Search clinical trials for: Sitagliptin matched placebo

Total 54499 results

Merck Sharp & Dohme LLC

Completed

Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)

Type 2 Diabetes Mellitus
Michael A. Nauck

Completed

Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2D

Type 2 Diabetes

Germany
Takeda

Completed

Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Mexico
Fujian Akeylink Biotechnology Co., Ltd.

Recruiting

A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
Desentum Oy

Completed

Study to Evaluate Safety and Tolerability of sc Immunotherapy With DM-101 in Adults With Birch Pollen Allergy

Birch Pollen Allergy

Finland
Gilead Sciences

Terminated

Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis (PBC-Phase 2)

Primary Biliary Cholangitis

United States, Canada, Austria, United Kingdom
Albert Einstein College of Medicine
The Humsafar Trust

Active, not recruiting

CHALO! 2.0: A Mobile Technology Based Intervention to Accelerate HIV Testing and Linkage to Preventive Treatment.

Hiv

India
Kitov Pharma Ltd

Completed

Evaluation of Celecoxib Effects on Amlodipine in Subjects With Existing Hypertension Requiring Antihypertensives

Hypertension

United Kingdom
Eisai Inc.

Completed

A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006

Insomnia

United States
Gilead Sciences

Completed

Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Sclerosing Cholangitis Without Cirrhosis

Primary Sclerosing Cholangitis

United States, Canada, United Kingdom, Austria
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Israel, Ireland, United Kingdom
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Quetiapine Pharmacotherapy for Cannabis Dependence (QUEST)

Cannabis Dependence

United States
Boehringer Ingelheim

Completed

Linagliptin 2.5 mg Twice Daily Versus 5 mg Once Daily as add-on Therapy to Twice Daily Metformin in Type 2 Diabetes

Diabetes Mellitus, Type 2

Belgium, Canada, France, India, Italy, Korea, Republic of, Malaysia, Netherlands, Spain
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A

Malaria

Australia
University of Pisa
Merck Sharp & Dohme LLC

Completed

Metformin and Sitagliptin in Women With Previous Gestational Diabetes

Pre-diabetes

Italy
Biogen

Completed

Effect of Natalizumab on Infarct Volume in Acute Ischemic Stroke (ACTION)

Acute Ischemic Stroke

Spain, United States, Germany
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the Safety and Efficacy of the Addition of Omarigliptin (MK-3102) Compared With the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)

Type 2 Diabetes
University of Vermont

Completed

Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy

Impaired Glucose Tolerance | Pre-diabetes | Impaired Fasting Glucose

United States
Ohio State University Comprehensive Cancer Center
American Cancer Society, Inc.

Completed

Ohio Patient Navigator Research Program (OPNRP)

Cervical Cancer | Breast Cancer | Rectal Cancer | Colon Cancer | Abnormal Breast Cancer Screening Tests | Abnormal Cervical Cancer Screening Tests | Abnormal Colon Cancer Screening Tests

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Co-administration of Sitagliptin and Atorvastatin in Inadequately Controlled Type 2 Diabetes Mellitus (MK-0431E-211)

Type 2 Diabetes Mellitus
AstraZeneca
Eli Lilly and Company

Completed

A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)

Type 2 Diabetes Mellitus

United States, Mexico, India
Desentum Oy

Completed

Study to Evaluate Safety, Tolerability and Explorative Efficacy of DM-101PX in Birch Pollen Allergic Participants

Birch Pollen Allergy

Canada
Boehringer Ingelheim

Terminated

A Study to Test How Well Patients With Plaque Psoriasis Tolerate BI 730357 Over a Longer Period and How Effective it is

Psoriasis

United States, Canada, Germany
Gilead Sciences

Completed

Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator (TEMPO)

Ventricular Arrhythmia

Netherlands, Israel, United States, Denmark, Canada, Germany, Czechia, Hungary, Poland
Brii Biosciences Limited

Completed

A Study of BRII-297 in Healthy Adult Subjects

Postpartum Depression

Australia
Novartis Pharmaceuticals

Completed

Efficacy and Long-Term Safety of Vildagliptin as Add-on Therapy to Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Korea, Republic of, Latvia, Peru, Lithuania, Israel, Norway, Finland, Argentina, Austria, Belgium, Germany, Greece, Guatemala, Hungary, India, Italy, Mexico, Poland, Romania, Slovakia, Venezuela
Eli Lilly and Company

Completed

A Study of LY3325656 in Healthy Participants and Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2

