Search clinical trials for: Reference Drug

Total 256958 results

First Affiliated Hospital of Zhejiang University

Not yet recruiting

Sitafloxacin-containing Regimens for Shortening Tuberculosis Treatment

Tuberculosis, Pulmonary
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Tuberculous Meningitis

South Africa, Zimbabwe, India, Kenya, Malawi, Mexico, Peru, Brazil, Philippines, Tanzania, Thailand, Vietnam
Hip Innovation Technology

Recruiting

Safety and Effectiveness of the HIT Reverse HRS

Osteoarthritis, Hip | Avascular Necrosis of Hip | Degenerative Joint Disease | Traumatic Arthropathy-Hip

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic... and other conditions

United States
Mural Oncology, Inc
Merck Sharp & Dohme LLC

Recruiting

Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithelial Ovarian Cancer (ARTISTRY-7) (ARTISTRY-7)

Fallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Primary Peritoneal Cancer

United States, Spain, Korea, Republic of, Taiwan, Canada, Israel, France, United Kingdom, Germany, Belgium, Czechia, Singapore, Australia, Austria, Italy
National Cancer Institute (NCI)

Recruiting

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Anal Canal Cloacogenic Carcinoma | Metastatic Anal Squamous Cell Carcinoma | Recurrent Anal Squamous Cell Carcinoma | Stage III Anal Cancer AJCC v8 | Stage IV Anal Cancer AJCC v8 | Unresectable Anal Squamous Cell Carcinoma | Anal Basaloid Squamous Cell Carcinoma

United States
National Taiwan University Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Efficacies of HDDT With or Without Bismuth vs Amoxicillin-metronidazole BQT for First-line H Pylori Eradication

Helicobacter Pylori Infection

Taiwan
Centre Hospitalier Universitaire, Amiens

Recruiting

CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections (CLAZI)

Mycobacterium Avium Complex | Lung Infection

France
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Head and Neck Squamous Cell Carcinoma | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma and other conditions

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection

Puerto Rico, United States, Argentina, Brazil, South Africa, Uganda, Zambia, Haiti, Kenya, Malawi, Tanzania, Thailand, Zimbabwe
Merck Sharp & Dohme LLC

Active, not recruiting

Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)

Neoplasms

Poland, United States, Australia, Canada, China, France, Greece, Israel, Japan, Korea, Republic of, South Africa, Spain
University Hospital, Linkoeping
Linkoeping University

Suspended

Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and Pyrazinamide (HIGHSHORT-RP)

Tuberculosis, Pulmonary

Sweden
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

CBM588, Nivolumab, and Ipilimumab in Treating Patients With Stage IV or Advanced Kidney Cancer

Clear Cell Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Advanced Renal Cell Carcinoma | Unresectable Renal Cell Carcinoma

United States
Purdue University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Effects of Food Form on Cephalic Phase Responses

Overweight | Obese

United States
University of Giessen
Indonesian Directorate General of Higher Education

Completed

Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in Indonesia (FSS)

Body Weight Changes | Motor Activity | Pulmonary Tuberculosis
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Efavirenz (EFV) in HIV-Infected and HIV/Tuberculosis (TB) Coinfected Children

HIV Infections | Tuberculosis

South Africa, Zimbabwe, India, Uganda
National Institute of Allergy and Infectious Diseases...

Completed

Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients

HIV Infections

United States, South Africa
Shaare Zedek Medical Center

Completed

Manipulating the Microbiome in IBD by Antibiotics and FMT (FMT)

Exacerbation of Ulcerative Colitis | Ulcerative Colitis, Active Severe | Crohn's Colitis

Israel, Italy, Canada, Finland, Poland, Spain
AbbVie

Completed

A Study to Evaluate Treatment of Hepatitis C Virus Infection in Pediatric Subjects (ZIRCON)

Chronic Hepatitis C Infection

United States, Belgium, Germany, Puerto Rico, Spain
Thomas Hope

Completed

Gallium-68 PSMA-11 PET Imaging in Prostate Cancer Patients

Prostate Cancer

United States
University of Colorado, Denver

Completed

Effects of Ledipasvir/Sofosbuvir on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF)

Hepatitis C | HIV Coinfection

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Image-Guided Stereotactic Biopsy of High Grade Gliomas

Glioma | Brain Cancer

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Low Energy Shockwave Therapy for Improving Erectile Dysfunction (Shock-ED)

Erectile Dysfunction

France
University of California, San Diego
Merck Sharp & Dohme LLC

Terminated

Raltegravir Cerebrospinal Fluid Pharmacodynamic Study in HIV-Infected Individuals

HIV

United States
Konstantopoulio-Patission General Hospital of Nea...

