Search clinical trials for: Pyruvate (13C)

Total 1980 results

Motus Therapeutics, Inc.

Completed

Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation

Constipation

United States
Motus Therapeutics, Inc.

Completed

Phase 2 Study to Evaluate Safety & Efficacy of RM-131 Administered to Patients With Diabetic Gastroparesis

Diabetes Mellitus | Gastroparesis | Diabetes Mellitus Complications

United States
Kissei Pharmaceutical Co., Ltd.

Completed

Study of Absorption, Metabolism and Excretion Following a Single Oral Dose of [14C]KWA-0711 to Healthy Male Subjects

Healthy Male Subject

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of VX-135 and Daclatasvir in Subjects With Genotype 1 Chronic Hepatitis C Chronic Hepatitis C

Hepatitis C | Chronic Hepatitis C | HCV | CHC

New Zealand
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure

Congestive Heart Failure

Bulgaria
FDA Office of Orphan Products Development
Children's Hospital and Health Center

Completed

Liothyronine in Children With Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedure

Heart Defects, Congenital | Tricuspid Atresia
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Effect of ASP1707 on the Bodies of Healthy Male Subjects After a Single Dose of Radioactive ASP1707

Pharmacokinetics of ASP1707

United Kingdom
Massachusetts General Hospital

Terminated

11C Acetate Imaging Post Prostatectomy

Prostate Cancer

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study GSI-136 in Healthy Young and Healthy Elderly Subjects

Healthy | Alzheimer Disease

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Safety of GSI 136 in Young and Elderly Japanese Males

Healthy | Alzheimer Disease

Japan
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Healthy Participants

Netherlands
Boehringer Ingelheim

Completed

Pharmacokinetics of Talsaclidine After Administration to Healthy Subjects

Healthy
Centocor Research & Development, Inc.

Completed

A Study of the Safety and Pharmacokinetics of CNTO 136 in Patients With Cutaneous Lupus Erythematosus and Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic | Lupus Erythematosus, Cutaneous
James M Noble, MD, MS, CPH, FAAN
National Institute on Aging (NIA)

Enrolling by invitation

Imaging Inflammation in Alzheimer's Disease

Alzheimer's Disease

United States
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Mass Balance of [14C] SY-5007 in Healthy Adult Male Subjects in China

Healthy Subjects

China
Guangzhou Lupeng Pharmaceutical Company LTD.

Completed

The Mass Balance Study of LP-168 in Healthy Subjects

Clinical Pharmacology

China
Amgen

Active, not recruiting

Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus

Obesity | Overweight | Type 2 Diabetes Mellitus

United States, Czechia, Taiwan, Canada, Japan, Korea, Republic of, Germany, Hungary, Australia, Hong Kong, Spain, Poland
InventisBio Co., Ltd

Completed

Study in Healthy Adult Female Subjects

Mass Balance Recovery

United States
University of Aarhus

Completed

Validation of 3-[11C]-OHB

Heart Failure | Healthy | Diabetes Mellitus, Type 2

Denmark
Sagimet Biosciences Inc.

Active, not recruiting

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]TVB-2640 Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
TenNor Therapeutics Limited

Completed

Absorption, Metabolism, and Excretion Study of [14C]-TNP-2092

Healthy

United States
Pyramid Biosciences

Completed

A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200

Absorption, Metabolism and Excretion in Healthy Volunteers

United States
H. Lundbeck A/S

Completed

A Brain Imaging PET Study of [11C]-Lu AF88370 in Healthy Adult Male Participants

Healthy Participants

United Kingdom
H. Lundbeck A/S

Completed

A Brain Imaging PET Study of [11C]-Lu AF90103 in Healthy Adult Male Participants

Healthy Young Men

Sweden
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study of Human Substance Balance and Biotransformation of [14C]SHR0302

Rheumatoid Arthritis (RA)

