Search clinical trials for: topotecan hydrochloride

Total 7633 results

Michael Vogelbaum, MD, PhD
Infuseon Therapeutics, Inc.

Completed

Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma

Malignant Glioma | WHO Grade III or IV Recurrent Glioma

United States
First Hospitals affiliated to the China PLA General...

Unknown

Topotecan Plus Apatinib Versus Topotecan Alone as Second-line Therapy in Small-cell Lung Cancer

Small Cell Lung Cancer
Daiichi Sankyo Co., Ltd.

Completed

An Observational Study of CPT-11 Plus Platinum Analogues Regimens and UGT1A1 Genotypes in Solid Tumors

Cervical Cancer | Small Cell Lung Cancer | Ovarian Cancer | Non-small Cell Lung Cancer | Gastric Cancer (Inoperable and Recurrent)

Japan
PharmaMar

Recruiting

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Relapsed Small Cell Lung Cancer

United States, Spain, Japan, Korea, Republic of, United Kingdom, Israel, France, Taiwan, Germany, Australia, Belgium, Georgia, Italy, Switzerland, Denmark, Hungary, Poland, Romania, Canada, Brazil, Bulgaria, Austria, Chile, Turkey
Celgene Corporation

Completed

Study Comparing Amrubicin Versus Topotecan in Patients With Small Cell Lung Cancer Who Have Responded to Prior Therapy.

Small Cell Lung Cancer

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Bromhexine Given as Granules and Syrup in Healthy Volunteers (Clinical Phase I Study)

Healthy

Germany
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Multiple Therapies in Treating Patients With Advanced Neuroblastoma

Neuroblastoma

United States
Actuate Therapeutics Inc.

Recruiting

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Neuroblastoma | Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Refractory Cancer | Refractory Neoplasm | Refractory Tumor | Cancer Pediatric | Neuroblastoma Recurrent | Pediatric Lymphoma | Pediatric Meningioma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Ewing Sarcoma of Bone | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Drexel University College of Medicine

Completed

Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Thrombocytopenia

United States
Institut Curie
Fondation Rothschild Paris

Recruiting

Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome (RETINO2018)

Retinoblastoma

France
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Phase III Extended Clinical Trial of Jaktinib Hydrochloride Tablets in the Treatment of Moderate and Severe Atopic Dermatitis

Atopic Dermatitis

China
Jiangxi Provincial Cancer Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients (ALTER-E005)

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms by Histologic Type | Neoplasms by Site | Gastrointestinal Neoplasms | Digestive System Neoplasms | Carcinoma, Squamous Cell | Esophageal Neoplasms | Esophageal Diseases | Neoplasms, Squamous Cell | Esophageal Squamous Cell Carcinoma

China
First People's Hospital of Hangzhou
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Study of Anlotinib in the Treatment of Recurrent High-grade Glioma

Recurrent High-grade Glioma

China
Zhejiang Huahai Pharmaceutical Co., Ltd.

Completed

To Explore the Safety and Efficacy of Hypidone Hydrochloride Tablets in Treatment of Patients With MDD

Major Depressive Disorder

China
Peng Yuan

Completed

Anlotinib in Metastatic HER2 Negative Breast Cancer

Breast Neoplasm | Antineoplastic Agents | Anlotinib

China
Shanghai Jiao Tong University School of Medicine

Completed

Study of Berberine Hydrochloride in Prevention of Colorectal Adenomas Recurrence

Colorectal Adenoma

China
Jiangsu Simcere Pharmaceutical Co., Ltd.

Completed

Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of Simotinib Hydrochloride in Healthy Subjects

Healthy

China
Zheng Liu
National Natural Science Foundation of China

Not yet recruiting

Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis

Allergic Rhinitis

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Phase III Study of Jaktinib in Adults With Moderate and Severe Atopic Dermatitis

Atopic Dermatitis

China
Sun Yat-sen University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Anlotinib Maintenance Treatment for Advanced Soft Tissue Sarcoma

Soft Tissue Sarcoma

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Study of Jaktinib In Patients With Myelofibrosis Who Were Relapsed or Refractory of Ruxolitinib Treatment.

Myelofibrosis

China
Yuhong Li

Completed

Study of Icotinib Hydrochloride in Treating Patients With Recurrent or Metastatic Esophageal Cancer After Failure of Conventional Chemotherapy

Esophageal Squamous Cell Carcinoma

China
Kubota Vision Inc.

Completed

Pharmacodynamic Study of Emixustat Hydrochloride in Subjects With Macular Atrophy Secondary to Stargardt Disease

Stargardt Disease | Macular Atrophy

United States
Changzhou Cancer Hospital of Soochow University

Unknown

Anlotinib Combined With Sintilimab as Second-line Treatment or Beyond in Patients With Small Cell Lung Cancer

Small Cell Lung Cancer

China
First Hospital of Shijiazhuang City

Unknown

Efficacy and Safety of Anlotinib as Maintenance Treatment After First-line Chemotherapy in SCLC

Carcinoma | Small Cell Lung Cancer | Lung Neoplasm

China
Tianjin Anding Hospital

Completed

Berberine Treat Metabolic Syndrome in Schizophrenia

Schizophrenia | Metabolic Syndrome | Female

China
Eisai Inc.

