Search clinical trials for: Pulsatile Intravenous Insulin Therapy (Humulin, Humulog, Novolog )

Total 137 results

Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Clinical Effects of Pulsatile Insulin Delivery on Cognitive Function- Phase 1

Diabetes Mellitus

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effects of Pulsed Intravenous (IV) Insulin on Brittle and Uncontrolled Diabetes

Diabetes Mellitus

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effects of Pulsatile Intravenous (IV) Insulin on Wound Healing in Diabetics (wounds)

Diabetes | Wound Healing

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Withdrawn

Effects of Pulsatile Intravenous Insulin Delivery on Diabetic Neuropathy in pATIENTS (Pts) With Type 1 and Type 2 Diabetes

Diabetic Neuropathy

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Withdrawn

Effects of Pulsatile Intravenous Insulin Delivery on Hypoglycemic Unawareness

Hypoglycemia

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effects of Pulsatile Intravenous Insulin Therapy on Metabolic Integrity in Patients With Diabetes Mellitus

Diabetes Mellitus, With Complications

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Terminated

Effects of Pulsatile Insulin Delivery on Diabetic Neuropathy in Patients With Types 1 and 2 Diabetes Mellitus

Diabetes Mellitus, With Complications

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effect Pulsatile IV Insulin Therapy on the Quality of Life in Patients With Types 1 and 2 Diabetes

Diabetes Mellitus

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effect of Pulsatile IV Insulin on Circulating Risk Markers of Vascular and Metabolic Complications in Pts With Diabetes

Diabetes Mellitus

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Terminated

Effects of Pulsatile IV Insulin Delivery on Diabetic Retinopathy in Patients With Types 1 and 2 Diabetes Mellitus

Diabetes Mellitus, With Complications

United States
Global Infusion and Aspiration Systems, LLC

Unknown

Effects of Intensive Bolus Intravenous Insulin Delivery on Metabolic Integrity in Type 1 and Type 2 Diabetes

Diabetes Mellitus | Metabolic Integrity

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Withdrawn

Effects of Pulsatile Intravenous Insulin Therapy on Cardiac Disease in Patients With Diabetes

Diabetes Mellitus, With Complications

United States
University of North Carolina, Chapel Hill
WakeMed Health and Hospitals

Completed

Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes (MIPOD)

Pregnancy | Non Insulin Dependent Diabetes

United States
Vancouver General Hospital

Terminated

Insulin Therapy for Post-transplant Glucocorticoid Induced Hyperglycemia (PTHG)

Post-Transplant Glucocorticoid Induced Diabetes

Canada
Sansum Diabetes Research Institute
Sanofi

Completed

Comparator Trial Using Insulin Glulisine vs. Insulin Lispro for Treatment of Gestational Diabetes

Diabetes During Pregnancy

United States
Halozyme Therapeutics

Completed

Pharmacokinetic (PK), Pharmacodynamic (PD), and Safety Study of Subcutaneously Administered Humalog® With and Without Recombinant Human Hyaluronidase (rHuPH20)and Humulin-R® With and Without rHuPH20

Diabetes Mellitus

United States
Halozyme Therapeutics

Completed

Liquid Meal Study With Insulin Lispro With/Without Recombinant Human Hyaluronidase PH20 (rHuPH20) and Regular Human Insulin With rHuPH20 to Compare Pharmacokinetics, Postprandial Glycemic Response, and Optimal Insulin Dose in Participants With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

United States
Northwestern University

Terminated

Use of NPH Versus Basal Bolus Insulin for Steroid Induced Hyperglycemia

Insulin Resistance, Diabetes | Hyperglycemia Steroid-induced

United States
Becton, Dickinson and Company

Completed

Feasibility Study of the Effect of Intra-Dermal Insulin Injection on Blood Glucose Levels After Eating

Diabetes Mellitus, Type 1

Germany
University of Roma La Sapienza

Completed

Humalog or Humulin for Intensive Insulin Therapy in Intensive Care Unit

Hyperglycemia

Italy
Halozyme Therapeutics

Completed

Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Emory University

Completed

Sitagliptin for Hyperglycemia in Patients With T2DM Undergoing Cardiac Surgery (SITA-CABGDM)

Hyperglycemia

United States
Eli Lilly and Company

Completed

Safety and Efficacy Study of Insulin Lispro Versus Insulin Aspart in Participants With Type 2 Diabetes on Insulin Pump Therapy

Type 2 Diabetes Mellitus

United States
Halozyme Therapeutics

Completed

Dose-Ranging, Pharmacokinetic (PK), Glucodynamic (GD), Safety and Tolerability Study of Subcutaneously (SC) Administered Humulin R and Humalog With or Without rHuPH20

Healthy Volunteers

United States
Emory University

Completed

Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery (SITACABG NonDM)

Coronary Artery Disease

United States
Eli Lilly and Company

Terminated

Hospital Management of Hyperglycemia Study of Insulin Glargine Plus Insulin Lispro Versus Human Regular Insulin (HMH)

