Search clinical trials for: Sebelipase alfa 1 mg/kg

Total 2167 results

Medicines Development for Global Health
World Health Organization

Completed

Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection

Onchocerciasis

Ghana
Hospital de Manises
Merck Sharp & Dohme LLC; Hospital Arnau de Vilanova; Hospital Universitario La... and other collaborators

Unknown

Optimization of Golimumab Treatment in Ulcerative Colitis

Colitis, Ulcerative

Spain
Genor Biopharma Co., Ltd.

Recruiting

Phase I Clinical Trial in Chinese Patients of Advanced and (or) Recurrent Solid Tumor/Lymphoma (GB226)

Lymphoma | Advanced Solid Tumor | Recurrent Solid Tumor | Recurrent Lymphocyte Depleted Classical Hodgkin Lymphoma

China
The Cleveland Clinic
Merck Sharp & Dohme LLC

Not yet recruiting

Sugammadex Vs Neostigmine in Reversing Neuromuscular Blocks in Outpatient ERCP. A Randomized, Double-Blinded Trial

Neuromuscular Blocks
Celgene

Completed

2-part Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of CC-220 & Effect of Food on CC-220 in Healthy Subjects

Healthy

United States
Nocion Therapeutics

Completed

Placebo-controlled, Single and Multiple Dose Study in Healthy Volunteers and Refractory Chronic Cough Patients to Assess the Safety, Tolerability, and Pharmacokinetics of Two Formulations of NTX-1175

Refractory Chronic Cough

United States
Pfizer

Completed

First Safety Study in Humans of a Single Dose of CPG 52364

Healthy Volunteers

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Efficacy and Safety of MK2578 for the Treatment of Anemia in Patients With Kidney Disease (MK2578-003-AM03-EXT12)

Anemia | Chronic Kidney Disease
Janssen Research & Development, LLC

Completed

A Study to Compare CNTO 328 (Anti-IL-6 Monoclonal Antibody) and VELCADE-Melphalan-Prednisone (VMP) With VMP Alone in Previously Untreated Multiple Myeloma Patients

Multiple Myeloma

United States, Australia, France, Spain, Israel, India, Romania, Korea, Republic of, Singapore, Russian Federation, Poland
H. Lundbeck A/S

Terminated

Study With Lu AF11167 for the Treatment of Negative Symptoms in Patients With Schizophrenia

Schizophrenia

Bulgaria, Czechia, Estonia, Germany, Hungary, Latvia, Poland, Ukraine
Medical College of Wisconsin

Not yet recruiting

Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma

Multiple Myeloma
Shire

Completed

Short Bowel Syndrome Research Study for Children Up To 17 Years of Age on Parenteral Nutrition

Short Bowel Syndrome

United States, Canada, Finland, Belgium, Italy, United Kingdom, Germany
Ablynx

Terminated

Evaluation of ALX-0171 in Japanese Children Hospitalized for Respiratory Syncytial Virus Lower Respiratory Tract Infection

Respiratory Syncytial Virus Lower Respiratory Tract Infection

Japan
Novartis Pharmaceuticals

Withdrawn

A Study to Evaluate the Effects of Indacaterol Maleate (QAB149) as a New Formulation in the EPIC Test Fixture

Asthma
Pila Pharma

Completed

A Single-dose Trial to Investigate the Safety and Tolerability of XEN-D0501 in Patients With Diabetes Mellitus Type 2

Diabetes Mellitus, Type 2

Denmark
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Phase I Study of Direct Coagulation Factor Xa Inhibitor SYHA136 Tablets in Chinese Healthy Volunteers

Venous Thrombosis
GlaxoSmithKline

Completed

Safety and Efficacy Study in Patients With Major Depressive Disorder

Depressive Disorder

Russian Federation
Zydus Therapeutics Inc.

Completed

Saroglitazar Magnesium in Patients With Nonalcoholic Fatty Liver Disease and/or Nonalcoholic Steatohepatitis (EVIDENCES IV)

Nonalcoholic Steatohepatitis | Non-Alcoholic Fatty Liver Disease

United States
Cara Therapeutics, Inc.

Completed

A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee

Osteoarthritis

United States
University of Colorado, Denver
Children's Hospital Colorado

Active, not recruiting

Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma

Diffuse Intrinsic Pontine Glioma

United States
Hoffmann-La Roche
Tempest Therapeutics; Adagene Inc; Immune-Onc Therapeutics; NiKang Therapeutics...

Recruiting

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Advanced Liver Cancers

Korea, Republic of, Taiwan, United States, Israel, China, France, New Zealand
Baxalta now part of Shire
Alzheimer's Disease Cooperative Study (ADCS)

Completed

A Phase 3 Study Evaluating Safety and Effectiveness of Immune Globulin Intravenous (IGIV 10%) for the Treatment of Mild-to-Moderate Alzheimer´s Disease

Alzheimer´s Disease

United States, Canada
MediBeacon

Completed

Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types

Acute Kidney Injury

United States
Geron Corporation

Completed

Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor

Myelofibrosis

United States, France, Italy, United Kingdom, Belgium, Germany, Taiwan, Spain, Israel, Korea, Republic of, Canada
Herlev Hospital

Completed

The Laparotomy Study

Gastrointestinal Cancer

Denmark
Stanford University

Completed

Pre-operative Prophylaxis With Vancomycin and Cefazolin in Pediatric Cardiovascular Surgery Patients

Aortic Valve Disorder | Congenital Heart Diseases

United States
University Hospital, Montpellier

Completed

Transfusion Savings in Heart Surgery: Impact of Individual Strategy by Erythropoietin and Metabolic Adjustment (ScvO2) (BLOOCOST)

Cardiac Surgery | Transfusion | Perioperative Anemia

France
Radboud University Medical Center
London School of Hygiene and Tropical Medicine; Kilimanjaro Christian Medical...