Completed

A Single Dose Pharmacokinetic Study of Lorcaserin Hydrochloride in Obese Pediatric Subjects 6 to 11 Years of Age

Obesity

United States
Janssen Research & Development, LLC
Cegedim Strategic Data

Completed

PRILIGY Usage Patterns in Selected Populations

Sexual Dysfunction, Physiological
M.D. Anderson Cancer Center
GlaxoSmithKline

Withdrawn

Phase II Study of Pazopanib and Topotecan in Cervical Cancer

Cervical Cancer
Guangdong Association of Clinical Trials
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Anlotinib Hydrochloride Combined With EGFR-Tyrosine Kinase Inhibitor (TKI) in Treating Advanced NSCLC Patients With Acquired Resistance to EGFR-TKI

NSCLC

China
Boehringer Ingelheim

Completed

Relative Bioavailability of Ambroxol Hydrochloride of Soft Pastilles Compared to Ambroxol Hydrochloride Syrup in Healthy Male and Female Volunteers

Healthy
Luye Pharma Group Ltd.

Recruiting

A Study to Evaluate Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets in Generalized Anxiety Disorder.

Generalized Anxiety Disorder

China
Peking University First Hospital
Peking University Hospital of Stomatology

Completed

Penehyclidine and Postoperative Nausea and Vomiting After Bimaxillary Surgery

Postoperative Nausea and Vomiting | Penehyclidine | Bimaxillar Surgery

China
Abbott

Recruiting

Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia

Functional Dyspepsia

Malaysia, Armenia
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal or Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions
MEI Pharma, Inc.
SCRI Development Innovations, LLC

Terminated

ME-344 Given in Combination With Hycamtin® in Patients With Solid Tumors

Solid Tumors

United States, United Kingdom
National Center for Research Resources (NCRR)

Unknown

Study of the Farnesyl Transferase Inhibitor, R115777, in Combination With Topotecan (NYU 99-32)

Cancer

United States
GC Biopharma Corp

Recruiting

A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fasting Conditions

Healthy Volunteers

Korea, Republic of
National Cancer Institute (NCI)

Active, not recruiting

Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers

Uterine Cervical Neoplasms | Small Cell Lung Carcinoma | Ovarian Neoplasms | Carcinoma, Neuroendocrine | Extrapulmonary Small Cell Cancer | Carcinoma, Non-Small -Cell Lung

United States
Daniela Matei, MD
Bayer; Hoosier Cancer Research Network

Terminated

Sorafenib + Topotecan for Platinum-Resistant Recurrent Ovarian Cancer

Ovarian Cancer

United States
University of New Mexico

Completed

Study of Adjuvant Topotecan and Cisplatin With Concurrent Radiation Therapy for Advanced Cervical Cancer

Cervical Cancer

United States
Hoffmann-La Roche

Completed

Pertuzumab in Platinum-Resistant Low Human Epidermal Growth Factor Receptor 3 (HER3) Messenger Ribonucleic Acid (mRNA) Epithelial Ovarian Cancer (PENELOPE)

Ovarian Cancer

Italy, Austria, Belgium, France, Germany, Spain, Netherlands, Sweden, Denmark, Norway
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

A Study of Jaktinib for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease.

Acute Graft-Versus-Host Disease

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Comparative Study on Pharmacokinetics of Two Formulations of Jaktinib in Healthy Adults Under Fasting Conditions

Myelofibrosis

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Pharmacokinetics Of Jaktinib In Subjects With Hepatic Impairment And Normal Hepatic Function

Hepatic Insufficiency | Healthy Subjects

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Jaktinib for the Treatment of Ruxolitinib Intolerance of Myelofibrosis

Primary Myelofibrosis (PMF) | Post-polycythemia Vera Myelofibrosis(Post-PV MF) | Post-essential Thrombocythemia Myelofibrosis(Post-ET MF)

China
Haisco Pharmaceutical Group Co., Ltd.

Completed

Study of Acetyllevocarnitine Hydrochloride Tablets in Chinese Patients With Paresthesias Caused by DPN

Paresthesia | Diabetic Peripheral Neuropathy (DPN)

China
Zhejiang Huahai Pharmaceutical Co., Ltd.

Completed

Study to Explore the Effective Doses and to Assess the Safety and Efficacy of Hypidone Hydrochloride Tablets

Major Depressive Disorder

China
Sihuan Pharmaceutical Holdings Group Ltd.

Completed

Levo Phencynonate Hydrochloride for the Prevention of Seasickness

Motion Sickness

China

Search clinical trials for: topotecan hydrochloride

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