Search clinical trials for: Serotonin 5-HT3 Receptor Antagonists

Total 11650 results

Loyola University

Recruiting

Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery

Pain, Postoperative

United States
Merck Sharp & Dohme LLC

Completed

A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005)

Infectious Disease
Peking University People's Hospital
First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

Unknown

Yiqi Huoxue Huatan Granule for Reducing Mortality in COPD With Chronic Respiratory Failure

Chronic Obstructive Pulmonary Disease | Chronic Respiratory Failure

China
Celgene

Completed

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

Healthy Volunteer

United States
Assiut University

Unknown

Management of Supraventricular Tachycardia of Children

Supraventricular Tachycardia
GlaxoSmithKline

Completed

Outcomes and Costs Associated With Initiating Maintenance Treatment With Fluticasone Propionate 250mcg/Salmeterol Xinafoate 50mcg Combination (FSC) Versus Anticholinergics Including Tiotropium (TIO) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive
First Affiliated Hospital Xi'an Jiaotong University

Unknown

Effects of Different Doses of Dexmedetomidine on Postoperative Cognitive Dysfunction in Elderly Hypertensive Patients

Postoperative Cognitive Dysfunction
GlaxoSmithKline

Completed

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Healthy Subjects | Anaemia

Australia
King Faisal University

Completed

Aminophylline and Cognitive Function After Sevoflurane Anaesthesia

Anaesthesia

Saudi Arabia
Hospital for Special Surgery, New York

Completed

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery. (LMA vs Spinal)

Pain | Spinal Anesthesia | Postoperative Nausea and Vomiting | General Anesthesia | Nerve Block

United States
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
Fox Chase Cancer Center

Active, not recruiting

Risk Enabled Therapy After Initiating Neoadjuvant Chemotherapy for Bladder Cancer (RETAIN)

Urothelial Carcinoma of the Bladder

United States
University of Alexandria

Completed

Efficacy of Neural Prolotherapy for Treatment of Anserine Bursitis "NPCAB"

Anserine Bursitis

Egypt
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Administration of Tadalafil in Conjunction With Lenalidomide and Dexamethasone in Patients With Multiple Myeloma

Multiple Myeloma

United States
Medical College of Wisconsin
FDA Office of Orphan Products Development

Terminated

Clinical Trial of Vincristine vs. Prednisolone for Treatment of Complicated Hemangiomas

Hemangioma

United States
Suez Canal University

Not yet recruiting

Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone

Upper Extremity Injury
AstraZeneca

Recruiting

A Study to Investigate the Effects of PT027 (Budesonide/Albuterol Sulfate) Metered-dose Inhaler Compared With Placebo on Exercise-Induced Bronchoconstriction in Adult Patients With Asthma (BREATH)

Asthma, Exercise-Induced

Russian Federation
AstraZeneca

Not yet recruiting

A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs (EXCEED)

Pancreatic Cancer
Eurofarma Laboratorios S.A.

Recruiting

A Multicenter, Randomized, Parallel, Two-Period, Non-Inferiority Study of EurofarmavsAlenia in Asthma and COPD Treatment (ESPIRE)

Asthma Copd

Brazil
Peking University First Hospital

Completed

Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Postoperative Analgesia

Dexmedetomidine | Postoperative Analgesia | S-ketamine | Sufentanil | Scoliosis Correction

China
University of Chile

Completed

Dexametasone Versus Dexametasone Plus Dexmedetomidine in Nerve Blocks

Analgesia | Pain, Acute | Upper Extremity Injury

Chile
Arlyne Thung

Completed

A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients

Adenoid Hypertrophy

United States
Chiesi Farmaceutici S.p.A.

Completed

EFFICACY AND TOLERABILITY OF BECLOMETHASONE DIPROPIONATE 100 µg + FORMOTEROL 6 µg pMDI VIA HFA-134a vs. FLUTICASONE 125 µg + SALMETEROL 25 µg pMDI

Bronchial Asthma

Poland, Ukraine
Inje University

Completed

Dexmedetomidine-ketamine in Femur Proximal Fracture Patients

Pain

Korea, Republic of
Milton S. Hershey Medical Center
GlaxoSmithKline

Completed

Comparing Fluticasone-salmeterol in Chronic Obstructive Pulmonary Disease (COPD) and Sleep

COPD

United States
GlaxoSmithKline

Completed

Comparative Study of Umeclidinium/Vilanterol (UMEC/VI) in a Fixed Dose Combination With Indacaterol Plus Tiotropium

Pulmonary Disease, Chronic Obstructive

Argentina, Germany, Romania, Russian Federation, Estonia, Peru, Poland, France, Chile, Hungary, Italy, Slovakia
University of Wisconsin, Madison
GlaxoSmithKline

Completed

The Effect of Salmeterol on Eosinophil (EOS) Function

Allergic Asthma

United States
GlaxoSmithKline

Completed

Fluticasone Propionate/Salmeterol Combination 250/50 DISKUS in the Exercise Endurance Time in Patients With Chronic Obstructive Pulmonary Disease (ESWT)

Pulmonary Disease, Chronic Obstructive

Canada, United States
Cairo University

Completed

Caudal Combination of Dexamethasone and/or Dexmedetomidine to Bupivacaine in Pediatric Hypospadias Surgery

Caudal Block
GlaxoSmithKline

Completed

Outcomes for Chronic Obstructive Pulmonary Disease Moderate Exacerbators Initiating Treatment

Pulmonary Disease, Chronic Obstructive
Chiesi Farmaceutici S.p.A.

