Search clinical trials for: SRP-4053

Total 1575 results

Sarepta Therapeutics, Inc.
University College, London; Catholic University of the Sacred Heart; University... and other collaborators

Completed

Phase I/II Study of SRP-4053 in DMD Patients

Duchenne Muscular Dystrophy

United Kingdom, United States, France, Italy
Kevin Flanigan
Sarepta Therapeutics, Inc.

Completed

A 48-Week, Open Label, Study to Evaluate the Efficacy and Safety of AMONDYS 45, EXONDYS 51, VYONDYS 53 in Subjects With DuchenneMuscular Dystrophy Carrying Eligible DMD Duplications.

Duchenne Muscular Dystrophy

United States
Sarepta Therapeutics, Inc.

Terminated

An Extension Study to Evaluate Casimersen or Golodirsen in Patients With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

United States, Belgium, Canada, Spain, United Kingdom, Czechia, Germany, Israel, Bulgaria, France, Italy, Poland, Sweden
Sarepta Therapeutics, Inc.

Active, not recruiting

Study of SRP-4045 (Casimersen) and SRP-4053 (Golodirsen) in Participants With Duchenne Muscular Dystrophy (DMD) (ESSENCE)

Duchenne Muscular Dystrophy

United States, Korea, Republic of, Italy, United Kingdom, Canada, Poland, Spain, France, Germany, Belgium, Australia, Czechia, Serbia, Greece, Argentina, Bulgaria, Denmark, Hungary, India, Ireland, Israel, Mexico, Russian Federation, ...
Eisai Co., Ltd.

Completed

A Pharmacokinetic (PK) Study of Three Types of E0302 Sustained Release (SR) Tablets Compared With E0302 Immediate Release (IR) Tablet Under Fed Conditions in Healthy Participants

Healthy Subjects

New Zealand
Neurovance, Inc.

Completed

A Study to Evaluate the Safety, Tolerance, and Pharmacokinetic and Pharmacodynamic Profile Of 1 SR Formulation of EB-1020

Normal, Healthy Volunteers

Australia
Ono Pharmaceutical Co. Ltd

Completed

A Human Mass Balance Study to Determine the Total Recovery of Radioactivity in Urine and Faeces Following a Single Oral Dose of 14C Radiolabelled ONO-4053

Healthy Adult Male Subjects

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers

Healthy Adult Subjects

United Kingdom
Ono Pharmaceutical Co. Ltd

Terminated

A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers

Healthy Adult Subjects

United Kingdom
University of Arkansas

Terminated

Preoperative SRS/SRT vs Postoperative SRS/SRT for Brain Metastases

Brain Metastases

United States
Polish Mother Memorial Hospital Research Institute

Completed

The Impact of Positioning on Bottle-feeding in Preterm Infants. A Comparative Study PMMHHRI-2018/V/9-SZB

Bottle Feeding | Premature

Poland
University of Belgrade

Completed

Effect of Injectable Platelet-Rich Fibrin (i-PRF) in Initial Treatment of Chronic Periodontitis (EIPRFITCP)

Periodontitis

Serbia
University of Pisa

Completed

Acute-phase Response & Periodontal Treatment in Diabetes Affected Patients (PERIO-DIA)

Diabetes | Periodontitis

Italy
Liminal BioSciences Ltd.

Terminated

Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome

Alström Syndrome

United Kingdom
Liminal BioSciences Ltd.

Completed

Safety and Tolerability of PBI-4050 and Its Effects on the Biomarkers in Subjects With Alström Syndrome

Diabetes | Inflammation and Fibrosis

United Kingdom
University of Pavia

Completed

A New Protocol for the Management of Dental Erosion in Rugby Players

Dental Erosion

Italy
Maxwell Biomedical

Recruiting

Initial Experience With Spatial Resynchronization Therapy in Patients With Atrial Fibrillation (SR-TheAF)

Atrial Fibrillation

Georgia
University of Ljubljana
University Medical Centre Ljubljana

Recruiting

Low Laser Therapy and Hyaluronic Acid as an Adjunct to Non-surgical Periodontal Therapy

Periodontitis

Slovenia
G. d'Annunzio University

Not yet recruiting

Efficacy of rhPDGF as an Adjunct to Non-surgical Periodontal Therapy of Intrabony Defects

Periodontal Diseases | Intrabony Periodontal Defect | Periodontal Attachment Loss | Pocket, Periodontal
Liminal BioSciences Ltd.

Completed

A Healthy Volunteer Study of PBI-4050

Fibrosis | Inflammation

United Kingdom
Clavis Pharma

Completed

Clinical Study of Previously Untreated Patients With Malignant Melanoma

Neoplasm Metastasis | Malignant Melanoma

United States, Norway, Sweden
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Phase I Study of HRS-7053 Injection in the Treatment of Patients With Advanced Malignancies

Advanced Malignant Cancer
Sunovion

Terminated

A Multiple Ascending Oral Dose Evaluation of the Safety, Tolerability, and Pharmacokinetics of DSP-1053 and Its Metabolites in Healthy Subjects and in Subjects With Major Depressive Disorder (MAD)

Healthy

United States
Liminal BioSciences Ltd.

