Search clinical trials for: TAK-994

Total 4962 results

Kirby Institute

Not yet recruiting

Optimising Metabolic Management for People With Human Immunodeficiency Virus (HIV) on Integrase Based Antiretroviral Therapy (ART) (OPTIMAR)

HIV Infections | Weight Gain
Medical College of Wisconsin

Recruiting

Bortezomib, Isatuximab, Cyclophosphamide and Dexamethasone Induction in Transplant-Eligible Multiple Myeloma Patients (VICD)

Multiple Myeloma

United States
Boston Children's Hospital
Massachusetts General Hospital; Mayo Clinic; Karolinska University Hospital; Baylor... and other collaborators

Active, not recruiting

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Aplastic Anemia | Dyskeratosis Congenita | Hoyeraal Hreidarsson Syndrome | Revesz Syndrome

United States, Norway, Sweden
Gilead Sciences

Active, not recruiting

Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection (PURPOSE 2)

Pre-Exposure Prophylaxis of HIV Infection

United States, Thailand, Brazil, Peru, Argentina, South Africa, Mexico, Puerto Rico
Northern Jiangsu People's Hospital

Completed

Apixaban Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal Disconnection (ESAPT)

Venous Thrombosis | Cirrhosis | Hypertension, Portal | Splenectomy

China
University of Nebraska
National Cancer Institute (NCI)

Completed

Cyclophosphamide and Paclitaxel With or Without Trastuzumab in Stage I-II Breast Cancer Who Have Undergone Surgery

Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer

United States
Aileron Therapeutics, Inc.

Terminated

A Study of ALRN-6924 for Protection of Chemotherapy-Induced Side Effects in Patients With TP53-Mutant Breast Cancer

Prevention of Chemotherapy-induced Myelosuppression

United States, Bosnia and Herzegovina, Serbia, Bulgaria
Nova Scotia Health Authority

Completed

Postoperative Pain Control for Prostatectomy (TAP)

Prostate Cancer

Canada
Grupo Español de Linfomas y Transplante Autólogo...

Terminated

Cyclosporine Plus Methotrexate or Alemtuzumab

Unrecognized Condition: Mature B or T-cell Neoplasm

Spain, Poland
Istituto Scientifico H. San Raffaele

Unknown

Study of Blood and Tissue Samples in Predicting Response to Second-Line Therapy Using Erlotinib Hydrochloride or Chemotherapy in Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

Italy
National Eye Institute (NEI)
QLT Inc.

Terminated

TAC-PF, Avastin® in Combination With Photodynamic Therapy to Treat Age Related Macular Degeneration (VERTACL)

Age-Related Macular Degeneration

United States
Icahn School of Medicine at Mount Sinai

Recruiting

Psychopharmacological Treatment of Emotional Distress

Psychological Distress | Suicide Crisis Syndrome

United States
Laboratorios Poen

Completed

Efficacy and Toxicity of Bepotastine 1,5% PF vs Olopatadine 0,2% With BAK on Allergic Conjunctivitis Treatment

Allergic Conjunctivitis

Argentina
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Switching From Regimens Consisting of Boosted Atazanavir or Darunavir Plus Either Emtricitabine/Tenofovir or Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed HIV-1 Infected Adults

HIV-1 Infection

Spain, United States, France, Germany, United Kingdom, Italy, Canada, Australia, Belgium, Puerto Rico, Dominican Republic
Otsuka Beijing Research Institute

Completed

Aripiprazole IM Depot in the Acute Treatment of Adults With Schizophrenia

Schizophrenia

China
Military Hospital of Tunis

Completed

Treatment of Corneal Infiltrates Secondary to Epidemic Keratoconjunctivitis

Adenoviral Keratoconjunctivitis

Tunisia
Hanlim Pharm. Co., Ltd.

Completed

Evaluation of the Efficacy and Safety of Entelon Tab. 150mg in Patients With Osteoarthritis of Knee

Knee Osteoarthritis

Korea, Republic of
Region Gävleborg
Malmö University; Swedish Dental Associations Scientific Funds; Department of... and other collaborators

Completed

Miniscrews as Anchorage Device for Orthodontic Treatment

Orthodontic Anchorage Procedures | Orthodontic Space Closure

Sweden
Masonic Cancer Center, University of Minnesota
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

Head and Neck Cancer

United States
Novartis

Completed

Evaluation of the Therapeutic Benefit of an Initial Intensified Dosing Regimen of Mycophenolate Sodium Versus a Standard Regimen in Renal Transplant Patients

Kidney Transplantation

Switzerland
Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain
Eben Rosenthal
National Cancer Institute (NCI)

Completed

Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Head and Neck (SCCHN)

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Combination Chemotherapy in Patients With Lymph Node Positive Breast Cancer

Male Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma

Pleural Malignant Mesothelioma

United States, Canada
University of California, San Francisco
Incyte Corporation

Not yet recruiting

Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)

Hemophagocytic Lymphohistiocytoses

United States
Mayo Clinic

Recruiting

Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma in Patients Undergoing Craniotomy

Recurrent Glioblastoma

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Immunoclassification of Psoriasis: a Strategy for Precision Medicine

Psoriasis | Immunoclassification

China
Royal Marsden NHS Foundation Trust
Pfizer; AstraZeneca; Institute of Cancer Research, United Kingdom; UNICANCER; Gustave... and other collaborators

Recruiting

A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer (TRAK-ER)

HER2-negative Breast Cancer | ER+ Breast Cancer

United Kingdom, France
Michael Evans
National Institute of Mental Health (NIMH); U.S. Army Medical Research Acquisition...