Unknown

Genotypic Resistance-guided Versus Empirical Therapy for H. Pylori Eradication.

Helicobacter Pylori Infection

Greece
Kaohsiung Veterans General Hospital.

Completed

Comparing the Efficacy of Reverse Hybrid Therapy and Bismuth Quadruple Therapy

Helicobacter Pylori Infection

Taiwan
University of Zimbabwe
State University of New York at Buffalo; Biomedical Research and Training Institute

Completed

Moringa Oleifera- Antiretroviral Pharmacokinetic Drug Interaction

HIV

Zimbabwe
National Taiwan University Hospital

Completed

Efficacy of High-dose Dual Therapy vs Bismuth-containing Quadruple Therapy for First-line Treatment of Hp Infection

Helicobacter Pylori Infection

Taiwan
Kaohsiung Veterans General Hospital.
Kaohsiung Medical University Chung-Ho Memorial Hospital

Completed

Levofloxacin Triple and Bismuth Quadruple Therapies for Rescue Treatment of H Pylori Infection

Helicobacter Pylori Infection

Taiwan
Damascus Hospital

Withdrawn

Comparison Efficacy of 14-day Concomitant Therapy:Clarithromycin vs.Levofloxacin in Eradication of H.Pylori

Helicobacter Pylori Gastrointestinal Tract Infection

Syrian Arab Republic
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Essentiality of INH in TB Therapy

Tuberculosis

South Africa
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

Phase 1, Open Label, Two Arm, Fixed Sequence Study to Evaluate the Effect of Rifampin and Rifabutin on GSK1349572 Pharmacokinetics in Healthy Male and Female Volunteers

Infection, Human Immunodeficiency Virus

United States
Sherief Abd-Elsalam
Tanta University

Unknown

Study of Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori

Helicobacter-associated Gastritis

Egypt
Boehringer Ingelheim

Completed

Nevirapine vs. Atazanavir Boosted With Ritonavir on a Background of Truvada in Human Immunodeficiency Virus (HIV) Infected Naive Patients (NEwArT)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Comprehensive International Program of Research on AIDS

Completed

When to Start Anti-HIV Drugs in Children Infected With HIV (The PREDICT Study)

HIV Infections

Cambodia, Thailand
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Zidovudine/Lamivudine Versus Efavirenz in Combination With Zidovudine/Lamivudine (MERIT)

HIV-1

United States, Canada, United Kingdom, Netherlands, Argentina, Australia, Belgium, South Africa, Switzerland, Italy, Puerto Rico, Brazil, Mexico, Poland
Oslo University Hospital

Unknown

Rifampin Combination Therapy Versus Monotherapy in Early Staphylococcal Infections After Total Hip and Knee Arthroplasty

Staphylococcal Infections | Prosthesis-related Infections

Norway
Abramson Cancer Center of the University of Pennsylvania

Completed

Sorafenib Tosylate and Chemoembolization in Treating Patients With Unresectable Liver Cancer

Hepatocellular Carcinoma | Liver Cancer | Localized Unresectable Liver Cancer

United States
National Cancer Institute (NCI)

Terminated

Erlotinib and Radiation Therapy Plus Combination Chemotherapy in Treating Patients With Inoperable Stage III Non-Small Cell Lung Cancer

Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Adenocarcinoma of the Lung | Bronchoalveolar Cell Lung Cancer | Large Cell Lung Cancer

United States
Duke University
Pfizer; Agency for Healthcare Research and Quality (AHRQ)

Completed

Study of an Intervention to Improve Use of Life-saving Medications for Heart Disease (PILOT-EBM)

Cardiovascular Disease

United States
Yale University
VA Connecticut Healthcare System

Completed

The Effect of Cycloserine on Smoking Behavior in Nicotine Dependent Smokers

Smoking

United States
Centers for Disease Control and Prevention

Completed

TBTC Study 27: Moxifloxacin vs Ethambutol for TB Treatment

Tuberculosis, Pulmonary

Uganda, United States, Canada, South Africa
Abbott

Completed

Effectiveness of ABT-378/Ritonavir Plus Lamivudine Plus Efavirenz Plus Tenofovir DF in HIV-Infected Patients

HIV Infections

United States
National Cancer Institute (NCI)

Not yet recruiting

Anti-Lag-3 (Relatlinib) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent Glioblastoma
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients With Glioblastoma

Glioblastoma | Malignant Glioma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia

Recurrent Severe Aplastic Anemia | Refractory Severe Aplastic Anemia

United States
Thomas Jefferson University
National Cancer Institute (NCI)

Recruiting

An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment

Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Refractory Indolent Adult Non-Hodgkin Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Refractory Marginal Zone Lymphoma | Recurrent Indolent Adult Non-Hodgkin...

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States

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