Search clinical trials for: Sapropterin dihydrochloride tablets

Total 13471 results

Tasly Pharmaceutical Group Co., Ltd

Completed

Study of Jitongning Tablet to Treat Spondyloarthritis

Spondyloarthritis

China
Providence VA Medical Center
BioMarin Pharmaceutical; Lifespan

Completed

Rhode Island Diastolic Dysfunction - Heart Failure (RIDD-HF)

Heart Failure | Cardiovascular Disease

United States
Emory University

Terminated

Phenylketonuria, Oxidative Stress, and BH4

Phenylketonuria

United States
BioMarin Pharmaceutical

Completed

PKUDOS: Phenylketonuria (PKU) Demographic, Outcomes, and Safety Registry (PKUDOS)

Phenylketonuria | Hyperphenylalaninaemia

United States
New York State Psychiatric Institute
Stanley Medical Research Institute

Completed

Kuvan in People With Schizophrenia and Schizoaffective Disorder

Schizophrenia | Schizoaffective Disorder

United States
Merck KGaA, Darmstadt, Germany
Smerud Medical Research International AS; Merck Serono Norway

Completed

Response to Kuvan® in Subjects With Phenylketonuria (PKU) in a 4 Weeks Testing Period (ENDURE)

Phenylketonuria

Norway
University of Miami

Completed

Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response

Phenylketonuria

United States
BioMarin Pharmaceutical

Completed

Kuvan®'s Effect on the Cognition of Children With Phenylketonuria (KOGNITO)

Phenylketonuria

Italy, Spain, United Kingdom, Germany
University of Massachusetts, Worcester

Withdrawn

L-arginine Study for Persistent Symptoms of Schizophrenia

Schizophrenia | Schizo Affective Disorder

United States
University of California, San Diego
BioMarin Pharmaceutical

Withdrawn

Trial of Kuvan in Lesch-Nyhan Disease

Behavioral Manifestations of Lesch-Nyhan Disease

United States
Merck KGaA, Darmstadt, Germany

Completed

Phase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With Phenylketonuria

Phenylketonuria

Germany
University of Oxford
BioMarin Pharmaceutical

Unknown

Effect of 6R-BH4 Treatment in Coronary Artery Disease (OXBIO Study)

Coronary Artery Disease

United Kingdom
University of Utah
BioMarin Pharmaceutical

Completed

Study of Kuvan Treatment in Adults With GTPCH Deficiency

GTP Cyclohydrolase Deficiency

United States
Washington University School of Medicine
University of Missouri-Columbia; Northwestern University; Oregon Health and Science... and other collaborators

Terminated

Behavioral Effects of Kuvan in Children With Mild Phenylketonuria

Phenylketonuria

United States
BioMarin Pharmaceutical

Completed

Kuvan® in Phenylketonuria Patients Less Than 4 Years Old (SPARK)

Phenylketonuria

Italy, Turkey, United Kingdom, Germany, Netherlands, Slovakia, Austria, Belgium, Czechia
BioMarin Pharmaceutical

Terminated

Sapropterin on Cognitive Abilities in Young Adults With Phenylketonuria (SIGNAL)

Phenylketonuria

Italy, Switzerland
University of Missouri-Columbia
BioMarin Pharmaceutical

Completed

The Effects of Kuvan on Functional Brain Connectivity in Individuals With Phenylketonuria (PKU)

Phenylketonuria

United States
The University of Texas Health Science Center,...
BioMarin Pharmaceutical

Terminated

Bone Mineral Density in Adults With Hyperphenylalaninemia on Kuvan Therapy

Phenylketonuria | Hyperphenylalaninemia

United States
Yiling Pharmaceutical Inc.

Completed

A Single-dose Study to Investigate the Tolerance and Pharmacokinetics of Finamine Tablets in China

Parkinson Disease

China
Universidade do Porto
BioMarin Pharmaceutical; Centro Hospitalar do Porto

Completed

Nutritional Status in Phenylketonuria (TNSPKU)

Phenylketonurias

Portugal
Haisco Pharmaceutical Group Co., Ltd.
The Fourth Hospital of Hebei Medical University

Recruiting

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK16149 Capsules and Metformin Hydrochloride Tablets

Diabetic Neuropathies | Diabetic Neuropathy Peripheral

China
Washington University School of Medicine
University of Missouri-Columbia; BioMarin Pharmaceutical

Completed

Sapropterin in Individuals With Phenylketonuria

Phenylketonuria

United States
The Children's Health Council
BioMarin Pharmaceutical

Completed

Sapropterin as a Treatment for Autistic Disorder

Autistic Disorder

United States
Fundacion Clinic per a la Recerca Biomédica

Completed

Randomized Controlled Trial to Assess the Effects of Sapropterin on Hepatic and Systemic Hemodynamics in Patients With Liver Cirrhosis and Portal Hypertension

Liver Cirrhosis | Portal Hypertension

Spain
The National Institutes of Pharmaceutical R&D Co...

