Search clinical trials for: Saxagliptin/Metformin XR FDC

Total 367 results

Mylan Pharmaceuticals Inc

Completed

Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg

Healthy

United States
Teva Pharmaceuticals USA

Completed

Metformin ER 750 mg Tablets, Fed

Healthy

Canada
Mylan Pharmaceuticals Inc

Completed

Fasting BE Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
Teva Pharmaceuticals USA

Completed

Metformin ER 750 mg Tablets, Fasting

Healthy

Canada
AstraZeneca
Bristol-Myers Squibb

Completed

To Compare the Similarity of a Combination Dapagliflozin/Metformin Tablet With the Two Drugs Administered Separately

Type 2 Diabetes Mellitus

United Kingdom
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 750 mg and Glucophage® XR Tablets 750 mg

Healthy

United States
AstraZeneca

Completed

Efficacy and Safety Study of Saxagliptin + Metformin Immediate Release (IR) Versus Metformin IR Alone in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States, Puerto Rico, Germany, Hungary
Oregon Health and Science University

Completed

Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetics Study of CPL207280 Compound in Healthy Volunteers.

Healthy Volunteers

Poland
Aarhus University Hospital

Completed

Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure (METRONOME)

Heart Failure, Systolic

Denmark
Shahid Beheshti University of Medical Sciences

Recruiting

Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients

Polycystic Ovary Syndrome | Infertility | ART

Iran, Islamic Republic of
Merck Sharp & Dohme LLC

Completed

A Study of the Effects of Sitagliptin (MK0431) and Metformin on Incretin Hormone Concentrations (0431-050)(COMPLETED)

Type 2 Diabetes
Azienda Ospedaliero-Universitaria di Parma

Active, not recruiting

Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs (MIRACLE)

Newly Diagnosed Type 2 Diabetes

Italy
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)

Type 2 Diabetes Mellitus
LG Life Sciences

Completed

Food-Effect Bioavailability Study of FDC(Gemigliptin/Metformin HCl Sustained Release) 50/1000mg(25/500mg x 2tablets)

Type 2 Diabetes

Korea, Republic of
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance

Metabolic Syndrome | Insulin Resistance | Type 2 Diabetes

United States
Joint Stock Company "Farmak"

Completed

Fed Bioequivalence Study of 2 Metformin 500 mg Prolongued Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the Safety and Efficacy of the Addition of Omarigliptin (MK-3102) Compared With the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)

Type 2 Diabetes
Bio-innova Co., Ltd

Not yet recruiting

Sitagliptin and Metformin Hydrochloride Tablets 50 mg/1000 mg Relative to Originator

Healthy Subjects
Merck Sharp & Dohme LLC

Completed

Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189)

Diabetes Mellitus, Non-Insulin-Dependent
Merck Sharp & Dohme LLC

Completed

A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)

Type 2 Diabetes Mellitus
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant (EPIK-B4)

Breast Cancer

Malaysia, United States
ikfe-CRO GmbH
AstraZeneca; IKFE Institute for Clinical Research and Development

Unknown

Investigation of a Switch From Insulin Therapy to a Metformin & Saxagliptin Combination in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Germany
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fasting Condition

Fasting

India
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
Takeda

Completed

Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes

Diabetes Mellitus

China, Taiwan, Korea, Republic of, Malaysia
University of Chicago

Completed

A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors

Lymphoma | Breast Neoplasms | Lung Neoplasms | Cancer of Liver | Cancer of Kidney

United States
Genuine Research Center, Egypt
Eva Pharma

Completed

Bioequivalence Study of of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands)

Healthy

Egypt
Mayo Clinic
Abbott Medical Devices

Completed

Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)

Polycystic Ovary Syndrome

United States
University of Arizona
National Cancer Institute (NCI)

Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Oral Leukoplakia | Erythroplakia

United States, Canada
National Cancer Institute (NCI)

Recruiting

Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer

Lung Carcinoma

United States, Canada
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
The Affiliated Hospital of Qingdao University

Completed

Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects

Healthy Subjects

China
Joint Stock Company "Farmak"

Completed

Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Woman's
AstraZeneca

Completed

Dapagliflozin and Metformin,Alone and in Combination, in Overweight/Obese Prior GDM Women (DAPA-GDM)

Diabetes Prevention in Women After GDM Who Are at High-risk

United States
Takeda

Completed

Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.

Diabetes Mellitus

United States, Chile, Mexico, Puerto Rico
Shanghai 10th People's Hospital

Completed

Non-alcoholic Fatty Liver Disease and Its Treatment

NAFLD
Boehringer Ingelheim

Completed

A Study in Healthy Humans to Assess the Relative Bioavailability of One Fixed-dose Combination Tablet Empagliflozin/Metformin Versus Jardiance® Tablet and Glifage® Tablet Administered Together (InPedILD®)

Healthy

Brazil
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Non-fasting Conditions

Healthy

United States
University of Minnesota

Withdrawn

Pioglitazone Therapy in Obese Children With Insulin Resistance: A Randomized, Controlled Pilot Study

Obesity | Insulin Resistance
AstraZeneca
Bristol-Myers Squibb

Completed

Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State

Type 2 Diabetes Mellitus (T2DM)

United States
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fed Condition

Fasting

India
University of Pisa
Merck Sharp & Dohme LLC

Completed

Metformin and Sitagliptin in Women With Previous Gestational Diabetes

Pre-diabetes

Italy
University of Campinas, Brazil

Unknown

Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma (METDEXA-MM)

Multiple Myeloma

Brazil
AstraZeneca
Bristol-Myers Squibb

Completed

An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets

Type 2 Diabetes

Korea, Republic of, United States, Mexico, Puerto Rico, Philippines, Russian Federation, Ukraine
AstraZeneca

Completed

Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

Diabetes Mellitus, Type 2

United States, Canada, Mexico, Puerto Rico, Taiwan, Australia
Shandong Provincial Hospital
Chinese Medical Association

Unknown

Effect of Saxagliptin on Pre-Diabetes Mellitus and Obesity

Prediabetes

China
St. Jude Children's Research Hospital
National Cancer Institute (NCI); Conquer Cancer Foundation; St. Baldrick's Foundation

Recruiting

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

PreDiabetes | Adult Children

United States
Chong Kun Dang Pharmaceutical

Completed

A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.5/1000 mg in Healthy Male Volunteers

Diabetes Mellitus, Type II

Korea, Republic of

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