Search clinical trials for: SOF/VEL

Total 159254 results

Zonguldak Bulent Ecevit University

Completed

Effect of Different Supralottic Airway Devicess on Optic Nerve Sheath Diameter

Intracranial Pressure Increase | Supraglottic Airway Device | Optic Nerve Sheath Diameter

Turkey
Aswan University Hospital

Not yet recruiting

Developmental Endothelial Locus-1, Platelet Count, and Soluble P-selectin in Overweight and Obese Subjects

Overweight and Obesity

Egypt
Veloxis Pharmaceuticals

Completed

A Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VEL-101

Healthy Volunteers

United States
Kirby Institute

Completed

Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in PWID and People With HIV Coinfection. (REACT)

Hepatitis C

Australia, United States, United Kingdom, New Zealand, Switzerland, Canada, Germany, Netherlands
Ahmed A. H. Abdellatif

Unknown

Topical Silver Nanoparticles for Microbial Activity

Infection, Bacterial | Foot Infection Fungal

Saudi Arabia
Gilead Sciences

Terminated

Study to Investigate Pharmacokinetics, Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) Fixed Dose Combination (FDC) in Adolescents and Children With Chronic Hepatitis C Virus (HCV) Infection

Hepatitis C Virus Infection

Poland, Italy, United Kingdom
Gilead Sciences

Completed

Safety and Efficacy of SOF/VEL/VOX FDC for 12 Weeks and SOF/VEL for 12 Weeks in DAA-Experienced Adults With Chronic HCV Infection Who Have Not Received an NS5A Inhibitor (POLARIS-4)

Hepatitis C Virus Infection

United States, France, United Kingdom, Germany, Canada, Australia, New Zealand, Puerto Rico
Gilead Sciences

Completed

Safety and Efficacy of SOF/VEL/VOX FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis (POLARIS-3)

Hepatitis C Virus Infection

United States, France, United Kingdom, Germany, Australia, Canada, New Zealand, Puerto Rico
Gilead Sciences

Completed

Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy (POLARIS-2)

Hepatitis C

United States, France, United Kingdom, Germany, Canada, Australia, New Zealand, Puerto Rico
Johns Hopkins University

Completed

deLIVER: Direct Acting Antiviral Effects on the Liver (deLIVER)

HIV | Liver Disease | HCV Coinfection

United States
Gilead Sciences

Completed

Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir (SOF/VEL) Fixed-Dose Combination (FDC) and Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX ) FDC for 12 Weeks in Adults With Chronic Hepatitis C Virus (HCV) Infection

Hepatitis C Virus Infection

Korea, Republic of
Medical University of Vienna

Unknown

Short-term Endothelin A Receptor Blockade in Patients With On-pump CABG

Coronary Artery Disease | Aorto-coronary Bypass Grafting

Austria
Gilead Sciences

Terminated

A Registry for Participants With Cirrhosis Who Achieve a Sustained Virologic Response Following Treatment With a Sofosbuvir-Based Regimen Without Interferon for Chronic Hepatitis C Infection

Hepatitis C Virus Infection

France, Spain, United States, Australia, Canada, Germany, United Kingdom, Italy, New Zealand, Puerto Rico
Hôpital Universitaire Sahloul

Completed

Nigelle 5 in Prevention of Influanza (NigCOV3)

COVID-19 Acute Respiratory Distress Syndrome

Tunisia
Gilead Sciences

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Voxilaprevir in Adults With Chronic Hepatitis C Virus Infection

Hepatitis C Virus Infection

United States, Puerto Rico
Hôpital Universitaire Sahloul

Completed

Nigella 5 in the Treatment of SARS COV2 (COVID-19) (Nigelle5)

SARS-CoV2 Infection

Tunisia
G&E Herbal Biotechnology Co., LTD

Suspended

Efficacy and Safety of SR-T100 Gel in Common Warts (CW) Patients

Common Wart
Glyciome, LLC
Brigham and Women's Hospital; University of Puerto Rico

Completed

Perception & Acceptability of a Cervical Cancer Prevention Prebiotic Device

Sensory Perceptual Characteristics | User Acceptability of Gel Delivery System

United States, Puerto Rico
Novan, Inc.

Completed

A Phase 2, 3 Arm Study of NVN1000 Gel and Vehicle Gel in Subjects With Acne

Acne Vulgaris

Dominican Republic, Honduras, Panama
Starpharma Pty Ltd

Completed

Dose Ranging Study of SPL7013 Gel for Treatment of Bacterial Vaginosis (BV)

Bacterial Vaginosis

United States
MediWound Ltd

Completed

A Study to Evaluate the Efficacy and Safety of NexoBrid in Subjects With Thermal Burns

Thermal Burns

United States, Israel, Belgium, Czechia, Georgia, Germany, Italy, Romania
Integra LifeSciences Corporation
Integrium

Terminated

Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers (STRIDE 2)

Diabetic Foot Ulcers

United States, Puerto Rico, Canada, South Africa
Starpharma Pty Ltd

Completed

Dose-ranging Study of SPL7013 Gel for the Prevention of Bacterial Vaginosis (BV)

Recurrent Bacterial Vaginosis (BV)
DermBiont, Inc.

