Search clinical trials for: Sodium Chloride Symporter Inhibitors

Total 5249 results

University of Edinburgh
Kidney Cancer UK

Terminated

Heme Arginate in Transplantation Study (HOT2)

Renal Transplant Rejection | Renal Transplant Failure

United Kingdom
Umeå University

Terminated

Contrast Enhanced Sonothrombolysis and Sonolysis in Stroke - a Swedish Study (CE-5S) (CE-5S)

Ischemic Stroke

Sweden
Novo Nordisk A/S

Completed

A Trial Investigating the Effect of Oral Semaglutide on the Pharmacokinetics of Furosemide and Rosuvastatin in Healthy Subjects

Healthy | Diabetes

United Kingdom
Rabin Medical Center

Completed

Effect of Acetazolamide and Furosemide on Obesity-induced Glomerular Hyperfiltration

Obesity-induced Hyperfiltration

Israel
Shanghai Changzheng Hospital
The First Affiliated Hospital of Anhui Medical University; Ruijin Hospital; First... and other collaborators

Unknown

Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With Hypertension (BEAHIT)

Chronic Kidney Disease

China
St George's, University of London

Terminated

Extracellular Fluid in Resistant Hypertension

Hypertension

United Kingdom
University Hospital Hradec Kralove
Masaryk University

Recruiting

The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory Diseases (INFURO)

Dyspnea

Czechia
National Cardiovascular Center Harapan Kita Hospital...

Completed

Low Dose Continuous Furosemide Effect on Cardiac Surgery Patients With Kidney Dysfunction

Chronic Kidney Disease | Cardiac Disease

Indonesia
Boryung Pharmaceutical Co., Ltd

Completed

A Clinical Trial to Evaluate Drug-drug Interactions and Safety Between "BR1015-1" and "BR1015-2" in Healthy Volunteers

Hypertension

Korea, Republic of
SQ Innovation, Inc.
Accel Clinical Services

Completed

Crossover Study to Compare the Pharmacokinetics and Bioavailability of a Novel Furosemide Regimen Administered Subcutaneously vs. the Same Dose Administered Intravenously in Subjects With Chronic Heart Failure

Heart Failure

United States
University Hospital, Geneva

Completed

Resistant Arterial Hypertension Cohort Study (RAHyCo)

Hypertension | Essential Hypertension | Resistant Hypertension

Switzerland
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Irbesartan HCTZ 300/25 mg Tablets Under Fasted Conditions

Hypertension

United States
Boehringer Ingelheim

Completed

Bioequivalence of Telmisartan/ HCTZ Fixed Dose Combination Compared With Its Monocomponents in Healthy Male Volunteers II

Healthy
Boehringer Ingelheim

Completed

TELSYS - TELmisartan Effectiveness in Isolated SYStolic Hypertension Versus Systolic/Diastolic Hypertension Patients Aged 55 or Older (TELSYS)

Hypertension
Boehringer Ingelheim

Completed

An Observational Study to Investigate the Efficacy, Safety, Tolerability and the Effect on Quality of Life of Telmisartan (Micardis) and Telmisartan With HCTZ (Micardis Plus) in Patients With Hypertension

Hypertension

Korea, Republic of
Novartis

Completed

A Study Comparing Valsartan With And Without Hydrochlorothiazide In Patients With Hypertension

Hypertension

United States
Sodertalje Hospital

Completed

Kinetic Method to Detect Dehydration

Dehydration

Sweden
Brigham and Women's Hospital
National Institutes of Health (NIH)

Completed

Aldosterone and Vascular Disease in Diabetes Mellitus

Diabetes Mellitus | Albuminuria | Endothelial Dysfunction

United States
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide

Drug Interaction Potentiation

Canada
Hospices Civils de Lyon

Completed

IDEAL Study: Identification of the Determinants of the Efficacy of Arterial Blood Pressure Lowering Drugs

Hypertension

France
Hospital de Clinicas de Porto Alegre
Instituto de Cardiologia do Rio Grande do Sul

Unknown

Efficacy of Chlorthalidone and Hydrochlorothiazide Combined With Amiloride on Blood Pressure in Primary Hypertension.

