Search clinical trials for: RLY-4008

Total 1917 results

Relay Therapeutics, Inc.

Active, not recruiting

REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors

Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Amplification | FGFR2 Gene Fusion/Rearrangement | FGFR2 Gene Translocation | FGFR2 Gene Activation | Other Solid Tumors, Adult

United States, France, Italy, United Kingdom, Korea, Republic of, Spain, Taiwan, Sweden, Germany, Netherlands, Singapore, Australia, Hong Kong
University of Cincinnati

Completed

End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA)

End Stage Liver Disease

United States
Hungarian Institute of Cardiology

Unknown

Body Composition Measurements in Chronic Heart Failure

Body Composition | Sarcopenia | Cachexia

Hungary
Hoffmann-La Roche

Completed

RLY-1971 in Subjects With Advanced or Metastatic Solid Tumors

Solid Tumor, Unspecified, Adult

United States
CAGE Bio Inc.
John Peter Smith Hospital

Recruiting

An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection

Fungal Infection | Onychomycosis | Tinea Unguium

United States
Mylan Inc.
Theravance Biopharma

Completed

Thorough QT (TQT) Study of TD-4208 in Healthy Subjects

Cardiac Repolarization in Healthy Subjects

United States
Botanix Pharmaceuticals

Completed

A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

Hyperhidrosis

United States
Forest Laboratories

Completed

Study to Evaluate the Safety and Efficacy of EUR-1008 (APT-1008) Pancreatic Enzyme Product in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Botanix Pharmaceuticals

Completed

A Confirmatory Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

Hyperhidrosis

United States
Bioventus LLC

Terminated

Ultrasound as Adjunct Therapy for Increasing Fusion Success After Lumbar Surgery (EXO-SPINE)

Lumbar Degenerative Disc Disease
Forest Laboratories

Completed

A Randomized, Double-Blind, Dose Response-Control, Crossover Study to Evaluate the Safety and Efficacy of Two Doses of EUR-1008 (APT-1008) in Chronic Pancreatitis (CP) Participants With Exocrine Pancreatic Insufficiency (EPI)

Chronic Pancreatitis | Exocrine Pancreatic Insufficiency

United States, Italy, Ukraine
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Patient-Specific Computational Walking Models in Improving Surgical and Rehabilitation Treatment in Patients With Pelvic Sarcomas

Pelvic Sarcoma

United States
Bioventus LLC
McMaster University; Clinical Advances Through Research and Information Translation

Terminated

Trial to Evaluate UltraSound in the Treatment of Tibial Fractures (TRUST)

Tibial Fractures

United States, Canada
University of Calgary
Bioventus LLC; Workers' Compensation Board, Alberta; Calgary Orthopaedic Research...

Active, not recruiting

Scaphoid Non-union and Low-intensity Pulsed Ultrasound Trial (SNAPU)

Fractures, Ununited | Nonunion of Fracture of Scaphoid Bone

Canada
University Children's Hospital, Zurich

Completed

Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors (FUS-Tumor)

Malignant Brain Tumors

Switzerland
University Children's Hospital, Zurich

Completed

Magnetic Resonance (MR) Guided Functional Ultrasound-Neurosurgery for Movement Disorders

Parkinson's Disease | Dystonia | Essential Tremor

Switzerland
Dong-A ST Co., Ltd.

Unknown

To Investigate the Pharmacokinetics of EPORON® and EPREX® After Subcutaneous Administration in Healthy Male Volunteers

Healthy

Korea, Republic of
Coherent Biopharma (Suzhou) Co., Ltd.

Recruiting

A Study of CBP-1008 in Patients With Advanced Solid Tumor

Advanced Solid Tumor

China
Botanix Pharmaceuticals

Completed

A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

Hyperhidrosis
InSightec

Completed

A Clinical Trial for the Safety and Effect of MRGuided FUS Subthalamotomy for Medication Refractory Parkinson's Disease

Parkinson Disease

Japan
Triple-Gene, LLC
Intrexon Corporation; Precigen, Inc

Completed

Novel INXN-4001 Triple Effector Plasmid in Heart Failure

Cardiovascular Diseases | Heart Failure | Heart-Assist Device

United States
Shin Poong Pharmaceutical Co. Ltd.

Completed

Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SP-8008

Stroke | Acute Coronary Syndrome

United Kingdom
Hill-Rom

Completed

MN4000 for Treatment of CF and MND Patients in the Home Setting

Motor Neuron Disease | Cystic Fibrosis | Airway Clearance Impairment

United States
Diakron Pharmaceuticals

Completed

A Healthy Volunteer Study to Evaluate for a Single Dose of 4 Different Tablets of DPOC-4088 the Absorption and Elimination From the Body and the Potential Effect on Blood Clotting

Deep Vein Thrombosis Leg

Belgium
Lallemand Health Solutions
MedQualis; Q & T Research

Completed

Efficacy of 2 Probiotics During Nicotine Replacement Therapy on Withdrawal Symptoms Associated With Smoking Cessation

Smoking Cessation

Canada
Mexican National Institute of Public Health

Unknown

Supplementation With Vitamin D Improves Leptin Resistance

Obesity | Overweight

Mexico
Replicate Bioscience

Active, not recruiting

A Study of RBI-4000 in Healthy Participants

Healthy Volunteers

United States
InSightec

Active, not recruiting

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

Parkinson Disease

United States, Spain, Taiwan
Mylan Inc.
Theravance Biopharma

Completed

Pharmacokinetics of TD-4208 in Patients With Severe Renal Impairment

Renal Impairment

United States
Diakron Pharmaceuticals
Drug Research Unit Ghent, Ghent, Belgium; Kinesis Pharma B.V.