Recruiting

11C-YJH08 PET Imaging for the Detection of Glucocorticoid Receptor Expression in Patients With Metastatic Prostate Cancer

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
Peking University People's Hospital
Beijing Friendship Hospital; Beijing Hospital; The First Affiliated Hospital... and other collaborators

Recruiting

The Combination of Tacrolimus and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia

Immune Thrombocytopenia | ITP

China
Sun Yat-sen University

Recruiting

The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) Versus Adjuvant Transarterial Chemoembolization (TACE) for Patients With Hepatocellular Carcinoma And Portal Vein Tumor Thrombosis (PVTT) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.

Hepatocellular Carcinoma

China
Yonsei University

Completed

Effect of Baclofen Treatment on Nocturnal Muscle Cramps in Patients With Lumbar Spinal Stenosis: a Randomized Clinical Trial

Lumbar Spinal Stenosis With Nocturnal Calf Cramps

Korea, Republic of
Peking Union Medical College Hospital
Gilead Sciences

Active, not recruiting

Biktarvy in Treatment-Naïve Late Presenters With HIV-1 Infection

HIV-1-infection

China
Assiut University

Completed

Evening Primrose Oil to Misoprostol During Induction of Second-trimester Missed Miscarriage

Missed Abortion

Egypt
AbbVie

Completed

Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With Low-Dose Ribavirin QD in Subjects With Genotype 1a Chronic Hepatitis C Virus Infection (GEODE II)

Hepatitis C Virus (HCV)
AbbVie

Completed

ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Treatment-Naïve and Treatment-Experienced, Non-Cirrhotic Asian Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection

Hepatitis C Virus (HCV)
AbbVie

Completed

A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in US Veterans With Genotype 1 Chronic Hepatitis C Virus Infection

Cirrhosis | Chronic Hepatitis C | Hepatitis C Virus
AstraZeneca

Completed

Comparison Between Symbicort® and Prednisolone in COPD (SPACE)

Chronic Obstructive Pulmonary Disease

Sweden, Germany, Norway, Denmark, Finland
Abbott

Completed

Blood Pressure and Weight Trajectory on a Dual Antihypertensive Combination Plus Sibutramine Versus Placebo in Obese Hypertensives (HOS)

Hypertension | Obesity
Benazir Bhutto Hospital, Rawalpindi

Completed

Role of Emotional Freedom Techniques in Reducing Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy (EFT)

Postoperative Nausea and Vomiting

Pakistan
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Pentoxifylline Plus Carvedilol vs Carvedilol Monotherapy in Preventing New Decompensation in Stable Cirrhotic Patients With Prior Decompensation

Liver Cirrhosis

India
University of Washington

Recruiting

Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

Acute Myeloid Leukemia | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm | Secondary Myelofibrosis | Myeloproliferative Neoplasm, Unclassifiable

United States
Michał Borys

Completed

Comparison of Two Pain-treatment Techniques After Cesarean Section

Cesarean Section | Pain Management | Neuropathic Pain

Poland
Biokosmes Srl
Opera CRO, a TIGERMED Group Company

Completed

Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash

Oral Hygiene | Dental Plaque | Toothbrushing

Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); EMD Serono

Terminated

Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma

Stage IV Merkel Cell Carcinoma AJCC v7 | Merkel Cell Polyomavirus Infection

United States
BeyondSpring Pharmaceuticals Inc.

Active, not recruiting

Plinabulin vs. Pegfilgrastim in Prevention of TAC Induced Neutropenia

Chemotherapy-induced Neutropenia

China, Ukraine
Medical University of Lublin

Unknown

TAP vs QLB in Patients After Cesarean Delivery

Postoperative Pain | Cesarean Section
AbbVie

Terminated

A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/r With or Without Dasabuvir and With or Without Ribavirin in Chronic Hepatitis C Virus Genotype 1 or 4 Infected Adults With Successfully Treated Early Stage Hepatocellular Carcinoma (GEODE - I)

Chronic Hepatitis C Infection
Benno Rehberg-Klug
Domitille Dereu

Completed

Transversus Abdominis Plane (TAP) Block Versus Intrathecal Morphine for Caesarean Section - Randomised Controlled Trial (MOTAP)

Postoperative Pain

Switzerland
IlDong Pharmaceutical Co Ltd

Completed

Compare the Pharmacokinetics of TAH(80/10/12.5) Tablet in Comparison to the Co-administration of Telmisartan, Amlodipine and Hydrochlorothiazide in Healthy Male Volunteers

Healthy

Korea, Republic of

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