Search clinical trials for: Recombinant Human Plasminogen Activator (HTUPA)

Total 1524 results

Tasly Biopharmaceuticals Co., Ltd.

Completed

Study of rhPro-UK in Patients With Acute Ischaemic Stroke in 4.5 Hours After Stroke Onset(PROST)

Acute Ischaemic Stroke

China
Novo Nordisk A/S

Completed

Safety and Preliminary Efficacy of Activated Recombinant Human Factor VII in Acute Intracerebral Haemorrhage

Acquired Bleeding Disorder | Intracerebral Haemorrhage

Finland, Singapore, Australia, Spain, Denmark, Germany, Italy, Taiwan, United Kingdom
Tongji Hospital

Unknown

Dose-effect Relationship of Rt-PA on ICH Evacuation

Hypertensive Intracerebral Hemorrhage

China
Boehringer Ingelheim

Completed

Temporal Trends of Thrombolysis Treatment in Chinese Acute Ischemic Stroke (AIS) Patients From 2007-2017: Analysis of China National Stroke Registry (CNSR) I, II, and III; CTP-Draft Review Performed;

Stroke

China
Boston Scientific Corporation
EKOS Corporation

Completed

Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy (SEATTLE II)

Pulmonary Embolism | Acute Pulmonary Embolism | Pulmonary Thromboembolism | Massive Pulmonary Embolism | Sub-massive Pulmonary Embolism

United States
Novo Nordisk A/S

Completed

Safety and Tolerability of Intravenous Doses of Activated Recombinant Human Factor VII in Healthy Volunteers

Healthy | Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

France
Novo Nordisk A/S

Completed

Safety and Preliminary Efficacy of Activated Recombinant Human Factor VII for Preventing Early Hematoma Growth in Acute Intracerebral Haemorrhage

Acquired Bleeding Disorder | Intracerebral Haemorrhage

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Activated Recombinant Human Factor VII in Severely Injured Trauma Patients

Trauma | Acquired Bleeding Disorder

Germany, Austria, Israel, France, Canada, Singapore, South Africa, Australia, United Kingdom
Alexandria University

Completed

Direct Mechanical Thrombectomy Versus Bridging Therapy

Ischemic Stroke | Thrombectomy | Large-Artery Atherosclerosis (Embolus/Thrombosis)

Egypt
Boston Scientific Corporation
EKOS Corporation

Completed

Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Pulmonary Embolism (OPTALYSE PE)

Pulmonary Embolism and Thrombosis

United States, United Kingdom
Novo Nordisk A/S

Completed

Observational Study on the Efficacy and Safety of NovoSeven® During "Real-life" Usage in Germany (WIRK)

Congenital Bleeding Disorder | Acquired Bleeding Disorder | Acquired Haemophilia | Congenital FVII Deficiency | Glanzmann's Disease

Germany
Tasly Biopharmaceuticals Co., Ltd.

Completed

A Trial in Recombinant Human Prourokinase to Treat Acute Pulmonary Embolism (ERUPTE)

Acute Pulmonary Embolism

China
Universitaire Ziekenhuizen KU Leuven

Withdrawn

Surgical Stabilizer Assisted RVC With rtPA for CRVO

Central Retinal Vein Occlusion

Belgium
University Hospital Inselspital, Berne
Medtronic

Completed

Bridging Thrombolysis Versus Direct Mechanical Thrombectomy in Acute Ischemic Stroke (SWIFT DIRECT)

Ischemic Stroke

Spain, France, Germany, Canada, United Kingdom, Austria, Finland, Switzerland
Northwestern University
National Cancer Institute (NCI)

Completed

In Vivo Angiostatin Generation Using Tissue Plasminogen Activator and Captopril in Treating Patients With Progressive Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Activated Recombinant Human Factor VII in Treatment of Bleeding in Patients Following Allogeneic Stem Cell Transplantation

Acquired Bleeding Disorder | Bleeding During/Following Surgery

Israel, Sweden, United Kingdom, Germany, Switzerland, France, Spain, Italy, Thailand, Denmark, United States, Poland, Finland, Singapore, Australia, Austria
University of California, San Diego
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke

Stroke

United States
Novo Nordisk A/S

Terminated

Efficacy and Safety of Activated Recombinant Human Factor VII in Treatment of Bleeding in Patients Following Hematopoietic Stem Cell Transplantation

Acquired Bleeding Disorder | Bleeding During/Following Surgery

United States
Novo Nordisk A/S

Completed

A Single Dose Trial Investigating Safety and Local Tolerability of Ascending Doses of Long Acting Activated Recombinant Human Factor VII in Healthy Male Volunteers

Healthy | Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Beijing Chao Yang Hospital
Ministry of Science and Technology of the People´s Republic of China

Unknown

Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD

Pulmonary Embolism | Pulmonary Thromboembolisms

China
Novo Nordisk A/S

Completed

Observational Registry of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors (ONE)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Saudi Arabia, Algeria, Turkey, Germany, Poland, Netherlands, Italy, Belgium, South Africa, United Kingdom, Sweden, Austria, Portugal, France, Czech Republic, Venezuela
Novo Nordisk A/S

Completed

Post-marketing Safety Surveillance of NovoSeven® in Patients With Haemophilia and Inhibitors by Means of the UK Haemophilia Database

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Myocardial Infarction Triage and Intervention Project (MITI)

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease
Population Health Research Institute
Heart and Stroke Foundation of Canada

Recruiting

Adjunctive, Low-dose tPA in Primary PCI for STEMI (STRIVE)

