Search clinical trials for: Tissue plasminogen activator

Total 3538 results

Reza Behrouz, DO

Withdrawn

Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN) (TALISMAN)

Ischemic Stroke

United States
Tianjin Huanhu Hospital

Recruiting

MR Imaging Selection for Endovascular Treatment in Acute Ischemic Stroke at 6 to 24 Hours (MIELS)

Endovascular Thrombectomy

China
University Hospital, Caen

Suspended

Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. (FIVHeMA)

Subarachnoid Hemorrhage

France
Universitätsklinikum Hamburg-Eppendorf

Completed

Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke (WAKE-UP)

Stroke

Germany, United Kingdom, Belgium, Denmark, France, Spain
Centre Hospitalier Sud Francilien

Recruiting

Early Recanalization After Intravenous Thrombolysis With Tenecteplase Versus Alteplase in Distal Vessel Occlusion Strokes (DISTAL-IVT)

Acute Distal Vessel Occlusion Stroke

France
Supergene, LLC

Completed

Massive Pulmonary Embolism: Trial of Non-immunogenic Recombinant Staphylokinase VS Alteplase FORPE

Massive Pulmonary Embolism

Russian Federation
Niguarda Hospital

Completed

Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS EXP)

Stroke | Cerebrovascular Accident

Italy
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ）

Acute Ischemic Stroke

China
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Active, not recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-II）

Acute Ischemic Stroke

China
Tasly Biopharmaceuticals Co., Ltd.

Completed

Study of rhPro-UK in Patients With Acute Ischaemic Stroke in 4.5 Hours After Stroke Onset(PROST)

Acute Ischaemic Stroke

China
University of Cincinnati
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial

Stroke

United States
Chinese University of Hong Kong
Queen Mary Hospital, Hong Kong; Princess Margaret Hospital, Canada; Tuen Mun... and other collaborators

Not yet recruiting

Intravenous Thrombolytic Therapy in Acute Ischemic Stroke Patients on DOAC (DOAC-IVT)

CVA (Cerebrovascular Accident)

Hong Kong
Medical College of Wisconsin

Completed

t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection (TOPCAT)

Central Venous Catheter Thrombosis | Central Venous Catheter Associated Bloodstream Infection

United States
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai Fifth People's Hospital; Shanghai Deji... and other collaborators

Recruiting

Tenecteplase Thrombolytic Therapy for Acute Ischemic Stroke in China (TTT-AIS CHINA)

Ischemic Stroke

China
University of Melbourne
Professor Mark Parsons

Recruiting

Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion (ETERNAL-LVO)

Ischemic Stroke

Australia
Boehringer Ingelheim

Completed

A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 (TRISTARDS)

Acute Respiratory Distress Syndrome

Spain, Germany, Italy, Belgium, Mexico, Netherlands, India, France, Malaysia, Austria, Brazil, Russian Federation, Turkey
University of Melbourne

Recruiting

Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (POST-ETERNAL)

Basilar Artery Occlusion

Australia
University of Florida

Completed

Fibrinolytic Therapy Versus Medical Thoracoscopy

Pleural Diseases

United States
Centre Hospitalier Sud Francilien

Completed

Dual IntraVenous Thrombolysis Approach (DIVA) in Patients With Medium-vessel-occlusion Strokes: a Retrospective Study (DIVArétro)

Acute Ischemic Stroke Due to Medium-vessel-occlusion

France
Chiesi Farmaceutici S.p.A.

Terminated

Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality (READY 1)

Thrombosis | Catheter Occlusion

United States, Argentina, Belgium, Czechia, Poland, Romania, Spain
Northwestern University

Suspended

Study To antagOnize Plasminogen Activator Inhibitor-1 in Severe COVID-19

Covid19

United States
University of Medicine and Pharmacy at Ho Chi Minh...

Unknown

Efficacy of Intravenous Tissue-type Plasminogen Activator on Acute Ischemic Stroke Patients With Large Vessel Occlusions

Stroke, Ischemic | Stroke, Acute

Vietnam
Erasmus Medical Center
DUMAS is sponsored by an unrestricted grant from Thrombolytic Science International...

Completed

Dual Thrombolytic Therapy With Mutant Pro-urokinase and Low Dose Alteplase for Ischemic Stroke (DUMAS)

Ischemic Stroke

Netherlands
RenJi Hospital

Completed

EARLY Routine Catheterization After Alteplase Fibrinolysis vs. PPCI in ST-Segment-Elevation MYOcardial Infarction (EARLY-MYO)

Acute ST-segment Elevation Myocardial Infarction

China
Central Hospital, Nancy, France

Terminated

Trial and Cost Effectiveness Evaluation of Intra-arterial Thrombectomy in Acute Ischemic Stroke (THRACE)

Cerebrovascular Accident | Cerebral Stroke

France
University of California, San Diego
National Institute of Neurological Disorders and Stroke (NINDS); Scripps Health

Withdrawn

Study for the Use of Alteplase in Patients Who Awaken With Stroke (AWOKE)

Ischemic Stroke

United States
Ahi Evren Chest and Cardiovascular Surgery Education...

