Search clinical trials for: tofacitinib modified-release (MR) formulation

Total 202 results

LEO Pharma

Completed

A Trial to Investigate the Safety, Tolerability, and Drug Levels in Blood After Single and Multiple Doses of LEO 32731 in Healthy People

Healthy

United Kingdom
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Compare the Actions in the Body of Healthy Subjects of Three Modified Release Formulations of YM178 Under Fasted and Fed Conditions With One Immediate Release Formulation of YM178 Under Fasted Conditions

Healthy Subjects | Pharmacokinetics of YM178

Netherlands
Astellas Pharma Inc

Completed

Comparison of Plasma Concentration Changes Between Two Types of Tablets of FK949E Administration to Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Astellas Pharma Inc

Completed

Study to Evaluate the Effect of Food Intake on the Plasma Concentration Changes of Quetiapine After Oral Administration of FK949E in Healthy Volunteers

Healthy | Plasma Concentration Change of Quetiapine

Japan
Astellas Pharma Inc

Completed

Study to Evaluate Safety and Tolerability of FK949E in Elderly Patients With Major Depressive Disorder

Major Depressive Disorder Patients

Japan
Astellas Pharma Inc

Completed

Study to Evaluate Safety and Tolerability of FK949E in Patients With Major Depressive Disorder

Major Depressive Disorder Patients

Japan
University Hospital, Angers
Alfediam; UNIVALOIRE

Unknown

Microvascular Response in Diabetes Mellitus

Diabetes Mellitus

France
Massachusetts General Hospital

Completed

Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD

Autism Spectrum Disorder | Attention-deficit/Hyperactivity Disorder

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Flavopiridol in Treating Patients With Recurrent or Persistent Endometrial Cancer

Endometrial Cancer

United States, Canada, Norway, United Kingdom, Australia
Astellas Pharma Inc

Completed

Oral Multiple-dose Study in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Takeda

Completed

A Study to Evaluate the Pharmacokinetics of Dexlansoprazole 30 Milligram (mg) and 60 mg Delayed-release Capsules in Healthy Chinese Participants

Healthy Volunteers

China
Astellas Pharma Inc

Completed

A Study to Demonstrate Safety and Efficacy of Advagraf in Patients Undergoing Kidney or Liver Transplantation in India

Liver Transplantation | Kidney Transplantation

India
Clinical Testing of Beverly Hills
Galderma R&D

Active, not recruiting

Dysport Dose-Ranging Treatment of Platysmal Bands

Platysma Bands

United States
ApoPharma
Algorithme Pharma Inc

Completed

Comparison of Deferiprone Delayed Release Tablets and Deferiprone Oral Solution in Healthy Volunteers

Healthy

Canada
Novartis Pharmaceuticals

Completed

Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months), in Renal Transplant Patients

Kidney Transplantation

France, Germany, United Kingdom, Spain, Switzerland, United States, Canada, Italy
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate the Effect of Advagraf Conversion From Prograf in Liver Transplant Subjects (Maple)

de Novo Liver Transplant Subjects

Korea, Republic of
Janssen Sciences Ireland UC

Completed

Relative Bioavailability of Three Oral Formulations Candidates of Rilpivirine for Potential Pediatric Use Compared to Oral Tablet

Healthy

Belgium
Mundipharma Korea Ltd

Completed

Efficacy of Lodotra®(Prednisone) in Reduction of Morning Stiffness Duration(K-IMPROvE)

Rheumatoid Arthritis

Korea, Republic of
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

A Study to Assess the Safety and Efficacy of Prograf and MR4 in Kidney Transplantation Patients

Kidney Transplantation

Korea, Republic of
Faculdade de Ciências Médicas da Santa Casa de...

Completed

The Treatment of Shoulder Pain in Hemiplegic Spastic Patients With Botulinum Toxin A (dolomtox)

Shoulder Pain

Brazil
Astellas Pharma Korea, Inc.

Completed

A Single Center, Open-label, Randomized, Pilot Study to Evaluate the Safety and Efficacy of a Tacrolimus Modified Release, ADVAGRAF®, Versus Tacrolimus Twice Daily, PROGRAF® in Stable Renal Recipients (SINGLE)

Kidney Transplantation | Renal Transplantation | Stable Renal Recipients

Korea, Republic of
Astellas Pharma Inc

Completed

An Open Study Assessing Bioavailability of a Modified Formulation of Tacrolimus in Kidney Transplant Recipients

Kidney Transplantation

Netherlands
Cosmo Technologies Ltd

Completed

The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy

Colorectal Cancer

United States, Belgium, Canada, Germany, Italy, Lithuania, Netherlands, United Kingdom
Astellas Pharma Inc

Completed

A Study to Assess the Pharmacokinetics, Safety and Efficacy of Advagraf and Prograf in de Novo Liver Transplantation (MAIN)

Liver Transplantation

Korea, Republic of
Tampere University Hospital
Helsinki University Central Hospital; Oulu University Hospital

