Search clinical trials for: Sch 39166

Total 2344 results

National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

HIV Infection | Hepatocellular Carcinoma | Non-Hodgkin Lymphoma | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Kaposi Sarcoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable... and other conditions

United States
Northwestern University
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma

United States
National Institute of Neurological Disorders and...

Completed

Physiological Investigations of Movement Disorders

Parkinson's Disease | Movement Disorders | Dystonia | Tic Disorders | Tourette's Syndrome

United States
Scynexis, Inc.

Completed

Phase 3 Study of Oral Ibrexafungerp (SCY-078) Vs. Placebo in Subjects With Recurrent Vulvovaginal Candidiasis (VVC) (CANDLE)

Recurrent Vulvovaginal Candidiasis

United States
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Efficacy, Safety and Dose-Response Study Followed by Open-Label Study of Lofexidine Treatment of Opioid Withdrawal

Opioid Dependence | Acute Opioid Withdrawal Syndrome

United States
M.D. Anderson Cancer Center

Completed

Allogeneic Transplantation in Patients With Cutaneous T-Cell Lymphoma

Lymphoma | Disorder Related to Bone Marrow Transplantation

United States
Astellas Pharma Global Development, Inc.

Completed

Registry of Patients Treated With Systemic Mold-Active Triazoles

Invasive Fungal Infection

United States
Hearn Jay Cho
Bristol-Myers Squibb

Completed

Elotuzumab in Autologous Stem Cell Transplantation (ASCT) and Lenalidomide Maintenance for Multiple Myeloma

Multiple Myeloma

United States
Alcon Research

Completed

A Comfort Study of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination, Brinzolamide 1% and Brimonidine 0.2%

Ocular Hypertension | Open-Angle Glaucoma
NeuroDerm Ltd.
Michael J. Fox Foundation for Parkinson's Research

Completed

A Safety, Tolerability, and Pharmacokinetic Study of ND0612 Delivered as a Continuous Subcutaneous in Parkinson's Disease Patients

Parkinson's Disease

Israel
Eli Lilly and Company

Completed

The Forteo Alendronate Comparator Trial (FACT)

Osteoporosis

United States, Brazil, Mexico, Puerto Rico
TaiMed Biologics Inc.
Bill and Melinda Gates Foundation; Aaron Diamond AIDS Research Center

Completed

Safety Study of Ibalizumab Subcutaneous Injection in Healthy Volunteers (TMB-108)

Prevention of Infection With HIV-1

United States
Marc Breton
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Tandem... and other collaborators

Completed

The Pediatric Artificial Pancreas (PEDAP) Trial of Control-IQ Technology in Young Children in Type 1 Diabetes

Type 1 Diabetes

United States
Amgen

Completed

Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates

Bone Metastases in Men With Hormone-Refractory Prostate Cancer | Bone Metastases in Subjects With Advanced Breast Cancer | Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma
Heidelberg University

Unknown

Prospective Trial on Immunochemotherapy Plus Autologous Stem Cell Transplantation (SCT) and Allogenic SCT in Primary Mantle-Cell-Lymphoma (HD-MCL2003)

Mantle-Cell Lymphoma

Germany
Roswell Park Cancer Institute

Recruiting

Non-chemotherapeutic Interventions for the Improvement of Quality of Life and Immune Function in Patients With Multiple Myeloma

Plasma Cell Myeloma | Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | Smoldering Plasma Cell Myeloma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer

Stage IV Pancreatic Cancer AJCC v6 and v7 | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Pancreatic Ductal Adenocarcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy

United States
M.D. Anderson Cancer Center

Active, not recruiting

Pembrolizumab and Stereotactic Body Radiation Therapy or Non-Stereotactic Wide-Field Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer

Malignant Solid Neoplasm | Metastatic Lung Non-Small Cell Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

Glioblastoma | Gliosarcoma | Supratentorial Glioblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Central Nervous System Neoplasm | Spinal Cord Neoplasm

United States
Organon and Co

Terminated

Safety and Efficacy of Quadriderme® in the Treatment of Impetiginous Eczema (Study P05134AM4)

Skin Diseases, Eczematous | Dermatitis, Atopic | Eczema, Atopic
National Cancer Institute (NCI)

Not yet recruiting

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Undifferentiated Pleomorphic Sarcoma | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study (SAMURAI)

Metastatic Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Unresectable Renal Cell Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab in Treating Patients With Desmoplastic Melanoma That Can or Cannot Be Removed by Surgery

Desmoplastic Melanoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Pembrolizumab and Paricalcitol With or Without Chemotherapy in Patients With Pancreatic Cancer That Can Be Removed by Surgery

Resectable Pancreatic Carcinoma | Stage I Pancreatic Cancer AJCC v6 and v7 | Stage IA Pancreatic Cancer AJCC v6 and v7 | Stage IB Pancreatic Cancer AJCC v6 and v7 | Stage II Pancreatic Cancer AJCC v6 and v7 | Stage IIA Pancreatic Cancer AJCC v6 and v7 | Stage IIB Pancreatic Cancer AJCC v6 and v7

United States
National Cancer Institute (NCI)

Completed

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Untreated Childhood Brain Stem Glioma | Giant Cell Glioblastoma | Untreated Childhood Anaplastic Astrocytoma | Untreated Childhood Giant Cell Glioblastoma | Untreated Childhood Glioblastoma | Untreated Childhood Gliosarcoma | Brain Stem Glioma | Untreated... and other conditions

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Terminated

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States, Canada
National Institute of Allergy and Infectious Diseases...

