Search clinical trials for: SPR720

Total 28 results

Spero Therapeutics

Recruiting

A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)

United States
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States
Spero Therapeutics
Simbec Research

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Spero Therapeutics

Terminated

Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Mycobacterium Avium Complex | Non-tuberculous Mycobacterium Pulmonary Disease

United States
Serenity Pharmaceuticals, Inc.

Completed

Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia

Nocturia

United States
Serenity Pharmaceuticals, Inc.

Completed

Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia - DB4 (DB4)

Nocturia

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Clinical Study Evaluating the Relative Bioavailability of SHR7280 Dry Suspension and Tablets

Endometriosis, Uterine Fibroids, Male Hormone-sensitive Prostate Cancer, Assisted Reproduction

China
Spero Therapeutics
United States Department of Defense

Completed

Phase 1 Study of PK and Safety of SPR206 in Subjects With Various Degrees Of Renal Function

Renal Impairment

New Zealand
Serenity Pharmaceuticals, Inc.

Completed

Treatment of Patients With Nocturia (Non-PK Study)

Nocturia

United States
Serenity Pharmaceuticals, Inc.

Completed

Study to Investigate the Safety and Pharmacokinetics of SER120 Nasal Spray in Elderly Patients With Nocturia

Nocturia

United States
Spero Therapeutics

Completed

A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants

Healthy Volunteers

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Identify Effective Doses of SHR7280 Tablets in Controlled Ovarian Hyperstimulation (COH) for Female Subjects Undergoing Assisted Reproductive Technology (ART)

Female Subjects Undergoing COH in ART to Prevent Early Ovulation

China
Serenity Pharmaceuticals, Inc.

Completed

Treatment of Patients With Nocturia

Nocturia

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

The PK/PD Study of SHR7280 Tablets in Healthy Subjects.

Healthy Subjects

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Phase 1 Dose Escalation and Expansion Study Of SHR7280 In Subjects With Hormone Sensitive Prostate Cancer

Hormone Sensitive Prostate Cancer

China
Spero Therapeutics
United States Department of Defense

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR206 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

The Pharmacokinetic(PK)/Pharmacodynamics(PD) Study of SHR7280 Tablets in Premenopausal Subjects With Endometriosis.

Endometriosis

China
Shanghai SIMR Biotechnology Co., Ltd.

Completed

The Pharmacokinetics (PK), Safety, Tolerability of SR750 in Healthy Volunteers

Healthy

China
Navitor Pharmaceuticals, Inc.
Supernus Pharmaceuticals, Inc.

Recruiting

Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression

Treatment Resistant Depression

United States
Spero Therapeutics
Clinical Network Services (CNS) Pty Ltd

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR206 in Healthy Volunteers

Healthy Volunteers

Australia
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Phase II/III Study of Efficacy and Safety of SHR7280 Tablets in Subjects With Menorrhagia With Uterine Fibroids

Uterine Fibroids With Menorrhagia

China
SIMR (Australia) Biotech Pty Ltd.

Completed

The Safety, Tolerability, and Pharmacokinetics (PK) of SR750 in Healthy Volunteers

Healthy Volunteers

Australia
Serenity Pharmaceuticals, Inc.

Completed

Long Term Safety Assessment of SER120 in Patients With Nocturia

Nocturia

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

To Compare the Efficacy and Safety of Oral SHR 7280 Tablets With Ganirelix Acetate Injection in Infertile Female Subjects

Infertile Female Subjects Undergoing Controlled Ovarian Hyperstimulation to Suppress Premature LH Surge and Prevent Early Ovulation

China
Spero Therapeutics
CPR Pharma Services Pty Ltd, Australia

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of SPR741 in Healthy Volunteers

Healthy Volunteers

Australia
Spero Therapeutics
Simbec Research; QPS Holdings LLC

Completed

Phase 1 Study to Evaluate DDI, PK, Safety, Tolerability of SPR741

Healthy Volunteers

United Kingdom
Futura Medical Developments Ltd.
Parexel

Completed

Assess the Efficacy and Safety in Volunteers of DCF100, TIB200 and SPR300 vs. Placebo and Control(s) in a UV Pain Model

Pain

United Kingdom
Insel Gruppe AG, University Hospital Bern

Completed

Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery (SPRV)

Drug Interactions | Anesthesia, Conduction

Switzerland

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