Search clinical trials for: Reference Drug

Total 256261 results

Gruppo Italiano per lo studio dei Carcinomi dell...
Mario Negri Institute for Pharmacological Research

Unknown

Metastatic Advanced Pancreas Sorafenib (MAPS)

Locally Advanced Pancreatic Cancer

Italy
Glaxo Wellcome

Completed

Safety and Effectiveness of a Combination Anti-HIV Drug Treatment

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 in Combination With Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Ohio State University Comprehensive Cancer Center

Not yet recruiting

A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients

Low Anterior Resection Syndrome | Rectal Carcinoma

United States
Abramson Cancer Center at Penn Medicine

Not yet recruiting

FAPI-74 PET/CT in Adults With Fibrosis

Fibrosis (Morphologic Abnormality)

United States
World Health Organization
London School of Hygiene and Tropical Medicine; University of Ghana; Biomedical... and other collaborators

Recruiting

An Adolescent Health and Wellbeing Check-up Programme in Three African Cities (Y-Check) (Y-Check)

Health-Related Behavior | Adolescent Behavior | Adolescent Development | Health Care Seeking Behavior

Ghana, Tanzania, Zimbabwe
Inari Medical

Recruiting

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis (DEFIANCE)

Venous Thromboembolism | Deep Venous Thrombosis | Post-Thrombotic Syndrome

United States, Germany, Finland, Switzerland, United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

An Investigational Scan (68Ga-FAPI-46 PET/CT) for the Imaging of Cancer-Associated Fibroblasts in Patients With Localized Pancreatic Ductal Adenocarcinoma

Stage 0 Pancreatic Cancer AJCC v8 | Stage I Pancreatic Cancer AJCC v8 | Stage IIA Pancreatic Cancer AJCC v8 | Resectable Pancreatic Ductal Adenocarcinoma | Localized Pancreatic Adenocarcinoma

United States
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

Ovarian Endometrioid Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube High Grade Serous Adenocarcinoma | Primary Peritoneal Endometrioid Adenocarcinoma | Stage III Fallopian... and other conditions

United States
Susan Chang
GE Healthcare; Sigma-Aldrich; Phillips-Medisize

Recruiting

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Recurrent WHO Grade III Glioma | WHO Grade III Glioma | WHO Grade II Glioma | Recurrent World Health Organization (WHO) Grade II Glioma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Collecting Information About Treatment Results for Patients With Cushing's Syndrome

Cushing Syndrome | Cushing's Disease | Cushing Disease

United States
St. Joseph's Hospital and Medical Center, Phoenix
The Cleveland Clinic; Thomas Jefferson University

Recruiting

Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions (POET)

Pituitary Adenoma | Antibiotics

United States
Ain Shams University

Completed

Efficacy of Vonoprazan in Eradication of Resistant Strain of Helicobacter Pylori

Helicobacter Pylori Infection

Egypt
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
The Crofoot Research Center, Inc.
Janssen Scientific Affairs, LLC

Completed

Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART) (ReSTART)

HIV-1-infection

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer

Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapy

Invasive Breast Carcinoma | HER2/Neu Negative | Bilateral Breast Carcinoma

United States
Bristol-Myers Squibb

Active, not recruiting

A Study to Evaluate the Safety and Tolerability of BMS-986408 Alone and in Combination With Nivolumab or Nivolumab and Ipilimumab in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Canada, United States, Spain, France, Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Acute Bilineal Leukemia and other conditions

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Spain, United Kingdom, New Zealand, Israel, Australia, Ireland, Germany, Sweden, Czechia, Portugal, Hungary
Daniel M. Spielman
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

Malignant Central Nervous System Neoplasm | Metastatic Malignant Neoplasm in the Central Nervous System

United States
Fundação Bahiana de Infectologia

Completed

Impact of a Dolutegravir-based Regimen on Early Mortality of AIDS Patients (IDEA)

Severely Immunocompromised HIV Patients

Brazil
National Cancer Center, Korea

Active, not recruiting

Effects of H. Pylori Eradication on the Gastric Preneoplastic Lesion and Neoplasm After ESD

Early Gastric Cancer | Helicobacter Pylori Infection | Endoscopic Resection

Korea, Republic of
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Active, not recruiting

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Oropharyngeal Human Papillomavirus-Positive Squamous...

