Search clinical trials for: Tissue plasminogen activator

Total 3557 results

AstraZeneca

Completed

Dose-finding Study Comparing Efficacy and Safety of a PARP Inhibitor Against Doxil in BRCA+ve Advanced Ovarian Cancer (ICEBERG 3)

Ovarian Neoplasms

Spain, United States, Belgium, United Kingdom, Israel, Poland, Germany, Sweden, Australia
Endocyte

Completed

Platinum Resistant Ovarian Cancer Evaluation of Doxil and Vintafolide (MK-8109, EC145) Combination Therapy (8109-009, EC-FV-04) (PRECEDENT)

Ovarian Cancer
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Treated T Cells Followed by a Stem Cell Transplant in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
Fudan University

Unknown

Preoperative Transhepatic Arterial Chemotherapy (TAC) in the Treatment of Liver Metastasis of Resectable Colorectal Cancer

Colorectal Cancer

China
University of Regina
Saskatchewan Health Research Foundation; Saskatchewan Centre for Patient-Oriented... and other collaborators

Completed

Internet-delivered Therapy for Alcohol Misuse: Factorial Trial of Assessment and Guidance

Alcohol Misuse

Canada
Faculty Sao Leopoldo Mandic Campinas

Completed

Efficacy of Sealants in Cavitated Enamel Lesions on Occlusal Surfaces in Children (SLM1661)

Fissure Sealants | Oral Hygiene Orientation

Brazil
Sun Yat-sen University
First People's Hospital of Foshan; Guangzhou No.12 People's Hospital

Recruiting

HAIC With One-day FOLFOX vs. HAIC With Two-day FOLFOX for Unresectable HCC: a Non-inferiority Study

Hepatocellular Carcinoma

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Activated White Blood Cells With ASCT for Newly Diagnosed Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
CSL Behring

Completed

Human C1 Esterase Inhibitor (C1-INH) in Subjects With Acute Abdominal or Facial Hereditary Angioedema (HAE) Attacks

Hereditary Angioedema

Bulgaria, United States, Poland, Spain, Hungary, United Kingdom, Russian Federation, Macedonia, The Former Yugoslav Republic of, Argentina, Australia, Canada, Czech Republic, Israel, Romania, Sweden
Western Galilee Hospital-Nahariya

Unknown

Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes

Premature Rupture of Membrane

Israel
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety Study of OPC-12759 Ophthalmic Solution

Dry Eye Syndromes

Japan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Evaluation of Viral Replication by Tonate Virus (TONV) and Zika Virus (ZIKV), Within an ex Vivo Trophoblast and Placental Model (ZITOPEx)

Zika Virus Infection
Lawrence Fong
Genentech, Inc.

Recruiting

Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

Prostate Cancer | Prostate Adenocarcinoma | Localized Prostate Cancer

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Terminated

Serum-Free Thymus Transplantation in DiGeorge Anomaly (SerumFree)

DiGeorge Anomaly
Federal University of Juiz de Fora

Unknown

Evaluation of Bone Quality and Primary and Secondary Stability of Implants Installed in Alveolar Regeneration Area by Three Different Techniques

Alveolar Osseous Loss

Brazil
Arbeitsgemeinschaft medikamentoese Tumortherapie
AOP Orphan Pharmaceuticals AG

Completed

Addition of P1101 to Imatinib Treatment in Patients With Chronic Phase Chronic Myeloid Leukaemia Not Achieving a Complete Molecular Response

Chronic Phase Chronic Myeloid Leukemia

Austria
Jinling Hospital, China

Unknown

Tissue Kallikrein Preventing the Restenosis After Stenting of Symptomatic MCA Atherosclerotic Stenosis

Cerebrovascular Disease

China
Torrent Pharmaceuticals Limited

Completed

Bioequivalence Study of Torrent Pharmaceutical Limited's ISMN 120 mg ER Tablets Under Fasting Condition

Healthy

India
Medical University Innsbruck
Charite University, Berlin, Germany; University Hospital, Ghent; University of... and other collaborators

Completed

Histidine-Tryptophane-Ketoglutarate (HTK) vs University of Wisconsin (UW) Perfusion in Clinical Pancreas Transplantation

Diabetes Mellitus | Pancreas Transplantation

Austria, Belgium, Germany
National Institute of Diabetes and Digestive and...

Withdrawn

Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B

Chronic Hepatitis B

United States
National Taiwan University Hospital

Completed

Interferon Treatment for Patients With Chronic Hepatitis C and End Stage Renal Disease

End Stage Renal Disease | Chronic Hepatitis C

Taiwan
Mayo Clinic

Recruiting

Genetically Engineered Cells (MUC1-Activated T-Cells) for the Treatment of MUC1 Positive Recurrent or Refractory Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States
University Hospital, Basel, Switzerland
Pharming Technologies B.V.; Clinical Trial Unit, University Hospital Basel,...

