PPI for Prevention of Post-sphincterotomy Bleeding

Bleeding | ERCP

China
Soonchunhyang University Hospital

Unknown

Dexlansoprazole MR in Nonerosive Reflux Disease

Nonerosive Reflux Disease

Korea, Republic of
Eisai Co., Ltd.

Completed

Double-blind Comparative Study of E3810 Tablets (10 or 20 mg b.i.d.) to Evaluate Efficacy and Safety in Patients With Refractory Reflux Esophagitis

Refractory Reflux Esophagitis

Japan
Forest Laboratories

Completed

The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.

Dyspepsia

United States
Mayo Clinic
AstraZeneca

Completed

Which Supraesophageal Reflux Symptoms Reliably Respond to Proton-Pump-Inhibitor (PPI) Therapy

Gastroesophageal Reflux

United States
Eisai Co., Ltd.

Completed

A Comparative Study on the Efficacy and Safety of E3810 in Patients With Non-erosive Gastroesophageal Reflux Disease

Non-erosive Gastroesophageal Reflux Disease

Japan
Janssen-Cilag, S.A.

Terminated

Influence of Hygiene-dietetic Habits and Treatment Adherence on the Effectiveness of the Gastroesophageal Reflux Illness Treatment With Rabeprazol

Gastroesophageal Reflux
AstraZeneca

Completed

Chronic Posterior Laryngitis With Suspected Laryngopharyngeal Reflux

Chronic Posterior Laryngitis (CPL)
Takeda

Completed

Intravenous vs Oral Lansoprazole on Gastric Acid Secretion in Subjects With Erosive Esophagitis

Esophagitis | Reflux
Lotung Poh-Ai Hospital

Completed

Intravenous Proton Pump Inhibitor for Peptic Ulcer Bleeding (PPI)

Peptic Ulcer Hemorrhage

Taiwan
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Unknown

Effect and Safety of Apatinib on Radiation-Induced Brain Injury

Radiation Injuries

China
Cairo University

Recruiting

Baduanjin Program Effect on Geriatric Functional Dyspepsia

Functional Dyspepsia

Egypt
Aya Mohamed Sadek Elsaid

Not yet recruiting

The Possible Protective Role of Omeprazole Against Oxaliplatin Induced Neuropathy in Cancer Patients

Chemotherapy Induced Peripheral Neuropathy
Dr. Morten Hylander Møller
Rigshospitalet, Denmark; Copenhagen Trial Unit, Center for Clinical Intervention...

Completed

Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU)

Gastrointestinal Bleeding | Stress Ulcers

Denmark, Netherlands, Switzerland, Norway, Finland, United Kingdom
Boston Children's Hospital

Terminated

The Effects of Reducing Stomach Acid on Post-tonsillectomy Pain

Post-tonsillectomy Pain | Post-tonsillectomy Activity | Post-tonsillectomy Hydration

United States
Genuine Research Center, Egypt
Future Pharmaceuticals Industries, Egypt

Completed

Bioequivalence Study of Esomeprazole From Stomopral 40 mg Capsules Contain Enteric Coated Pellets (Future Pharmaceuticals Industries, Egypt) and Nexium 40 mg Delayed Release Capsules (AstraZeneca Sweden, Product of France)

Healthy

Egypt
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-214-02 and Rabeprazole

Gastroesophageal Reflux Disease

Korea, Republic of
First Affiliated Hospital of Zhejiang University
Beijing Xuze Medical Technology Co., LTD.

Completed

PK-PD Comparative Study of Lansoprazole Capsules and Lansoprazole Enteric-coated Capsules in Healthy Chinese Volunteers

Safety Issues | Effect of Drugs

China
Peking University First Hospital

Unknown

Effect of Food on Pharmacokinetics of Salvianolic Acid A in Healthy Subjects

Healthy

China
Khon Kaen University
Thai Rheumatism Association

Completed

Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis

Gastroesophageal Reflux | Systemic Sclerosis | Proton Pubm Inhibitor
Xijing Hospital of Digestive Diseases

Completed

The Efficacy of Esomeprazole Premedication on Intraoperative Bleeding During Gastric ESD

Stomach Neoplasms

China
Celgene

Completed

A Study to Evaluate the Effect of Food, Formulation Strength, and a Proton Pump Inhibitor on GED 0301 Pharmacokinetics in Healthy Adult Subjects

Healthy Volunteers

United Kingdom
Puma Biotechnology, Inc.

Completed

Open-label PK Study to Evaluate Lansoprazole and Neratinib in Healthy Subjects

Healthy

United States
Genuine Research Center, Egypt
Hikma Pharma,Egypt

Completed

A Bioequivalence Study of Dexlansoprazole From Doxirazole 60 mg Capsules (Hikma Pharma,Egypt)and Dexilant 60 mg Delayed Release (DR) Capsules (Takeda Pharmaceuticals America Inc., USA)

Healthy

Egypt
Cancer Advances Inc.