Terminated

Study to Evaluate Safety, Efficacy of PBI-4050 & Its Effect on Relevant Biomarkers in T2DM Patients With Metabolic Syndrome

Type 2 Diabetes Mellitus | Metabolic Syndrome

Canada
South Rampart Pharma, LLC

Active, not recruiting

Safety and Pharmacokinetics of SAD/MAD Oral Doses of SRP-3D (DA)

Pain

United States
Novo Nordisk A/S

Terminated

A Two Part Trial Investigating an Anti-obesity Drug in Overweight/Obese Male and Female Healthy Volunteers

Obesity | Metabolism and Nutrition Disorder

United States
Belén Retamal-Valdes

Active, not recruiting

Amoxicillin and Metronidazole During or After the Periodontal Treatment

Periodontitis

Brazil
Gilead Sciences

Completed

Study to Assess the Long-term Safety and Efficacy of Tirabrutinib in Adults With Relapsed/Refractory B-cell Malignancies

Relapsed/Refractory B-cell Malignancies

France, United Kingdom
Gilead Sciences
Ono Pharmaceutical Co. Ltd

Completed

Study to Evaluate the Safety and Tolerability of Tirabrutinib (ONO/GS-4059) Given as Monotherapy in Participants With Relapsed/Refractory NHL and CLL

Chronic Lymphocytic Leukaemia | Non Hodgkins Lymphoma

United Kingdom, France
Pfizer

Completed

Study to Estimate the Relative Bioavailability Compared to Commercial Extended-release Tablet Formulation and the Effects of Food Or Sprinkling on Applesauce for Fesoterodine Sustained-release Beads-in-capsule Formulations in Healthy Adult Volunteers

Healthy

Belgium
Gilead Sciences
Ono Pharmaceutical Co. Ltd

Completed

Study to Evaluate Safety and Pharmacokinetics of GS-4059 (Tirabrutinib) in Healthy Volunteers and Participants With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States
Clavis Pharma

Completed

A Phase II Study of CP-4055 as Second Line Therapy in Patients With Advanced Colorectal Cancer

Colorectal Cancer | Advanced Colorectal Cancer

United Kingdom
Yuzuncu Yıl University

Completed

Effects of Er,Cr:YSGG, Diode Lasers on GCF Cytokines Levels

Aggressive Periodontitis
Postgraduate Institute of Dental Sciences Rohtak

Completed

SRP, Systemic Inflammation and Serum Bone Resorption Markers Premenopausal Women With Periodontitis and Low BMD

Periodontitis

India
Postgraduate Institute of Dental Sciences Rohtak

Unknown

Influence of Mouth Breathing on Periodontal Healing

Chronic Periodontitis

India
Government Dental College and Research Institute...

Completed

Clinical Efficacy of 0.75% Boric Acid Gel in Chronic Periodontitis

Chronic Periodontitis

India
Hero Institute for Infant Nutrition
Universidad de Murcia; University of Valencia; Universidad de Granada

Completed

Effects of Probiotics in Immune System of Healthy Adults (SETOPROB)

Conditions Influencing Health Status

Spain
Cairo University

Not yet recruiting

BMP-2 and ALP Levels Following Laser Therapy With Scaling and Root Planing in Periodontitis- RCT.

Periodontitis, Laser
Clavis Pharma
Syneos Health; Theradex; CardiaBase; Learn & Confirm

Completed

The Pharmacokinetics and Cardiac Properties of Elacytarabine (CP-4055)

Relapsed/Refractory AML

United Kingdom, Spain
Shanghai Haiyan Pharmaceutical Technology Co.,...

Recruiting

A Phase 1 Study of YZJ-5053 Tablets in Participants With Advanced Solid Tumors

Solid Tumor

China
Postgraduate Institute of Dental Sciences Rohtak

Completed

Emblica Officinalis Irrigation in Periodontitis

Periodontitis

India
Odontostomatologic Laser Therapy Center, Florence...

Completed

Diode Laser and SRP in Chronic Periodontitis (PAPD)

Periodontitis

Italy
Dr. D. Y. Patil Dental College & Hospital

Completed

Locally Delivered Aloe Vera Gel in the Treatment of Chronic Periodontitis Patients With Diabetes Mellitus

Diabetes Mellitus | Chronic Periodontitis
Hutchison Medipharma Limited

Recruiting

HMPL-453 in Advanced Malignant Mesothelioma

Advanced Malignant Mesothelioma

China
Hutchison Medipharma Limited

Unknown

A Study of HMPL-453 in Patients With Advanced Solid Malignancies

Solid Tumor, Adult

China
Hutchison Medipharma Limited

Terminated

A Dose Escalation Study to Assess the Safety and Tolerability of HMPL-453 in Patients With Advanced Solid Malignancies

Solid Tumor

Australia
Government Dental College and Research Institute...

Completed

Comparison of Rosuvastatin With Atorvastatin in Chronic Periodontitis

Chronic Periodontitis
Yuzuncu Yıl University

Completed

Does Hyaluronic Acid Affect Periodontal Treatment?

Periodontitis

Turkey
Sarepta Therapeutics, Inc.

Terminated

An Open-Label Extension Study for Patients With Duchenne Muscular Dystrophy Who Participated in Studies of SRP-5051 (Vesleteplirsen)

Muscular Dystrophy, Duchenne

United States, Canada
University of Alabama at Birmingham

Recruiting

Novel Dental Gel as an Adjunct to Scaling and Root Planing

Periodontal Diseases | Gingival Diseases | Plaque, Dental | Gingival Pocket | Gum Bleed

United States

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