Search clinical trials for: Temodar and O6-Benzylguanine

Total 408 results

Roswell Park Cancer Institute

Active, not recruiting

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma | Gliosarcoma

United States
Merck Sharp & Dohme LLC
AESCA Pharma GmbH

Terminated

Safety and Tolerability of Low-Dose Temozolomide During Whole Brain Radiation in Patients With Cerebral Metastases From Non-Small-Cell Lung Cancer (Study P04071)(TERMINATED)

Carcinoma, Non-Small-Cell Lung
National Cancer Institute (NCI)

Active, not recruiting

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma

United States, Canada, Puerto Rico, Australia, New Zealand
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma | Gliosarcoma

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb

Terminated

Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastoma

Brain Diseases | Glioblastoma | CNS Disease

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastoma

Neuroblastoma

United States, Canada, Australia
Erasca, Inc.

Recruiting

A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)

Advanced or Metastatic NRAS-mutant Melanoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Paclitaxel and Carboplatin or Temozolomide in Treating Patients With Stage IV Melanoma

Melanoma (Skin)

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial

Malignant Solid Neoplasm | Adrenal Gland Pheochromocytoma | Paraganglioma | Hematopoietic and Lymphatic System Neoplasm

United States
Jonsson Comprehensive Cancer Center
Tesaro, Inc.; Translational Research in Oncology-U.S

Recruiting

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma | Stage IIIC Lung Cancer AJCC v8

United States
National Cancer Institute (NCI)

Completed

Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
Novartis Pharmaceuticals
Innovative Therapies For Children with Cancer Consortium

Recruiting

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Neuroblastoma

Germany, Italy, Singapore, Spain, United States, Australia, France
Abramson Cancer Center at Penn Medicine
Roswell Park Cancer Institute; CARTI

Recruiting

CapTemY90 for Grade 2 NET Liver Metastases (CapTemY90)

Neuroendocrine Tumors | Neuroendocrine Tumor Grade 2

United States
Armando Santoro, MD
GlaxoSmithKline; Istituto Clinico Humanitas

Not yet recruiting

Niraparib and Temozolomide in Patients Glioblastoma (ONC-2022-001)

Glioma, Malignant

Italy
University of Chicago

Recruiting

Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma

Malignant Glioma of Brain

United States
University of Colorado, Denver
Genentech, Inc.

Completed

Hypofractionated Intensity-Modulated Radiation Therapy With Temozolomide and Bevacizumab for Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma

Glioblastoma Multiforme

United States
Center for Neurosciences, Tucson
Genentech, Inc.

Completed

Bi-weekly Temozolomide Plus Bevacizumab for Adult Patients With Recurrent Glioblastoma Multiforme

Recurrent Glioblastoma Multiforme | Recurrent Gliosarcoma

United States
Northwestern University
National Cancer Institute (NCI)

Recruiting

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

Glioblastoma | Astrocytoma | Recurrent Glioblastoma | MGMT-Unmethylated Glioblastoma | Glioblastoma, IDH-Wildtype

United States
L. Nicolas Gonzalez Castro, MD, PhD
Merck Sharp & Dohme LLC

Recruiting

Surgical Pembro +/- Olaparib w TMZ for rGBM

Glioblastoma | Recurrent Glioblastoma

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Gliosarcoma | Supratentorial Glioblastoma

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Terminated

Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)

Brain Cancer | Glioblastoma Multiforme

United States
SCRI Development Innovations, LLC
Genentech, Inc.

Terminated

Study of High-Dose Rituximab With Temozolomide as Treatment for Primary Central Nervous System (CNS) Lymphoma

Primary Central Nervous System Lymphoma

United States
M.D. Anderson Cancer Center
Schering-Plough; Enzon Pharmaceuticals, Inc.

Terminated

DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis

Neoplastic Meningitis

United States
Wake Forest University Health Sciences
NovoCure Ltd.

Terminated

A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)

Cancer of Brain and Nervous System

United States
M.D. Anderson Cancer Center

Terminated

Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM

Glioblastoma Multiforme

United States
Actelion

Terminated

Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma

Glioblastoma

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomas

Glioblastoma | Gliosarcoma

United States
SentoClone AB

Unknown

SentoClone® Compared to Reference Treatment in Advanced Malignant Melanoma

Malignant Melanoma

Sweden
Northwestern University
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

Glioblastoma

United States
Joseph J. Cullen, MD, FACS
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Glioblastoma | Glioblastoma Multiforme | GBM

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBM

Glioblastoma Multiforme

United States
Washington University School of Medicine

Terminated

Neoepitope-based Personalized Vaccine Approach in Patients With Newly Diagnosed Glioblastoma

Glioblastoma Multiforme | Astrocytoma, Grade IV

United States
Nationwide Children's Hospital

Recruiting

NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab (STING)

Refractory Neuroblastoma | Relapsed Neuroblastoma

United States
Peking University Cancer Hospital & Institute

Unknown

HDI Versus Chemotherapy as Systemic Adjuvant Therapy for Resected Mucosal Melanoma

Melanoma

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); BeiGene

Completed

BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations

Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | IDH1 Mutation | IDH2 Mutation

United States
Duke University
Genentech, Inc.

Completed

Bevacizumab Beyond Progression (BBP) (BBP)

Glioblastoma | Malignant Glioma | Gliosarcoma | Grade 4 Malignant Glioma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

Glioblastoma | Gliosarcoma | Supratentorial Glioblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Central Nervous System Neoplasm | Spinal Cord Neoplasm

United States
University of Cincinnati

Recruiting

Study of Letrozole in Recurrent Gliomas

Brain Tumor

United States
National Cancer Institute (NCI)

Completed

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Untreated Childhood Brain Stem Glioma | Giant Cell Glioblastoma | Untreated Childhood Anaplastic Astrocytoma | Untreated Childhood Giant Cell Glioblastoma | Untreated Childhood Glioblastoma | Untreated Childhood Gliosarcoma | Brain Stem Glioma | Untreated... and other conditions

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Terminated

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States, Canada
Eric Thompson, M.D.
National Cancer Institute (NCI); National Institutes of Health (NIH); Annias...

Terminated

Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens (PERFORMANCE)

Glioblastoma | Glioblastoma Multiforme

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Brigham...

Completed

Thalidomide in Combination With Temodar in Patients With Neuroendocrine Tumors

Neuroendocrine Tumor

United States
Merck Sharp & Dohme LLC

Completed

Study of Temozolomide in Previously Untreated Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Participants With Low O6-Methylguanine Methyltransferase (MGMT) Expression (P05052) (TALL)

Myelodysplastic Syndrome | Leukemia, Acute Myeloid
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Doxycycline, Temozolomide and Ipilimumab in Melanoma

Melanoma

United States
M.D. Anderson Cancer Center

Completed

Aerosol L9-NC and Temozolomide in Ewing's Sarcoma

Ewing's Sarcoma

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Glioblastoma | Gliosarcoma

United States

Search clinical trials for: Temodar and O6-Benzylguanine

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