Search clinical trials for: TOL-3021 Placebo

Total 62643 results

ANRS, Emerging Infectious Diseases

Not yet recruiting

Study Evaluating the Safety, in Terms of HBV Virological Control at 96 Weeks, of 2 Antiviral Treatment Relief Strategies, in Patients Co-infected With the HIV-1 and HBV Viruses (BI-LIGHT)

HIV Infections | HBV Coinfection
University College, London
National Institute for Health Research, United Kingdom

Recruiting

PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients (PITSTOP)

Head and Neck Fibrosis

United Kingdom
AbbVie

Completed

A Study to Evaluate Satisfaction in Adult Participants With the Aesthetics of the Periorbital Area After JUVÉDERM® Fillers and BOTOX®/VISTABEL® Injections

Facial Corrections | Facial Lines

Australia, Belgium
Dana-Farber Cancer Institute
Novartis

Completed

Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALL (CRAD001NUS175T)

Acute Lymphoblastic Leukemia

United States
Institut de Recherches Cliniques de Montreal
McGill University

Withdrawn

Carbohydrates Under Target for Type 1 Diabetes Management

Type 1 Diabetes

Canada
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Hypercholesterolemia

Slovenia, Taiwan, Russian Federation, Canada, Netherlands, Brazil, Denmark, Mexico, Spain, Turkey
Seng Gee Lim
Merck Sharp & Dohme LLC; Singapore General Hospital; Tan Tock Seng Hospital; Changi... and other collaborators

Completed

Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy (SWAP)

Chronic Hepatitis B

Singapore
Ministry of Health, Jamaica
University Hospital of the West Indies

Completed

Penile Fracture: A Comparison of Erectile Function After Immediate Repair Versus Delayed Repair

Erectile Dysfunction

Jamaica
Nationwide Children's Hospital

Withdrawn

Autologous Stem Cell Transplant for Refractory Crohn's Disease

Crohn's Disease
Janssen R&D Ireland

Completed

A Study to Evaluate the Safety, Tolerability, and Effectiveness of a 12-Week Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Patients Infected With Chronic Genotype 1 Hepatitis C Virus

Chronic Hepatitis C

Belgium, Germany
Rambam Health Care Campus

Completed

Prospective Evaluation of the Efficacy of Palivizumab Administration in Children Born at 29-32 Weeks of Gestation

Bronchial Hyperreactivity | Infant, Premature

Israel
Assistance Publique - Hôpitaux de Paris

Completed

Molecular Detection of Antibiotic Resistance and H Pylori Eradication (HELICOSTIC)

Helicobacter Pylori Infection

France
Riverside Haematology Group

Unknown

Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United Kingdom
Medical University of Lodz

Unknown

Assessment of Utility of Exhaled Nitric Oxide Measurement for Treatment Monitoring in Children With Asthma

Asthma

Poland
Ping-I (William) Hsu, M.D.

Completed

Efficacies of Two Bismuth Quadruple Therapies in the Second-line Treatment of H Pylori Infection

Helicobacter Pylori Infection

Taiwan
Alexion

Completed

Phase 1 Study of ALXN1840 on the Metabolism of a CYP2C9 Substrate in Healthy Participants.

Wilson Disease

United States
Aquestive Therapeutics
Syneos Health; Covance

Completed

Safety and Tolerability Study of Diazepam Buccal Film (DBF) in Subjects With Epilepsy (DBF)

Epilepsy

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted At Bedtime Or Immediately Following A 400-500 or 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Menarini International Operations Luxembourg SA

Completed

Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout (FORWARD)

Gout

Poland, Serbia, Germany, Italy, Netherlands, Romania
Pawel Kalinski

Withdrawn

A Study of Type-1 Polarized Dendritic Cell (αDC1) Vaccine in Combination With Tumor-Selective Chemokine Modulation (Interferon-α2b, Rintatolimod, and Celecoxib) in Subjects With Chemo-Refractory Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

United States
Beijing Friendship Hospital
Beijing Tiantan Hospital

Recruiting

Comparison of the Effects of Esketamine, Sufentanil, or Lidocaine on Tussis Reflection During Upper Gastroscopy

Anesthesia

China
Timothy Ekhlassi

Enrolling by invitation

Comparison of Two Different Concentrations of Local Anesthetic in Patient Reported Pain in Oculoplastic Surgery

Pain | Dermatochalasis | Dermatochalasis of Eyelid | Dermatochalasis of Both Upper Eyelids | Dermatochalasis of Both Eyes | Dermatochalasis of Right Upper Eyelid | Dermatochalasis of Left Upper Eyelid

Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Active, not recruiting

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

Prostate Cancer

United States, Canada
Azidus Brasil

Suspended

Efficacy and Comparative of the Association Beclomethasone Clotrimzaol + Gentamicin in Patients With Acne Contaminated (acne)

Folliculitis

Brazil
Masonic Cancer Center, University of Minnesota

Terminated

T-Cell Depleted Double UCB for Refractory AML

Acute Myelogenous Leukemia | Refractory Acute Myelogenous Leukemia

United States
Leukemia Research Fund

Completed

Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
European Institute of Oncology

Unknown

Biological Therapy With Combination Chemotherapy in Patients With Colorectal Cancer

Colorectal Cancer

Italy, Korea, Republic of, Greece
Roswell Park Cancer Institute

Completed

High Dose Chemotherapy, Peripheral Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Acute Myeloid Leukemia

Leukemia

United States
Université de Sherbrooke
Ethicon, Inc.

