Search clinical trials for: SPR720 1000 mg

Total 11702 results

Spero Therapeutics

Recruiting

A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)

United States
Serenity Pharmaceuticals, Inc.

Completed

Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia

Nocturia

United States
Abbott
PPD

Completed

Study to Investigate the Effects of Different Doses of S-adenosyl-L-methionine (SAMe) in Subjects With Nonalcoholic Fatty Liver Disease and Non-treated Matched Healthy Volunteers as Control Group (EXPO)

Non Alcoholic Fatty Liver Disease

France, Germany, Poland, Russian Federation
Spectrum Pharmaceuticals, Inc

Completed

Study to Assess the Safety and the Phosphate Binding Capacity of Renazorb (SPI-014)

Safety | Phosphate Binding Capacity

United States
GlaxoSmithKline

Completed

A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin

Diabetes Mellitus, Type 2

United States, Taiwan, Argentina, Canada, Philippines, Korea, Republic of, Mexico, Brazil, Pakistan
HighTide Biopharma Pty Ltd

Completed

A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia

Hypercholesterolemia

Australia
Wockhardt
Quintiles, Inc.

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of WCK 5107 Alone and in Combination With Cefepime

Healthy

United States
Serenity Pharmaceuticals, Inc.

Completed

Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia - DB4 (DB4)

Nocturia

United States
GlaxoSmithKline

Terminated

A Study to Evaluate Single and Repeat Doses of IV GSK2251052 in Healthy Male Japanese and Caucasian Subjects and Repeat Doses of Supratherapeutic Doses of IV GSK2251052 in Healthy Volunteers

Community-acquired Infection

United States
MedImmune LLC

Completed

Phase 1 Single-ascending Dose Study to Evaluate Safety and Tolerability of MEDI4920 in Healthy Adults

Healthy Volunteer

United Kingdom
Inmunotek S.L.

Completed

Dose Finding for the Treatment of Rhinitis/Rhinoconjunctivitis Against Grass Pollen Allergy (MG56)

Rhinitis | Rhinoconjunctivitis

Spain
Joben Bio-Medical Co., Ltd.
Kaohsiung Medical University Chung-Ho Memorial Hospital; Taipei Veterans General... and other collaborators

Unknown

Orally Administrated JBM-TC4 Prevents Acute Radiodermatitis in Breast Cancer Patients

Radiodermatitis

Taiwan
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States
Oslo University Hospital

Recruiting

A Pilot Study for Optimizing Meropenem Administration in the ICU (MER6)

Drug Effect

Norway
Rabin Medical Center

Unknown

Effect of Fish Oil on Surgery Pain After Knee Replacement Patients: Randomized, Prospective, Double Blind, Placebo Control Trial (EFOPaKR-01)

Rheumatoid Arthritis

Israel
GlaxoSmithKline

Completed

A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C -GSK1322322 After an Intravenous and an Oral Dose

Infections, Bacterial

United States
Gmax Biopharm LLC.

Recruiting

A Study of GMA301 in Subjects With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, China
Spero Therapeutics
Simbec Research

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Mayo Clinic

Recruiting

A Study of Perturbation of Human Small Intestinal Colonic Permeability

Healthy

United States
Global Alliance for TB Drug Development

Completed

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-003)

Tuberculosis

United States
gicare Pharma Inc.
Algorithme Pharma Inc

Completed

Study on Analgesia of GIC-1001 & GIC-1002 on Visceral Pain, Rectal Sensory Threshold Using the Barostat Method

Pain | Cancer | Colonic Disease

Canada
Mid Atlantic Retina

Completed

Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachments

Diabetic Retinopathy | Retinal Detachment | Vitrectomy | Proliferative Vitreoretinopathy

United States
Natureceuticals Sdn Bhd

Completed

Evaluation of Clinical Efficacy and Safety of Nuvastatic in Cancer Asthenia

Cancer | Asthenia

India
GlaxoSmithKline

Completed

Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Advanced Or Metastatic Breast Cancer

Neoplasms, Breast

United Kingdom, United States, Peru, Israel, Poland, Russian Federation, Korea, Republic of, Thailand, Pakistan, Hungary, India, Canada, France, Mexico, Malaysia, Singapore
Pharmacosmos A/S

