Search clinical trials for: recombinant human interleukin-2 (rhIL-2)

Total 973 results

National Cancer Institute (NCI)

Terminated

Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer

Metastatic Melanoma | Metastatic Renal Cancer

United States
University Hospital, Basel, Switzerland

Active, not recruiting

Empagliflozin and Anakinra for the Treatment of Postprandial Hypoglycemia in Patients With Prediabetes (Hypo-PrEA)

Postprandial Hypoglycemia

Switzerland
Philogen S.p.A.

Terminated

A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Diffuse Large B-cell Lymphoma (DLBCL)

Germany
M.D. Anderson Cancer Center

Completed

Cisplatin, Temozolomide, Abraxane, With Interleukin-2 and Interferon for Metastatic Melanoma (BCAA)

Melanoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); AstraZeneca; Juno Therapeutics, Inc.; MedImmune...

Terminated

JCAR014 and Durvalumab in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

United States
University Medical Center Groningen

Terminated

IL2 Imaging in Metastatic Melanoma

Melanoma

Netherlands
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Pegylated Interferon Alfa-2b Versus Interferon Alfa Therapy in Adult Essential Thrombocythemia

Essential Thrombocytopenia

China
St. Anna Kinderkrebsforschung

Recruiting

High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN)

Neuroblastoma

Norway, Czechia, United Kingdom, France, Spain, Belgium, Switzerland, Hungary, Israel, Australia, Italy, Austria, Denmark, Greece, Ireland, Poland, Portugal, Slovakia, Slovenia, Sweden
St George's, University of London

Unknown

Study of Single IV Administration of P2G12 (FuturePharma)

HIV Infection

United Kingdom
Beijing Bio-Fortune Ltd.

Completed

Recombinant Human Serum Albumin/Interferon alpha2a Fusion Protein Phase Ib Study in Chronic Hepatitis B Patients

Chronic Hepatitis B

China
M.D. Anderson Cancer Center
Bristol-Myers Squibb

Terminated

IPI Biochemotherapy for Chemonaive Patients With Metastatic Melanoma

Melanoma

United States
Inge Marie Svane

Completed

Vemurafenib and TIL Therapy for Metastatic Melanoma

Metastatic Melanoma

Denmark
Inge Marie Svane

Unknown

TIL Therapy for Metastatic Renal Cell Carcinoma

Metastatic Renal Cell Carcinoma

Denmark
University of Aarhus
Danish Renal Cancer Study Group

Unknown

Study of Interleukin-2, Interferon-alpha and Bevacizumab in Metastatic Kidney Cancer

Metastatic Renal Cell Carcinoma

Denmark
Sanofi Pasteur, a Sanofi Company

Completed

Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adults in Thaïland

Rabies (Healthy Volunteers)

Thailand
St. Anna Kinderkrebsforschung
Centre Leon Berard; Medical University of Graz; Fondazione IRCCS Istituto Nazionale... and other collaborators

Unknown

Long Term Continuous Infusion ch14.18/CHO Plus s.c. Aldesleukin (IL-2) (LTI)

Neuroblastoma

France, Spain, Austria, Germany, Israel, Italy, United Kingdom
National Cancer Institute (NCI)

Terminated

Vaccine Treatment of Kidney Cancer

Kidney Cancer

United States
University of Washington

Terminated

Continuous Infusion Chemotherapy (CI-CLAM) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myeloid Neoplasm

United States
National Cancer Institute (NCI)

Completed

R-(-)-Gossypol Acetic Acid in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer

United States
HanAll BioPharma Co., Ltd.

Completed

A Phase 1b/2a, Open-label,Randomized, Safety, Tolerability, Dose Finding, PK/PD, and Preliminary Efficacy Study of SC Hanferon™ in Combination With Ribavirin in Treatment-naïve Subjects With Genotype 1 Hepatitis C

Chronic Hepatitis C Infection | Genotype 1

United States
Jorge A. Garcia, MD
National Cancer Institute (NCI)

Completed

Bevacizumab and Aldesleukin in Treating Patients With Metastatic Clear Cell Carcinoma of the Kidney

Kidney Cancer

United States
Tianjin SinoBiotech Ltd.

Completed

Study of Recombinant Human Serum Albumin/Interferon alpha2b Fusion Protein in Chinese Healthy Volunteers

Healthy

China
University of Alabama at Birmingham

Terminated

Pilot Study of Zoledronic Acid and Interleukin-2 for Refractory Pediatric Neuroblastoma

Neuroblastoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
Vastra Gotaland Region

Not yet recruiting

Locoregional Administration of TIL and Lymphodepletion in Patients With Melanoma and Liver Metastases (HAITILS-PHP)

Metastatic Cutaneous Melanoma | Uveal Melanoma
Goethe University

Active, not recruiting

Capecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Cancer Patients (ACO/ARO/AIO-21)

Rectal Cancer

Germany
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Recurrent High Risk Myelodysplastic Syndrome | Refractory High Risk Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia

United States
Vastra Gotaland Region
Miltenyi Biomedicine GmbH

Recruiting

Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases (HAITILS)

Metastatic Cutaneous Melanoma | Metastatic Uveal Melanoma

Sweden
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Pegylated Interferon Alfa-2b Versus Interferon Alfa Therapy in Childhood and Adolescent Essential Thrombocythemia

Essential Thrombocytopenia

China
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immunogenicity of Priming With Live Attenuated A/H7N9 Influenza Virus Vaccine Followed By Inactivated A/H7N9 Influenza Virus Vaccine With AS03 Adjuvant

Influenza A Virus, H7N9 Subtype

United States
Tianjin SinoBiotech Ltd.

