Search clinical trials for: Tetrahydrobiopterin 10 mg/kg

Total 2026 results

U.S. Army Medical Research and Development Command
SIGA Technologies

Available

Tecovirimat Intravenous Treatment for Orthopox Virus Exposure (TPOXX IV)

Orthopox Virus Infection
GlaxoSmithKline
Hammersmith Medicines Research; Covance Harrogate

Completed

A Phase 1 Relative Bioavailability Study of Ambrisentan and Tadalfil Fixed Dose Combination Tablets in Healthy Subjects

Hypertension, Pulmonary

United Kingdom
AstraZeneca

Completed

A Study to Assess the Bioequivalence of Fixed Dose Combination of Dapagliflozin/Metformin XR Relative to Co-administration of the Individual Components in Healthy Chinese Subjects.

Healthy Volunteer

China
Hope Pharmaceuticals

Terminated

Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage

Subarachnoid Hemorrhage

United States
Emergent BioSolutions
Quintiles, Inc.; Unither Virology

Completed

Study to Determine the Safety, Tolerability and Pharmacokinetics of UV-4B Solution Administered Orally in Healthy Subjects (UV)

Viral Infection

United States
Immunic AG

Active, not recruiting

MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS) (EMPhASIS)

Relapsing-Remitting Multiple Sclerosis (RRMS)

Poland, Bulgaria, Romania, Ukraine
Butler Hospital
National Institute of Mental Health (NIMH)

Completed

Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users

Substance-Related Disorders | Depression | HIV Infections

United States
University Medical Center Groningen
Netherlands Heart Foundation

Completed

Effects of a Single Oral Dose of KETone Ester ON Exercise Performance in Patients With Chronic Heart Failure (KETONE-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction

Netherlands
Norte Study Group
Merck Sharp & Dohme LLC

Unknown

Safety and Effect of Elbasvir/Grazoprevir Combination Therapy in Hemodialysis Patients With Chronic Hepatitis C

Chronic Hepatitis C

Japan
Boehringer Ingelheim

Completed

Rt-PA in the Treatment of Acute Ischemic Stroke

Cerebrovascular Accident

Austria, Belgium, Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Italy, Netherlands, Norway, Poland, Portugal, Slovakia, Spain, Sweden, Switzerland, United Kingdom
Teva Pharmaceuticals USA

Completed

Ramipril 10 mg Capsule in Healthy Subjects Under Fed Conditions

Healthy

Canada
Swedish Orphan Biovitrum

Completed

Bioequivalence of Orfadin 20 mg Compared to Orfadin 10 mg Capsules.

Healthy

Netherlands
The Catholic University of Korea

Unknown

Neuromuscular Blockade for Optimising Surgical Conditions During Spinal Surgery

Muscle Weakness | Neuromuscular Block | Orthopedic Disorder of Spine

Korea, Republic of
University Hospital Muenster
Basilea Pharmaceutica International Ltd

Terminated

Efficacy and Safety of Oral Alitretinoin (Toctino®) in the Treatment of Patients With Cutaneous Lupus Erythematosus (AliCLE)

Lupus Erythematosus, Cutaneous

Germany
Teva Pharmaceuticals USA

Completed

Ramipril 10 mg Capsule in Healthy Subjects Under Fasting Conditions

Healthy

Canada
Teva Pharmaceuticals USA

Completed

Ramipril 10 mg Capsule in Healthy Subjects Under Fasting Conditions

Healthy

Canada
Alexza Pharmaceuticals, Inc.

Completed

Staccato Loxapine in Agitated Patients With Bipolar Disorder

Bipolar I Disorder

United States
Chong Kun Dang Pharmaceutical

Completed

To Assess the Safety, Efficacy and Tolerability of CKD-519, Administered With HMG-CoA Reductase Inhibitors

Dyslipidemias

Australia
Centocor, Inc.

Completed

A Study of the Safety and Efficacy of Ustekinumab (CNTO 1275) in Participants With Crohn's Disease

Crohn Disease

United States, Canada, Belgium
Janssen Research & Development, LLC

Completed

A Study to Examine the Pharmacokinetics, Safety and Tolerability of Multiple Oral Doses of TMC435 in Healthy Chinese Participants

Healthy

China
Xuanhan County People's Hospital

Completed

Postoperative Analgesic Effect of Esketamine

Analgesia | Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor

China
Khon Kaen University
General Drugs House Co.,LTD.; Ubon Ratchathani Cancer Hospital, Ubon Ratchathani

Completed

Topical/Oral Melatonin for Preventing Concurrent Radiochemotherapy Induced Oral Mucositis/Xerostomia Cancer Patients

Head and Neck Cancer

Thailand
Organon and Co

Completed

Retrospective Survey Evaluating the Effectiveness and Safety of Dual Inhibition Lipid-lowering in the Treatment of Dyslipidemia (Study P05171)(COMPLETED)