Completed

Mass-Drug Administration to Reduce Malaria Transmission (MDATRANS)

Malaria, Falciparum

Tanzania
Rune Rasmussen

Completed

Effects of Prostacyclin Infusion on Cerebral Vessels and Metabolism in Patients With Subarachnoid Haemorrhage

Subarachnoid Hemorrhage

Denmark
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Vyne Therapeutics Inc.

Terminated

A Study of MK0594 in Patients With Alcohol Dependence (0594-020)

Alcohol Dependence
Handok Inc.

Completed

Dose Proportionality Study Comparing Amaryl-M 1/500 mg and Amaryl-M 2/500 mg

Healthy
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD5718 After Single and Multiple Ascending Dose Administration to Healthy Male Subjects

Cardiovascular Disease | Healthy Male Subjects

United Kingdom
Al-Azhar University

Recruiting

Safety and Efficacy of Scheduled Intravesical Gemcitabine Versus Intravesical BCG for Intermediate and High Risk Non Muscle Invasive Bladder Cancer: A Prospective, Randomized Study

Non-muscle-invasive Bladder Cancer

Egypt
University of Pittsburgh
National Cancer Institute (NCI)

Completed

Study of PEG-Intron for Plexiform Neurofibromas

Plexiform Neurofibroma

United States
National Institute of Cancerología

Recruiting

Evaluation of Concomitant Chemo-radiotherapy With Cisplatine vs Gemcitabin in Locally Advanced Cervicouterine Cancer (MICHELE)

Gemcitabine | Locally Advanced Cervical Cancer | Chemo-radiotherapy

Mexico
U.S. Army Medical Research and Development Command
National Institute of Allergy and Infectious Diseases (NIAID); Duke University and other collaborators

Not yet recruiting

Evaluation of Safety and Immunogenicity of Ad26.Mos4.HIV and CH505 TF chTrimer Combination in Healthy Adults (RV591)

Human Immunodeficiency Virus

Uganda
Yale University

Active, not recruiting

Fixed Order, Open-Label, Dose-Escalation Study of DMT in Humans

Depression | Major Depressive Disorder

United States
London School of Hygiene and Tropical Medicine
University Medical Center Nijmegen; Centre national de recherche et de formation...

Completed

Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM)

Malaria

Burkina Faso
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
ANRS, Emerging Infectious Diseases
Flamel Technologies

Unknown

Study Comparing the Tolerability and Viral Reduction of the Combination of IFN a-2b XL + Ribavirin Versus Peg IFN a-2b + Ribavirin in Patients With Chronic Hepatitis C, Genotype 1 or 4 (COAT IFN)

Chronic Hepatitis C

France
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949

Healthy Subjects

Netherlands
Centocor, Inc.

Completed

A Study of Safety and Effectiveness of Ustekinumab in Patients With Moderate to Severe Active Crohn's Disease Who Have Been Previously Treated With Anti-TNF Therapy

Crohn's Disease

United States, France, United Kingdom, Germany, Spain, Belgium, Israel, Australia, Canada, Netherlands, New Zealand, Austria
BioLineRx, Ltd.
Celerion

Completed

Study to Investigate the Effect of BL-8040 (Motixafortide) on the QTc Interval in Healthy Subjects

Healthy Subjects

United States
SUNHO（China）BioPharmaceutical CO., Ltd.

Recruiting

Clinical Study of IAH0968 in Patients With HER2-positive Advanced Solid Tumors

Advanced Solid Tumor

China
University of Wisconsin, Madison
Wisconsin Alumni Research Foundation

Completed

Fruit-based Chewing Gums for Improving Oral Health

Oral Health

United States
Centro Nacional de Investigaciones Oncologicas...
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina...

Unknown

PRORADIUM: Prospective Multi-centre Study of Prognostic Factors in mCRPC Patients Treated With Radium-223. (PRORADIUM)

Advanced Prostate Cancer | Castration Resistant | Radium 223

Spain
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates; Triangle Biostatistics

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Spain, Canada, Australia, United Kingdom, Germany, Netherlands, Belgium, Austria, France
GlaxoSmithKline

Completed

Relative Bioavailability Study of Marketed and Lower Dose Ambrisentan in Healthy Adult Participants

Hypertension, Pulmonary

United Kingdom
Laboratorios Leti, S.L.

Completed

Safety, Tolerability and Efficacy of the Depigmented Modified Allergen Extract of Two Mites in Subjects With Allergic Rhinitis or Rhinoconjunctivitis, With Controlled Allergic Asthma

Asthma | Rhinitis | Rhinoconjunctivitis

Spain

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