Completed

Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour

Labour Induction

Finland
Amgen

Completed

Phase 1b Study Evaluating OPomD in Relapsed or Refractory Multiple Myeloma (INTREPID-1)

Relapsed or Refractory Multiple Myeloma

United States, Belgium, Australia, Spain, Canada, Netherlands
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

A Study to Assess the Safety and Efficacy of Prograf and MR4 in Liver Transplant Recipients

Liver Transplantation

Korea, Republic of
Corino Therapeutics, Inc.
Quotient Sciences

Completed

A Study Assessing the Safety and Pharmacokinetic Profile of Modified Release Formulations of Tolcapone

Healthy Volunteers

United Kingdom
Astellas Pharma Inc

Completed

Study to Compare the Pharmacokinetics of Tacrolimus in Adult Transplant Recipients Treated With Advagraf® or Prograf®

Heart Transplantation | Lung Transplantation | Pancreas (Including SPK) Transplantation

France, United Kingdom, Taiwan, Belgium, Italy, Austria
Astellas Pharma Inc

Completed

Comparative Study of Modified Release (MR) Tacrolimus/Mycophenolate Mofetil (MMF) in de Novo Kidney Transplant Recipients

Kidney Transplantation

United States, Canada, Brazil
Minneapolis Veterans Affairs Medical Center
United States Department of Defense

Completed

Gulf War Illness Inflammation Reduction Trial (GWIIRT)

Fatigue | Chronic Pain | Cognitive Impairment | Chronic Inflammation

United States
Abbott

Completed

A Study of Leuprolide to Treat Prostate Cancer

Prostate Cancer

United States
Nanexa AB
Profil Institut für Stoffwechselforschung GmbH

Not yet recruiting

Phase 1 Study Assessing the Pharmacokinetics of NEX-22A in Subjects With T2D

Type 2 Diabetes
ViiV Healthcare
GlaxoSmithKline

Completed

Bioequivalence Study of Fixed Dose Versus Single Entities of Dolutegravir and Lamivudine

Infection, Human Immunodeficiency Virus

United States
Astellas Pharma Inc

Completed

A Study to Evaluate and Compare the Efficacy and Safety of FK506MR vs Prograf® in Stable Liver Transplantation Patients

Liver Transplantation

China
Abbott

Completed

Outcome Study to Evaluate Klaricid XL® (Clarithromycin Modified Release) in Patients With Acute Exacerbation of Chronic Bronchitis

Bronchitis

Pakistan
Diurnal Limited
Simbec Research

Completed

Effect of Slow Release Hydrocortisone on Fed & Fasting Volunteers; Immediate Release on Fasting Only

Healthy
Veloxis Pharmaceuticals
PPD

Completed

Safety and Efficacy of LCP-Tacro™ Once Daily in Stable Renal Transplant Patients Converted From Prograf® Twice Daily

Renal Failure

United States
GlaxoSmithKline

Completed

The CLEVER Study - Coreg And Left Ventricular Mass Regression

Hypertrophy, Left Ventricular

United States
AstraZeneca
Bristol-Myers Squibb

Completed

Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes

Type 2 Diabetes Mellitus

Korea, Republic of, United States, Mexico, India, Puerto Rico, Russian Federation
Duke University

Completed

Effect of Bupropion on Seizure Threshold in Depressed Patients

MDD

United States
Tocagen Inc.

Withdrawn

A Study of Toca 511 & Toca FC in Patients With Recurrent High Grade Non-Muscle Invasive Bladder Cancer (Toca 8)

Bladder Cancer
University of Valencia

Completed

Clinical Study of Raloxifene and Strontium Ranelate in Postmenopausal Osteoporosis

Postmenopausal Osteoporosis | Compliance

Spain
Ian McGowan
National Institute of Allergy and Infectious Diseases (NIAID); CONRAD

Completed

An Exploratory Rectal Safety Study of Three Tenofovir Gel Formulations

HIV Prevention

United States
GlaxoSmithKline

Completed

COREG MR Versus TOPROL-XL On The Lipid Profile Of Normolipidemic Or Mildly Dyslipidemic Patients With Hypertension

Hypertension

United States, Canada, Puerto Rico
Shire

Completed

Once-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency

Adrenal Insufficiency
National Cancer Institute (NCI)

Completed

Bortezomib and Flavopiridol in Treating Patients With Recurrent or Refractory Indolent B-Cell Neoplasms

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma and other conditions

United States
Astellas Pharma Inc

Completed

A Study to Compare the Efficacy and Safety of FK506MR vs Prograf® in Patients Undergoing Liver Transplantation

Liver Transplantation

China
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Alcohol Pharmacotherapy for HIV+ Prisoners (INSPIRE)

Alcohol Dependence | Human Immunodeficiency Virus | AIDS | Hazardous Drinking | Problem Drinking

United States

Search clinical trials for: tofacitinib modified-release (MR) formulation

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