Completed

Study of Recombinant Human Serum Albumin/Interferon alpha2b Fusion Protein in Hepatitis B Patient

Hepatitis B Virus

China
Intima Bioscience, Inc.

Not yet recruiting

CISH Inactivated TILs in the Treatment of NSCLC (CheckCell-2)

Carcinoma, Non-Small-Cell Lung | Adenocarcinoma of Lung | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Metastatic Non Small Cell Lung Cancer | Large Cell Lung Cancer

United States
Vastra Gotaland Region
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden; Nordic...

Unknown

A Study of HDC/IL-2 Treatment in Chronic Myelomonocytic Leukemia (CMML)

Leukemia, Myelomonocytic, Chronic

Sweden
National Cancer Institute (NCI)

Withdrawn

Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Recurrent Childhood Acute Myeloid Leukemia | CNS 2a | CNS 2b | CNS 2c | CNS1
Benha University

Completed

Double J Stenting and Sildosin After URSL for Lower Ureteric Stones (DJ)

Lower Ureteric Stones | Ureteroscopic Lithotripsy | DJ Stenting

Egypt
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); Novartis; Lymphoma Research Foundation

Completed

Universal Granulocyte Macrophage-colony Stimulating Factor (GM-CSF)-Producing and GM.CD40L for Autologous Tumor Vaccine in Mantle Cell Lymphoma

Lymphoma

United States
Vall d'Hebron Institute of Oncology
Banc de Sang i Teixits

Recruiting

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors (NEXTGENTIL-ACT)

Epithelial Tumors, Malignant | Malignant Solid Tumor

Spain
University of Arkansas

Completed

Study of KIR-Ligand Mismatched Haplo-Identical Natural Killer Cells Transfused Before Autologous Stem Cell Transplant

Multiple Myeloma

United States
Novartis Pharmaceuticals

Recruiting

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

FLT3-mutated Acute Myeloid Leukemia

Korea, Republic of, Germany, Italy, Turkey, Czechia, Jordan, Slovenia, Austria, Poland, Japan, Russian Federation, United States, Greece
Masonic Cancer Center, University of Minnesota

Completed

Donor Natural Killer Cells and Aldesleukin in Treating Patients w/High Risk AML Undergoing Donor Stem Cell Transplant

Acute Myelogenous Leukemia

United States
Philogen S.p.A.
Merck Sharp & Dohme LLC

Active, not recruiting

Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination With Pembrolizumab, in Unresectable Melanoma Patients (INTACT/MeRCI)

Melanoma Stage IV | Melanoma Stage III

United States
Gilead Sciences

Terminated

Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers

Human Papillomavirus (HPV) 16+ Relapsed/Refractory Cancer

United States
Centre Hospitalier Universitaire Vaudois

Terminated

Adoptive Transfer Of Autologous Tumor-Infiltrating Lymphocytes in Solid Tumors

Solid Tumor, Adult

Switzerland
M.D. Anderson Cancer Center

Terminated

Biochemotherapy With Temozolomide for Metastatic Melanoma

Melanoma

United States
Centre Hospitalier Universitaire Vaudois

Active, not recruiting

NeoTIL in Advanced Solid Tumors

Solid Tumor, Adult

Switzerland
University of Washington
AbbVie

Suspended

Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Refractory Mixed Phenotype Acute Leukemia | Myeloid Neoplasm | Acute Biphenotypic Leukemia | Refractory Acute Biphenotypic Leukemia | Relapsed Acute Myeloid Leukemia | Mixed Phenotype Acute Leukemia | Relapsed Acute Biphenotypic Leukemia | Relapsed... and other conditions

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI); NCIC Clinical Trials Group; Children's Oncology... and other collaborators

Active, not recruiting

High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma

Melanoma (Skin)

United States, Canada, Australia, South Africa
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma That Has Not Responded to Previous Treatment

Melanoma (Skin)

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ofatumumab, Pentostatin, and Cyclophosphamide in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Chronic Lymphocytic Leukemia | Stage III Small Lymphocytic Lymphoma | Stage IV Small Lymphocytic Lymphoma | Stage 0 Chronic Lymphocytic Leukemia | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Stage I Small Lymphocytic Lymphoma | Stage III Chronic Lymphocytic Leukemia and other conditions

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of CYD Dengue Vaccine in Healthy Children and Adolescents in South America

Dengue | Dengue Hemorrhagic Fever

Brazil

Search clinical trials for: recombinant human interleukin-2 (rhIL-2)

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