Search clinical trials for: Safinamide, MAO-B inhibitor

Total 2294 results

University of North Carolina, Chapel Hill
Celgene Corporation

Terminated

Open Label of Thalidomide in Treatment of Women With Chronic Pelvic Pain Associated With Endometriosis

Endometriosis

United States
University of Erlangen-Nürnberg Medical School

Recruiting

Radiotherapy With Pembrolizumab in Metastatic HNSCC

Head and Neck Squamous Cell Carcinoma

Germany
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (150 mg/850 mg) With Respect to the Individual Components of Canagliflozin (1 x 300 mg) and Metformin IR Tablets (2 x 850 mg) in Healthy Volunteers

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

Healthy

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (50 mg/1,000 mg) With Respect to the Individual Components of Canagliflozin (1 x 100 mg) and Metformin IR Tablets (2 x 1,000 mg) in Healthy Volunteers

Healthy

United States
Shaare Zedek Medical Center

Unknown

Methylphenidate in Healthy Young Adults

Healthy
University of Cincinnati
National Institute of Mental Health (NIMH)

Completed

Neuroimaging Study of Risk Factors for Adolescent Bipolar Disorder (NERF)

Attention Deficit Hyperactivity Disorder

United States
University Hospital Inselspital, Berne

Completed

Adjunctive Sedation With Dexmedetomidine for the Prevention of Severe Inflammation and Septic Encephalopathy (ADVISE)

Sepsis-Associated Encephalopathy

Switzerland
Sun Yat-sen University

Active, not recruiting

Cetuximab Plus FOLFOXIRI vs Cetuximab Plus FOLFOX For CRCLM

Colorectal Cancer | Liver Metastases

China
Yonsei University

Completed

The Effect of Antihypertensive Agents Concerning With Hemodynamics and Reduction of Anaesthetics in Orthognathic Surgery

Orthognathic Surgery

Korea, Republic of
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Nodal Marginal Zone Lymphoma

United States
National Taiwan University Hospital

Recruiting

Spleen Irradiation With Nanoliposomal Irinotecan Plus 5-FU and Leucovorin in Metastatic Pancreatic Adenocarcinoma (SINAI)

Metastatic Pancreatic Cancer

Taiwan
Criterium, Inc.
Amgen

Active, not recruiting

FOLFOXIRI Plus Panitumumab in Metastatic RAS Wild-type, Left-sided Colorectal Cancer

Colorectal Cancer Metastatic

United States
Anhui Medical University
Peking University First Hospital; China Medical University Hospital; Huashan... and other collaborators

Completed

Effect of Enalapril Plus Folic Acid on Blood Pressure and Glycometabolism

Blood Pressure | Plasma Total Homocysteine Level

China
Erasmus Medical Center

Completed

The Effects of the Proton Pump Inhibitor Esomeprazole on the Bioavailability of Regorafenib (REGORA)

Colorectal Neoplasms | Gastrointestinal Stromal Tumors

Netherlands
Shalvata Mental Health Center
Technion, Israel Institute of Technology

Unknown

A Double Blind Crossover Study on the Effect of Methylphenidate on Decision-making Ability of Adults With ADHD Compared to Healthy Adults

ADHD

Israel
National Cancer Center, Korea

Active, not recruiting

Efficacy and Safety of Atezolizumab Plus Capecitabine Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

Triple Negative Breast Cancer

Korea, Republic of
IlDong Pharmaceutical Co Ltd

Completed

Bioequivalence Study to Compare the Pharmacokinetics of Besifovir in Healthy Adult Volunteers

Chronic Hepatitis B
Hospital Clinic of Barcelona

Completed

Atazanavir or Lopinavir in HIV Post-exposure Prophylaxis

HIV Infections

Spain
Mylan Inc.
Mylan Bertek Pharmaceuticals

Terminated

Effects of Therapy With Sulfamylon® 5% Topical Solution Compared to a Historical Control Group

Burns

United States
Per Pfeiffer

Completed

Chemotherapy for Patients With Locally Advanced Pancreatic Cancer (LAPC) With Additional Chemo-radiotherapy (CRT) for Patients With Borderline Resectable Tumours

Pancreatic Cancer

Denmark
Janssen Research & Development, LLC

Completed

A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants

Healthy

United States
Yonsei University

Completed

A Study of Neoadjuvant Chemoradiotherapy With 5-FU/Leucovorin (FL) vs. TS-1/Irinotecan in Patients With Locally Advanced Rectal Cancer

Rectal Cancer

Korea, Republic of
Sandoz

Completed

A Phase I/II Pilot Study of Simultaneously Administered Rhu GM-CSF ( CHO Cell ) and Azidothymidine ( AZT ) in Patients With Severe HIV Infection and Leukopenia: Pharmacokinetics and Feasibility

HIV Infections | Cytopenias

United States
Gilead Sciences

Completed

Safety and Efficacy of Switching From Dolutegravir and ABC/3TC or ABC/DTG/3TC to B/F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed

HIV-1 Infection

Spain, United States, France, Italy, Germany, Canada, United Kingdom, Belgium, Puerto Rico, Australia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Evaluating Pharmacokinetic Interactions With Vaginal Ring Contraceptives and ART

HIV-1 Infection

United States, Peru, Puerto Rico, Brazil, Botswana, Kenya, South Africa, Thailand
Inna Chen, MD

Recruiting

Nivolumab With Ipilimumab Combined With TGFβ-15 Peptide Vaccine and Radiotherapy for Pancreatic Cancer (CheckVAC)

Pancreatic Cancer

Denmark
University of Southern California
The University of Texas Health Science Center, Houston; Universidad Peruana...