United States
Ain Shams University

Completed

Potassium Copetitive Acid Blockers Efficacy in H.Pylori Eradication (P-CABs)

Helicobacter Pylori Eradication

Egypt
Northwell Health

Completed

Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy

Kidney Stones

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gallium Ga 68-DOTATATE PET/CT in Predicting Tumor Growth in Patients With Meningiomas

Meningioma

United States
Portola Pharmaceuticals

Completed

A Healthy Volunteer PK/PD, Safety and Tolerability Study of Second Generation Andexanet Alfa

Bleeding

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; National Cancer Institute (NCI); Candel Therapeutics, Inc.

Active, not recruiting

GMCI, Nivolumab, and Radiation Therapy in Treating Patients With Newly Diagnosed High-Grade Gliomas (GMCI)

Glioma, Malignant

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); AIDS Associated Malignancies Clinical Trials...

Completed

Paclitaxel in Treating Patients With AIDS-Related Kaposi's Sarcoma

Sarcoma

United States
Novavax
Coalition for Epidemic Preparedness Innovations

Completed

Evaluation of the Safety and Immunogenicity of a SARS-CoV-2 rS Nanoparticle Vaccine With/Without Matrix-M Adjuvant

COVID-19

United States, Australia
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

First in Human Study of M4344 in Participants With Advanced Solid Tumors

Solid Tumor | Advanced Solid Tumor

Spain, United States, Netherlands, United Kingdom
Nektar Therapeutics

Terminated

Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors (PROPEL)

Non-Small Cell Lung Cancer

United States, Germany, Spain, Australia, France
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Fordham University

Completed

Trial of Individual Psychosocial Interventions for Cancer Patients

Advanced Solid Tumor Diseases

United States
Johns Hopkins Bloomberg School of Public Health
Bill and Melinda Gates Foundation; Direct Consulting and Logistics

Completed

Tunatar da ni. The Immunization Reminder and Information SMS System (IRISS) (IRISS)

Low Immunization Uptake

Nigeria
Actelion

Completed

A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants

Healthy

Belgium
OHSU Knight Cancer Institute
Oregon Health and Science University

Completed

Steady State Blood Volume Maps Using Ferumoxytol Non-stoichiometric Magnetite MRI in Imaging Patients With Glioblastoma

Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Sorafenib With or Without Paclitaxel and Carboplatin in Treating Patients With Recurrent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Anti-HIV Drug Regimens and Treatment-Switching Guidelines in HIV Infected Children

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Cyclosporine A in Combination With Abacavir Sulfate, Lamivudine, and Zidovudine and Lopinavir/Ritonavir in HIV

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety, Tolerability, and Anti-HIV Activity of DMP 266 (Efavirenz) in Combination With Nelfinavir in HIV-Positive Children

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study to Compare Two Different Anti-HIV Drug Regimens

HIV Infections

United States, Puerto Rico
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Rifampicin on the Pharmacokinetics of SHR6390 in Healthy Subjects

Healthy Subjects

China
Wroclaw Medical University

Completed

Mental Simulations and Early Mobilization of Patients After Cesarean Section

Anxiety | Cesarean Section

Poland
University of Colorado, Denver
Cystic Fibrosis Foundation; Colorado Clinical & Translational Sciences Institute

Completed

Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis

Cystic Fibrosis

United States
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Cryptococcal Optimal ART Timing Trial (COAT)

HIV Infections | AIDS | Cryptococcal Meningitis

Uganda, South Africa
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer

Lung Adenocarcinoma | Minimally Invasive Lung Adenocarcinoma | Malignant Pleural Effusion | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage IV Lung Non-Small Cell Cancer AJCC v7 | Malignant Pericardial Effusion | Lung Adenosquamous Carcinoma

United States
Fundación Pública Andaluza para la Investigación...
Merck Sharp & Dohme LLC

Unknown

Raltegravir One Thousand Two Hundred vs Darunavir-cb in Immnunosupressed Patients: ROTDIP Study (ROTDIP)

HIV Infections
National University Hospital, Singapore
Singapore General Hospital; Tan Tock Seng Hospital

Completed

Antibiotics for Klebsiella Liver Abscess Study

Liver Abscess, Pyogenic

Singapore

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