Search clinical trials for: Sirukumab (IV infusion)

Total 7240 results

Janssen Research & Development, LLC
GlaxoSmithKline

Completed

Bioavailability and Pharmacokinetics Study of Sirukumab in Healthy Male Participants

Healthy

United States
Wockhardt

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of Intravenous WCK 771

Bioavailability

United States
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1, Randomized, Double-Blind, Placebo-Controlled Exploratory Study That Will Assess the Safety, Tolerability, Pharmacokinetics and Hemodynamic Response to a Single 30 Minute Intravenous Infusion of Vasomera™ (PB1046) in Adult Subjects With Stage 1 or 2 Essential Hypertension

Essential Hypertension

United States
Aro Biotherapeutics

Recruiting

Study to Assess the Safety, Tolerability, PK and PD of ABX1100

Healthy

Canada
Akeso

Recruiting

A Phase Ia/Ib Open Label，Clinical Study Evaluating the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK104 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors

China
AM-Pharma

Completed

Recombinant Human Alkaline Phosphatase in Healthy Japanese Subjects

Healthy

Japan
GlaxoSmithKline
PPD

Terminated

A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor (NEWBORN-1)

Obstetric Labour, Premature

United States, Italy, United Kingdom, Japan, Canada
University of Calgary

Not yet recruiting

NC Testing in LC & POTS

Postural Orthostatic Tachycardia Syndrome | Post Acute Sequelae of SARS CoV 2 Infection
University of Arkansas, Fayetteville

Completed

The Role of Hydration on Exercise Performance - ODIN (ODIN)

Dehydration

United States
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003 (SIRROUND-LTE)

Arthritis, Rheumatoid

United States, Poland, Ukraine, United Kingdom, Germany, Taiwan, Mexico, Portugal, Spain, Bulgaria, Malaysia, Romania, Serbia, South Africa, Korea, Republic of, Japan, Canada, Russian Federation, Chile, Puerto Rico, Austria, Argen... and more
Crucell Holland BV
National Institutes of Health (NIH); Division of Microbiology and Infectious...

Withdrawn

Assessment of Efficacy of CR8020 and CR6261, Monoclonal Antibodies, Against Influenza Infection

Influenza

United States, Australia, Canada, France, Germany, Spain, Belgium, Bulgaria, Netherlands, Brazil, South Africa, Sweden
Boehringer Ingelheim

Completed

Intravenous BI 6727 (Volasertib) in 2nd Line Treatment of Urothelial Cancer

Neoplasms

United States, Taiwan
AstraZeneca

Completed

A Study of MEDI7352 in Painful Osteoarthritis of the Knee

Chronic Pain

Germany, Sweden, United Kingdom
National University Hospital, Singapore

Unknown

The Role of Intravenous Albumin Replacement During Abdominal Paracentesis in Patients With Malignancy Related Ascites

Ascites | Hypotension

Singapore
The University of New South Wales

Completed

Faecal Microbiota Transplantation in Ulcerative Colitis (FOCUS)

Ulcerative Colitis | Inflammatory Bowel Disease

Australia
Prometheus Biosciences, Inc., a subsidiary of Merck...

Active, not recruiting

A Phase 2a Safety and Efficacy Open-Label Study of PRA023 in Subjects With Moderately to Severely Active Crohn's Disease (APOLLO-CD)

Crohn Disease

United States, Australia, Belgium, Canada, Czechia, France, Georgia, Poland
Cytokinetics

Completed

PK and Tolerability of IV and Oral CK-1827452 in Patients With Ischemic Cardiomyopathy and Angina

Myocardial Ischemia | Heart Failure | Angina Pectoris

Georgia, Russian Federation
Qpex Biopharma, Inc.
Biomedical Advanced Research and Development Authority

Completed

SAD/MAD Safety and PK Study of QPX9003 (Novel Polymyxin) in Normal Healthy Volunteers (QPX9003)

Bacterial Infections

United States
Takeda
Takeda Development Center Americas, Inc.

Active, not recruiting

Long-term Evaluation on Height and Weight in Patients With MPS II Who Started Treatment at < 6 Years of Age

Hunter Syndrome

United States, Germany, Malaysia, Philippines, Thailand, Dominican Republic, Serbia, Vietnam
Akeso

Recruiting

A Study of AK129 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors(Stage IA-IB)

China
Janssen Pharmaceutica N.V., Belgium

Completed

A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19

Critical Confirmed Coronavirus Disease (COVID)-19

United States
Alnylam Pharmaceuticals

Completed

The Study of ALN-TTR02 (Patisiran) for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02 (Patisiran)

TTR-mediated Amyloidosis

Portugal, Sweden, Brazil, United States, France, Spain, Germany
Rush University Medical Center

Completed

Comparison of the Leuven Protocol With the Glucommander for Postoperative Control of Blood Glucose With IV Insulin

Diabetes

United States
Janssen Research & Development, LLC

Completed

An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

Depressive Disorder, Major

United States, Poland, United Kingdom, Russian Federation, Canada
Bioblast Pharma Ltd.
Parexel

Completed

A Study to Establish Safety and Maximum Tolerated Dose of IV Trehalose in Healthy Subjects

Healthy Volunteer Subjects

United States
Genentech, Inc.

