Search clinical trials for: Sublingual alprazolam

Total 386 results

INSYS Therapeutics Inc

Completed

Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative Pain

Pain, Postoperative

United States
Xijing Hospital

Unknown

Efficacy and Safety of Zolmitriptan by Sublingual Administration

Cluster Headache
University of British Columbia

Not yet recruiting

Vitamin B12 and Folinic Acid Supplementation in Mitochondrial DNA Deletion Syndromes

Mitochondrial DNA Deletion | Macrocytosis
Indivior Inc.

Completed

Study to Assess Repeated Doses of INDV-2000 in Healthy Volunteers and in Treatment Seeking Individuals With Opioid Use Disorder

Healthy Volunteer | Opioid-use Disorder

United States
INSYS Therapeutics Inc

Completed

Fentanyl Sublingual Spray in Opioid Naive Participants

Pharmacology

United States
Indivior Inc.

Completed

Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid Disorder

Opioid Use Disorder

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Vildagliptin vs. Thiazolidinedione as add-on Therapy to Metformin in Patients With Type 2 Diabetes Not Controlled With Metformin Alone

Diabetes Mellitus, Type 2

United States
NYU Langone Health
NYC Health + Hospitals

Completed

XRB vs. SLB in Jail and at Re-entry: Pilot, Proof of Concept

Opioid Dependence

United States
M.D. Anderson Cancer Center
INSYS Therapeutics Inc

Terminated

Sublingual Fentanyl for the Management of Breakthrough Pain

Advanced Cancers

United States
McGill University

Unknown

Effect of Sublingual Fentanyl on Breathlessness in COPD

Copd
IRCCS San Raffaele

Unknown

Acute Post-operative Pain in Colon Resections (ERAS-PO)

Analgesia

Italy
Indivior Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Depot Buprenorphine at Three Different Molecular Weights in Treatment-Seeking Subjects With Opioid Use Disorder

Opioid Use Disorder

United States
NYU Langone Health

Not yet recruiting

Pilot Study of Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia

Familial Dysautonomia

United States
University of Arizona
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome (MOSAIC)

Obstructive Sleep Apnea | Down Syndrome

United States
Jeff C. Huffman, MD
BioXcel Therapeutics Inc

Withdrawn

Dexmedetomidine Sublingual Film for the Management of Agitation in Delirium: Safety and Preliminary Efficacy

Delirium
Janssen-Cilag International NV

Completed

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder (ESCAPE-TRD)

Depressive Disorder, Major

Israel, Hungary, Korea, Republic of, Taiwan, Portugal, Turkey, Germany, Malaysia, Denmark, Bulgaria, Czechia, Belgium, Poland, Brazil, Netherlands, Argentina, Finland, Greece, South Africa, Austria, Kazakhstan, Norway, Sweden, United...
Vanderbilt University

Active, not recruiting

Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension

Hypertension

United States
Medical College of Wisconsin

Terminated

Coagulation and Fibrinolysis of Estradiol in Transwomen

Transgenderism | Clotting Disorder

United States
Nourhan M.Aly
Alexandria University

Completed

Sublingual Versus Intranasal Administration of Dexmedetomidine for Sedation of Children Undergoing Dental Treatment

Moderate Sedation | Anti-anxiety Agents

Egypt
AcelRx Pharmaceuticals, Inc.

Completed

Efficacy and Safety Trial to Evaluate the Sufentanil NanoTab® PCA System/15 mcg (Zalviso™) for Post-Operative Pain in Patients After Knee or Hip Replacement Surgery

Post Operative Pain

United States
Teva GTC

Completed

Pilot, Proof-of-Concept Study of Sublingual Tizanidine in Children With Chronic Traumatic Brain Injury (TBI)

Traumatic Brain Injury

Israel
Yih-Ing Hser
National Institute on Drug Abuse (NIDA); University of California, Los Angeles and other collaborators

Not yet recruiting

Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) (RXR)

Substance-Related Disorders | Opioid-Related Disorders | Narcotic-Related Disorders

United States
M.D. Anderson Cancer Center
INSYS Therapeutics Inc

Completed

Fentanyl Sublingual Spray for Exercise-Induced Breakthrough Dyspnea

Advanced Cancers

United States
Wake Forest University Health Sciences

Terminated

Using Beta Blockers to Treat Mitral Regurgitation (REGURG)

Mitral Regurgitation | Mitral Valve Insufficiency | Heart Disease | Heart Valve Disease

United States
iX Biopharma Ltd.

Completed

Crossover Study to Evaluate the PK Effects of Two Different Wafer Administration Protocols.

