Search clinical trials for: RTS,S/AS02

Total 3666 results

GlaxoSmithKline

Completed

A Study to Evaluate the Safety and Immunogenicity of GSK Biologicals' Candidate Vaccines RTS,S/AS02D (0.5 mL Dose) and RTS,S/AS02A (0.25 mL Dose) Administered IM According to a 0, 1, 2 Month Vaccination Schedule in Children Aged 3 to 5 Years Living in a Malaria-endemic Region of Mozambique.

Malaria

Mozambique
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Completed

Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,S (MAL019)

Malaria, Falciparum

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline; Walter Reed Army Institute of Research (WRAIR)

Completed

Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults.

Plasmodium Falciparum

Kenya
Michigan State University
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Recruiting

RTSS Vaccine and PBO Net Impact on Malaria Infection and Transmission in Malawi (RTSS/PBO)

Malaria, Malaria Vaccine, Insecticide-treated Bednets

Malawi
GlaxoSmithKline

Completed

Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian Infants

Malaria | Malaria Vaccines

Tanzania
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Malaria Vaccine RTS,S/AS02A, When Administered to Children Aged 1 to 4 Years Living in a Malaria-endemic Region of Mozambique.

Malaria

Mozambique
University of Oxford
National Institute for Health Research, United Kingdom; The PATH Malaria Vaccine...

Completed

A Safety and Efficacy Study of Concomitant Administration of ChAd63/MVA ME-TRAP + RTS,S

Plasmodium Falciparum Malaria

United Kingdom
U.S. Army Medical Research and Development Command
GlaxoSmithKline; Walter Reed Army Institute of Research (WRAIR)

Completed

Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria

Malaria

United States
GlaxoSmithKline

Completed

Examine Safety and Immune Responses of GSK 257049 Vaccine When Administered to Infants Living in a Malaria-endemic Region

Malaria

Mozambique
London School of Hygiene and Tropical Medicine
Malaria Research and Training Center, Bamako, Mali; Institut de Recherche en...

Completed

Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) (RTSS-SMC)

Children, Only | Malaria,Falciparum

Burkina Faso, Mali
University of Oxford

Completed

Malaria Vaccine Safety and Immunogenicity Study in Healthy Adults (RTSS)

Malaria Vaccine

Thailand
London School of Hygiene and Tropical Medicine
Malaria Research and Training Center, Bamako, Mali; Institut de Recherche en...

Completed

Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension Study (RTSS-SMC)

Child, Only | Malaria,Falciparum

Mali, Burkina Faso
GlaxoSmithKline

Completed

A Study to Evaluate the Reactogenicity, Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Investigational Supra-seasonal Universal Influenza Vaccines - Inactivated (SUIVs) (GSK3816302A) in Healthy Adults Aged 18 to 39 Years

Influenza, Human

United States, Belgium
GlaxoSmithKline
The PATH Malaria Vaccine Initiative (MVI)

Completed

Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults

Malaria

United States
GlaxoSmithKline

Completed

Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age

Malaria

Ghana, Kenya
GlaxoSmithKline
PATH

Completed

A Study to Evaluate the Efficacy, Immunogenicity and Safety in a Sporozoite Challenge Model of a Fractional Booster Dose of GSK Biologicals' Candidate Malaria Vaccine Administered to Previously Vaccinated Healthy Malaria-naïve Adults

Malaria

United States
University of Oxford

Completed

A Safety and Efficacy Study of ChAd63/MVA METRAP + RTS,S

Plasmodium Falciparum Malaria

United Kingdom
PATH
GlaxoSmithKline; Kenya Medical Research Institute; US Army Medical Research Directorate-Africa... and other collaborators

Completed

RTS,S/AS01E Hypo-immuno-responsiveness Study

Plasmodium Falciparum

Kenya
GlaxoSmithKline
Walter Reed Army Institute of Research (WRAIR); The PATH Malaria Vaccine Initiative...

Completed

Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve Adults

Malaria

United States
Labdom Suisse

Unknown

Medical Radiometer - RTM - 01 - RES and Its Use in Detecting Hotspots in Female Breast (RTM)

Breast Cancer

Malaysia
GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02 in Healthy PPD-negative Adults.

Tuberculosis (TB)

Belgium
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Completed

Switching to Low Oxidant Content Cigarettes in Adult Smokers

Oxidative Stress | Nicotine

United States
M.D. Anderson Cancer Center
Concordia Pharmaceuticals, Inc

Completed

FTS Study in Patients With Advanced Hematologic Malignancies

Leukemia | Myelodysplastic Syndrome

United States
KEMRI-Wellcome Trust Collaborative Research Program
GlaxoSmithKline

Unknown

An Extended Follow up of a RTS,S/AS01E Malaria Vaccine Trial (MAL059)

Malaria

Kenya
Affiris AG

Completed

Clinical- and Immunological Activity, Safety and Tolerability of Different Doses / Formulations of AFFITOPE AD02 in Early Alzheimer's Disease

Alzheimer's Disease

France, Austria, Croatia, Germany, Czech Republic, Slovakia
SK Bioscience Co., Ltd.
GlaxoSmithKline; International Vaccine Institute; Coalition for Epidemic Preparedness...

