Search clinical trials for: Tafenoquine Control

Total 64172 results

GlaxoSmithKline
Parexel; Medicines for Malaria Venture

Completed

A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution

Malaria, Vivax

United States
U.S. Army Medical Research and Development Command
SmithKline Beecham

Completed

A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium Falciparum

Malaria
GlaxoSmithKline

Completed

Tafenoquine Thorough QTc Study in Healthy Subjects

Malaria, Vivax

United States
Naval Medical Research Center
The 108 Military Central Hospital; Naval Medical Research Unit TWO (NAMRU-2); Australian Defence Force Malaria and Infectious Disease Institute (ADF MIDI) and other collaborators

Not yet recruiting

Escalating Monthly Doses of Tafenoquine in Healthy Volunteers (TQ)

Prophylaxis

Vietnam
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Assessment of Any Potential Retinal Effects of Tafenoquine (TQ)

Malaria, Vivax

United States
60P Australia Pty Ltd

Not yet recruiting

A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease Progression

Infectious Disease | SARS-CoV-2 | Severe Acute Respiratory Syndrome Coronavirus 2 | COVID 19 Disease | Mild to Moderate COVID 19 Disease
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse

Malaria, Vivax

Thailand, India, Brazil, Ethiopia, Peru, Bangladesh, Cambodia, Philippines
60 Degrees Pharmaceuticals LLC

Completed

Tafenoquine in Patients With Mild to Moderate COVID-19

COVID 19 Disease

United States
Shoklo Malaria Research Unit
Mahidol Oxford Tropical Medicine Research Unit

Recruiting

ACT vs CQ With Tafenoquine for P. Vivax Mono-infection (ACTQ)

Malaria | Malaria, Vivax | Plasmodium Vivax Malaria

Thailand
London School of Hygiene and Tropical Medicine

Completed

Single Low Dose Tafenoquine to Reduce P. Falciparum Transmission in Mali (NECTAR2) (NECTAR2)

Malaria, Falciparum

Mali
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria

Malaria, Vivax

Thailand, Vietnam, Colombia, Brazil, Ethiopia, Peru
60 Degrees Pharmaceuticals LLC

Completed

Long-Term Safety Study of Tafenoquine

Healthy Volunteers

Australia, United States
60 Degrees Pharmaceuticals LLC

Not yet recruiting

Oral Tafenoquine Plus Standard of Care Versus Placebo Plus Standard of Care for Babesiosis

Babesiosis
Fundação de Medicina Tropical Dr. Heitor Vieira...
Ministry of Health, Brazil; Medicines for Malaria Venture; Centro de Pesquisa... and other collaborators

Active, not recruiting

Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitative G6PD Testing in Brazil (Trust)

Malaria, Vivax | G6PD Deficiency

Brazil
U.S. Army Medical Research and Development Command
SmithKline Beecham

Completed

Evaluation of Weekly Tafenoquine

Malaria
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) Malaria

Malaria, Vivax

Indonesia
Centre Hospitalier de Cayenne
Oswaldo Cruz Foundation

Recruiting

Radical CUREfor MAlaria Among Highly Mobile and Hard-to-reach Populations in the Guyanese Shield (CUREMA)

Malaria, Vivax

Brazil, Suriname
U.S. Army Medical Research and Development Command
SmithKline Beecham

Completed

An Evaluation of Weekly Tafenoquine

Falciparum Parasitaemia
Menzies School of Health Research
Aga Khan University; University of Melbourne; Universitas Sumatera Utara; Ethiopian... and other collaborators

Recruiting

Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine (EFFORT)

Vivax Malaria | Malaria, Vivax | Plasmodium Vivax | Malaria Relapse

Cambodia, Ethiopia, Indonesia, Pakistan
Menzies School of Health Research
University of Melbourne; Curtin University; Addis Ababa University; Fundação de... and other collaborators

Not yet recruiting

A Revised Tafenoquine Dose to Improve Radical Cure for Vivax Malaria (TADORE)

Vivax Malaria

Brazil, Ethiopia, Indonesia, Papua New Guinea
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Withdrawn

Tafenoquine and Primaquine in Colostrum and Breast Milk (TBM)

Healthy Lactating Women

Thailand
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Tafenoquine/Chloroquine DDI Study

Malaria

United States
GlaxoSmithKline
Medicines for Malaria Venture

Completed

A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria

Malaria, Vivax

Vietnam, Colombia
Marinus Pharmaceuticals

Completed

A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression

Behavioral Symptoms | Depressive Disorder | Depression | Mood Disorders | Pregnancy Complications | Depression, Postpartum | Mental Disorder | Postpartum Disorder | PPD | Postpartum Blues