Pain

Australia
McNeil AB

Completed

Bioequivalence Between Two Oral Nicotine Sublingual Tablets, 2 mg and 4 mg

Tobacco Dependence

Sweden
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate A Range of Dose Levels of Ad26.ZEBOV and MVA-BN-Filo in Healthy Adult Participants

Healthy

United States
EMD Serono

Terminated

Luveris® (Lutropin Alfa for Injection) in Women With Hypogonadotropic Hypogonadism (Luteinizing Hormone [LH] Less Than [<] 1.2 International Unit Per Liter [IU/L])

Hypogonadotropic Hypogonadism

United States
Mclean Hospital

Terminated

Spectroscopic Imaging at 4T: A Drug Challenge Study (CEBRA2)

AOD Effects and Consequences

United States
Vita Green Health Products Co. Ltd

Not yet recruiting

Pharmacokinetic and Pharmacodynamic Study of a Novel Sublingual Aspirin Tablet

Cardiovascular Diseases
Pharmaceutical Productions Inc.
National Institute on Drug Abuse (NIDA)

Completed

Pilot Pharmacokinetic Study of Investigational Sublingual Nicotine Tablet Versus COMMIT Nicotine Lozenge

Nicotine Pharmacokinetic Study

United States
iX Biopharma Ltd.
Jean Brown Research

Completed

A Study Of The Effectiveness Of Wafermine Alone And In Combination With Opioids In Subjects Undergoing Bunionectomy

Acute Pain

United States
German Breast Group

Completed

A Study to Compare ETC vs. EC-TX and Ibandronate vs. Observation in Patients With Node-positive Primary Breast Cancer (GAIN)

Breast Cancer

Germany
Centre Hospitalier Universitaire de Tivoli

Completed

Sufentanil Sublingual Tablet System for Postoperative Pain Management After Total Knee Arthroplasty

Postoperative Pain

Belgium
Friends Research Institute, Inc.
Rose Research Center, LLC

Completed

Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers

Tobacco Use Disorder | Cigarette Smoking

United States
UbiVac
National Cancer Institute (NCI); Mayo Clinic; Louisiana State University Health... and other collaborators

Completed

Combination Vaccine Immunotherapy (DRibbles) for Patients With Definitively-Treated Stage III Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
AcelRx Pharmaceuticals, Inc.

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™) for the Treatment of Post-Operative Pain in Patients After Open Abdominal Surgery

Post-Operative Pain

United States
Teva GTC

Terminated

One Year Extension Study To Protocol C2/5/TZ:MS-05

Multiple Sclerosis | Spasticity

Israel
Teva GTC

Completed

Study of Nighttime Dosing of Sublingual Tizanidine (12 mg) in Multiple Sclerosis (MS) Patients With Significant Spasticity

Muscle Spasticity

Israel
Damanhour University

Recruiting

Vildagliptin Versus Glimepiride in Type 2 Diabetic Patients

Type 2 Diabetes

Egypt
Limbic Medical
Enovex Pharmacy

Unknown

Micro-Dose, Macro-Impact: Leveraging Psychedelics in Frontline Healthcare Workers During the COVID-19 Pandemic

Acute Stress Disorder

United States
Transcept Pharmaceuticals

Completed

A Study of Zolpidem Tartrate Sublingual Tablet in Adult Patients With Insomnia

Insomnia

United States
Emory University
National Institute of Mental Health (NIMH)

Completed

D-cycloserine and Virtual Reality Exposure to Treat Iraq War Veterans With PTSD

Stress Disorder, Post Traumatic

United States
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder (SERENITY II)

Bipolar Disorder | Agitation,Psychomotor | Agitation Associated With Bipolar Disorder

United States
Brigham and Women's Hospital

Not yet recruiting

Pilot Study 1: Efficacy and Safety of Sublingual Dexmedetomidine (BXCL501) for the Treatment of Agitation in the Emergency Department

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Agitation | Schizophreniform Disorders
BioXcel Therapeutics Inc
Lotus Clinical Research, LLC

Completed

Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disorder

Schizophrenia | Bipolar Disorder | Schizo Affective Disorder | Agitation,Psychomotor | Schizophreniform Disorders

United States
University Hospital, Antwerp
Universiteit Antwerpen

Completed

Sublingual Sufentanil Tablet System (SSTS) Versus Intravenous Patient Controlled Analgesia After Back Surgery.

Pain, Postoperative

Belgium
AcelRx Pharmaceuticals, Inc.

Completed

Effect of Delivery Route on PK of Sufentanil NanoTab

Pharmacokinetics

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Trial of Pregabalin, Alprazolam, and Placebo in Subjects With Anxiety Prior to Dental Procedure

Dental Anxiety

Germany, United Kingdom
Merck KGaA, Darmstadt, Germany

Completed

Investigation of a Long-Acting Follicle Stimulating Hormone in Infertile Women Undergoing Assisted Reproductive Technology (ART)

Infertility

United States

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