Search clinical trials for: sorafenib tosylate

Total 2154 results

The University of Texas Health Science Center at...

Recruiting

Sorafenib Induced Autophagy Using Hydroxychloroquine in Hepatocellular Cancer

Hepatocellular Cancer

United States
National Cancer Institute (NCI)

Completed

Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas

Plexiform Neurofibroma | Neurofibromatosis Type I

United States
Sponsor GmbH
iOMEDICO AG

Completed

Sequential Study to Treat Renal Cell Carcinoma

Renal Cell Carcinoma

Germany
University of Cologne

Completed

SORAVE - Sorafenib and Everolimus in Solid Tumors (SORAVE)

Non-Small Cell Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

Germany
Sun Yat-sen University

Completed

Study of Combination of Sorafenib With Cisplatin and 5-fluorouracil as First-line Treatment of Recurrence After Radiotherapy Patients Who Failed With Radiotherapy in Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)

Nasopharyngeal Neoplasms

China
Duke University
Bayer

Terminated

Pilot Trial of "Chemo-Switch" Regimen to Treat Advanced Melanoma

Melanoma
Chinese Anti-Cancer Association

Completed

Urea Cream Treatment Sorafenib-Associated HSFR in HCC

Hepatocellular Carcinoma

China
Tongji Hospital

Completed

Study on the Safety and Effectiveness of Remimazolam Tosilate for Injection for Short-term Elective Surgery in Adults

Hypotension During Surgery

China
Melius Pharma AB

Not yet recruiting

Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF) (COSMIC-IPF)

Cough | Idiopathic Pulmonary Fibrosis

India
Wuhan Union Hospital, China
Yichang Humanwell Pharmaceutical Co., Ltd., China

Recruiting

PK/PD Properties and Safety of Remazolam Besylate for Injection in ICU Patients With Impaired Renal Function

Mechanically Ventilated Patients

China
Eisai Inc.

Completed

Compassionate Use of Eribulin for the Treatment of Advanced Breast Cancer Refractory to All Other Marketed Therapies

Breast Cancer

United States
Eisai Co., Ltd.

Completed

Study of E7389 for Advanced or Metastatic Breast Cancer

Breast Cancer

Japan
Sun Yat-sen University

Active, not recruiting

HAIC Plus Sorafenib Versus TACE Plus Sorafenibfor Advanced HCC

Hepatocellular Carcinoma

China
University Hospital Muenster
Eli Lilly and Company; Bayer

Terminated

Study in Patients With Advanced Non-Small Cell Lung Cancer Treated With Pemetrexed and Carboplatin Plus or Minus Sorafenib (PECASO)

Carcinoma, Non-Small-Cell Lung

Germany
Yale University

Withdrawn

Randomized Phase II Trial of Chemoembolization and Sorafenib

Hepatocellular Carcinoma

United States
Zhongda Hospital

Recruiting

HAIC Combined With Donafenib and Sintilimab for Unresectable ICC

Cholangiocarcinoma

China
Calgent Biotechnology Co., Ltd

Completed

Safety, Tolerability, and Pharmacokinetics of CAL056 Mesylate in Patients With Resistant or Refractory Solid Tumors

Resistant or Refractory Solid Tumors

United States, Taiwan
Eisai Korea Inc.

Completed

Eribulin Mesylate Phase IV Clinical Trial in Korean Patients With Metastatic or Locally Advanced Breast Cancer (ESKIMO)

Breast Cancer | Breast Neoplasms

Korea, Republic of
Eisai Inc.

Approved for marketing

An Open-Label, Multi-Center, Expanded Access Program With Eribulin for the Treatment of Advanced Breast Cancer Refractory

Metastatic Breast Cancer

Canada, Belgium, France
Merz Pharmaceuticals GmbH

Terminated

Open-Label, Long-Term Treatment Study, to Assess the Long-Term Safety and Tolerability and Efficacy of Neramexane in Patients With Subjective Tinnitus (OLLTT)

Subjective Tinnitus

United States, United Kingdom, Poland, Austria, Belgium, Brazil, Czech Republic, France, Germany, Mexico, Netherlands, Portugal, South Africa, Spain
Pathway Therapeutics, Inc.

Completed

Study of PWT33597 Mesylate in Subjects With Advanced Malignancies

Malignancies

United States
Merz Pharmaceuticals GmbH

Terminated

Open-lable Extension Study on Safety and Efficacy of Neramexane to Treat Congenital and Acquired Nystagmus

Multiple Sclerosis | Nystagmus, Congenital | Nystagmus, Acquired

United Kingdom
Merz Pharmaceuticals GmbH

Completed

Investigate the Effect of Neramexane Mesylate IR Tablet on Driving Fitness and Capability to Operate Machines in Healthy Volunteers

Healthy

Germany
Italian Trial in Medical Oncology

Completed

Study of Sorafenib and Infusional 5-Fluorouracil in Advanced Hepatocellular Carcinoma (HCC) (P2)

Hepatocellular Carcinoma

Italy
Nanjing First Hospital, Nanjing Medical University

Enrolling by invitation

Mid-and Long-term Efficacy of Ergot Alkaloids in the Treatment of Salivation in Patients With Parkinson's Disease.