Completed

An Absolute Bioavailability Study in Healthy Participants Comparing Oral to Intravenous Administration of GDC-0973 (Cobimetinib)

Healthy Volunteers
Neuracle Science Co., LTD.

Completed

A FIH Study to Assess the Safety and Tolerability of NS Intravenous NS101 Infusion

Neurodegenerative Diseases

Canada
Polpharma Biologics S.A.

Completed

Efficacy and Safety of the Biosimilar Natalizumab PB006 in Comparison to Tysabri® (Antelope)

Relapsing-Remitting Multiple Sclerosis (RRMS)

Belarus, Ukraine, Georgia, Croatia, Moldova, Republic of, Poland, Serbia
AstraZeneca

Completed

A Study to Assess the Pharmacokinetics and Safety of Single Doses of Anifrolumab in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Safety

United States
Tetraphase Pharmaceuticals, Inc.
Department of Health and Human Services

Completed

Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women (BAL)

Normal Drug Tolerance

United States
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study Comparing Sirukumab (CNTO 136) Monotherapy With Adalimumab (HUMIRA®) Monotherapy in the Treatment of Active Rheumatoid Arthritis (SIRROUND-H)

Arthritis, Rheumatoid

United States, Poland, Ukraine, Germany, Spain, Colombia, Mexico, Bulgaria, Romania, Serbia, South Africa, Chile, Russian Federation, Hungary, Lithuania, Moldova, Republic of
Peking University
Merck Sharp & Dohme LLC; Cancer Institute and Hospital, Chinese Academy of... and other collaborators

Recruiting

Pembrolizumab and Chemotherapy Neoadjuvant/Adjuvant of NSCLC

Stage IIIA Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB Non-small Cell Lung Cancer | Stage IIIB(N2) Non-small Cell Lung Cancer

China
Uayporn Kaosombatwattana

Completed

Efficacy of Vonoprazan Versus Intravenous Proton Pump Inhibitors for Prevention of Rebleeding in High Risk Peptic Ulcers Bleeding After Successful Endoscopic Hemostasis

Peptic Ulcer With Haemorrhage

Thailand
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19 (COVID-19)

Covid 19

Mexico
Polpharma Biologics S.A.

Not yet recruiting

Efficacy, Safety and Immunogenicity of the Proposed Biosimilar Vedolizumab PB016 in Comparison With Entyvio® (UCESIVE)

Ulcerative Colitis
Yonsei University

Completed

The Effects of Dexmedetomidine and Tracheal Intubation on Heart Rate Variability and QTc Interval

Anesthesia, General

Korea, Republic of
The Emmes Company, LLC
Duke University; Stanford University

Completed

Dose-response Study of Sodium Nitroprusside in Children Requiring Controlled Hypotension in the Operating Room

Hypotension

United States
Eledon Pharmaceuticals

Withdrawn

Safety, Tolerability, and Efficacy of Immunomodulation With AT-1501 in Combination With Transplanted Islet Cells in Adults With Brittle T1D

Brittle Type 1 Diabetes Mellitus

United States
Pfizer

Completed

Glasdegib Absolute Bioavailability Study

Healthy Volunteer Study

United States
Radha Gopalan
American Regent, Inc.

Enrolling by invitation

Effects of IV Iron Replacement on Exercise Capacity in Individuals With Heart Failure

Heart Failure | Iron-deficiency

United States
Pfizer

Terminated

Study To Assess The Safety And Tolerability Of Increasing Single Doses Of ATR-107 (PF-05230900) In Healthy People

Healthy

United States
GammaDelta Therapeutics Limited

Terminated

Study of GDX012 in Patients With MRD Positive AML

Acute Myeloid Leukemia

United States
Yale University

Terminated

Pilot Study Of Anti-Programmed Death Ligand-1 (Anti-PD-L1, Atezolizumab) In Asymptomatic Myeloma

Asymptomatic Myeloma

United States
Beni-Suef University

Completed

Carbetocin Versus Oxytocin and Ergometrine for the Prevention of Postpartum Haemorrhage Following Caesarean Section

Anemia | Bleeding

Egypt
Takeda

Active, not recruiting

Specified Drug-Use Survey on Vedolizumab for IV Infusion 300 mg [Ulcerative Colitis]

Ulcerative Colitis

Japan
Boehringer Ingelheim

Completed

BI 655130 Long-term Treatment in Patients With moderate-to Severe Ulcerative Colitis

Colitis, Ulcerative

Spain, United Kingdom, United States, Belgium, Germany, Italy, Austria, Canada, Japan, Korea, Republic of, Russian Federation, Poland
Boehringer Ingelheim

Terminated

Volasertib + Decitabine in Patients With Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

United States
GlaxoSmithKline

Withdrawn

A Phase 2a Study to Evaluate the Effects of Sirukumab in Subjects With Severe Poorly Controlled Asthma

Asthma

United States, Spain
Neurocrine Biosciences
Takeda

Completed

A Study to Assess Absolute Bioavailability (ABA) of TAK-831 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]TAK-831 in Male Healthy Participants

Healthy Volunteers

United States
Bioblast Pharma Ltd.

Completed

Study To Assess Safety, Tolerability and Efficacy of Intravenous Cabaletta in Patients With Machado-Joseph Disease

Machado-Joseph Disease / Spinocerebellar Ataxia 3

Israel

Search clinical trials for: Sirukumab (IV infusion)

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