Search clinical trials for: Somatropin and pegvisomant

Total 270691 results

Herlev Hospital

Unknown

The Relationship Between the Growth Hormone (GH)- Insulin Like Growth Factor I (IGF-I) System and the Inflammatory System in Healthy Normal Persons

Interaction Between the GH/IGF-I System and the Immune-system

Denmark
University of Aarhus
Pfizer; Aarhus University Hospital

Completed

Growth Hormone During Fasting.Signaltransduktion in Muscle and Adipose Tissue and Changes in Intrahepatic Lipid Content

Fatty Liver | Metabolism

Denmark
OPKO Health, Inc.

Active, not recruiting

Safety and Efficacy Phase 3 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Pediatric Growth Hormone Deficiency

Israel, United States, India, Korea, Republic of, Australia, Taiwan, Spain, Argentina, Belarus, Bulgaria, Canada, Colombia, Georgia, Greece, Mexico, New Zealand, Poland, Russian Federation, Ukraine, United Kingdom
Pfizer

Completed

Long Term Study With B2036-PEG

Acromegaly

Japan
Unity Health Toronto

Completed

Strict IGF-1 Control in Acromegaly (I-Con)

Acromegaly

Canada
Cedars-Sinai Medical Center

Completed

Tissue Biomarker for Pegvisomant Action

Acromegaly

United States
Columbia University
Pfizer

Completed

Bone MicroArchitecture in Acromegaly

Acromegaly | Osteoporosis Risk

United States
Pfizer

Completed

A Relative Bioavailability Study To Evaluate Safety, Tolerability And Pharmacokinetic Comparability Of Pegvisomant 1 X 30 Mg Vs 2 X 15 Mg Subcutaneously Administered In Healthy Subjects

Healthy Volunteers

Belgium
Pfizer

Completed

Safety, Tolerability and Relative Bioavailability of Pegvisomant in Healthy Subjects

Bioavailability

Singapore
Eunice Kennedy Shriver National Institute of Child...

Recruiting

Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess

Pituitary Disease

United States
National Institute of Dental and Craniofacial Research...

Completed

A Study of the Effects of Pegvisomant on Growth Hormone Excess in McCune-Albright Syndrome

McCune Albright Syndrome | Polyostotic Fibrous Dysplasia

United States
University of Wuerzburg
Pfizer

Unknown

Changes of Left Ventricular Mass and Cardiac Function in Patients With Active Acromegaly During Treatment With the Growth Hormone Receptor Antagonist Pegvisomant

Heart Failure | Acromegaly | Hypertrophy, Left Ventricular

Germany
Pfizer

Completed

Pegvisomant And Sandostatin LAR Combination Study

Acromegaly

Canada, United States, Germany, Italy, United Kingdom, Norway, Australia, Spain, Brazil, Mexico, France, Netherlands
Xiamen Amoytop Biotech Co., Ltd.
Peking Union Medical College Hospital

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Pegylated-Somatropin in Healthy Volunteers (Somatropin)

Healthy

China
National Institute of Diabetes and Digestive and...

Recruiting

Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

Insulin Receptor Mutation | Partial Lipodystrophy

United States
Erasmus Medical Center

Completed

Change in Quality of Life After Addition of Weekly 40 mg Pegvisomant/Placebo in Controlled Acromegalic Patients (mec-2005-290)

Quality of Life | Acromegaly
Pfizer

Active, not recruiting

Study of the Efficacy and Safety of Somatropin in Japanese Participants With PWS

Prader-Willi Syndrome

Japan
University of California, San Francisco
San Francisco General Hospital

Completed

Role of Growth Hormone Antagonism in Modulating Insulin Sensitivity in Subjects With Pre-diabetes (PEGIR)

Diabetes | Metabolic Syndrome | Insulin Resistance

United States
Pfizer

Completed

Long Term Use of Somavert (Pegvisomant) For A Regulatory Post Marketing Commitment Plan

Acromegaly
Pfizer

Terminated

Figitumumab Combined With Pegvisomant For Advanced Solid Tumors

Sarcoma | Breast Neoplasms | Lung Neoplasms | Prostatic Neoplasms | Colorectal Neoplasms

United States, Finland, Canada, Germany
University of Aarhus

Completed

Substrate Metabolism, Growth Hormone Signaling, and Insulin Sensitivity During Fasting

Healthy

Denmark
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Active, not recruiting

A Study Extension Period of PEG-somatropin (Pegylated-somatropin) in the Treatment of Children With Idiopathic Short Stature

Dwarfism

China
Pfizer

Completed

Evolution Of Growth Rate In Children With Growth Retardation Due to Glucocorticosteroid Therapy And Treated By Genotonorm

Growth Hormone Deficiency

France
Novo Nordisk A/S

Completed

Genetic Testing of Noonan Subjects Previously Treated With Norditropin®. An Extension to Trial GHNOO-1658

Noonan Syndrome | Genetic Disorder

Sweden
Novo Nordisk A/S

Completed

Post Marketing Surveillance on Long-term Use With Norditropin® (Short Stature Due to Noonan Syndrome)

Noonan Syndrome | Genetic Disorder

Japan
LG Chem

Completed

6x3 Crossover, Bioavailability, Safety and Tolerability Among Different Eutropin Formulations in Healthy Volunteers