Active, not recruiting

A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Tinea Pedis

Tinea Pedis

United States
NFlection Therapeutics, Inc.

Completed

NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

Neurofibromatosis 1 | Cutaneous Neurofibroma

United States
Alcon Research

Completed

In Vivo Measurement of Corneal Epithelial Changes in Dry Eye Patients

Dry Eye Syndrome
University of Nebraska

Completed

Impact of Oral Hygiene Gels on Peri-implant Mucositis

Mucositis

United States
Kessler Foundation

Unknown

Pairing Functional Electrical Stimulation (FES) and Volitional Effort Training Promotes Neuroplasticity and Motor Gain

Stroke | Drop Foot
Topokine Therapeutics, Inc.

Suspended

Safety and Feasibility Study of XAF5 Gel for Reduction of Submental Fat

Excess Submental Fat ("Double Chin")
Kamedis Ltd.

Unknown

Clinical Study to Evaluate Safety and Efficacy of KAM1403 Gel to Treat Radiation Dermatitis (kam1403)

Radiation Dermatitis

Israel
B. Braun Ltd. Centre of Excellence Infection Control

Terminated

HM242-Gel vs Comparator

Venous Leg Ulcer

Czechia, Slovakia
Bausch Health Americas, Inc.

Completed

Absorption and Systematic Pharmacokinetics of Topically Applied IDP-120 Gel

Acne

United States
Population Council

Completed

Study to Evaluate the Safety of Griffithsin in a Carrageenan Gel in Healthy Women

HIV Infection

United States
Nutravalia
Slb Pharma

Completed

Effect of ANACA3 Slimming Gel on Loss of Abdominal and Thigh Circumferences in Healthy Volunteers

Overweight and Obesity

France
Selecta Biosciences, Inc.

Completed

Safety and Pharmacodynamics of SEL-212 (Pegsiticase + SEL-110) in Subjects With Elevated Blood Uric Acid Levels

Gout

United States
Xinnate AB
Region Skane

Completed

Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.

Blister | Epidermolysis Bullosa | Wound of Skin | Varicose Ulcer of Lower Limb

Sweden
Suzhou Kintor Pharmaceutical Inc,

Completed

Study in Subjects to Evaluate the Safety, Tolerability and Pharmacokinetics of GT20029

Acne Vulgaris | Androgenetic Alopecia

United States
Galderma R&D

Completed

Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea

Rosacea

United States
G&E Herbal Biotechnology Co., LTD

Completed

Efficacy Study & Safety Evaluation of SR-T100 Gel in Actinic Keratosis Treatment

Actinic Keratosis

Taiwan
Peplin

Completed

A Multicenter Study to Evaluate the Safety and Efficacy of PEP005 Topical Gel When Used to Treat Actinic Keratoses on the Head (Face or Scalp)

Actinic Keratosis

United States, Australia
Korea University
Samsung Medical Center; Asan Medical Center; Chonnam National University Hospital and other collaborators

Completed

Clinical Trial of Ingenol Mebutate Gel 0.015% & 0.05% in Actinic Keratosis

Actinic Keratosis

Korea, Republic of
Bausch Health Americas, Inc.

Completed

Open-Label, Randomized Study Evaluating the Absorption and Systemic Pharmacokinetics of Topically Applied IDP-126 Gel in Comparison With Control Gel

Acne Vulgaris

United States
LEO Pharma

Completed

Efficacy and Safety of LEO 43204 in the Field Treatment of Actinic Keratosis on Face or Chest including12-month Follow-up

Actinic Keratosis

United States
NFlection Therapeutics, Inc.

Completed

NFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

Neurofibromatosis 1 | Cutaneous Neurofibroma

United States
LEO Pharma

Completed

Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up

Actinic Keratosis

United States
Chang Gung Memorial Hospital

Unknown

Silicone Gel to Improve Scar in Microtia Patients

Scar | Microtia

Taiwan
Kalypsys, Inc.

Completed

A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)

Neuropathic Pain | Herpes Zoster | Postherpetic Neuralgia | Shingles

United States
GlaxoSmithKline

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetic of Single and 14 Day Repeat Topical Application of GSK1940029

Acne Vulgaris

Australia
Novan, Inc.

Completed

Cutaneous Tolerability and Safety of NVN1000 Topical Gel in Healthy Volunteers

Acne Vulgaris

United States
Karyopharm Therapeutics Inc

Withdrawn

Study of Safety, Tolerability, and Pharmacokinetics of Topical Selinexor (KPT-330) Diabetic Foot Ulcer (DFU) Patients

Diabetic Foot Ulcers

New Zealand

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