Recruiting

Linezolid for Syphilis Pilot Study

Syphilis

United States
Radboud University Medical Center
UMC Utrecht

Completed

Pharmacokinetics of Piperacillin and Tazobactam in Critically Ill Patients (PICTAR)

Bacterial Infections

Netherlands
Henrik Frederiksen

Unknown

MethylphenIdate for Fatigue in Haematological Cancer (MICRO)

Hematological Cancer

Denmark
Kimford Jay Meador

Completed

Methylphenidate Treatment of Attention Deficits in Epilepsy

Epilepsy | Cognitive Deficits | Attention Deficits

United States
Sumitomo Pharma America, Inc.

Completed

A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer (CanStem303C)

Colorectal Cancer

United States, Canada, Spain, Australia, China, Hong Kong, Israel, Czechia, France, Japan, Belgium, Germany, Netherlands, Italy, Korea, Republic of, Singapore
Pfizer's Upjohn has merged with Mylan to form Viatris...
Investigacion Farmacologica y Biofarmaceutica, S.A. de C.V.

Completed

Study Of Bioavailability Of Two Sildenafil 100mg Oral Tablet Formulations

Healthy Males

Mexico
Asan Medical Center

Unknown

Investigation of Association Between UGT1A1 Polymorphisms and Irinotecan Toxicity in Korean Patients

Gastric Cancer | Stage IV Colorectal Cancer

Korea, Republic of
Bayer
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Switching Study From Warfarin to Rivaroxaban

Venous Thrombosis

Germany
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Suspended

Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals

HIV Infection | LTBI

United States, Haiti, Botswana, Brazil, Thailand, Zimbabwe, Malawi, Peru, South Africa
University of Pittsburgh
Bristol-Myers Squibb

Withdrawn

Neoadjuvant Combination Biotherapy With Ipilimumab and Nivolumab or Nivolumab Alone

Melanoma

United States
University of Roma La Sapienza

Completed

Low Level Laser Therapy in the Treatment of Temporomandibular Joint Disorders (TMJDs) Related Pain

Temporomandibular Joint Disorders
AIO-Studien-gGmbH
Sanofi; Institut für Klinisch-Onkologische Forschung (IKF) Frankfurt

Completed

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Rectal Cancer | Rectosigmoid Cancer

Germany
National Cancer Institute (NCI)

Completed

A Randomized Multi-Intervention Trial to Inhibit Precancerous Gastric Lesions in Lingu, Shandong Province

Precancerous Gastric Lesions

China
Fondazione Italiana Linfomi - ETS

Recruiting

Shortened vs Standard Chemotherapy Combined With Immunotherapy for the Initial Treatment of Patients With High Tumor Burden Follicular Lymphoma

Follicular Lymphoma

Italy
Eli Lilly and Company

Completed

A Study of LY3202626 in Healthy Participants and Participants With Alzheimer's Disease

Alzheimer Disease | Healthy Volunteers

United States
Omar Abdelkarem Hasan

Not yet recruiting

Evaluation of Primary Congenital Glaucoma at Asyut University Hospital

Primary Congenital Glaucoma
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Terminated

Combination of Vorinostat and Bortezomib in Relapsed or Refractory T-Cell Non-Hodgkin's Lymphoma

Lymphoma

United States
Federal University of São Paulo

Unknown

Phototherapeutic Keratectomy (PTK) With Mitomycin in Adenoviral Opacities

Keratitis | Corneal Opacity

Brazil
Guilan University of Medical Sciences

Completed

To Compare Ofloxacin With Azitromycin for Pelvic Inflammatory Disease (PID) Treatment (CTO)

Pelvic Inflammatory Disease

Iran, Islamic Republic of
National Institutes of Health Clinical Center (CC)

Completed

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Healthy Volunteers

United States
French National Agency for Research on AIDS and...

Completed

Feasibility Study of a Once Daily Antiretroviral Regimen in Vietnam (ANRS 1210 VIETAR)

HIV Infection

Vietnam
Police General Hospital, Thailand

Not yet recruiting

Effectiveness of Repeated Amiodarone Dosing Regimen Versus Standard Dosing Regimen in Atrial Fibrillation Patient With Rapid Ventricular Response

Atrial Fibrillation
Gilead Sciences

Completed

COMBISTRAT: AmBisome® in Combination With Caspofungin for the Treatment of Invasive Aspergillosis

Invasive Aspergillosis

France

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