Bioavailability, Safety and Tolerability Among Different Eutropin Formulations in Healthy Volunteers

Korea, Republic of
Novo Nordisk A/S

Completed

Observational Study of the Safety and Efficacy of Norditropin® in Patients With SGA (Small for Gestational Age) Short Stature That Are Still Growing

Foetal Growth Problem | Small for Gestational Age

Japan
Novo Nordisk A/S

Completed

A Survey Collecting Data on Adult Height in Patients With Achondroplasia Treated With Somatropin

Achondroplasia | Genetic Disorder

Japan
Novo Nordisk A/S

Completed

Somatropin Effect on Linear Growth and Final Height in Subjects With Noonan Syndrome

Noonan Syndrome | Genetic Disorder

Sweden
Novo Nordisk A/S

Withdrawn

Bioequivalence of Two Products (Norditropin® Versus Nutropin AQ®) in Healthy Adult Volunteers

Healthy | Growth Disorder
Genentech, Inc.

Terminated

A Study to Evaluate Growth in Participants Treated With Somatropin (Nutropin) Using NuSpin Device

Growth Hormone Deficiency

United States
GeneScience Pharmaceuticals Co., Ltd.
Huazhong University of Science and Technology

Completed

Crossover Study to Assess the Safety and Pharmacokinetic of Pegylated Somatropin(PEG Somatropin) in GHD Children (Phase 1)

Growth Hormone Deficiency
Novo Nordisk A/S

Completed

Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to Noonan Syndrome

Noonan Syndrome | Genetic Disorder

Japan
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Adults (NordiWIN)

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Germany
Novo Nordisk A/S

Completed

French National Registry of Children Born Small for Gestational Age Treated With Somatropin

Small for Gestational Age | Growth Disorder

France
Novo Nordisk A/S

Completed

Observational Prospective Study on Patients Treated With Norditropin®

Chronic Kidney Disease | Turner Syndrome | Noonan Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age

Israel, Saudi Arabia, Spain, Argentina, Russian Federation, Germany, Netherlands, Italy, Belgium, United Kingdom, Slovenia, Ireland, Sweden, Denmark, Hungary, Finland, Norway, France, Czechia, Lithuania, Luxembourg, Serbia, Switzerland
Novo Nordisk A/S

Completed

Growth Response in Girls With Turner Syndrome

Turner Syndrome | Genetic Disorder

France
Novo Nordisk A/S

Completed

Use of Somatropin in Turner Syndrome

Turner Syndrome | Genetic Disorder

United Kingdom
Novo Nordisk A/S

Completed

Special Survey for Long Term Application

Achondroplasia | Genetic Disorder

Japan
Novo Nordisk A/S

Completed

Bioequivalence of Two Somatropin Products (Norditropin® Versus Genotropin®) in Healthy Adult Volunteers

Healthy | Prader-Willi Syndrome | Genetic Disorder | Growth Disorder | Idiopathic Short Stature

United States
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Children (GrowthWIN II)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age | Growth Disorder | Idiopathic Short Stature

Germany
Pfizer

Completed

Growth Retardation In Children With Special Pathological Conditions Or Disease

Endocrine System Diseases

France
Azidus Brasil

Unknown

Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Somatropin Produced by Laboratory Blausiegel Indústria e Comércio Ltda., Compared to Saizen® From Laboratory Merck Serono S.A.

Growth Retardation | GH Deficiency (GHD)

Brazil
Pfizer

Completed

Special Investigation Of Genotropin Long Follow-Up For Patients With A Small For Gestational Age "Scoped for Japanese"

Small for Gestational Age (SGA)
Novo Nordisk A/S

Terminated

The Effect of Somatropin Treatment in Adult Patients on Chronic Dialysis (OPPORTUNITY)

Chronic Kidney Disease | End-Stage Renal Disease

France, United States, Spain, United Kingdom, Canada, Denmark, Germany, Sweden, Argentina, India, Israel, Russian Federation, Hungary, Turkey, Italy, Poland, South Africa, China, Brazil, Portugal, Puerto Rico
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Completed

A Study of Recombinant Human Growth Hormone Injection（JINTOPIN AQ）for Short Children With Small for SGA

Small for Gestational Age Infant

China
Ascendis Pharma Endocrinology Division A/S

Active, not recruiting

A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome

Turner Syndrome

United States
Novo Nordisk A/S

Completed

A Single Dose Trial in Healthy Caucasians and Japanese Subjects Investigating the Pharmacokinetics of Somatropin

Healthy | Growth Hormone Disorder | Adult Growth Hormone Deficiency

United States
GeneScience Pharmaceuticals Co., Ltd.
Children's Hospital of Fudan University; The First Hospital of Jilin University and other collaborators

Unknown

Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat SGA Children With Short Stature

Small for Gestational Age Infant

China
HanAll BioPharma Co., Ltd.

Completed

Safety, Pharmacokinetics and Pharmacodynamics Study of HL-032 in Healthy Male Volunteers (HL-032)

Growth Hormone Deficiency

Korea, Republic of

Search clinical trials for: Somatropin and pegvisomant

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