China
Senju Pharmaceutical Co., Ltd.
Quotient Sciences

Completed

Single Dose ADME Study of [14C]SJP-0008 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Spectrum Pharmaceuticals, Inc

Terminated

A Mass Balance and Pharmacokinetics Study of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment With Poziotinib

Solid Tumor

United States
Resolve Therapeutics
Newcastle-upon-Tyne Hospitals NHS Trust; University Hospital Birmingham

Completed

A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome (RSLV-132)

Sjogren's Syndrome

United Kingdom
Eisai Limited

Completed

A Study to Determine the Metabolism and Elimination of [14C]E7090 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Perosphere Pharmaceuticals Inc, a wholly owned...
World Wide Clinical Trials Early Phase Services, LLC

Completed

An Open-label, Single-dose, Non-randomized Study of IV 14C-labeled PER977 in Healthy Male Subjects

Healthy

United States
Eli Lilly and Company

Completed

A Study of LY3214996 in Healthy Participants

Healthy

United States
Entasis Therapeutics

Completed

Study to Determine the Excretion and Metabolism of 14C-ETX2514 Administered Intravenously in Healthy Male Subjects

Acinetobacter Baumannii-calcoaceticus Complex Infections

United States
Eli Lilly and Company

Completed

Study of LY3154207 in Healthy Participants

Healthy

United States
Balance Therapeutics

Completed

A Study to Investigate the Mass Balance of BTD-001 (HV103)

Molecular Mechanisms of Pharmacological Action

United Kingdom
Pfizer

Completed

Test Re-Test Reliability of [11C]PF-06809247 as a Novel PET Tacer

Neuroinflammation

United States
Bioprojet

Completed

Study to Assess the Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]-Pitolisant in Healthy Male Volunteers

Healthy Volunteers
Pfizer

Completed

A Study To Investigate The Absorption, Distribution, Metabolism, And Excretion Of [14c]PF-06463922 In Healthy Male Volunteers

Healthy

United States
Pfizer

Completed

A Study To Understand How Radiolabelled PF-04449913 Is Taken Up By The Body, Broken Down And Then Removed From The Body

Healthy

United States
Ono Pharmaceutical Co. Ltd

Completed

A Human Mass Balance Study to Determine the Total Recovery of Radioactivity in Urine and Faeces Following a Single Oral Dose of 14C Radiolabelled ONO-4053

Healthy Adult Male Subjects

United Kingdom
Takeda

Completed

Safety and Efficacy Study of Once and Twice Daily Doses of MCC-135 in Subjects With Congestive Heart Failure.

Congestive Heart Failure

United States
Biomed Research & Technologies, Inc.

Completed

A Study of BRT-FC-83C for the Treatment of Atopic Dermatitis

Atopic Dermatitis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study of the Safety, Tolerability, and Pharmacokinetics of GAP-134 Administered Intravenously

Healthy Subjects

United States
Eisai Limited

Completed

A Study to Determine the Absolute Bioavailability and the Absorption, Metabolism, and Elimination Properties of Carbon-14 (14C)E7386 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Johns Hopkins University
Radiological Society of North America

Recruiting

Long COVID-19 [11C]CPPC Study

COVID Long-Haul

United States
National Institute of Mental Health (NIMH)

Recruiting

PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

Depression

United States
Robert Fox
Case Western Reserve University

Not yet recruiting

Study Evaluating the Safety of Myeliviz Myelin-Targeting PET Agent

Healthy

United States
Amgen

Completed

Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity

Obesity

United States
Eli Lilly and Company

Active, not recruiting

A Study of Carbon-14-Labelled [14C] LY3473329 in Healthy Male Participants

Healthy

United Kingdom
Eli Lilly and Company

Completed

A Phase I Study of LY3502970 in Healthy Participants

Healthy

United States
Jacobio Pharmaceuticals Co., Ltd.

Completed

Mass Balance Study of [14C]JAB-21822

Mass Balance Study in Healthy Subjects

China

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