Completed

Effect of G17DT in Patients With Stage II/III Colorectal Cancer (CC5)

Colorectal Cancer
Takeda

Completed

Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents

Gastroesophageal Reflux Disease | Erosive Esophagitis

United States, Poland, Belgium, Portugal, Italy, Hungary, Mexico, Brazil
Hamilton Health Sciences Corporation
McMaster University

Completed

Study of Anti-reflux Medication as a Potential Treatment for Glue Ear in Children

Otitis Media With Effusion

Canada
Boehringer Ingelheim

Completed

Bioavailability of Oral BIRB 796 BS Tablets With and Without Administration of Oral Pantoprazole in Healthy Male Volunteers

Healthy
National Taiwan University Hospital
Takeda

Terminated

Lansoprazole for Subgroups of Functional Dyspepsia

Functional Dyspepsia

Taiwan
Seoul National University Hospital

Completed

Lansoprazole in Preterm Infants With Reflux

Preterm Infants | Gastrointestinal Reflux

Korea, Republic of
Norgine

Completed

Phase III Study Comparing Zegerid® With Losec® for the Relief of Heartburn Associated With Gastroesophageal Reflux Disease

Gastroesophageal Reflux

Poland
AstraZeneca
Parexel

Completed

To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole

Gastroesophageal Reflux Disease | GERD | Reflux Esophagitis
Il-Yang Pharm. Co., Ltd.

Completed

Efficacy Study of Ilaprazole to Treat Erosive Esophgitis

GERD | Erosive Esophagitis

Korea, Republic of
HSK Wiesbaden

Terminated

APE-Study: Ablation of Barrett's Mucosa vs. Surveillance Without Ablation in Patients Cured From Barrett's Cancer Combined With Randomization of Esomeprazole vs. Placebo for Symptomatic Reflux Control After Successful Barrett's Ablation (APE)

Barrett's Esophagus

Germany
Eisai Inc.

Completed

A Study to Investigate Use Patterns and Safety in Simulated Actual Over-the-counter (OTC) Use of Rabeprazole Sodium for the Treatment of Heartburn Symptoms

Frequent Heartburn

United States
AstraZeneca

Completed

Ulcer Prevention II

NSAID Associated Gastric Ulcers
AstraZeneca

Completed

Esomeprazole for Treatment of GERD in Pediatric Patients

Gastroesophageal Reflux Disease (GERD) | Erosive Esophagitis | Non-erosive Esophagitis

United States, France, Italy, Belgium
AstraZeneca

Completed

Acid-Associated Heartburn Symptoms and Dose of Esomeprazole

Heartburn

United States, Puerto Rico
Novartis

Completed

Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn

Heartburn

United States
AstraZeneca

Completed

An Open Label pH Comparison of Esomeprazole and Lansoprazole in Barrett's Esophagus Patients

Barrett's Esophagus

United States
AstraZeneca

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)
AstraZeneca

Completed

Validation of RDQ Questionnaire

Gastroesophageal Reflux

Sweden, United Kingdom, Germany, Canada, Denmark, Norway
Shanghai Jiao Tong University School of Medicine

Completed

High Dose Amoxicillin Versus Tetracycline as Second-line Treatment of Resistant Helicobacter Pylori Infection

Helicobacter Pylori Treatment Failure

China
AstraZeneca

Completed

A Randomized, Open-Label, Comparative 3-Way Treatment Crossover Study of 24-Hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40mg, Lansoprazole 30mg, and Pantoprazole 40mg at Steady State in NSAID-Using Patients

Nausea | Heartburn | Acid Regurgitation | Upper Abdominal Pain
The University of Hong Kong

Terminated

Effect of Second-look Endoscopy on Peptic Ulcer Rebleeding in Patients With Early Resumption of Antiplatelet Agents

Gastric Ulcer Induced by Anti-platelet Agent | Duodenal Ulcer Induced by Anti-platelet Agent | OGD

China, Hong Kong
Shandong University
Zibo Central Hospital; Peking University Care Luzhong Hospital; Yuncheng Traditional... and other collaborators

Not yet recruiting

Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Therapy of Different Tetracycline Doses and Frequencies.

Helicobacter Pylori Infection
Shanghai Jiao Tong University School of Medicine

Completed

Efficiency Study of Clarithromycin and Bismuth-containing Quadruple Therapy to Treat H.Pylori

Functional Dyspepsia | Peptic Ulcer | Helicobacter Pylori

China
Celgene

Not yet recruiting

Study to Evaluate Safety, Drug Levels, Food and Relative Bioavailability of BMS-986365 in Healthy Adult Male Participants

Healthy Participants

United States
Rush University Medical Center

Recruiting

Esomeprazole and Radiation Induced Esophagitis (EERENs)

Locally Advanced Lung Carcinoma | Radiation Esophagitis

United States

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