Myocardial Infarction | Percutaneous Coronary Intervention

Canada
Novo Nordisk A/S

Completed

Prediction of the Efficacy of Activated Recombinant Human Factor VII in Adult Congenital Haemophilia A or B Patients With Inhibitors by Use of Thromboelastography

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

United States, Denmark, France, United Kingdom
Novo Nordisk A/S

Completed

PROPACT: Retrospective Prophylaxis Patient Case Collection (PROPACT)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Slovakia, Spain, Argentina, Germany, Croatia, Italy, Canada, United Kingdom, Ireland, Sweden, France, United States, Czech Republic, Switzerland
Azienda U.S.L. 1 di Massa e Carrara

Withdrawn

Efficacy and Safety of Half Dose Alteplase Added to Heparine, in Patients With Moderate Pulmonary Embolism (MONALYSE)

Pulmonary Embolism
General Hospital of Shenyang Military Region

Completed

EXtending the tIme Window of Thrombolysis by ButyphThalide up to 6 Hours After Onset (EXIT-BT)

Stroke, Ischemic

China
Assiut University
Aswan University Hospital

Completed

TPA in Acute Stroke With COVID Verus Non-COVID-19 Patients (rTPA)

Acute Ischemic Stroke

Egypt
Novo Nordisk A/S

Completed

Pharmacokinetics of Single Bolus Dose of NovoSeven® in Paediatric and Adult Patients With Haemophilia A or B in a Non- Bleeding State

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

Spain, Italy, Greece, Germany, United Kingdom
Novo Nordisk A/S

Completed

Observational Registry of the Treatment of Glanzmann's Thrombasthenia

Congenital Bleeding Disorder | Glanzmann's Disease

Spain, Bulgaria, Pakistan, Belgium, Germany, France, United Kingdom, Italy, Hungary, Netherlands, United States, Algeria, Austria, Sweden, Switzerland
Novo Nordisk A/S

Completed

Observational Study Describing the Usual Clinical Practice Use of NovoSeven® in the Home Treatment of Joint Bleeds in Patients With Haemophilia A or B and Inhibitors

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

Morocco, United Arab Emirates, Algeria, Oman, Saudi Arabia
Assiut University

Unknown

Regisry of the Stroke Patients in Assiut University Hospital

All Patients With Ischemic Cerebrovascular Stroke Aged ≥18 Years of Both Sex
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Thrombolysis in Myocardial Ischemia Trial (TIMI III)

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Angina Pectoris
Novo Nordisk A/S

Completed

Observational Study on the Use of NovoSeven® for Haemostatic Treatment of Bleeding Episodes in Patients With Acquired Haemophilia (ACQUI-7)

Acquired Bleeding Disorder | Acquired Haemophilia

France
Novo Nordisk A/S

Completed

Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

France, United States, Spain, Brazil, Philippines, South Africa, Poland, Turkey, Romania, Bulgaria, Russian Federation, Argentina
Novo Nordisk A/S

Completed

Observational Study on Safety of Room Temperature Stable NovoSeven® in Patients With Haemophilia A or B

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

Belgium, Germany, France, United Kingdom, Italy, Hungary, Austria, Sweden, Iran, Islamic Republic of, Argentina, Ireland, Poland, Portugal, Slovakia
Eastern Regional Medical Center

Recruiting

Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions

Loculated or Non-draining Malignant Pleural Effusions

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Thrombolysis in Myocardial Infarction (TIMI)

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease
Second Affiliated Hospital, School of Medicine,...

Recruiting

EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs

Stroke, Acute Ischemic

China
Neuroscience Trials Australia
China Medical University Hospital

Completed

EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) (EXTEND)

Stroke

Taiwan
Kyorin University

Completed

Submacular Hemorrhage Associated With Retinal Arterial Macro Aneurysm

Submacular Hemorrhage | Ruptured Retinal Arterial Macro Aneurysms

Japan
Yale University

Withdrawn

The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.

Pleural Effusion | Cancer, Lung
Seattle Children's Hospital
The Hospital for Sick Children; Medical College of Wisconsin; McMaster University and other collaborators

Terminated

Thrombolysis in Pediatric Stroke (TIPS) (TIPS)

Stroke

United States, Canada
South West Sydney Local Health District

Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure (VETtiPAT-ARF)

Acute Respiratory Failure | Hypercoagulability | Fibrinolysis Shutdown

Australia
Melbourne Health

Completed

Tenecteplase Versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (TASTEa)

Stroke, Acute, Stroke Ischemic

Australia
Neuroscience Trials Australia
Melbourne Health; University of Melbourne; Commonwealth Scientific and Industrial... and other collaborators

Completed

Extending the Time for Thrombolysis in Emergency Neurological Deficits (EXTEND)

Stroke

Australia, Finland, New Zealand
Kartal Kosuyolu Yuksek Ihtisas Education and Research...

Completed

Comparison of Different TRansesophageal Echocardiography Guided thrOmbolytic Regimens for prosthetIc vAlve Thrombosis (TROIA)

Prosthetic Valve Thrombosis

Turkey
Novo Nordisk A/S

Completed

Safety and Efficacy of Activated Recombinant Human Factor VII in Patients Undergoing Orthotopic Liver Transplantation

Acquired Bleeding Disorder | Bleeding During/Following Surgery

Germany, Sweden, United Kingdom, Spain, Canada, Australia, France
Novo Nordisk A/S

Completed

Safety and Efficacy of Activated Recombinant Human Factor VII in Cirrhotic Patients Undergoing Partial Hepatectomy

Cirrhosis | Acquired Bleeding Disorder

Taiwan, Thailand, China

Search clinical trials for: Recombinant Human Plasminogen Activator (HTUPA)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Lithuania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations