Search clinical trials for: Structured discontinuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER)

Total 32 results

Member Companies of the Opioid PMR Consortium

Terminated

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse

United States
MedVadis Research Corporation

Completed

Effect of Extended-release Oxymorphone Taken With or Without Food on Cognitive Functioning

Chronic Pain

United States
Endo Pharmaceuticals

Terminated

Open-Label Safety and Tolerability of Oxymorphone IR and ER in Opioid Tolerant Pediatric Subjects

Chronic Pain

United States
Endo Pharmaceuticals
Kendle Early Stage - Toronto

Completed

Study to Compare Oxymorphone Extended-Release (Opana ER) Versus Oxycodone Controlled-Release (Oxycontin)

Healthy

Canada
Stanford University

Terminated

Inflammatory Responses to Acute and Chronic Opioid Exposure in Humans

Inflammation

United States
Endo Pharmaceuticals

Completed

Open Label Assessment of Long-Term Safety and Utility

Pain
Icahn School of Medicine at Mount Sinai
Endo Pharmaceuticals

Unknown

A Pilot Study of Ultra Rapid Opioid Rotation and Titration of Oxymorphone

Neuropathic Pain | Non-cancer Pain | Chronic Nociceptive Pain

United States
Endo Pharmaceuticals

Completed

Open-Label Extension to Evaluate the Long-Term Safety, Tolerability and Analgesic Efficacy

Lower Back Pain | Cancers, Pain

United States
Endo Pharmaceuticals

Suspended

Safety, Tolerability, Effectiveness, and Pharmacokinetic Data in Opioid-experienced Children

Chronic Pain | Postsurgical Pain

United States
Ajay Wasan, MD, Msc
Collegium Pharmaceutical, Inc.

Terminated

Use of Xtampza ER to Overcome Difficulties in Swallowing Opioid Pills

Chronic Pain | Opioid Use | Deglutition

United States
Janssen Research & Development, LLC

Completed

A Safety and Efficacy Study of JNS024 Extended Release (ER) in Japanese and Korean Patients With Chronic Malignant Tumor-Related Cancer Pain

Pain

Japan, Korea, Republic of
Pfizer

Completed

A Study of ARRY-371797 in Patients With Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Pfizer

Completed

Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant Pain

Pain

United States
Purdue Pharma LP

Completed

Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Emory University
Orthopedic Research and Education Foundation

Completed

Are Opioids Needed After ACL Reconstruction

Anterior Cruciate Ligament Rupture

United States
University of Alabama at Birmingham

Completed

Pilot Trial of Microsphere Oxycodone (Xtampza ER) for Pain Management in Patients Receiving Radiotherapy for Locally Advanced Head and Neck Cancer (RAD 1702)

Locally Advanced Head and Neck Cancer

United States
Daiichi Sankyo, Inc.

Completed

Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB) (BEAD-MB)

Baseline Epidemiologic Assessment

United States
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Low Back Pain

Low Back Pain
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Compare the Frequency of Constipation Symptoms With Tapentadol Immediate Release (IR) Treatment Versus Oxycodone IR Treatment in Patients With End-stage Joint Disease

Arthritis | Joint Diseases | Osteoarthritis
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain

Pain | Lower Back Pain | Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Canada
Janssen Pharmaceutical K.K.

Completed

A Safety and Efficacy Study of Oral Tapentadol Extended-Release in Japanese Participants

Neoplasms

Japan
Medlab Clinical
George Clinical Pty Ltd; WriteSource Medical Pty Ltd

Not yet recruiting

NanaBis™ an Oro-buccal Administered delta9-Tetrahydrocannabinol (d9-THC) & Cannabidiol (CBD) Medicine for the Management of Bone Pain From Metastatic Cancers

Cancer Related Pain
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Terminated

A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)

Diabetic Neuropathy, Painful | Diabetic Polyneuropathy

United States
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

Pain | Knee Osteoarthritis

Austria, Croatia, Germany, Hungary, Italy, Latvia, Netherlands, Poland, Portugal, Romania, Slovakia, Spain, United Kingdom
University of Utah

Completed

A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery

Opioid Use

United States
University Hospitals Bristol and Weston NHS Foundation...

Completed

Oxycodone or Standard Pain Therapy in Treating Patients With Cancer Pain

Pain | Unspecified Adult Solid Tumor, Protocol Specific
Foisor Orthopedics Clinical Hospital

Completed

Perineural Low-dose Dexamethasone Added to Infraclavicular Block Anesthesia

Postoperative Pain

Romania
University of Utah

Active, not recruiting

Role of Multimodal Analgesia in Decreasing Perioperative Pain in Tibial Plateau Fractures

Tibial Plateau Fractures

United States
Roswell Park Cancer Institute

Completed

Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8

United States
Stanford University

Completed

Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

Breast - Female

United States
University of Utah

Enrolling by invitation

Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures

Ankle Fractures

United States
University of California, Davis

Completed

A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine

Chronic Pain

3

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