Search clinical trials for: Saline challenge

Total 12311 results

McMaster University

Not yet recruiting

Measurements of Inflammation Induced by Allergen Inhalation Challenge in Mild Allergic Asthma (MATT)

Mild Asthma

Canada
Cambridge University Hospitals NHS Foundation Trust
Imperial College London; University of Manchester

Unknown

The Effect of Extrinsic Factors on Food Allergy (Ex-Factor)

Peanut Hypersensitivity

United Kingdom
Sanaria Inc.
Swiss Tropical & Public Health Institute; Ifakara Health Research and Development...

Completed

Controlled Human Malaria Infection by Intradermal Injection of Plasmodium Falciparum Sporozoites in Tanzanian Adults

Malaria

Tanzania
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline

Unknown

Validation of the Analysis Methodology Behind the Use of Quantitative 18F-FDG PET/CT to Assess Lung Inflammation (VERIFY)

Sarcoidosis | Lung Inflammation

United Kingdom
GlaxoSmithKline
Professor Chilvers, University of Cambridge

Completed

Neutrophil Imaging in Healthy Subjects Following Lipopolysaccharide or Saline Challenge and in Subjects With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom
University Hospital, Caen

Unknown

Correlation Between ΔPP/HR and ΔSV During Fluid Challenge. (ΔPP/HRvsΔSV)

Hypovolemia

France
Sanaria Inc.
German Federal Ministry of Education and Research; German Center for Infection... and other collaborators

Completed

Sequential Optimization of Dose and Schedule of PfSPZ Vaccine

Malaria

Germany
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Intranasal Diagnostics in Food Allergy: a Feasibility Study (INDY)

Food Allergy

United Kingdom
Sanaria Inc.
Swiss Tropical & Public Health Institute; Ifakara Health Institute; Government... and other collaborators

Completed

Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea

Malaria

Equatorial Guinea
Sanaria Inc.
Swiss Tropical & Public Health Institute; Ifakara Health Institute; Medical Care... and other collaborators

Completed

Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants

Malaria

Tanzania
Sanaria Inc.
Swiss Tropical & Public Health Institute; Ifakara Health Institute; Medical Care...

Completed

Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian Adults

Malaria | Malaria,Falciparum

Tanzania
Sanaria Inc.
Fred Hutchinson Cancer Center

Completed

Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults

Malaria

United States
Sanaria Inc.
University of Maryland, Baltimore

Terminated

A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI

Malaria | Malaria,Falciparum

United States
Sanaria Inc.
Swiss Tropical & Public Health Institute; Ifakara Health Institute; Government... and other collaborators

Completed

Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea.

Malaria

Equatorial Guinea
Lund University
Food for Health Science Centre, Lund University

Completed

Acute Effects of Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects

Healthy

Sweden
Joslin Diabetes Center
ImmusanT, Inc.

Completed

Gluten Immunity and Islet Autoimmunity in Type-1 Diabetes

Type 1 Diabetes | Celiac Disease

United States
Hospital Mutua de Terrassa

Completed

Lymphocytic Enteritis and Suspected Coeliac Disease: Gluten vs Placebo

Celiac Disease | Non-celiac Gluten Sensitivity
Emory University
Centers for Disease Control and Prevention

Completed

The Mixed Meal Challenge Study

Cardiovascular Diseases | Hyperlipidemias

United States
Mahidol University

Completed

The Utility of Serum Tryptase in the Diagnosis of Shrimp- Induced Anaphylaxis

Food (Shrimp) Allergy

Thailand
The University of Texas Health Science Center,...

Recruiting

Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach

Neuropsychiatric Syndromes

United States
Virginia Commonwealth University

Completed

Chronobiology of Meal Timing: Effects on Vascular and Renal Function

Hypertension

United States
Hospices Civils de Lyon

Recruiting

A Net Ultrafiltration Challenge to Predict Preload-dependence (UF CHALLENGE) (UF CHALLENGE)

Acute Kidney Injury

France
McMaster University
St. Joseph's Healthcare Hamilton

Unknown

Effect of Allergen Challenge on Inflammation Induced by Toll-like Receptor Stimulation in a Nasal Model

Asthma

Canada
Sanaria Inc.
Swiss Tropical & Public Health Institute; Ifakara Health Institute; Tanzania...