Unknown

Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism

Pulmonary Embolism

Turkey
Tasly Biopharmaceuticals Co., Ltd.

Completed

A Trial in Recombinant Human Prourokinase to Treat Acute Pulmonary Embolism (ERUPTE)

Acute Pulmonary Embolism

China
University of Thessaly

Completed

Assessment of the Soluble Urokinase Plasminogen Activator Receptor in Non-cardiac Surgery (SPARSE) (SPARSE)

Surgery--Complications

Greece
University of Manitoba
Hoffmann-La Roche

Terminated

Alteplase for Blood Flow Restoration in Hemodialysis Catheters

Thrombosis

Canada
Daniel Hanley
National Institute of Neurological Disorders and Stroke (NINDS); Genentech,... and other collaborators

Completed

Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation (MISTIE)

Intracerebral Hemorrhage

United States, Germany, United Kingdom, Canada
University of Thessaly

Completed

SuPAR in Adult Patients With Covid-19 (SPARCOL)

Covid19

Greece
Boehringer Ingelheim

Completed

Temporal Trends of Thrombolysis Treatment in Chinese Acute Ischemic Stroke (AIS) Patients From 2007-2017: Analysis of China National Stroke Registry (CNSR) I, II, and III; CTP-Draft Review Performed;

Stroke

China
Global Biotech

Completed

Safety Study of a Recombinant Human Plasminogen Activator to Treat Acute Ischemic Stroke.

Cerebrovascular Accident

Taiwan
Xinqiao Hospital of Chongqing
Zhejiang University

Recruiting

Intravenous Tirofiban Versus Alteplase Before Mechanical Thrombectomy in Stroke (ADJUVANT)

Stroke, Acute Ischemic

China
University Health Network, Toronto

Withdrawn

Study of Sodium Bicarbonate in Restoring Blocked Catheters

Cancer | Central Venous Catheterization

Canada
Joseph Broderick
Medical University of South Carolina; National Institute of Neurological Disorders... and other collaborators

Terminated

Interventional Management of Stroke (IMS) III Trial (IMSIII)

Stroke

Canada, United States, Switzerland, Germany, Spain, Netherlands, Australia, France
Second Affiliated Hospital of Nanchang University
Changhai Hospital

Recruiting

Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)

Aneurysmal Subarachnoid Hemorrhage

China
Denver Health and Hospital Authority
University of Colorado, Denver; University of Miami; Beth Israel Deaconess Medical... and other collaborators

Completed

Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection

Severe Acute Respiratory Syndrome | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
Larissa University Hospital

Recruiting

The Role of Ischemia Modified Albumin in Patients With COVID-19

COVID-19

Greece
Fondation Ophtalmologique Adolphe de Rothschild

Terminated

Embolectomy in Acute SYlvian Thrombosis in Refractory or Ineligible Patients to ALteplase (EASY)

Stroke, Acute

France
Rigshospitalet, Denmark
University Hospital Bispebjerg and Frederiksberg; Hillerod Hospital, Denmark; Herlev and Gentofte Hospital and other collaborators

Recruiting

Low Dose Thrombolysis, Ultrasound Assisted Thrombolysis or Heparin for Intermediate High Risk Pulmonary Embolism (STRATIFY)

Pulmonary Embolism

Denmark
AirXpanders, Inc.

Completed

Patient Controlled Tissue Expansion for Breast Reconstruction (XPAND)

Breast Cancer

United States
Northwell Health

Completed

Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE

Thromboembolism | Pulmonary Hypertension | Pulmonary Embolism | Right Ventricular Dysfunction

United States
Poitiers University Hospital

Completed

Prognostic Value of Soluble Urokinase Plasminogen Activation Receptor (SUPAR) to Rule Out Complications in Patients Admitted in Emergency Department for Acute Abdominal Pain. (GRADIENT)

Mortality | Abdominal Pain | Emergency Department | Soluble Urokinase Plasminogen Activation Receptor

France
Beijing Tiantan Hospital

Recruiting

Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5 (TRACE-5)

Ischemic Stroke, Acute

China
GrandPharma (China) Co., Ltd.

Active, not recruiting

A Study Evaluating the Safety and Efficacy of Tirofiban in Combination With Alteplase in Acute Ischemic Stroke (RESET)

Acute Ischemic Stroke

China
Jacobs Neurological Institute
Genentech, Inc.; University at Buffalo Neurosurgery

Unknown

Wake up Symptomatic Stroke - Benefit of Intravenous Clot Busters or Endovascular Intervention (WASSABI)

Stroke

United States
Bastyr University
University of Washington

Completed

Feeding the Rainbow to Investigate Endothelial Dysfunction (FRIED)

Cardiovascular Disease | Dietary Modification

United States
University Hospital, Basel, Switzerland
University Hospital Freiburg; Istituto Ortopedico Galeazzi; General Hospital... and other collaborators

Completed

Clinical Trial for the Regeneration of Cartilage Lesions in the Knee (NosetoKnee2)

Tear; Knee, Cartilage, Articular

Switzerland, Germany, Croatia, Italy

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