Completed

The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs

HIV Infections | Lipodystrophy | HIV Seronegativity

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Auto-Allo Tandem Stem Cell Transplantation for Patients With Multiple Myeloma

Multiple Myeloma

Germany
Katarina Kos
University of Exeter

Terminated

Incretin and KATP Channels

Healthy Subjects

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Arterial Disease Multifactorial Intervention Trial (ADMIT)

Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Arterial Occlusive Diseases | Diabetes Mellitus
University Medicine Greifswald

Completed

Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects (LOP-MNTX-2009)

Intestinal Obstruction

Germany
Bayer

Completed

Cycle Control and Safety of E2-DRSP

Contraceptive, Oral, Hormonal

Germany
Kazakhstan's Medical University "KSPH"
Vyacheslav Notanovich Lokshin; Nurgalieva Zhanar Zhenisovna; Manzhuova Lyazzat... and other collaborators

Completed

Health Status of Children Born After Assisted Reproductive Technologies

Child Development | Health Status | Children Born After Assisted Reproductive Technologies

Kazakhstan
Alexion Pharmaceuticals
Celerion

Completed

A Study of the Cardiac Effects of ALXN2050 in Healthy Adults

Healthy

United States
Rutgers, The State University of New Jersey
National Institute on Drug Abuse (NIDA)

Completed

Heart Rate Variability Biofeedback for Smoking Cessation (HRVB-SCT)

Tobacco Smoking

United States
INTRuST, Post-Traumatic Stress Disorder - Traumatic...
U.S. Army Medical Research and Development Command

Terminated

Cognitive REmediation After Trauma Exposure Trial = CREATE Trial (CREATE)

Traumatic Brain Injury | Posttraumatic Stress Disorder

United States
New York Institute of Technology
Stony Brook University

Unknown

Vitamin B6, B12, Folic Acid and Exercise in Parkinson's Disease

Parkinson's Disease

United States
Columbia University

Completed

Intermediate or Prophylactic-Dose Anticoagulation for Venous or Arterial Thromboembolism in Severe COVID-19 (IMPROVE)

COVID-19 | Venous Thromboses | Arterial Thrombosis

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

MRD/Risk-oriented Therapy of Adult Ph- ALL Including Pegylated Asparaginase and Lineage-targeted Methotrexate (LAL1913)

Secondary | De Novo | Untreated Philadelphia Positive Acute Lymphoblastic Leukemia | Low-dose Corticosteroids Pretreatment

Italy
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Multiple Doses of Neural Stem Cell Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
Bausch Health Americas, Inc.

Completed

Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan

Healthy Adults

United States
New Approaches to Neuroblastoma Therapy Consortium
Nationwide Children's Hospital; United Therapeutics

Active, not recruiting

Immunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK Cells

Neuroblastoma

United States
Yonsei University

Unknown

Effect of Heated Breathing Circuit on Intraoperative Core Temperature and Systemic Inflammation After Brain Surgery: a Prospective Randomized Study

Patients Scheduled for Brain Surgery

Korea, Republic of
University of Bergen
Haukeland University Hospital; Helse Vest; Muhimbili University of Health and...

Completed

Impact of Cotrimoxazole Use in Immunocompetent HIV Patients on Carriage of Antimicrobial Resistant Bacteria (CoTrimResist)

Opportunistic Infections | HIV-1-infection | Antibiotic Side Effect | Pneumocystis Pneumonia | Preventive Therapy

Tanzania
Oswaldo Cruz Foundation
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Recruiting

Safety and Efficacy of Decentralized HCV Treatment vs Standard-of-Care in Rio de Janeiro (Brazil) (HCVPCL05/20)

Hepatitis C

Brazil
Bayer

Completed

Efficacy and Safety of Two Flexible Extended Regimens of BAY86-5300 (SH T00186D) in Comparison With the Conventional Regimen of YAZ

Contraception | Ovulation Inhibition | Contraceptives, Oral

United States
Bristol-Myers Squibb

Completed

Efficacy, Pharmacokinetics, Safety, and Immunogenicity Study of Abatacept Administered Subcutaneously to Treat Rheumatoid Arthritis in Japanese Patients

Rheumatoid Arthritis

Japan
BlueWillow Biologics
Porton Biopharma Ltd.

Completed

A Safety and Immunogenicity of Intranasal Nanoemulsion Adjuvanted Recombinant Anthrax Vaccine in Healthy Adults (IN NE-rPA)

Anthrax

United States

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