Completed

Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults

Malaria | Plasmodium Falciparum Malaria

Tanzania
Sanaria Inc.
Radboud University Medical Center

Completed

Controlled Human Malaria Infection (CHMI) After Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis

Malaria | Plasmodium Falciparum

Netherlands
University of Palermo
Aurelio Seidita

Recruiting

Dietary Approach to Mild-to-moderate Psoriasis

Psoriasis | Gluten Sensitivity

Italy
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Study to Assess the Effect of "Eucerin AtopiControl" on Dermal Symptoms in Patients With Atopic Dermatitis

Atopic Dermatitis | Allergy Pollen

Germany
American University

Completed

Examining Outcome Expectancies and Behavioral Reinforcers Among Young Adult Smokers

Smoking Cessation

United States
University of Maryland, Baltimore
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Challenge! Adolescent Obesity Prevention (Challenge)

Obesity | Overweight

United States
University of California, Davis

Completed

Predicting Fluid Responsiveness Using Transiently Increased Intrathoracic Pressure in Mechanically Ventilated Patients

Fluid Reponsiveness

United States
Kaiser Permanente
National Institute of Mental Health (NIMH)

Recruiting

Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments (NIMBLE)

Mental Health

United States
National Institute of Allergy and Infectious Diseases...

Completed

PfSPZ Challenge in Non-immune Adults in Baltimore, USA

Plasmodium Falciparum Infection

United States
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Celiac Disease

Celiac Disease

Finland
University of Oxford

Completed

Study to Assess Efficacy of New Malaria Vaccine Candidates AdCh63 AMA1, MVA AMA1, AdCh63 MSP1, MVA MSP1, AdCh63 ME-TRAP & MVA ME-TRAP

Malaria

United Kingdom
Pontificia Universidad Catolica de Chile
Fondo Nacional de Desarrollo Científico y Tecnológico, Chile

Not yet recruiting

Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock Patients (AUSTRALIS)

Septic Shock

Chile
Oslo University Hospital
Helse Sor-Ost; Stiftelsen Helse og Rehabilitering

Recruiting

Gluten Challenge in Celiac Disease

Celiac Disease

Norway
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis (MIMS3)

Myocardial Infarction

United States
Ali A Abdulkareem

Active, not recruiting

The Potential Association of Long Non-coding RNA (NEAT1 and MALAT1) in the Process of Epithelial-mesenchymal Transition in Periodontitis

Epithelial Mesenchymal Transition | Periodontal Disease, AVDC Stage 3and 4 | Long Noncoding RNA

Iraq
University of North Texas, Denton, TX

Completed

Examining the Impact of an Online, Non-restrictive Diet Among Persons With Multiple Sclerosis

Multiple Sclerosis

United States
Centre Hospitalier Universitaire, Amiens
Centre Hospitalier Universitaire Dijon

Active, not recruiting

Comparison of 250 ml Versus 500 ml of Fluid Challenge (KOBIAS)

Oxygen Consumption | Critical Care | Fluid Challenge

France
Erasme University Hospital

Terminated

Fluid Challenges and Microcirculation (FC)

Surgery

France
Janssen Research & Development, LLC

Completed

A Study Exploring the Use of Challenge Agents in Healthy Volunteers or Participants With a Disease of Interest

Healthy

Belgium
Swinburne University of Technology
University of Sydney; University of Manchester; Brigham Young University

Completed

Evaluation of the Nextdoor KIND Challenge

Loneliness | Social Isolation

Australia
Humanitas Clinical and Research Center

Completed

Fluid Challenge Infusion and Response (REFILL)

Anesthesia, General | Cardiovascular System | Neurosurgery

Italy
Central Hospital, Nancy, France

Unknown

Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic Surgery (RELASTANCE)

Shock, Septic | Aortic Stenosis | Oliguria | Aortic Aneurysm, Abdominal | Hyperlactatemia | Aortic Aneurysm, Ruptured

France
U.S. Army Medical Research and Development Command
United States Department of Defense; Walter Reed Army Institute of Research...

Completed

Clinical Trial for the Development of a Safe Malaria Challenge Model That Can be Reproduced in Humans (Pvivax)

Plasmodium Vivax Malaria

United States
University Medical Center Groningen

Completed

FLuid Responsiveness Prediction Using EXtra Systoles

Coronary Artery Bypass Graft

Netherlands
Medical University of Warsaw
Nutricia Foundation

Unknown

Gluten for Autism Spectrum Disorders

Autism Spectrum Disorders

Poland
Hamilton Health Sciences Corporation

Completed

Role of Cigarette Smoking in Regulating Allergen-induced Early and Late Responses in Mild Asthmatics

Asthma

Canada
University of Virginia

Not yet recruiting

Alpha-gal Pork Challenge

Allergy;Food

Search clinical trials for: Saline challenge

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