Main Heading (Descriptor) Terms

China
Eisai Limited

Completed

QT Interval Prolongation Study of Eribulin Mesylate (E7389) in Patients With Advanced Solid Tumors

Advanced Solid Tumor

France
St. Jude Children's Research Hospital
Ohio State University; Arog Pharmaceuticals, Inc.

Completed

Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

Acute Myeloid Leukemia

United States
First Affiliated Hospital of Zhejiang University

Unknown

Treatment of Non-small Cell Lung Cancer With PD-1 Monoclonal Antibody Combined With Donafenib Toluene Sulfonate

Non-small Cell Lung Cancer

China
The First Affiliated Hospital of Soochow University

Recruiting

Individualized Induction Therapy for Non-elderly Acute Myeloid Leukemia Patients With Adverse Risk Features

Acute Myeloid Leukemia, Adult

China
Thomas Jefferson University

Completed

A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective

Advanced Liver Cancer | Metastatic Hepatocellular Carcinoma

United States
Bayer
Amgen

Completed

A Treatment Combination for Patients With Unresectable Stage III or Stage IV Melanoma

Melanoma

United States, Canada, Germany, France, United Kingdom, Australia, Netherlands
Combined Military Hospital, Pakistan
Bayer

Unknown

Study of Sorafenib and Gemcitabine in Advanced Hepatocellular Carcinoma (HCC) (HCC)

Hepatocellular Carcinoma

Pakistan
Pfizer

Completed

Study Of The Impact Of Inlyta In 2nd Line On The Treatment Outcomes Of mRCC Patients Treated With Sutent In 1st Line In The Real Life Setting (ADONIS)

Metastatic Renal Cell Carcinoma (mRCC)

Spain, Italy, Belgium, France, United Kingdom, Austria, Greece, Netherlands
Sun Yat-sen University

Completed

TACE Plus Sorafenib Versus TACE Alone for Recurrent Intermediate Hepatocellular Carcinoma (TREAT)

Hepatocellular Carcinoma | Sorafenib | Transarterial Chemoembolization

China
University of California, San Francisco
Pfizer; Robert H. Lurie Cancer Center

Completed

Phase II Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

United States
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Terminated

Third Line TKI After 2 TKIs in Patients With mRCC (Tokio Study) (TOKIO)

Renal Cancer Cell

Italy
Philipps University Marburg Medical Center

Withdrawn

Temsirolimus + Sorafenib in Advanced Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma

Germany
Memorial Sloan Kettering Cancer Center
Bayer

Terminated

Gemcitabine and Split-dose Cisplatin (GC) Plus Sorafenib in Chemotherapy-naïve Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Bladder Cancer | URINARY BLADDER

United States
Bayer

Terminated

A Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel Plus or Minus Sorafenib (BAY43-9006) in Chemonaive Patients With Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

China, Taiwan, Singapore, Thailand, Korea, Republic of, India
Fudan University

Terminated

Sorafenib Combined With Aspirin to Prevent the Recurrence in High-risk Patients With Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
GlaxoSmithKline

Completed

Incidence, Prevalence, and Symptom Burden Associated With Advanced Renal Cell Carcinoma in Commercially Insured Population (Pharmetrics)

Carcinoma, Renal Cell
Medical University of Vienna
Stanley Medical Research Institute

Completed

Indicated Prevention With Omega-3 Fatty Acids in Adolescents With 'At-Risk-Mental-State' for Psychosis

Schizophrenia | Prodrome

Austria
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Eribulin Mesylate Combined With Lobaplatin in the Treatment of Recurrent or Metastatic Triple-negative Breast Cancer

Triple Negative Breast Cancer

China
Sunshine Lake Pharma Co., Ltd.

Recruiting

A Clinical Trial to Evaluate Clifutinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia(AML)

Acute Myeloid Leukemia

China
Eisai Inc.

Completed

A Study to Evaluate Safety, Tolerability and Efficacy of Eribulin Mesylate in Treating Adult Females With Locally Advanced or Metastatic Breast Cancer

Breast Neoplasms

India
Eisai Inc.
Children's Oncology Group

Completed

This is a Phase 1 Study of Eribulin Mesylate in Pediatric Participants With Recurrent or Refractory Solid Tumors (Excluding [Central Nervous System] CNS), Including Lymphomas (BOLD 113)

Solid Tumors | Pediatrics

United States
Chang Gung Memorial Hospital
Eisai Co., Ltd.; Kaohsiung Breast Cancer Prevention and Education Society (KBCPES)

Unknown

Halaven Patient Registry (Metastatic Breast Cancer, MBC)

Advanced Breast Cancer | Metastatic Breast Cancer

Taiwan
Eisai Co., Ltd.

Completed

An Open-label, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Previously Treated Subjects With Advanced or Metastatic Soft Tissue Sarcoma (Study E7389-J081-217)

Soft Tissue Sarcoma

Japan
Merz Pharmaceuticals GmbH

Completed

Efficacy, Safety and Tolerability of Neramexane in Patients With Subjective Tinnitus (EASE)

Subjective Tinnitus

Germany, Portugal, Spain, United Kingdom, Austria
Eisai Inc.

Completed

Study Of Eribulin (E7389) In Patients With Advanced Solid Tumors And Normal Or Reduced Hepatic Function As Per Child-Pugh System

Cancer

Netherlands

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