Hyperglycemia

United States
Geropharm

Completed

Efficacy and Safety of Insulin Rinsulin® NPH Compared to Humulin® NPH in Type 2 Diabetes Mellitus Patients

Diabetes Mellitus, Type 2

Russian Federation
University of Massachusetts, Worcester

Completed

Effect of Single Dose Intranasal Insulin On Cognitive Function

Schizophrenia | Schizoaffective Disorder

United States
Halozyme Therapeutics

Completed

Pharmacokinetic and Glucodynamic Crossover Study of Subcutaneously (SC) Administered Insulin Lispro + Recombinant Human Hyaluronidase (rHuPH20) and Regular Human Insulin + rHuPH20 Compared to Insulin Lispro Alone

Diabetes Mellitus

United States
Transdermal Delivery Solutions Corp
Langford Research Institute, Inc.

Not yet recruiting

Dose Response Study of Transdermal Human Insulin in Patients (LEVPS)

Glucose, High Blood

United States
Arkansas Children's Hospital Research Institute

Completed

Preservation of Pancreatic Beta Cell Function Through Insulin Pump Therapy (ktpump)

Diabetes Mellitus

United States
Joslin Diabetes Center
Novo Nordisk A/S

Terminated

Glycemic Stability of Insulin Aspart Versus Insulin Lispro in Insulin Pump Therapy

Type 1 Diabetes Mellitus

United States
Providence Health & Services

Withdrawn

Comparison Study of Insulin Glargine and NPH Insulin

Diabetes

United States
Geropharm

Completed

Comparative Study of Rinsulin R (GEROPHARM) and Humulin Regular (Eli Lilly) Euglycemic Hyperinsulinemic Clamp Method

Bioequivalence | Therapeutic Equivalency

Russian Federation
Mayo Clinic
Arizona State University

Terminated

Molecular Regulation of Muscle Glucose Metabolism

Obesity | Type 2 Diabetes Mellitus

United States
Geropharm

Completed

Comparative Study of Rinsulin® NPH, Suspension for Subcutaneous Administration, 100 IU/ml (GEROPHARM LLC, Russia) and Humulin® NPH, Suspension for Subcutaneous Administration, 100 IU/ml (Lilly France, France) Using the Euglycemic Hyperinsulinemic Clamp Method

Pharmacokinetics | Bioequivalence

Russian Federation
Halozyme Therapeutics

Completed

Safety Study of Subcutaneously-Injected Prandial INSULIN-PH20 NP Compared to Insulin Lispro Injection in Participants With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

United States
University of Florida
Sanofi

Completed

Effect of Apidra Compared to Humalog in Decreasing Post-Prandial Hyperglycemia

Type 1 Diabetes

United States
Tulane University Health Sciences Center

Completed

Comparison of Insulins Aspart and Lispro in Insulin Pumps

Type 1 Diabetes Mellitus

United States
Biodel

Completed

BIOD-531 vs. Humalog Mix 75/25 vs. Humulin R U-500 Post-Meal Glucose Control in Patients With Severe Insulin Resistance

Diabetes Mellitus

United States
Biodel

Completed

Comparison of Postprandial Glucose Control Associated With BIOD-531 vs. Humalog Mix 75/25 vs. Humulin R U-500

Type 2 Diabetes Mellitus

United States
Sanofi

Terminated

Evaluation of Virtual Versus Traditional Study Conducted in a Group Pilot Study in Adult Patients With Type 1 Diabetes Mellitus (eStudy)

Type 1 Diabetes Mellitus

United States, Canada
Second Affiliated Hospital, School of Medicine,...

Recruiting

Safety and Efficacy of Insulin Degludec/Insulin Aspart in Patients With T1DM

Time in Range | HbA1c | Type 1 Diabetes Mellitus With Diabetic Gastroparesis

China
Adocia

Completed

A Trial to Investigate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BioChaperone® Pramlintide Insulin in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Germany
Massachusetts General Hospital
Boston University

Terminated

Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas

Type 1 Diabetes Mellitus

United States
Eli Lilly and Company

Terminated

A Study of U-500 Insulin (LY041001) in Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Completed

SPECS: Safe Pediatric Euglycemia in Cardiac Surgery (SPECS)

Hyperglycemia | Heart Defects, Congenital

United States
Geropharm

Completed

Comparative Study of the Pharmacokinetics of Rinsulin® Mix 30/70, Suspension for Subcutaneous Administration, 100 IU / ml (OJSC GEROPHARM-Bio, Russia) and Humulin® M3, Suspension for Subcutaneous Administration, 100 IU / ml (Lilly France, France) Using the Euglycemic Hyperinsulinemic Clamp Method

Bioequivalence

Russian Federation
Halozyme Therapeutics

Completed

Randomized, Double Blind, 2 Way Crossover Study of CSII With, Versus Without, Pretreatment With Human Hyaluronidase

Type 1 Diabetes Mellitus

United States
Sanofi

Completed

Compare Blood Sugar Level Between Lantus in the Morning and Other Insulins in Type 1 Diabetes Adolescents

Diabetes Mellitus

United States

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