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline

Terminated

Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults

Malaria | Plasmodium Vivax

Thailand
GlaxoSmithKline
Medicines for Malaria Venture

Completed

G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)

Malaria

Thailand
Dr. Prayuth Sudathip
Medicines for Malaria Venture

Completed

Operational Feasibility of Appropriate Plasmodium Vivax Radical Cure After G6PD Testing in Thailand (ARCTIC)

Malaria, Vivax | G6PD Deficiency

Thailand
GlaxoSmithKline
Medicines for Malaria Venture

Completed

A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate

Malaria, Vivax

United States
University of Oxford
PATH

Not yet recruiting

Southeast Asia Dose Optimization of Tafenoquine (SEADOT)

Plasmodium Vivax Malaria

Cambodia, Lao People's Democratic Republic, Thailand, Vietnam
St. Jude Children's Research Hospital
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Children With Refractory or Recurrent Neuroblastoma

Neuroblastoma

United States
Medicines for Malaria Venture
UNITAID; Universidad Peruana Cayetano Heredia; ICON plc

Recruiting

Radical Cure (RC) With Tafenoquine or Primaquine After Semi-quantitative G6PD Testing: A Feasibility Study in Peru

Malaria, Vivax

Peru
Nantes University Hospital

Terminated

Register and DNA Bank of Adult Extra-hospital Sudden Death (Protocol FASTER)

Extra-hospital Sudden Death

France
GlaxoSmithKline

Completed

A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive

Denture Retention

United States
Charite University, Berlin, Germany
Freie Universität Berlin

Unknown

Cognitive Training to Improve Cognitive Function Following Chemotherapy (KT)

Cognitive Dysfunction

Germany
Postgraduate Institute of Medical Education and...

Completed

Closed Loop Isoflurane Administration With Bispectral Index in Open Heart Surgery

Open Heart Surgery

India
Yonsei University

Completed

The Effect of Pressure Controlled Ventilation on the Pulmonary Mechanics in Prone Position Using the Wilson Frame: A Comparison With Volume Controlled Ventilation

Herniation of Lumbar Vertebral Disc

Korea, Republic of
Florida State University

Recruiting

Central Executive Training (CET) for ADHD

ADHD

United States
Inje University

Recruiting

Effect of Remimazolam on Postoperative Nausea and Vomiting

Postoperative Nausea and Vomiting

Korea, Republic of
Federico II University

Completed

Fiber-enriched Croissant Consumption and Effects on Metabolic Status, Appetite and Gut Microbiota (CROMA)

Healthy | Overweight and Obesity

Italy
Assistance Publique - Hôpitaux de Paris

Completed

Identification and Dynamics With Cerebral Functional Magnetic Resonance Imaging (CHAOSBOLD)

Chronic Obstructive Pulmonary Disease

France
Yonsei University

Completed

Effect of Intraoperative Nociception Control Based on Analgesia Nociception Index (ANI) Monitoring on Stress Response During Total Laparoscopic Hysterectomy

Patients Undergoing Total Laparoscopic Hysterectomy

Korea, Republic of
Milton S. Hershey Medical Center

Completed

The Effect of Jazz on Postoperative Pain and Stress in Patients Undergoing Elective Hysterectomy

Pain | Anxiety

United States
South Tees Hospitals NHS Foundation Trust
Vyaire Medical

Completed

Automatic Oxygen Control for Reducing Extremes of Oxygen Saturation (AreOS): A Randomised Control Trial (AreOS)

Prematurity

United Kingdom
Zonguldak Bulent Ecevit University

Not yet recruiting

Effect of Stress Ball Use on Anxiety Level During Endometrial Biopsy Procedure

Endometrial Hyperplasia | Endometrial Neoplasms | Biopsy Wound
Association pour le Développement et l'Organisation...

Completed

Sensory and Emotional Modulation of Dyspnea Under Artificial Ventilation in the Intensive Care Unit (Sensopnée2)

Dyspnea

France
St Patrick's Hospital, Ireland

Unknown

The Effectiveness of a Smartphone Application in the Treatment of Alcohol Use Disorder

Alcohol Use Disorder

Ireland
University of Kentucky
National Institute on Drug Abuse (NIDA)

Completed

A Feasibility Trial for Inhibitory-Control Training to Reduce Cocaine Use (RCT(01))

Cocaine Use Disorder

United States
Abant Izzet Baysal University

Completed

Effectiveness of Kinesio Taping On Balance In Patients With Stroke

Stroke

Turkey
Faculdade de Ciências Médicas da Santa Casa de...

Completed

Pre Warming Protocol Implementation in Operation Room

Hypothermia

Brazil
Tampere University Hospital

Completed

SPI Value Relevance in Clinical Practice (SPIrelevance)

Anesthesia

Finland

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