Search clinical trials for: Test drug 2

Total 263720 results

Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Switching From Regimens Consisting of Boosted Atazanavir or Darunavir Plus Either Emtricitabine/Tenofovir or Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed HIV-1 Infected Adults

HIV-1 Infection

Spain, United States, France, Germany, United Kingdom, Italy, Canada, Australia, Belgium, Puerto Rico, Dominican Republic
Temple University
Pfizer; Abbott

Terminated

Kaletra and Maraviroc in Antiretroviral Therapy (ART)-Naive Patients (KALMAR Study) (KALMAR)

HIV Infections

United States
Jonsson Comprehensive Cancer Center

Terminated

18F-Clofarabine PET/CT in Imaging Cancer Patients Before and After Interventions

Malignant Neoplasm

United States
Makerere University
Infectious Diseases Institute, Uganda

Unknown

Nucleosides And Darunavir/Dolutegravir In Africa (NADIA)

Human Immunodeficiency Virus

Uganda
University of Louisville

Completed

Intraoperative Amiodarone to Prevent Atrial Fibrillation in Lung Transplant Patients

Atrial Fibrillation | Lung Transplant; Complications

United States
Chromis LLC
Chemical Diversity Research Institute

Unknown

An Adaptive Study of Favipiravir Compared to Standard of Care in Hospitalized Patients With COVID-19

COVID-19

Russian Federation
Kirby Institute

Completed

Safety and Efficacy of Reduced Versus Standard Dose Efavirenz (EFV) Plus Two Nucleotides in Antiretroviral-naïve Adults. (ENCORE1)

HIV Infections

Australia
Ache Laboratorios Farmaceuticos S.A.

Completed

Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemia (LANCE)

Dyslipidemia | Hypercholesterolemia

Brazil
ADRIANO LAZZARIN, MD
Ministero della Salute, Italy

Unknown

Implication for Strategies of Long Term Control of Viral Replication in Patient With Primary HIV Infection (PHI). (P25-INACTION)

HIV-1-infection

Italy
ViiV Healthcare
GlaxoSmithKline

Completed

Study to Evaluate a HIV Drug for the Treatment of HIV Infection

HIV Infections | Infection, Human Immunodeficiency Virus

Germany
Sunshine Lake Pharma Co., Ltd.

Completed

A Drug-drug Interaction (DDI) Study of Morphothiadine Mesilate/Ritonavir in Healthy Subjects

Chronic Hepatitis B

China
University of California, Irvine

Terminated

Disulfiram Plus Arsenic Trioxide In Patients With Metastatic Melanoma and at Least One Prior Systemic Therapy

Metastatic Melanoma

United States
Memorial Sloan Kettering Cancer Center

Completed

Rapid Gastric and Pancreas Cancer Staging Utilizing Peritoneal Lavage

Gastric Cancer | Pancreatic Cancer

United States
Allergan

Completed

Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease

Dry Eye Syndromes

United States
Tuberculosis Research Centre, India

Completed

Comparing Daily vs Intermittent Regimen of ATT in HIV With Pulmonary Tuberculosis

HIV Infection | Pulmonary TB

India
Nourhan Hassan Osama Thuraya Mohamed
Ain Shams University

Completed

The Effect of Colistin Inhalation on Ventilator Associated Pneumonia

Ventilator Associated Pneumonia
Harvard University Faculty of Medicine
National Institute of Allergy and Infectious Diseases (NIAID); Sanofi; University... and other collaborators

Completed

Trial of High-Dose Rifampin in Patients With TB (HIRIF)

Tuberculosis

United States, Peru, United Kingdom
Boston University
University of Florida; Westat

Withdrawn

Efficacy and Tolerability of Delamanid, Linezolid, Pyrazinamide and Levofloxacin (DAZZLE)

Tuberculosis Multi Drug Resistant Active
National Cancer Institute (NCI)

Terminated

Entinostat And Imatinib Mesylate In Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Recurrent Adult Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia

United States
GlaxoSmithKline

Terminated

A First Time in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Single and Repeat Doses of GSK2485852 in Chronically Infected Hepatitis C Subjects

Hepatitis C

United States
Ahmad Tarhini
Novartis Pharmaceuticals

Terminated

Carboplatin and Etoposide Plus LBH589 for Small Cell Lung Cancer

Small Cell Lung Cancer

United States
HK inno.N Corporation

Completed

To Investigate PK and PD of CJ-12420, Clarithromycin, Amoxicillin After Multiple Dose Administration

Drug Interaction | Pharmacokinetic | Pharmacodynamic

Korea, Republic of
Damascus Hospital
UNIPHARMA. Universal Pharmaceutical Industries; Ibn Alhaytham Pharma. Industries...

Unknown

Comparison Efficacy of 14-day Triple Therapy: Clarithromycin vs. Levofloxacin on Eradication of H. Pylori

Helicobacter Pylori Gastrointestinal Tract Infection

Syrian Arab Republic
Shanghai Public Health Clinical Center

Completed

ART Drug Dosage Adjustment in HIV-infected Population

HIV Infections

China
Tibotec Pharmaceuticals, Ireland

Withdrawn

PEPI-TiDP23-C104 is a First in Human Study With a Single Dose Escalation Part and a Multiple Dosing Part for Compounds TMC589337 and TMC589354.