Completed

A Safety, Tolerability, and Pharmacokinetic Study of NIP292 in Healthy Normal Subjects

Idiopathic Pulmonary Fibrosis

United States
The Children's Health Council
BioMarin Pharmaceutical

Completed

Open-Label Extension Study of Kuvan for Autism

Autistic Disorder

United States
Sunshine Lake Pharma Co., Ltd.

Completed

The Tolerability , Pharmacokinetics and Pharmacodynamics Study of HEC96719 Tablets in Healthy Adult Subjects

Nonalcoholic Steatohepatitis (NASH)

China
University Hospitals Cleveland Medical Center
BioMarin Pharmaceutical

Completed

The Effectiveness of Kuvan in Amish PKU Patients

Phenylketonuria

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Study of Jaktinib In Patients With Myelofibrosis Who Were Relapsed or Refractory of Ruxolitinib Treatment.

Myelofibrosis

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

An Efficacy and Safety Study of Jaktinib Hydrochloride Tablets in the Treatment of Severe Novel Coronavirus Pneumonia

Novel COVID-19-Infected Pneumonia

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Jaktinib Hydrochloride Tablets in Intermediate-risk and High-risk Myelofibrosis.

Myelofibrosis

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Study to Evaluate the Safety and Efficacy ofJaktinib Hydrochloride Tablets in Severe Alopecia Areata

Alopecia Areata

China
Zhejiang Huahai Pharmaceutical Co., Ltd.

Completed

To Explore the Safety and Efficacy of Hypidone Hydrochloride Tablets in Treatment of Patients With MDD

Major Depressive Disorder

China
Nanjing Sanhome Pharmaceutical, Co., Ltd.

Unknown

SH229 Tablets Combined With Daclatasvir Dihydrochloride Tablets in Treatment Adult Patients With Chronic Hepatitis C

Hepatitis C, Chronic

China
Atridia Pty Ltd.

Completed

A Trial of HRS-7085 Tablet in Healthy Participants With and Without Food Effect.

Inflammatory Bowel Disease

Australia
Lupin Ltd.

Completed

Bioequivalence Study of Ropinirole Hydrochloride CR 2mg Tablets of Lupin Limited, India, With REQUIP XL of GlaxoSmithKline Research Triangle Park, in Healthy, Adult, Male, Subjects Under Fasting Conditions

Pharmacokinetic Study

India
Abbott

Recruiting

Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia

Functional Dyspepsia

Malaysia, Armenia
West China Hospital

Not yet recruiting

BH4 in the Prevention and Treatment of Radiation-induced Skin Reactions for Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma)

Head and Neck Squamous Cell Carcinoma
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

A Study of Jaktinib Hydrochloride Tablets in the Treatment of Severe Novel Coronavirus Pneumonia (COVID-19)

Novel COVID-19-Infected Pneumonia

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Healthy Subject

Depression
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Healthy Subjects

Depression

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Withdrawn

Efficacy and Safety of Jaktinib in Participants With Severe Novel Coronavirus Pneumonia(COVID-19) (COVID-19)

COVID-19 | Pneumonia

China
Li Peng
Betta Pharmaceuticals Co., Ltd.

Completed

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors (Icotinib)

Neurofibromatosis Type 2 | Vestibular Schwannoma

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

A Study of Jaktinib for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease.

Acute Graft-Versus-Host Disease

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Comparative Study on Pharmacokinetics of Two Formulations of Jaktinib in Healthy Adults Under Fasting Conditions

Myelofibrosis

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Pharmacokinetics Of Jaktinib In Subjects With Hepatic Impairment And Normal Hepatic Function

Hepatic Insufficiency | Healthy Subjects

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Jaktinib for the Treatment of Ruxolitinib Intolerance of Myelofibrosis

Primary Myelofibrosis (PMF) | Post-polycythemia Vera Myelofibrosis(Post-PV MF) | Post-essential Thrombocythemia Myelofibrosis(Post-ET MF)

China
Haisco Pharmaceutical Group Co., Ltd.

Completed

Study of Acetyllevocarnitine Hydrochloride Tablets in Chinese Patients With Paresthesias Caused by DPN

Paresthesia | Diabetic Peripheral Neuropathy (DPN)

China
Zhejiang Huahai Pharmaceutical Co., Ltd.

Completed

Study to Explore the Effective Doses and to Assess the Safety and Efficacy of Hypidone Hydrochloride Tablets

Major Depressive Disorder

China
Lexicon Pharmaceuticals

Completed

A Multi-Center Trial to Determine the Safety and Efficacy of LX1033 in Subjects With Diarrhea-Predominant Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States

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