Singapore
GlaxoSmithKline

Completed

A 2-Part Trial in Subjects With Type 2 Diabetes and in Healthy Subjects to Evaluate GSK1614235, a New Glucose Lowering Drug to Treat Type 2 Diabetes (SGA112534)

Diabetes Mellitus, Type 2

Germany, United States, France, United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study of an Investigational Drug Sitagliptin for Type 2 Diabetes Mellitus (0431-044)

Type 2 Diabetes Mellitus
Ono Pharmaceutical Co. Ltd

Completed

Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
University of California, San Diego
United States Department of Defense

Completed

Q10 for Gulf War Veterans (GULF)

Gulf War Illness

United States
University of California, San Diego
National Institute on Aging (NIA)

Completed

UCSD Q10 and Aging Study

Age Related Symptoms | Age Related Quality of Life Issues

United States
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ)

Malaria

United Kingdom
KU Leuven

Completed

The Effect of Omega-3 Supplementation on Muscle Functioning, Inflammation and Muscle Signaling

Aging

Belgium
Stryker Trauma GmbH

Recruiting

Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study (SiD)

Rotator Cuff Tears | Shoulder Deformity | Osteoarthritis Shoulder | Avascular Necrosis of the Head of Humerus | Rheumatoid Arthritis Shoulder | Fracture, Humeral | Traumatic Arthritis of Right Shoulder Region (Diagnosis)

United States
Lassen Therapeutics Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease

Eye Diseases | Endocrine System Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis

United States, United Kingdom, Spain
Istanbul University
Nestlé

Completed

Effect of Glutamine on Urinary Incontinence

Urinary Incontinence

Turkey
University of Southern California

Completed

Sitagliptin Effects on Arterial Vasculature and Inflammation in Obesity (SAVORO)

Inflammation | Atherosclerosis

United States
Merck Sharp & Dohme LLC

Completed

Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260)

Type 2 Diabetes Mellitus
Medical College of Wisconsin
Merck Sharp & Dohme LLC

Completed

Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy

Diabetes | Atherosclerosis

United States
GlaxoSmithKline

Completed

A Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 Administered With Metformin to Type 2 Diabetes Patients

Diabetes Mellitus, Type 2

United States
AstraZeneca
Eli Lilly and Company

Completed

Comparison of the Effect of Exenatide Versus Sitagliptin on 24-hour Average Glucose in Patients With Type 2 Diabetes on Metformin or a Thiazolidinedione

Type 2 Diabetes Mellitus

United States
Novartis Pharmaceuticals

Withdrawn

Dose-finding Study of LIK066 Compared With Placebo or Sitagliptin to Evaluate Change in HbA1c in Patients With Diabetes

Type 2 Diabetes Mellitus
Novartis Pharmaceuticals

Completed

Vildagliptin vs Sitagliptin add-on to Insulin - Impact on Glycemic Profile and Correlation of Hypoglycemic Episodes and Heart Function (CGM-VISIT)

Diabetes Mellitus Type 2

Germany
Merck Sharp & Dohme LLC

Completed

Study of the Bioequivalence of Two Tablet Forms of MK0431 (0431-027)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)

Type 2 Diabetes Mellitus
Eisai Inc.

Completed

Study of the Efficacy and Safety of Lemborexant in Subjects 55 Years and Older With Insomnia Disorder (SUNRISE 1) (SUNRISE 1)

Insomnia

United States, Spain, United Kingdom, Italy, Germany, France, Canada
Gilead Sciences
Galapagos NV

Completed

Study to Evaluate the Efficacy and Safety of Filgotinib in the Treatment of Perianal Fistulizing Crohn's Disease (Divergence2)

Fistulizing Crohn's Disease

United States, Italy, Belgium, Austria, Canada, Hungary, United Kingdom, Germany, France
Gilead Sciences
Galapagos NV

Terminated

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Psoriatic Arthritis Who Have an Inadequate Response or Are Intolerant to Biologic DMARD Therapy (PENGUIN 2)

Psoriatic Arthritis

Korea, Republic of, United States, Australia, Belgium, Canada, Czechia, Hungary, Japan, Poland, Spain, Taiwan
Gilead Sciences
Galapagos NV

Completed

Study to Evaluate the Efficacy and Safety of Filgotinib in the Treatment of Small Bowel Crohn's Disease (SBCD) (DIVERGENCE 1)

Small Bowel Crohn's Disease

United States, Belgium, United Kingdom, Germany, Spain, Czechia, Canada, Austria, France, Hungary, Italy, Ukraine

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