Hypertension

Brazil
Hospital General de Niños Pedro de Elizalde

Completed

Efficacy of Nebulized Hypertonic Saline in the Treatment of Acute Bronchiolitis (Hypertonic)

Bronchiolitis

Argentina
Southeast University, China

Unknown

Low-chlorine Vs High-chlorine Crystalloids in Septic Shock Adults

Septic Shock
Joseph Pilewski
Cystic Fibrosis Foundation

Completed

Effects of Inhaled Bicarbonate on Airway pH in Cystic Fibrosis

Cystic Fibrosis

United States
University of Calgary

Recruiting

Hydroxychloroquine and Indapamide in SPMS

Multiple Sclerosis, Secondary Progressive

Canada
Maruho Co., Ltd.

Unknown

Topical Ionic Contra-Viral Therapy in Actinic Keratosis

Actinic Keratosis

Netherlands
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Quinapril Hydrochloride 20 mg and Hydrochlorothiazide 25 mg Tablets Under Fed Conditions

Healthy

India
Hospital de Clinicas de Porto Alegre

Completed

Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea (DESALT)

Obstructive Sleep Apnea

Brazil
Indiana Institute for Medical Research

Recruiting

Spironolactone in CKD Enabled by Chlorthalidone: PILOT (SPICE PILOT)

Renal Insufficiency | Chronic Hypertension

United States
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Two Formulations of Torasemide Tablet 10 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
University of Maryland, Baltimore
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Salt Loading and Thiazide Intervention Study (SALTI)

Hypertension

United States
University of California, San Diego

Completed

Treatment of OSA Associated Hypertension With Alpha 2 Agonist or Diuretic (guanhctz)

Obstructive Sleep Apnea
Johns Hopkins University

Completed

Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction (ROPA-DOP)

Heart Failure, Diastolic

United States
Novartis

Completed

A 16 Week Study to Evaluate the Effect on Insulin Sensitivity of Valsartan (320 mg) and Hydrochlorothiazide (25 mg) Combined and Alone, in Patients With Metabolic Syndrome

METABOLIC SYNDROME | HYPERTENSION | PRE-HYPERTENSION

United States
HanAll BioPharma Co., Ltd.

Completed

Pharmacokinetic Interactions and Safety Study of Telmisartan and Chlorthalidone

Hypertension

Korea, Republic of
Novartis

Completed

Valsartan/Hydrochlorothiazide Combination in the Treatment of Severe Hypertension

Hypertension

United States
Tottori University Hospital

Completed

Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure

Chronic Stable Heart Failure
Bayer

Completed

PK in Pts With HRPC & Skeletal Metastes

Prostatic Neoplasms

United Kingdom
Ottawa Hospital Research Institute

Completed

Crystalloid FLUID Choices for Resuscitation of Hospitalized Patients (FLUID)

Fluid Therapy

Canada
Invivyd, Inc.
Novotech (Australia) Pty Limited

Active, not recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of the Monoclonal Antibody VYD222 in Healthy Adult Participants

COVID-19

Australia
MassBiologics
Celerion

Completed

First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People

Lyme Disease

United States
Guangdong Women and Children Hospital

Unknown

The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells

Safety Issues | Effect of Drugs
Paddock Laboratories, Inc.

Completed

A Study to Compare the Relative Bioavailability of Moexipril HCl/Hydrochlorothiazide in Healthy Adult Volunteers Under Fasting Conditions

Healthy

United States
Teva Pharmaceuticals USA

Completed

Moexipril HCL/Hydrochlorothiazide 15/25 mg Tablets Under Fasting Conditions

Healthy

United States
Teva Pharmaceuticals USA

Completed

Moexipril HCl/Hydrochlorothiazide 15/25 mg Tablets Under Non-Fasting Conditions

Healthy

United States
Lawson Health Research Institute

Recruiting

Flexible vs. Fixed Diuretic Regimen in the Management of Chronic Heart Failure: A Pilot Study

Heart Diseases | Heart Failure

Canada
Roxane Laboratories

Completed

Crossover Bioequivalence Study of Irbesartan Hydrochlorothiazide 300/25 mg Tablets Under Fed Conditions

Hypertension

United States
Shanghai Chest Hospital

Completed

The Safety and Efficacy of Tolvaptan for Patients With Tricuspid Regurgitation and Right Heart Failure After Left Heart Valves Replacement

Right Heart Failure | Tricuspid Regurgitation

China
Boehringer Ingelheim

Completed

Evaluation of Efficacy and Tolerability of Micardis® / MicardisPlus® Under Usual Daily-practice Prescribing in Patients With Hypertension

Hypertension
Boehringer Ingelheim

Completed

Relative Oral Bioavailability of Telmisartan / Hydrochlorothiazide (HCTZ) Fixed Dose Combination (FDC) Compared With Its Monocomponents in Healthy Subjects

Healthy

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