Completed

Open-label Pharmacokinetic Study of Iron Isomaltoside 1000 (Monofer®) Administered by 500 mg IV Bolus Injection or 1000 mg Intravenous Infusion to Patients With Non-hematological Malignancies Associated With Chemotherapy Induced Anaemia (CIA) (PK-CIA-04)

Non-hematological Malignancies
Angiogenix

Unknown

PK and PD Responses to Oral L-Citrulline in Patients With Sickle Cell Disease

Sickle Cell Disease

United States
GlaxoSmithKline

Completed

Single Dose Escalation First Time in Human PK Study

Infections, Bacterial

Australia
Chang Gung Memorial Hospital

Active, not recruiting

Treatment for Major Depressive Disorder With Intermittent Theta-burst Stimulation (iTBS)

Depressive Disorder, Treatment-Resistant

Taiwan
Salzburger Landeskliniken

Enrolling by invitation

Propionic Acid in Multiple Sclerosis (MADAI)

Multiple Sclerosis

Austria
Innate Pharma

Completed

Safety and Tolerability of NNC0141-0000-0100 in Subjects With Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Germany
LG Chem

Unknown

Bioequivalence Study for Gemigliptin/Metformin 50/1000 mg and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.

Type2 Diabetes
Oslo University Hospital

Recruiting

Immunosafe-CeD: Are Partially Hydrolysed Gluten Hamrful to Celiac Disease Patients?

Celiac Disease | Food Intolerance

Norway, Germany
ModernaTX, Inc.

Completed

A Study of mRNA-1020 and mRNA-1030 Seasonal Influenza Vaccines in Healthy Adults

Seasonal Influenza

United States
AstraZeneca
Parexel

Completed

A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-administration.

Type 2 Diabetes Mellitus

United States
LG Chem

Completed

Bioequivalence Study for Fixed Dose Combination Zemimet® SR Tab. 50/1000 and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.

Type 2 Diabetes

Thailand
Ministry of Health, Turkey
Istanbul University; Ankara Training and Research Hospital; Prof. Dr. Cemil Tascıoglu... and other collaborators

Active, not recruiting

Efficacy and Safety of Hydroxychloroquine and Favipiravir in the Treatment of Mild to Moderate COVID-19

COVID-19 | Sars-CoV2

Turkey
Sandoz

Completed

A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions

Type 2 Diabetes
SFJ Pharmaceuticals, Inc.
SFJ Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Safety, Tolerability, PK, and PD of PB2452 With and Without Ticagrelor Pretreatment in Chinese Healthy Volunteers

Healthy

China
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ)

Malaria

United Kingdom
Spanish Oncology Genito-Urinary Group
Roche Pharma AG

Completed

Study of Atezolizumab Combined With Split-dose Gemcitabine Plus Cisplatin in Urothelial Carcinoma (AUREA)

Locally Advanced or Metastatic Urothelial Carcinoma

Spain
Bumi Herman

Completed

Vitamin D Supplementation and Clinical Improvement in COVID-19

COVID-19

Indonesia
Staidson (Beijing) Biopharmaceuticals Co., Ltd

Terminated

A Study of STSA-1002 Combined With STSA-1005 in Healthy Subjects

Healthy Subject

China
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Valacyclovir Hydrochloride Tablets 1000 mg and Valtrex® Tablets 1000 mg

Healthy

United States
Disphar International B.V.

Withdrawn

Comparative Bioavailability Study of Metformin HCl 1000 mg Granules vs Glucophage 1000 mg Film-coated Tablet

Comparative Bioavailability

Jordan
Mylan Pharmaceuticals Inc

Completed

Food Study of Valacyclovir Hydrochloride Tablets 1000 mg to Valtrex® Tablets 1000 mg

Healthy

United States
Quark Pharmaceuticals

Terminated

Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)

Non Arteritic Anterior Ischemic Optic Neuropathy

United States, Australia, Germany, China, India, Italy, Singapore, Israel
Maastricht University Medical Center

Completed

Bio-equivalence Study

Bioavailability | Bioequivalence

Netherlands
Centre Hospitalier Universitaire, Amiens
Merck Serono International SA

Completed

May Metformin be Used in Renal Failure?

Renal Disorder Associated With Type II Diabetes Mellitus

France
Ixchelsis Limited

Completed

Relative Bioavailability Study of IX-01 Caplet Versus Aqueous Dispersion and Food Effect of the Caplet in Healthy Males (IX-0106 RBA)

Healthy

United States

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