HIV Infections

Netherlands
London School of Hygiene and Tropical Medicine
Medical Research Council Unit, The Gambia

Terminated

Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia (SAFEPRIM-II)

Malaria

Gambia
Merck Sharp & Dohme LLC
Janssen Research & Development, LLC

Completed

Samatasvir (IDX719) in Combinations With Simeprevir and/or TMC647055/Ritonavir With or Without Ribavirin for 12 Weeks in Participants With Chronic Hepatitis C Infection (MK-1894-005)

Chronic Hepatitis C Virus
Hospital Clinic of Barcelona

Completed

Study Comparing Two Alternatives of Antiretroviral Therapy as Post-exposure Prophylaxis to HIV-1: Tenofovir + Emtricitabine + Lopinavir/Ritonavir Versus Tenofovir + Emtricitabine + Raltegravir (RAL-PEP) (RAL-PEP)

HIV Infection

Spain
International Medical Center of Japan
Ministry of Health, Labour and Welfare, Japan

Completed

Comparison of Epzicom and Truvada for the Initial Once Daily HIV Treatment

HIV Infections

Japan
Juan A. Arnaiz

Completed

Metabolic Effects of Atazanavir/Ritonavir Versus Darunavir/Ritonavir in Combination With Tenofovir/Emtricitabine in naïve HIV-1 Infected Patients

HIV-1

Spain
Boehringer Ingelheim

Completed

Exploratory Study of Tipranavir and Ritonavir in Multiple Protease Inhibitor-experienced HIV Patients

HIV Infections
Boehringer Ingelheim

Completed

Bioavailability of Dabigatran and Amiodarone After Multiple Oral Administrations of Dabigatran Etexilate With or Without Amiodarone as Single Dose in Healthy Male and Female Volunteers

Healthy
Boehringer Ingelheim

Completed

Drug Interaction Study With Rifampicin and Afatinib

Healthy

Germany
Imperial College London
Boehringer Ingelheim

Completed

The CogNaive Study: Assessing Changes in Neurocognitive Function in Treatment Naïve HIV-1 Positive Subjects

HIV Infections

United Kingdom
National Taiwan University Hospital

Unknown

Clarithromycin-based Triple Therapy for 14 Days Versus Sequential Therapy 10 Days in the First Line Therapy (THC)

Eradication Rates of the Two Regimens

Taiwan
Clatterbridge Centre for Oncology

Unknown

Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia

Lymphoma | Small Intestine Cancer | Neutropenia | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Psychosocial Effects of Cancer and Its Treatment

United Kingdom
University of California, San Francisco

Completed

Drug Interaction Study of Rifampin and Warfarin in Healthy Volunteers.

Healthy

United States
Centocor, Inc.

Completed

A Study of Safety and Effectiveness of Ustekinumab in Patients With Moderate to Severe Active Crohn's Disease Who Have Been Previously Treated With Anti-TNF Therapy

Crohn's Disease

United States, France, United Kingdom, Germany, Spain, Belgium, Israel, Australia, Canada, Netherlands, New Zealand, Austria
Vanderbilt University

Completed

Genetic Determinants of the Metabolism of Non-nucleoside Reverse Transcriptase Inhibitors

HIV Infections
European Organisation for Research and Treatment...
University of Glasgow

Completed

Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma

Lymphoma

United Kingdom
Chulalongkorn University

Unknown

The Effect of Aliskiren and Losartan on Peritoneal Membrane in Continuous Ambulatory Peritoneal Dialysis Patients

Peritoneal Membrane Failure

Thailand
Pfizer

Completed

Estimate The Effect Of Repeat-Dose Rifampin On The Pharmacokinetics Of CP-690,550 In Healthy Volunteers

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings

HIV Infections | Tuberculosis

South Africa
Fundación Huésped
Pfizer

Unknown

Maraviroc (Celsentri) With Raltegravir and Darunavir/Ritonavir for the Treatment of Triple Class Failure in Adult HIV-1 Infected Patients (TERCETO)

AIDS | HIV-1 Adults Patients | Triple Class Failure

Argentina
Peking Union Medical College
Ministry of Science and Technology of the People´s Republic of China

Completed

Three Generic Nevirapine-Based Antiretroviral Treatments in Chinese Patients:Multicentric Observation Cohort

HIV Infections

China
Boehringer Ingelheim

Completed

An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.

HIV Infections

United States
Dupont Merck

Completed

A Study of Efavirenz in Combination With Stavudine and Didanosine

HIV Infections

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Myelodysplastic Syndrome/Acute Myeloid Leukemia

United States
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
University of Aarhus
Arla Foods

Recruiting

Effects of Intact and Disrupted Milk Fat Globule Membrane on Postprandial Metabolic Response to High-fat Dairy in Healthy Individuals

Postprandial Lipid Metabolism

Denmark

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