Completed

Safety and Efficacy Study on the Implantation of the Tension-Free Vaginal Tape (TVT-Secur) Under Local Anesthesia

Urinary Stress Incontinence

Canada
Poitiers University Hospital

Completed

Maintenance Neoral Monotherapy Compared to Bitherapy in Renal Transplantation

Kidney Transplantation

France
University Hospital of Patras

Completed

Effect of Topical and Oral Diclofenac on Pain Related to Intravitreal Injections

Pain

Greece
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Incyte Corporation

Active, not recruiting

JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis

Primary Myelofibrosis | Secondary Myelofibrosis

United States
University of Copenhagen

Completed

Pharmacological Properties of Salmeterol

Pharmacokinetics in Healthy Young Men

Denmark
PETHEMA Foundation
Bristol-Myers Squibb; Sanofi; Adknoma; Start from scratch

Not yet recruiting

NDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-Iberdomide (GEM21menos65)

Newly Diagnosed Multiple Myeloma

Spain
Guangdong Provincial People's Hospital

Recruiting

Comparison of BTD and BCD Based Regimens in the Treatment of AL Amyloidosis

Immunoglobulin Light-Chain Amyloidosis

China
Duke University
Millennium Pharmaceuticals, Inc.; Duke Cancer Institute

Terminated

Velcade + Cyclophosphamide in Newly Diagnosed Multiple Myeloma

Multiple Myeloma

United States
University of Washington
National Cancer Institute (NCI)

Terminated

Radiation Therapy, Cisplatin, and Etoposide in Treating Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IIB Non-small Cell Lung Cancer

United States
M.D. Anderson Cancer Center
Celgene Corporation

Completed

Temozolomide, Thalidomide, and Lomustine (TTL) in Melanoma Patients

Melanoma | Brain Neoplasms

United States
Massachusetts General Hospital

Completed

Lenalidomide/Bortezomib/Dexamethasone for Multiple Myeloma (MM) (RVD Lite)

Multiple Myeloma

United States
University of California, Davis
Eli Lilly and Company

Completed

Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors

Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
New Mexico Cancer Care Alliance

Completed

Availability & Effect of Post-OP Ketorolac on Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer

United States
Egalet Ltd

Completed

Study to Determine the Tolerability, Safety and Pharmacokinetics of Ketorolac Tromethamine by Intranasal Administration in Healthy Volunteers

Healthy Volunteers

United Kingdom
3M

Completed

Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty (PROMISES)

Pathologic Processes | Wounds and Injuries | Postoperative Complications | Surgical Wound | Infection | Musculoskeletal Disease | Prosthesis-Related Infections | Joint Disease | Revision Total Knee Arthroplasty

United States
The Lymphoma Academic Research Organisation
Millennium Pharmaceuticals, Inc.

Completed

Brentuximab Vedotin in Refractory/Relapsed Hodgkin Lymphoma Treated by ICE (BV-ICE)

Hodgkin Disease

France, Belgium
Boehringer Ingelheim

Completed

Open Label Study of NVP+CBV Treatment in Women Who Have Received sdNVP for the pMTCT of HIV

Acquired Immunodeficiency Syndrome

South Africa
Redar
Institut National de la Santé Et de la Recherche Médicale, France; Fondation... and other collaborators

Unknown

Ketamine's Efficiency in the Treatment of Chronic Pain: Kynurenin Pathway (KEKU1)

Inflammation | Chronic Pain | Neuralgia

France
Royan Institute

Completed

The Effect of Ethinyl Estradiol on Polycystic Ovary Syndrome Women Undergoing Intrauterine Insemination

Infertility

Iran, Islamic Republic of
Eurofarma Laboratorios S.A.

Withdrawn

A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study (SAVE)

Knee Osteoarthritis
University Hospital, Montpellier
National and Kapodistrian University of Athens; University of Manchester; University... and other collaborators

Not yet recruiting

Study of Indoor Air Pollutants and Their Impact in Childhood Health and Wellbeing (SynAIR-G)

Allergy | Asthma in Children

France
Vrije Universiteit Brussel

Recruiting

The Use of Lidocaine Gel Versus Subconjunctival Xylocaine Injection in Pterygium Excision (LIDPTER)

Pterygium

Belgium

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