Completed

Immunogenicity and Safety Study of SK SARS-CoV-2 Recombinant Nanoparticle Vaccine (GBP510) Adjuvanted With AS03 (COVID-19)

Covid19

Thailand, Korea, Republic of, New Zealand, Philippines, Ukraine, Vietnam
GlaxoSmithKline

Completed

Partially-blind (Observer-blind) Study of Safety and Immunogenicity of Two Malaria Vaccines in Ghanaian Children

Malaria

Ghana
Affiris AG

Terminated

Follow-up Study to Assess Safety and Clinical Activity of Continued AFFITOPE® AD02 Vaccinations of Patients Who Participated in AFF006

Alzheimer´s Disease

France, Austria, Croatia, Czech Republic, Germany, Slovakia
Sun Pharmaceutical Industries Limited

Completed

Efficacy and Safety of AS012 in Subjects With Non-segmental Vitiligo

Non-segmental Vitiligo

United States, India
National Institute of Allergy and Infectious Diseases...

Completed

An Investigational Combination Vaccine Given to People Who Are Not Infected With HIV

HIV Infections

United States
HK inno.N Corporation

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetic Properties of IN-A002 Ointment in Healthy Adult Male Volunteers and Mild to Moderate Atopic Dermatitis Patients

Mild to Moderate Atopic Dermatitis
Centre for Addiction and Mental Health

Completed

rTMS and Cognitive Training in Youth Depression

Depression

Canada
GlaxoSmithKline

Completed

Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children.

Malaria

Kenya, Tanzania
University Hospital, Strasbourg, France

Active, not recruiting

Personalized Non-invasive Neuromodulation by rTMS for Chronic and Treatment Resistant Catatonia (RETONIC)

Schizophreniform Catatonia | Treatment Resistant

France
GlaxoSmithKline

Completed

Human Papilloma Virus Vaccine Immunogenicity and Safety Trial in Young Adult Women With GSK Bio's Novel HPV Vaccine.

Infections, Papillomavirus

Belgium, United States
Shiga University
University of Chicago; Shionogi; Tokyo University; Showa University; Fukushima Medical... and other collaborators

Unknown

Phase II Study of S-488410 to Treat Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Japan
GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02A in Healthy PPD-positive Adults

Tuberculosis (TB)

Switzerland
PATH
GlaxoSmithKline; Icahn School of Medicine at Mount Sinai; Duke University; Children... and other collaborators

Completed

Safety and Immunogenicity of a Live-attenuated Universal Flu Vaccine Followed by an Inactivated Universal Flu Vaccine

Influenza | Vaccine

United States
Diana Trang

Terminated

Frequency Specific Microcurrent for the Treatment of Diastasis Recti

Diastasis Recti

United States
University Hospital, Toulouse

Completed

Combined Deep Brain Stimulation in Parkinson's Disease (SCP-FOG)

Parkinson Disease

France
Boston Scientific Corporation

Completed

Boston Scientific Post Market S-ICD Registry (EFFORTLESS)

Tachycardia, Ventricular

United Kingdom, Denmark, Italy, New Zealand, Germany, France, Netherlands, Portugal, Czechia, Spain
Alaunos Therapeutics

Completed

Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102

Glioblastoma

United States
Henogen
GlaxoSmithKline

Completed

Compare the Immune Response & Safety Elicited by Henogen's Adjuvanted Hepatitis B Vaccine vs Aventis Pasteur MSD's Hepatitis B Vaccine in Pre-Dialysis & Dialysis Patients Who Did Not Respond to Previous Hepatitis B Vaccination

Hepatitis B

Belgium, Czech Republic, Hungary
Shionogi

Completed

First-in-human Study of S-588210 (S-488210+S-488211)

Head and Neck Cancer | Esophageal Cancer | Lung Cancer | Mesothelioma | Bladder Cancer

United Kingdom
University of Nebraska Lincoln
Centers for Disease Control and Prevention; The Set Me Free Project; Des Moines...

Recruiting

Preventing Commercial Sexual Exploitation of Children (Project LIVE)

Sexual Violence | Sex Trafficking | Child Abuse, Sexual | Sex Crimes | Commercial Sex | Sex Offense

United States
J Ints Bio

Recruiting

A Phase 1/2 Study to Evaluate the Safety, Tolerability and PK of JIN-A02 in Patients With EGFR Mutant Advanced NSCLC

EGFR Mutant Advanced Non-small Cell Lung Cancer

Korea, Republic of, United States, Thailand
Affiris AG

Completed

Safety/Tolerability, Immunological and Clinical Activity of a Boost Immunization With AFFITOPE AD02

Alzheimer's Disease

Austria
Affiris AG

Completed

Tolerability and Safety of Subcutaneous Administration of AFFITOPE AD02 in Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Austria
The University of Texas Medical Branch, Galveston
Medicem International CR s.r.o.

Completed

Comparing Outpatient to Inpatient Cervical Ripening Using Dilapan-S® (HOMECARE)

Labor, Induced | Cervix Uteri-Diseases

United States
Kyowa Kirin Co., Ltd.

Terminated

Study of KHK 4323 in Healthy Volunteers and Subjects With Atopic Dermatitis

Atopic Dermatitis

Japan

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