Search clinical trials for: Thiotepa--escalated dose

Total 6514 results

University of Leeds

Completed

Effects of Carbohydrase-inhibiting Polyphenols on Glycaemic Response in Vivo

Hyperglycaemia

United Kingdom
Gustave Roussy, Cancer Campus, Grand Paris
LinKinVax

Recruiting

Therapeutic Vaccine in Patients With Human Papillomavirus HPV-positive Oropharyngeal Cancer (HPVDCVax)

Head and Neck Carcinoma | Adult Disease

France
Boehringer Ingelheim

Completed

A Study in Healthy People to Measure the Amount of BI 655130 in the Blood After Injecting Different Doses Into Different Parts of the Body

Healthy

Belgium
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Completed

A Phase 2a Study to Evaluate EDP-938 in the Virus Challenge Model

RSV Infection

United Kingdom
Xintian Pharmaceutical

Not yet recruiting

Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid Nodules (ESPTTN)

Thyroid Nodule

China
Sylentis, S.A.

Completed

Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops

Choroidal Neovascularization | Safety, Tolerability and Pharmacokinetic Profile in Healthy Volunteers

Spain
Gamaleya Research Institute of Epidemiology and...

Completed

Evaluation of the Safety and Immunogenicity of the Recombinant Subunit Vaccine "GamTBvac" Against the Tuberculosis. (GamTBvac)

Tuberculosis

Russian Federation
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK2339345.

Cough

United Kingdom
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Recruiting

Clinical Study to Investigate the Safety, Tolerability, and Pharmacokinetics of GR1603 in SLE

Lupus Erythematosus, Systemic

China
MedImmune LLC

Completed

Phase 1 Randomized Double-blind Placebo Controlled Study to Evaluate Safety and PK of MEDI3902 in Healthy Adults

MEDI3902 for Prevention of P. Aeruginosa Pneumonia

United States
Scripps Clinic Cancer Center
Threshold Pharmaceuticals

Unknown

TH-302 Plus Doxorubicin Delivered by Trans-Arterial Chemoembolization (TACE) in Patients With Hepatocellular Carcinoma

Hepatocellular Carcinoma

United States
Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Safety Study of NK Cells From Sibship to Treat the Recurrence of HCC After Liver Transplantation

Hepatocellular Carcinoma

China
Mitsubishi Tanabe Pharma Corporation

Completed

Safety and Immunogenicity of MT-5625 in Healthy Adults, Toddlers and Infants

Healthy

Australia, South Africa
GlaxoSmithKline

Active, not recruiting

Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection

Hepatitis B, Chronic

Taiwan, Belgium, Thailand, Germany, Spain, Hong Kong, United Kingdom, France, Poland
Serum Institute of India Pvt. Ltd.
Bill and Melinda Gates Foundation

Not yet recruiting

Clinical Study to Evaluate SIIPL qHPV Vaccine (CERVAVAC®) in Women Living With HIV Aged 15-25 Years

Human Papillomavirus Infection

Kenya, Mozambique, South Africa
Bayer

Terminated

A Study to Learn How Safe Study Drug BAY2413555 is, How it Affects the Body, and How it Moves Into, Through, and Out of the Body Over 4 Weeks of Use in Participants With Heart Failure and Implanted Cardiac Defibrillator or Cardiac Resynchronization Devices (ICD/CRT) (REMOTE-HF)

Chronic Heart Failure

United States, Spain, Denmark, Israel, Germany, Italy
Société des Produits Nestlé (SPN)

Completed

Growth, Safety and Efficacy of a Probiotic Supplement (Clara)

Probiotic Supplement

Philippines
Jeil Pharmaceutical Co., Ltd.

Unknown

Clinical Trial to Evaluate the Efficacy and Safety of JPI-289 in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke

Korea, Republic of
University of North Carolina, Chapel Hill
Naturex SA

Completed

Botanical Supplement Muscle Function and Lean Body Mass

Healthy Volunteers

United States
Glenmark Pharmaceuticals Ltd. India
Glenmark Pharmaceuticals S.A.

Withdrawn

A Clinical Trial to Study the Effects of GRC 17536 in Patients With Painful Diabetic Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients)

Painful Diabetic Neuropathy

Germany, United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.
Sanofi

Recruiting

A Study to Evaluate the Long-Term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease

Crohn Disease | Colitis, Ulcerative

United States, Hungary, Poland, Czechia, Japan, Belgium, Spain, Bulgaria, France, Italy, Slovakia, Austria
University of California, San Francisco

Not yet recruiting

Two-fraction HDR Monotherapy for Localized Prostate Cancer

Prostate Adenocarcinoma | Localized Prostate Carcinoma

United States
Anhui Provincial Hospital

Recruiting

Hypofraction Radiotherapy for Limited-Stage Small Cell Lung Cancer

Safety Issues | Efficacy, Self

China
University Hospital, Lille

Recruiting

Utility of Sodium Lactate Infusion During Septic Shock (ULIS1)