Terminated

A Healthy Volunteer Study to Investigate the Blood Concentrations, the Effect on Blood Clotting and the Safety of Multiple Doses of DPOC-4088 Tablets in Different Doses.

Deep Vein Thrombosis Leg | Stroke (in Patients With Atrial Fibrillation)

Belgium
Sir Mortimer B. Davis - Jewish General Hospital

Terminated

Two TraCer PositROn EmiSSion Tomography ComBination for Efficacy EstimatiOn of Prostate Specific Membrane Antigen Radioligand Therapy in Patients With Metastatic Prostate Cancer (CROSSBOW)

Prostatic Neoplasms | Prostate Cancer | Metastatic Prostate Cancer | Prostate Adenocarcinoma | Metastatic Prostatic Adenocarcinoma | Metastatic Prostate Carcinoma in the Soft Tissue

Canada
National Cancer Institute (NCI)

Active, not recruiting

Screening for Lung Cancer in Older Patients (PLCO Screening Trial)

Lung Carcinoma

United States
Suzhou Yabao Pharmaceutical R&D Co., Ltd.

Completed

Multiple Ascending Doses of SY-008 in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

China
Senju Pharmaceutical Co., Ltd.
Quotient Sciences

Completed

Single Dose ADME Study of [14C]SJP-0008 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
University of Hawaii
Pennington Biomedical Research Center; United States Department of Agriculture...

Recruiting

mHealth to Improve Diet Quality Among Early Adolescents in SNAP-Ed in Hawaii

Diet, Healthy

United States
Reproductive & Genetic Hospital of CITIC-Xiangya

Recruiting

Recombinant LH Supplementation Timing Strategies (From Day 1 or Day 6) to a Standard GnRH Agonist Long Protocol in Subsequent COS Cycle of Older Patients With Unexpected Poor or Suboptimal Ovarian Response

Infertility,Female

China
Mylan Inc.
Theravance Biopharma

Completed

A 28-Day Parallel Group Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
Daiichi Sankyo, Inc.

Completed

CS1008- in Combination With Sorafenib Compared to Sorafenib Alone in Subjects With Advanced Liver Cancer

Liver Neoplasms | Advanced Hepatocellular Carcinoma | Liver Cancer | Hepatic Cancer

Korea, Republic of, Taiwan, United States, Japan
Forest Laboratories

Completed

Study of Pancreatic Enzyme Product in Pediatric Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

United States
Korea University Anam Hospital

Not yet recruiting

A Clinical Trial to Evaluate the Safety and Efficacy of Neuromodulation Using High Intensity Focused Ultrasound 'ExAblate 4000 Type 2.1' in Patients With Psychostimulant Use Disorder(PUD)

Psychostimulant Use Disorder(PUD)
Korea University Anam Hospital

Not yet recruiting

A Clinical Trial to Evaluate the Initial Safety and Efficacy of Repetitive BBB (Blood Brain Barrier) Disruption Using High Intensity Focused Ultrasound 'ExAblate 4000 Type 2.1' in Patients With Alzheimer's Disease

Alzheimer Disease
Rain Oncology Inc

Terminated

Study for Treatment of Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Skin

Metastatic Head-and-neck Squamous-cell Carcinoma

United States, Australia
Mylan Inc.
Theravance Biopharma

Completed

Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD) (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Mylan Inc.
Theravance Biopharma

Completed

Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD) (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Zoll Medical Corporation

Completed

LifeVest Trends Validation Protocol (TRENDS)

Heart Failure

United States, Germany, Austria
Fujifilm Medical Systems USA, Inc.

Terminated

Pilot Study Comparing Diagnostic Imaging Versus Tomosynthesis in Detection of Hip, Wrist or Tibia Injury (TOMO)

Tibial Fracture | Wrist Injury | Hip Injury

United States
Sanofi

Completed

Immunogenicity of a Split, Cell-Based, Inactivated, Trivalent Influenza Vaccine in Healthy Adult Subjects

Influenza | Myxovirus Infection | Orthomyxoviruses

United States
Medical University of Warsaw

Unknown

Polyethylene Glycol for Childhood Constipation

Constipation

Poland
Assiut University

Not yet recruiting

Congenital Anomalies in Infants of Diabetic Mother

Congenital Abnormalities
Fraser Orthopaedic Research Society

Completed

Proximal Humerus Fracture Dislocation Direction and Avascular Necrosis (PHF-D)

Avascular Necrosis | Proximal Humeral Fracture | Avascular Necrosis of Humerus | Dislocation | Dislocation Shoulder

Canada

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