Completed

A Study to Evaluate the Acute Bronchodilator Effect of CHF1535 NEXThaler

Asthma

United Kingdom
GlaxoSmithKline

Completed

Chronic Obstructive Pulmonary Disease Endpoints Study

Pulmonary Disease, Chronic Obstructive

Russian Federation, United States, Estonia, Chile
Rockefeller University
Merck Sharp & Dohme LLC; Pfizer; Aaron Diamond AIDS Research Center

Completed

Standard Antiretroviral v. Multi-class Therapy in Acutely HIV-1 Infected Antiretroviral-Naïve Subjects (ADARC 2007-01)

HIV Infections

United States
Università degli Studi di Ferrara

Completed

Prn Budesonide/Formoterol Versus Regular Budesonide/Formoterol Plus Prn Terbutaline in Mild-Moderate Asthma

Asthma

Italy
Tobira Therapeutics, Inc.

Completed

Efficacy, Safety, and Tolerability of Cenicriviroc (CVC) in Combination With Truvada or Sustiva Plus Truvada in HIV 1-infected, Antiretroviral Treatment-naïve, Adult Patients Infected With Only CCR5-tropic Virus

HIV-1 Infection

United States, Puerto Rico
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study Comparing Budesonide/Formoterol Easyhaler and Symbicort Turbuhaler Forte (ADECO)

Asthma

Germany
Hull University Teaching Hospitals NHS Trust

Completed

Effect on Adrenal Function of Budesonide Versus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Hospital General de Requena
Esteve

Completed

Efficacy of Budesonide-Formoterol in Bronchiectasis

Bronchiectasis

Spain
Boehringer Ingelheim

Completed

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Healthy
UNICANCER
AstraZeneca; Fondation ARC

Active, not recruiting

SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer (SAFIR02_Breast)

Metastatic Breast Cancer

France
Chiesi Farmaceutici S.p.A.

Completed

Efficacy and Safety Study of Beclometasone/Formoterol Single Inhaler in Patients With COPD

Chronic Obstructive Pulmonary Disease

France
Ain Shams University

Completed

Comparison Between Dexmeditomidine, Midazolam and Ketamine as a Sedative to Help Cannula Insertion in Pediatric Patient

Cannula Site Pain

Egypt
Athens General Children's Hospital "Pan. & Aglaia...

Completed

Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children

Effect of Anesthesia in Postoperative Pain | Effect of Anesthesia in Extubation Time | Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit | Effect of Anesthesia in Postoperative Adverse Events | Effect of Anesthesia in Discharge Time From the Hospital

Greece
West-Ward Pharmaceutical

Completed

Clinical Endpoint Bioequivalence Study of Fluticasone Propionate & Salmeterol Xinafoate (100μg/50μg)

Asthma

United States
AstraZeneca

Completed

A Clinical Study to Evaluate Symbicort Turbuhaler Used 'as Needed' in Adults and Adolescents With Asthma. (SYGMA1)

Asthma

Canada, Vietnam, Russian Federation, Korea, Republic of, Brazil, Peru, China, Ukraine, South Africa, Australia, Bulgaria, Hungary, Poland, Philippines, Romania, Mexico, Chile, United Kingdom
Menoufia University
Mamdoh Elsayed Lotfy; Osama Abdallah Elsharkawy; Basma Abdelhamid Fathy

Completed

Dexmedetomidine Versus Dexamethasone With Levobupivacaine in Interscalene Block (IBBB)

Postoperative Complications | Postoperative Analgesia

Egypt
GlaxoSmithKline

Completed

Outcomes From Initial Maintenance Therapy With Fluticasone Propionate 250/Salmeterol 50 (FSC) or Tiotropium in Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study to Compare Absorption of Budesonide/Formoterol Easyhaler and Symbicort Turbuhaler

Asthma

Finland
GlaxoSmithKline

Completed

Treatment Of Partial Reversible Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Netherlands
Boehringer Ingelheim

Completed

Ipratropium or Salbutamol Sulphate Alone or Combination Therapy Salbutamol and Ipratropium in Patients With COPD

Pulmonary Disease, Chronic Obstructive

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