Dyslipidemia
University of Mississippi Medical Center
Eli Lilly and Company

Recruiting

Empagliflozin in ESKD - A Feasibility Study

Heart Failure | Kidney Failure, Chronic

United States
Human Genome Sciences Inc., a GSK Company
GlaxoSmithKline

Completed

Efficacy and Safety of Belimumab in Black Race Patients With Systemic Lupus Erythematosus (SLE) (EMBRACE)

Systemic Lupus Erythematosus

United States, South Africa, France, United Kingdom, Brazil, Colombia
The Lymphoma Academic Research Organisation
Institute of Cancer Research, United Kingdom

Recruiting

Study of Ibrutinib + CD20 Antibody and Venetoclax in Patients With Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

France, United Kingdom, Belgium
Pfizer

Completed

Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis

Ankylosing Spondylitis

Korea, Republic of, United States, Spain, Taiwan, Canada, Czech Republic, Poland, Hungary, Germany, Russian Federation
Esperion Therapeutics, Inc.

Completed

Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP) in the Breast Milk of Healthy Lactating Women

Healthy Lactating Women

United States
Dexa Medica Group

Completed

Bioequivalence Study of Two Formulations of 10 mg Lisinopril Tablet Under Fasting Condition

Healthy

Indonesia
Fujian Provincial Hospital

Completed

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Postoperative Recovery

China
Bnai Zion Medical Center
Rambam Health Care Campus

Unknown

Effects of Endothelin Receptor Antagonist on Ischemic Kidney Injury During Nephron Sparing Surgery

Kidney Failure, Acute

Israel
Ardea Biosciences, Inc.

Completed

RDEA3170 and Febuxostat Drug Interaction Study

Healthy

United States
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Completed

Efficacy and Safety Study of KN019 in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate

Rheumatoid Arthritis

China
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Sugammadex Dosed According to Actual Body Weight (ABW) or Ideal Body Weight (IBW) in Reversal of Neuromuscular Blockade (NMB) in Morbidly Obese Participants (MK-8616-146)

Neuromuscular Blockade

United States, Austria, Belgium, Denmark, Germany
Idorsia Pharmaceuticals Ltd.

Terminated

A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478

Healthy

Germany
Zogenix International Limited, Inc., a subsidiary...

Completed

A Study to Assess the Safety and Tolerability of ZX008 in Children and Young Adults With Dravet Syndrome or Lennox Gastaut Syndrome Currently Taking Cannabidiol

Dravet Syndrome | Lennox Gastaut Syndrome

United States
Shanghai Henlius Biotech

Active, not recruiting

A Clinical Trial Comparing HLX10 With Placebo Combined With Chemotherapy (Cisplatin + 5-fu) in the First-line Treatment of Locally Advanced/Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Esophageal Squamous Cell Carcinoma

China
Impax Laboratories, LLC

Completed

IPX056 in Subjects With Established Spasticity Resulting From Multiple Sclerosis

Multiple Sclerosis

United States, Canada, Estonia, Latvia, Ukraine
EMS

Recruiting

Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment

Dyslipidemia | Hypertriglyceridemia

Brazil
The Netherlands Cancer Institute
Bristol-Myers Squibb

Active, not recruiting

Study to Identify the Optimal Adjuvant Combination Scheme of Ipilimumab and Nivolumab in Melanoma Patients (OpACIN)

Stage III Skin Melanoma

Netherlands
Diskapi Teaching and Research Hospital

Not yet recruiting

Carotid Flow Time Measurement Guided Fluid Management During Spinal Anesthesia

Meniscus Disorder

Turkey
Alexza Pharmaceuticals, Inc.

Completed

Staccato Prochlorperazine in Migraine (Out Patient)

Migraine Headache | Aura

United States
Janssen Research & Development, LLC

Terminated

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-64140284 in Healthy Participants

Healthy

Belgium
Intercept Pharmaceuticals

Completed

Single Dose and Multiple Dose Trial to Assess Pharmacokinetics of Obeticholic Acid (OCA)

Healthy

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Pharmacokinetic and Safety Trial to Determine the Appropriate Dose for Pediatric Patients With Multidrug Resistant Tuberculosis

Pediatric | Multidrug Resistant Tuberculosis

Philippines, South Africa
Suzhou Zanrong Pharma Limited

Recruiting

Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors

Advanced Solid Tumors | HER2-positive Breast Cancer

China
Pharmtechnology LLC
ClinPharmInvest, LLC

Completed

Bioequivalence Study of Two Formulations of Torasemide Tablet 10 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Shire

Terminated

Evaluation of Ecallantide for Treatment of Angiotensin Converting Enzyme (ACE) Inhibitor Induced Angioedema

ACE Inhibitor Induced Angioedema

United States
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
Sandoz

Completed

To Demonstrate the Relative Bioavailability Study of Ramipril 10 mg Capsules Under Non-Fasting Conditions

Hypertension

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