Completed

Recombinant Human C1 Esterase Inhibitor in the Prevention of Contrast-induced Nephropathy in High-risk Subjects (PROTECT)

Acute Kidney Injury

Switzerland
University of Southern California
Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA

Completed

Trial of Liposomal Doxorubicin (Doxil) and Weekly Docetaxel (Taxotere)

Carcinoma | Cancer

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Biological Therapy and Gene Therapy in Treating Children With Recurrent or Refractory Neuroblastoma

Neuroblastoma

United States
Fudan University

Completed

Postoperative Folfox4 Only Versus Folfox4 Plus Transhepatic Arterial Chemotherapy (TAC) in the Treatment Unresectable Liver Metastasis of Colorectal Cancer

Unresectable Liver Metastasis of Colorectal Cancer

China
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy (SOTA-CROSS HCM)

Hypertrophic Cardiomyopathy Without Obstruction
University Medical Center Groningen

Terminated

IL2 Imaging in Metastatic Melanoma

Melanoma

Netherlands
AdventHealth Translational Research Institute

Active, not recruiting

Measurement of NAD+ Synthesis in Human Skeletal Muscle (NAD-flux)

Skeletal Muscle

United States
Washington University School of Medicine
University of Malawi

Completed

Combined Package of Interventions for Environmental Enteropathy

Environmental Enteropathy

Malawi
Casa Sollievo della Sofferenza IRCCS

Completed

Efficacy Study of New Therapeutic Schedules in Naive Hepatitis C Virus (HCV) Patients Infected With Genotype 3 (HCV-3) (genotype-3)

Chronic Hepatitis

Italy
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Levofloxacin Compared With Amoxicillin/Clavulanate Potassium in the Treatment of Adults With Rapid Onset of Severe Inflammation/Infection of the Sinuses

Sinusitis | Maxillary Sinusitis
University of Oxford
National Institute for Health Research, United Kingdom

Completed

Combined Antidepressant and Behavioural Intervention (CABIN)

Depression | Anxiety | Low Mood

United Kingdom
Brock Liden, DPM

Withdrawn

Activated Carbon Interphase Effect on Surgical Incisions vs.Two Common Wound Dressings

Surgical Wound, Healed

United States
Consorzio Oncotech

Completed

Liquid Biopsy: Intercepting Mutational Trajectories of HER2 (Human Epidermal Growth Factor Receptor 2) Breast Cancer (GIM21 Trial) (GIM21)

Metastatic Breast Cancer

Italy
GlySure
Kentron

Unknown

Comparative Study of GlySure Continuous Intra-vascular Glucose Monitoring and Intermittent Monitoring in Medical ICU (MICU)

Blood Glucose Monitoring in Medical ICU
Benaroya Research Institute
University of California, San Diego

Completed

Immune Effects of Vedolizumab With or Without Anti-TNF Pre-treatment in T1D (COBRA)

Type 1 Diabetes

United States
University of Texas, El Paso
University of California, San Francisco; Centro de Integracion Juvenil; El Centro...

Active, not recruiting

Optimizing a Bio-behavioral Intervention for Sustained Viral Suppression

HIV Viremia

Mexico
CSL Behring

Completed

A Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema

Hereditary Angioedema Types I and II

United States, Spain, Australia, Canada, Czechia, Hungary, Israel, Italy, Romania, United Kingdom
Centre Hospitalier Universitaire de Saint Etienne

Completed

Effect of Activated Charcoal on Rivaroxaban Pharmacokinetics in Healthy Subjects (RICHAR)

Healthy

France
Dana-Farber Cancer Institute
Eli Lilly and Company

Active, not recruiting

A Phase II Study of Ramucirumab With Somatostatin Analog Therapy in Patients With Advanced, Progressive Carcinoid Tumors

Carcinoid Tumors

United States
EMD Serono Research & Development Institute, Inc.

Completed

A Phase 2 Study of Cladribine Add-on to Interferon-beta (IFN-beta) Therapy in Multiple Sclerosis (MS) Subjects With Active Disease (ONWARD) (ONWARD)

Multiple Sclerosis

United States, Italy, Russian Federation, Spain
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Effectiveness of N-Acetylcysteine (NAC) in Treating Cocaine Dependent Individuals - 1 (NAC)

Cocaine Dependence

United States
Genzyme, a Sanofi Company
Bayer

Completed

Comparison of Alemtuzumab and Rebif® Efficacy in Multiple Sclerosis, Study Two (CARE-MS II)

Multiple Sclerosis, Relapsing-Remitting

Australia, Denmark, Canada, United States, Netherlands, Argentina, Austria, Belgium, Brazil, Croatia, Czech Republic, France, Germany, Israel, Italy, Mexico, Poland, Russian Federation, Serbia, Spain, Sweden, Ukraine, United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Adults With Uncomplicated Infections of the Skin and the Supportive Layers Beneath the Skin

Skin Diseases, Infectious
National Taiwan University Hospital
National Science Council, Taiwan; Department of Health, Executive Yuan, R.O...

Completed

Retreatment of Dialysis Patients With Chronic Hepatitis C With Pegylated Interferon Alfa-2a Plus Low Dose Ribavirin

Hemodialysis | Chronic Hepatitis C

Taiwan
Charite University, Berlin, Germany

Unknown

Trial of Levofloxacin as Prophylaxis After Allogeneic Stem Cell Transplantation (SCT)

Allogeneic Stem Cell Transplantation | Malignancy

Germany
Bristol-Myers Squibb
Eli Lilly and Company; Clovis Oncology, Inc.; Exelixis

Withdrawn

A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy (CheckMate 79X)

Carcinoma, Non-small Cell Lung Cancer

Netherlands, Norway, Belgium, Greece, United States, Argentina, Denmark, Mexico, Poland, Romania
Kocaeli University

Completed

The Incidence of Thoracic Disc Herniation in Patients Presenting With Chronic Upper Back Pain

Thoracic Disc Herniation

Turkey
University Hospital, Tours

Completed

Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote)

Treatment Resistant Depression | Nitrous Oxyde

France

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