Septic Shock

France
Receptor Life Sciences

Withdrawn

Safety, Tolerability, and Efficacy of RLS103 in Subjects With Acute Anxiety Within Social Anxiety Disorder (SAD)

Social Anxiety Disorder

United States
Medical University of Warsaw

Enrolling by invitation

Induction of Sustained Unresponsiveness to Sesame Using High- and Low-dose Sesame Oral Immunotherapy

Food Allergy

Poland
Peking University Cancer Hospital & Institute

Completed

Different Radiation Dose With Concurrent Chemotherapy for Thoracic Esophageal Carcinoma

Esophageal Cancer

China
AbbVie

Completed

Study to Assess Adverse Events and Compare How Two Subcutaneous ABBV-154 Injection Formulations Move Through the Body of Adult Healthy Participants

ABBV-154

United States
Janssen Research & Development, LLC

Completed

A Study of Seltorexant (JNJ-42847922) After Single-Dose Administration in Healthy Participants

Healthy

United States
Ahon Pharmaceutical Co., Ltd.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Unknown

A Phase I Study of FCN-411 in Advanced Non-small Cell Lung Cancer Chinese Patients With EGFR Positive Mutation

Lung Cancer

China
Galapagos NV

Completed

A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in Patients With Cystic Fibrosis. (FALCON)

Cystic Fibrosis

Belgium, Bulgaria, Germany, Greece, Netherlands, Serbia, Sweden, United Kingdom
Nina la Cour Freiesleben

Completed

Individual Versus Standard Follicle Stimulating Hormone Dose for Controlled Ovarian Stimulation and Insemination

Infertility

Denmark
Affiliated Hospital of Guangdong Medical University

Not yet recruiting

Safety and Efficacy Clinical Study of Severe Hemophilia B Treatment With KL001

Hemophilia B Without Inhibitor
AIM Vaccine Co., Ltd.
Shulan (Hangzhou) Hospital; Yuncheng Central Hospital

Active, not recruiting

Clinical Trial of SARS-CoV-2 mRNA Vaccine in China

COVID-19

China
Inmunova S.A.
Hospital Italiano de Buenos Aires

Completed

Anti-Shiga Toxin Hyperimmune Equine Immunoglobulin F(ab')2 Fragment (INM004) in Healthy Volunteers

Healthy Volunteers

Argentina
Hookipa Biotech GmbH
Centre for Vaccinology Ghent - CEVAC

Completed

Trial to Evaluate Safety and Immunogenicity of a Vaccine Against HCMV

Cytomegalovirus Infection

Belgium
Vascular Pharmaceuticals, Inc.

Completed

Phase 2 Study to Evaluate Safety & Efficacy of VPI-2690B in Diabetic Nephropathy Patients

Diabetic Nephropathy

United States, Puerto Rico
Masonic Cancer Center, University of Minnesota
Center for International Blood and Marrow Transplant Research

Terminated

Donor Stem Cell Transplant in Treating Patients With Myeloid Cancer or Other Disease

Myelodysplastic Syndromes | Leukemia

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Total-Body Irradiation and Chemotherapy Followed By Donor Bone Marrow Transplant in Treating Young Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United States
University of Illinois at Chicago

Unknown

Biological Therapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Breast Cancer

Breast Cancer

United States
Mercy Medical Center

Recruiting

Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis

Hepatitis B | Cirrhosis, Liver | Chronic Liver Disease

United States
Pfizer

Completed

First-In-Human Study Of Single And Multiple Ascending Doses Of PF-06751979

Healthy Subjects

United States
Sinovac Biotech Co., Ltd

Completed

A Clinical Trial of Quadrivalent Influenza Vaccine in Children Aged 3-8 Years Old

Seasonal Influenza

China
Novartis Pharmaceuticals

Completed

Assess Bronchodilator Effect QVM149 Dosed Either in the Morning or Evening Compared to Placebo in Patients With Asthma (QVM149)

Asthma

Germany, Netherlands, United Kingdom
Royal North Shore Hospital

Recruiting

Advanced Techniques For Single-fraction Palliative Radiotherapy Versus Standard Multi Fraction Radiation (ASPIRE_Multi)

Palliative Radiotherapy

Australia
Goldman, Butterwick, Fitzpatrick and Groff
L'Oreal

Completed

Study Evaluating the Efficacy of DOSE Formulations in Treating Melasma and Cutaneous Signs of Aging

Melasma

United States
Eli Lilly and Company
AstraZeneca

Completed

A Study of Ramucirumab (LY3009806) or Necitumumab (LY3012211) Plus Osimertinib in Participants With Lung Cancer

Non-small Cell Lung Cancer

Spain, United States, Korea, Republic of, Taiwan, France
James Tarbox, MD
Texas Tech University Health Sciences Center

Recruiting

Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge

Penicillin Allergy

United States
Azura Ophthalmics
Syneos Health; Cliantha Research

Completed

A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye Disease (DED)

Dry Eye | Meibomian Gland Dysfunction

Canada, Australia, New Zealand
Eisai Inc.

Completed

Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users

Healthy | Drug Abuse

Canada

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